The Journal of Korean Academy of Prosthodontics (대한치과보철학회지)

The Korean Academy of Prosthodonitics (대한치과보철학회)
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Antimicrobial activity of dental polishing bur material with fluoride ion

불소이온을 함유한 연마용 버 재료의 항균력 연구

  • Jeong, Insun (Interdisciplinary Program of Biomedical Engineering, Chonnam National University Graduate School) ;
  • Kim, Ji-Hyun (Department of Prosthodontics, School of Dentistry, Chonnam National University) ;
  • Yun, Kwi-Dug (Department of Prosthodontics, School of Dentistry, Chonnam National University)
  • 정인선 (전남대학교 일반대학원 의공학협동과정) ;
  • 김지현 (전남대학교 치의학전문대학원 치과보철학교실) ;
  • 윤귀덕 (전남대학교 치의학전문대학원 치과보철학교실)
  • Received : 2020.04.01
  • Accepted : 2020.06.22
  • Published : 2020.07.31
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Abstract

Purpose: The purpose of this study is to evaluate the antimicrobial activity on the dental bur with fluoride for S. mutans. Materials and methods: 0 ppm, 300 ppm, 500 ppm, 1,000 ppm, 1,450 ppm fluoride ion is added to a specimen. S. mutans was incubated for 24 hours, the number of S. mutans were counted. Kruskal-Wallis and MannWhitney analysis were used SPSS 25.0 (IBM SPSS 25.0, Chicago, IL, USA). Results: The mean S. mutans counts of 0 ppm, 300 ppm, 500 ppm, 1,000 ppm, and 1,450 ppm were 374.0 ± 12.6, 251.0 ± 66.7, 111.4 ± 35.6, 41.6 ± 11.7 and 13.2 ± 4.6, respectively. All groups except the control and 300 ppm showed statistically significant. Conclusion: Thus, more than 500 ppm fluoride ion showed the statistically significant antimicrobial activity. 1,450 ppm group showed the highest antimicrobial activity. This study showed the clinical possibility for dental caries protection and antimicrobial activity of dental bur.

목적: 이 연구의 목적은 충치 치료시 치아의 성형이나 연마에 사용되는 연마용 버에 불소를 첨가하여 치아 우식균의 주 원인균인 S. mutans에 대한 항균력을 평가하고자 한다. 재료 및 방법: 이를 위해 불소를 0 ppm, 300 ppm, 500 ppm, 1,000 ppm, 1,450 ppm의 농도로 혼합하여 각 그룹당 5개씩 시편을 제작하였다. 시편 위에 S. mutans를 24시간 동안 배양하여 생균수를 기록하였다. 그 결과는 SPSS 25.0 (IBM SPSS 25.0, Chicago, IL, USA)를 이용하여 Kruskal-Wallis 분석을 시행하였고, 사후 분석을 위해 Mann-Whitney 분석을 시행하였다. 결과: S. mutans를 이용한 항균력 평가에서는 1,450 ppm에서는 13.2 ± 4.6, 1,000 ppm에서는 41.6 ± 11.7, 500 ppm에서는 111.4 ± 35.6, 300 ppm에서는 251.0 ± 66.7, 대조군에서는 374.0 ± 12.6의 생균수를 보였다. 이는 대조군과 300 ppm 그룹군을 제외한 모든 그룹 사이에서 통계적인 유의성을 보였다. 결론: 치과용 버 성형물에 불소이온(F-)을 500 ppm 이상의 농도로 투입했을때, S. mutans균에 대한 항균력이 통계적으로 유의하게 존재한다. 식약처에서 고시한 최대 허용치 이하의 불소 농도에서는 1,450 ppm 농도에서 96.5%의 항균력을 보였다. 이는 치과 임상에서 치아 우식증 치료를 할 때 치아 표면을 성형하고 연마하는 과정에서 추가적인 치아 우식증을 예방할 수 있는 임상적 가능성을 확인하였다.

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