• Title/Summary/Keyword: maternal effect

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A meta-analysis of exposure to particulate matter and adverse birth outcomes

  • Lamichhane, Dirga Kumar;Leem, Jong-Han;Lee, Ji-Young;Kim, Hwan-Cheol
    • Environmental Analysis Health and Toxicology
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    • v.30
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    • pp.11.1-11.19
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    • 2015
  • Objectives The objective of this study was to conduct a systematic review to provide summarized evidence on the association between maternal exposure to particulate air pollution and birth weight (BW) and preterm birth (PTB) after taking into consideration the potential confounding effect of maternal smoking. Methods We systematically searched all published cohort and case-control studies examining BW and PTB association with particulate matter (PM, less than or equal to $2.5{\mu}m$ and $10.0{\mu}m$ in diameter, $PM_{2.5}$ and $PM_{10}$, respectively) from PubMed and Web of Science, from January 1980 to April 2015. We extracted coefficients for continuous BW and odds ratio (OR) for PTB from each individual study, and meta-analysis was used to combine the coefficient and OR of individual studies. The methodological quality of individual study was assessed using a standard protocol proposed by Downs and Black. Forty-four studies met the inclusion criteria. Results In random effects meta-analyses, BW as a continuous outcome was negatively associated with $10{\mu}g/m^3$ increase in $PM_{10}$ (-10.31 g; 95% confidence interval [CI], -13.57 to -3.13 g; I-squared=0%, p=0.947) and $PM_{2.5}$ (-22.17 g; 95% CI, -37.93 to -6.41 g; Isquared=92.3%, p<0.001) exposure during entire pregnancy, adjusted for maternal smoking. A significantly increased risk of PTB per $10{\mu}g/m^3$ increase in $PM_{10}$ (OR, 1.23; 95% CI, 1.04 to 1.41; I-squared=0%, p=0.977) and $PM_{2.5}$ (OR, 1.14; 95% CI, 1.06 to 1.22; I-squared=92.5%, p<0.001) exposure during entire pregnancy was observed. Effect size of change in BW per $10{\mu}g/m^3$ increase in PM tended to report stronger associations after adjustment for maternal smoking. Conclusions While this systematic review supports an adverse impact of maternal exposure to particulate air pollution on birth outcomes, variation in effects by exposure period and sources of heterogeneity between studies should be further explored.

The Relationship between Perceived Maternal Learning Involvement and Career Preparation Behaviors among Middle School Students : The Mediating Effects of Hope (중학생이 지각하는 모의 학습관여와 진로준비행동과의 관계: 희망의 매개효과를 중심으로)

  • Geum, Kyung-Hee;Cho, Young-A
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.269-281
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    • 2017
  • Recently, the need for research into environmental and intrapsychic variables to promote active career preparation behavior is increasing, due to the increasing need to cultivate career preparation behavior starting from middle school. On the basis of this need, the purpose of this study is to identify the mediating effects of hope in the relationship between maternal learning involvement and career preparation behavior among middle school students. We surveyed 320 middle school students in W city, Gangwon-do, regarding these variables. We evaluated the results according to Baron and Kenny's (1986) mediating effect test procedure. The findings showed a significant positive correlation between positive maternal learning involvement, such as respecting their children's learning methods and providing academic information and advice, and the students' career preparation behavior and hope. However, the findings didn't show any significant correlation between negative maternal learning involvement, such as pressure for academic performance, and the students' career preparation and hope. Furthermore, hope was found to partially mediate the relationship between maternal positive learning involvement, including academic information and advice, and career preparation behavior, while fully mediating the relationship between career preparation behavior and respecting the students' learning methods. However, it did not have any mediating effect on the relationship between pressure for academic performance and career preparation behavior. These results highlight the important role that instilling hope in students, through respecting their learning methods and advising and providing the necessary academic information, plays in achieving a higher level of career preparation behavior.

Genetic and Non-genetic Factors Affecting Mortality in Lori-Bakhtiari Lambs

  • Vatankhah, M.;Talebi, M.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.4
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    • pp.459-464
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    • 2009
  • Data and pedigree information for Lori-Bakhtiari sheep used in this study were 6,239 records of lamb mortality from 246 sires and 1,721 dams, collected from 1989 through 2007 from a Lori-Bakhtiari flock at Shooli station in Shahrekord. The traits investigated were cumulative lamb mortality from birth up to 7 days, up to 14 days, up to 21 days, and up to 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12 months of age. The models included fixed factors that had significant effects and random direct genetic, maternal genetic and maternal permanent environmental effects. Variance components were estimated using the restricted maximum likelihood procedure applying three animal models with and without maternal and common environmental effects. The overall mean of cumulative lamb mortality rate was 22.95% from birth to 1 year of age, while the overall mortality rate up to 3 and from 3 to 6 months of age was 6.14% and 12.76%, respectively. The mortality rate after 6 months of age declined as the lambs grew older. The age of dam had no important effect on lamb mortality. The type of birth was more important during the preweaning period than at later ages, and lamb mortality rate was higher in twins. The year of birth, month of birth and sex of lamb significantly (p${\leq}$0.01) affected the cumulative lamb mortality rate at all ages. The least square mean of mortality during the final one-third of the lambing period was higher than the first and middle onethird of the lambing period. Male lambs were found to be at a higher risk of mortality than females. Birth weight of the lamb had a highly significant (p${\leq}$0.01) effect on lamb mortality at all ages as a quadratic regression. Direct and maternal heritability estimates of lamb mortality ranged from 0.01 to 0.13 and 0.01 to 0.05, respectively. Direct heritability increased with age of lamb, while maternal effects (genetic and common environmental) were important in the preweaning period. These results indicate that lamb mortality can be reduced first through farm management practices and secondly by genetic selection. Both animal and maternal effects should be considered in breeding programmes for reducing lamb mortality at preweaning.

Maternal Low-protein Diet Alters Ovarian Expression of Folliculogenic and Steroidogenic Genes and Their Regulatory MicroRNAs in Neonatal Piglets

  • Sui, Shiyan;Jia, Yimin;He, Bin;Li, Runsheng;Li, Xian;Cai, Demin;Song, Haogang;Zhang, Rongkui;Zhao, Ruqian
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.12
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    • pp.1695-1704
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    • 2014
  • Maternal malnutrition during pregnancy may give rise to female offspring with disrupted ovary functions in adult age. Neonatal ovary development predisposes adult ovary function, yet the effect of maternal nutrition on the neonatal ovary has not been described. Therefore, here we show the impact of maternal protein restriction on the expression of folliculogenic and steroidogenic genes, their regulatory microRNAs and promoter DNA methylation in the ovary of neonatal piglets. Sows were fed either standard-protein (SP, 15% crude protein) or low-protein (LP, 7.5% crude protein) diets throughout gestation. Female piglets born to LP sows showed significantly decreased ovary weight relative to body weight (p<0.05) at birth, which was accompanied with an increased serum estradiol level (p<0.05). The LP piglets demonstrated higher ratio of bcl-2 associated X protein/B cell lymphoma/leukemia-2 mRNA (p<0.01), which was associated with up-regulated mRNA expression of bone morphogenic protein 4 (BMP4) (p<0.05) and proliferating cell nuclear antigen (PCNA) (p<0.05). The steroidogenic gene, cytochrome P450 aromatase (CYP19A1) was significantly down-regulated (p<0.05) in LP piglets. The alterations in ovarian gene expression were associated with a significant down-regulation of follicle-stimulating hormone receptor mRNA expression (p<0.05) in LP piglets. Moreover, three microRNAs, including miR-423-5p targeting both CYP19A1 and PCNA, miR-378 targeting CYP19A1 and miR-210 targeting BMP4, were significantly down-regulated (p<0.05) in the ovary of LP piglets. These results suggest that microRNAs are involved in mediating the effect of maternal protein restriction on ovarian function through regulating the expression of folliculogenic and steroidogenic genes in newborn piglets.

The Effect of Children's Age on Married Women's Career Reinterruption (자녀 연령이 기혼여성의 경력 재단절에 미치는 영향)

  • Park, Seeun;Go, Sun
    • The Journal of Industrial Distribution & Business
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    • v.9 no.7
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    • pp.43-52
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    • 2018
  • Purpose - The main purpose of this paper is to examine the effect of children's age on maternal labor supply in Korea using survival analysis. Specifically, we focus on the career re-interruption of women having children under age 12, which has rarely been studied in the existing literature. Research design, data, and methodology - We use micro data from the Korea Labor and Income Panel Study (KLIPS) surveyed from 1998 to 2016. Instead of using a pre-school child dummy or the number of young children as an explanatory variable, 9 children's age dummies are included to capture the effect of nurturing 0 to 9 years old children. This study estimates the hazard of a woman's exiting the labor market after her first experience of the career interruption, rather than the hazard of the first career interruption itself. A Cox proportional hazard model is applied to numerically capture the impact of children's age on behavioral changes in maternal labor supply. The sample used in this analysis is women between 15 and 54 years old. Most of all, we restrict the sample to women who had at least a child between 0 and 12 years old at the time of quitting their jobs. Results - The Cox proportional hazard model estimates show a strong negative effect of a 0-year-old child on maternal labor supply. Mothers with newborns have a high hazard ratio of labor force exit after the re-entry. The hazard of women with infants is three times higher than those with children aged 10 to 18. Additionally, the results show that not only newborns, but also children in the age of school-entry have a negative impact on their mother's labor supply. Conclusions - The findings reveal that children's ages need to be properly expanded and included when analyzing the effect of children and their ages on married women's labor supply, especially on women's career re-interruption. A large negative effect of 7-year-old children on maternal labor supply found here indicates that supporting mothers with school age children as well as pre-school children is necessary to prevent mothers from leaving the labor market.

The Influence of Maternal Overprotective Parenting on the Externalizing Behaviors of Child with Disability : Testing the Moderated Mediation Effect of Child's Effortful Control through Defense Style of Mother and Child (장애아동의 외현화 행동에 어머니의 과보호 양육행동이 미치는 영향 : 어머니 및 아동의 방어유형에 의한 아동의 의도적 통제의 조절된 매개효과 검증)

  • Lee, Dong-Young
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.550-563
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    • 2021
  • This study recognizes that the externalizing problem behaviors of child with disabilities are the result of the social interaction between mother and child, and empirically verifies its systematic causal structure and multidimensional influence relationship. It was attempted to derive practical implications that can help the smooth normalization process of children's families. Therefore, 135 children with disabilities and their mothers selected by convenience sampling were targeted, and in the relationship between maternal overprotective parenting and externalizing behaviors of child, effortful control was used as a mediating variable, and defense style of mothers and children was used as a moderating variable. A Conditional Process Analysis(CPA) that can verify the moderated mediation Effect was performed by establishing a research model. As a result of the analysis, first, the overprotective parenting behavior of mother was statistically significant in both direct and indirect effects in increasing externalizing behaviors of child, and the mediation effect by effortful control was also statistically significant. Second, it was confirmed that the moderated mediation effect of effortful control by the mother's defense style was statistically significant, and the moderated mediation effect of effortful control by the child's defense style was not statistically significant. Based on the above results, assuming the importance of the influence of maternal parenting, a direct strategy for change in maternal overprotective parenting, child's Practical implications of parallel strategies with the tendency toward effective control and suboptimal strategies through the application of mothers' coping strategies were discussed.

The effect of HT7 acupuncturing on the food intake and hypothalamic neuropeptide Y expression changed by maternal separation in rat pups (신문혈(神門穴) 침자극(鍼刺戟)이 모성분리(母性分離) 스트레스로 야기된 섭식(攝食) 장애(障碍)와 시상하부 neuropeptide Y 발현에 미치는 영향)

  • Park, Hi-joon;Ryu, Yeon-hee;Hong, Mee-suk;Kim, Seung-tae;Lim, Sabina
    • Journal of Acupuncture Research
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    • v.20 no.4
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    • pp.93-101
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    • 2003
  • Objective: The purpose of this study is to find out the effect of acupuncture at HT7 (Shinmun) on the feeding behavior and hypothalamic neuropeptide Y(NPY) expression in the maternally separated rat pups. Methods: To show the effect of acupuncture, we performed maternal separation(MS) for 7 days beginning on postnatal day 14, and observed body weight, food intake, and NPY immunoreactivity in the paraventricular nucleus (PVN) of hypothalamus after acupuncturing at HT7, the end of the transverse crease of the ulnar wrist of the forepaw. Results: MS induced a significant decreases in body weight and food intake, while acupuncture treatment at acupoint HT7 showed much more improvement in those evaluations. NPY-immunoreactivity in area PVN were decreased in the MS group, but significantly increased in the HT7 group. Conclusions: These findings suggest that acupuncture has an effect on the feeding disorders caused by MS, possibly by modulating NPY expression in the PVN.

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A Structural Model for Maternal Adaptation and Family Stress in Families with Mentally Retarded Children (정신 박약 아동 어머니의 스트레스와 적응에 관한 구조 모형)

  • 이경희
    • Journal of Korean Academy of Nursing
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    • v.22 no.4
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    • pp.476-490
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    • 1992
  • This study was designed to develop and test a structural model for maternal adaptation and family stress in families with mentally handicapped children. A hypothetical model was constructed on the basis of the family stress theory developed by McCubbin etc. The model included 6 theoretical concepts and 11 paths. For the purpose of the model testing, empirical data were collected from May to August, 1992. The subjects of the study constituted 190 mothers of children in five special schools and one private institute in Seoul and Choong Nam. An SPSS PC+ and PC-LISREL 7.13 computer programs were used for descriptive and covariance structure analysis. The results of the study were as follows. (1) The hypothetical model showed itself a good fit to the empirical data [Chi - square=18.35(df=7, P=0.005), Goodness of Fit Index=0.991, Adjusted Goodness of Fit Index=0.959, Root Mean Square Residual=0.042), Non Normed Fit Index=0.90, Normed Fit Index=0.96]. (2) The results of Hypothesis testing indicated : 1) Social support(${\gamma}$$_{11}$=.238, T=2.352), Family functioning(${\gamma}$$_{12}$=.729, T=5.957) and Family life event stress(${\gamma}$$_{13}$=.125) had direct effects on situational definition. 2) Life event stress(${\gamma}$$_{23}$=.319, T=3.872) had direct effects on the effect of the handicapped child on the family. Family functioning(${\gamma}$$_{22}$=-.245) and situational definition($\beta$$_{21}$=-.335, T=3.227) had direct effects on the effect of the handicapped child on the family. 3) Situational definition($\beta$$_{31}$=-.273, T=3.493), family life event stress (${\gamma}$$_{33}$=.124, T=2.169) and the effect of the handicapped child on the family($\beta$$_{32}$=.264, T=-3.227) showed the direct effect on the maternal adaptation. The model was supported by the empirical data. Thus it was suggested that the model could be applied to family nursing care with the families with the mentally handicapped. The construction and testing of the comprehensive model seem to be the first trial in Korea.a.a.a.

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The Effect of Paternal and Maternal Helicopter Parenting on the Career Preparation Behavior of High-School Students: Sequential Mediation Effects of Academic Achievement Attribution and Career Decision-Making Self-Efficacy (아버지와 어머니의 헬리콥터 부모역할이 고등학생의 진로준비 행동에 미치는 영향: 학업성패귀인과 진로결정자기효능감의 순차적 매개효과)

  • Yoon Seo Kim;Min Ju Kang
    • Human Ecology Research
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    • v.61 no.3
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    • pp.401-414
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    • 2023
  • This study examined the sequential mediation effects of academic achievement attribution and career decision-making self-efficacy on the effect of paternal and maternal helicopter parenting on high-school students' career preparation behavior. A total of 285 (119 male and 166 female) Korean high-school students in the second grade participated in the study. Research variables were measured using the Career Preparation Behavior Scale (Kim, 1997), Helicopter Parenting Scale (LeMoyne & Buchanan, 2011), Attribution Questionnaire (Weiner, 1979), and Career Decision-Making Self-Efficacy Scale-Short Form (Betz et al., 1996). To examine the sequential mediating effect, data analysis was performed using SPSS 29.0 and PROCESS MACRO (v4.2) Model 6. The results revealed no correlations between helicopter parenting and academic failure attribution. However, higher paternal and maternal helicopter parenting were found to indirectly reduce high-school students' career preparation behavior through lower internal academic success attribution (effort and ability) and higher external academic success attribution (task difficulty and luck), which reduced career decision-making self-efficacy. These findings can be employed to develop more effective intervention programs comprising career guidance for adolescents, which emphasizes the negative effect of helicopter parenting. This study expands the research field, as previous findings on helicopter parenting mostly focus on college students.

The Longitudinal Relationship among Paternal Involvement, Maternal Parenting Stress, Psychosocial Development of Infant during Infancy and Peer Interactions during Childhood (영아기 아버지 양육참여, 어머니 양육스트레스, 영아 심리사회발달과 유아기 또래상호작용 간의 종단적 관계 분석)

  • Jang, Hyo Eun;Kim, Choon Kyung
    • Korean Journal of Child Education & Care
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    • v.18 no.1
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    • pp.77-102
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    • 2018
  • The objectives of this study were to analyze the longitudinal mediation effects of maternal parenting stress and psychosocial development of infant on the influence of paternal involvement during infancy to children's peer interactions. For these objectives, latent growth modeling was used and adapted to the data taken from the Panel Study on Korean Children(PSKC), Wave I (0-year olds) to Wave III (2-year olds) and Wave V(4-year olds) to Wave VII(6-year olds). During a total of six years, 1,018 parent responded. The major results of this study were as follows. First, maternal parenting stress(initial status) had a significant mediating effect on the influence of paternal involvement(initial status) to children's play interaction(initial status). Second, maternal parenting stress(initial status/change rate) had a longitudinal mediating eff ect on the influence of paternal involvements(initial status/change rate) to children's play disruption-disconnection interactions(initial status/change rate). Third, psychosocial development of infants(initial status/change rate) had a longitudinal mediating effect on the influence of paternal involvement(initial status/change rate) to children's play interactions(initial status/change rate). Fourth, psychosocial development of infant(initial status) had a significant mediating effect on the influence of paternal involvement(initial status) to children's play disruption-disconnection interactions(initial status). The implications of the findings of the current study and suggestions for future research were also discussed.