• Journal of Korean Society of Forest Science
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• v.101 no.3
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• pp.412-425
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• 2012

Concrete Soil Erosion Control Dam, which blocks flow of debris flow in torrential stream, are reported to lose expected functions due to structural failure and collapses, caused by poor construction, material deterioration and external impacts. In this paper, an integrity assessment technique for debris barriers was proposed, which allows preliminary detection of problems inherent in debris barriers. The proposed integrity assessment technique is a non-destructive method based on SASW method, one of surface-wave tests. In this paper, a practical procedure and analysis guidelines in applying the SASW technique to debris barrier was proposed and its validity was verified using five decrepit debris barriers older than 20-year old. As a result, the SASW method was validated for the reliable grade evaluation method for concrete soil erosion control dam, and the resulting grades turned out to agree with the results determined by Sabang Associations.

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.2
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• pp.63-70
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• 2006

Natural product compounds are the source of numerous therapeutic agents. The marine environment produces natural products from a variety of structural classes exhibiting activity against numerous disease targets including anticancer agents. Among these, pectenotoxin-2 (PTX-2), which was first identified as a cytotoxic entity in marine sponges, which depolymerizes actin filaments, was found to be highly effective and more potent to activate an intrinsic pathway of apoptosis in p53-deficient tumor cells compared to those with functional p53 both in vitro and in vivo. However, the anti-proliferative mechanism of the compound at non-cytotoxic concentrations has not yet been explored. In the current study, we sought to investigate anti-proliferation and apoptosis of PTX-2 against U937 human leukemic cells and its underlying molecular mechanism. Exposure of U937 cells to PTX-2 resulted in growth inhibition and induction of apoptosis in dose- and time-dependent manner as measured by MTT assay, fluorescent microscopy and flow cytometric analysis. The anti-proliferative effect of PTX-2 was associated with a marked increase in the expression of cyclin-dependent kinase p21 (WAF1/CIP1) mRNA which was tumor suppressor p53-independent. The increase in apoptosis was connected with a time-dependent down-regulation of anti-apoptotic Bcl-XL and inhibitor of apoptosis proteins (IAPs) family such as XIAP and cIAP-2. Though additional studies are needed, these findings suggested that PTX-2-induced inhibition of U937 cells was associated with the induction of apoptotic cell death and the results provided important new insights into the possible molecular mechanisms of the anti-cancer activity of PTX-2.

• Journal of Environmental Impact Assessment
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• v.27 no.6
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• pp.595-603
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• 2018

This study was conducted to understand the growth of attached microbial community in small and medium streams of Gyeonggi-do and the removal efficiency of fluoride with changes in growth. The sites monitoring were carried out for 12 weeks at the P1 and P2(P1 is the point where the discharge water flows. P2 is the downstream point of about 2 km flow), and investigated the water quality and the biomass analysis of the attached microbial community. The growth of the attached microbial community increased up to the 7th investigation, and it was observed that detachment phenomenon occurred. Influencing factors about growth of the attached microbial community were flow rate, velocity, and organic material(T-N & T-P). Meanwhile, fluoride content of attached microbial community also tended to increase until the 7th investigation, and decrease from the 8th. It is assumed that fluoride content has also be reduced with the detachment phenomenon of the attached microbial community. It is expected that this will contribute to the evaluation and management of the use of attached microbial community as a means of stream management. The application of techniques using the attached microbial community should include basic investigation of factors that may affect the growth of the attached microbial community and replacement of the attachment plate according to the time of removal.

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.1
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• pp.85-92
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• 2019

The purpose of this study was to compare and evaluate the cytotoxicity of 3 calcium silicate-based materials (CSMs) on stem cells from human exfoliated deciduous teeth (SHEDs). The powder of Retro $MTA^{(R)}$ (RM), $EZ-Seal^{TM}$ (EZ) and ENDOCEM $Zr^{(R)}$ (EN) was eluted with SHED culture media and then filtered. The SHEDs were cultured in the presence of the various concentrations of the eluate. To investigate the effect of the 3 CSMs on SHED proliferation, the MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay was performed. Flow cytometry analysis was also performed to identify any changes in the cellular phenotype. The absorbance values of the SHEDs cultured in the eluate of samples at a 10% concentration showed the following relation: RM > EN > EZ (p = 0.0439). However, the SHEDs maintained their mesenchymal phenotype regardless of product exposure. Although the 3 CSMs did not alter the SHED stem cell markers, EZ may be a less cytocompatible than RM and EN.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.9 no.2
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• pp.73-82
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• 1989

When the flood occurs in the alluvial rivers, the rivers adjust to the flood by means of the mechanism of the river bed variations and its morphological changes to pass that safely, the numerical model was developed to simulate the process of the alluvial river bed variation due to flood wave and carried out by the flood routing for flood wave and the sediment routing for river bed variation. The flood wave, river bed variation, and bed material size distribution may be analysed and predicted by this model. The ability of this model to predict the process of river bed response was proved by the application to the reach from Paldang dam to Indogyo site. In view of the flood analysis considering the sediment process, the effects of river bed variation for the flood routing may be negligible because the river bed variation is smaller than the unsteady flow variation during the same period. By the application of this model, it is shown that, in occurring of sequential flood events, the variation of the river bed and bed material size distribution due to flood wave is more dependent on the first flood event than the latter flood events, and that the river bed variation in this reach of the downstream Han river is dependent on the degradation and the coarsening of bed materials.

• The Journal of Engineering Geology
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• v.15 no.2 s.42
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• pp.105-121
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• 2005

Most of the landslides triggered by intensive rainfall on natural slope occur serious damages of human beings and properties. There have been many landslides since 1991 in Gyeonggi province. The influential factors are rainfall, topography, geology and soil properties. There were 660 landslides occurred by intensive rainfall as much as 250mm at Yongin and Anseong area from Tuly 19th to luly 21st,1991 This study surveyed location, topography, geology, geometry of the landslide and rainfall at the area and analyzed occurrence characteristics of the landslides. Most of the landslides occurred on the soil layer above the bed rock. They showed changes of landslide types from translational slides at the head part to flow at the central part. The landslides have relatively small magnitude of which length is shorter than 50m. In order to identify characteristics of landslides dependent on soil conditions, geotechnical properties of soil were evaluated by laboratory tests using soil samples which were collected on slided area and not-slided area. Soil properties of the slided area show high percentage of coarse material such as gravel and sand. However, soil of the not-slided area is mainly composed of fine material such as silt and clay. Permeability coefficients of the slided area are higher than those of the not-slided area.

• Korean Chemical Engineering Research
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• v.46 no.3
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• pp.585-597
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• 2008

The aim of this study was to find an analytic solution to the problem of determining the optimal capacity (lot-size) of a batch-storage network to meet demand for a finished product in a system undergoing random failures of operating time and/or batch material. The superstructure of the plant considered here consists of a network of serially and/or parallel interlinked batch processes and storage units. The production processes transform a set of feedstock materials into another set of products with constant conversion factors. The final product demand flow is susceptible to short-term random variations in the cycle time and batch size as well as long-term variations in the average trend. Some of the production processes have random variations in product quantity. The spoiled materials are treated through regeneration or waste disposal processes. All other processes have random variations only in the cycle time. The objective function of the optimization is minimizing the total cost, which is composed of setup and inventory holding costs as well as the capital costs of constructing processes and storage units. A novel production and inventory analysis, the PSW (Periodic Square Wave) model, provides a judicious graphical method to find the upper and lower bounds of random flows. The advantage of this model is that it provides a set of simple analytic solutions while also maintaining a realistic description of the random material flows between processes and storage units; as a consequence of these analytic solutions, the computation burden is significantly reduced.

• Journal of Animal Environmental Science
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• v.9 no.2
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• pp.69-78
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• 2003

In this study, the energy conversion equipment from the radiation energy to mechanical energy by using n­pentane as the operating fluid was constructed and the performance to pump the water was tested for the utilization of solar powered water pump. The equipment was designed optimally, after the theoretical analyses of the water pumping head and water quantity per cycle were done. The pentane vapour temperature in the condenser and the temperature of the outlet water from the condenser became lowered and the heat transfer rate became higher with decreasing the water inlet level to the condenser. The temperature difference between the condenser and the water tank was significant. Therefore, the distance between the water tank and condenser was recommended to be shorten and the diameter of their connecting pipe was recommended to be narrow in order to reduce the resistance of the fluid passage and improve the heat transfer rate. The amount of water pumped was 1.6­2.4 liters. Mass flow rate of the cooling water became lowered when the cooling water pipe was prolonged from the condenser to improve the heat transfer rate.

• Journal of the Korean Geotechnical Society
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• v.29 no.1
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• pp.49-59
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• 2013

Heavy rainfall intensity may cause shallow slope failures and debris flow by rill erosion and scour on land surface. The paper represents the difference between native soil (weathered soil) and reinforced soil, which is mixed by hardening agent with flyash as main material, for investigating experimental findings of rill erosion and erosion. Results obtained from artificial rainfall simulator show that erosion rate of reinforced soil mixed with hardening agent is reduced by 20% because an amount of eroded soil on slope surface is inversely proportional to the increase of soil strength. For example, rainfall of 45mm (at the elapsed time of 25mins in rainfall intensity of 110mm/hr) triggers rill erosion on native soil surface, but the rill erosion on reinforced soil surface does not even occur at 330mm rainfall (at the elapsed time of 3hrs in rainfall intensity of 110mm/hr). As a result of slope stability analysis, it was found that the construction method for reinforced soil surface would be more economical, easy and fast construction technology than conventional reinforcement method.

• Journal of Korean Society of Forest Science
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• v.88 no.2
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• pp.240-248
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• 1999

On the basis of data obtained from five forest roads collapsed due to a heavy rainfall of 1995 in Chunchon, Kangwon-do, this study was carried out to evaluate and predict the fill slope failure of forest roads with four factors of forest road structure and those of location condition by using Quantification theory(II). The results were summarized as follows ; In the structure factors of forest road, the fill slope failure was mainly occurred in longitudinal gradients less than $2^{\circ}$ or more than $4^{\circ}$, distance of surface-flow longer than 80m, fill slope length greater than 6m, and fill slope gradients steeper than $35^{\circ}$. In the factors of location condition, the failure was mainly occurred in ridge portion of road position, weathered rock and soft rock of constituent material, slope gradients in the range from $35^{\circ}$ to $45^{\circ}$, and concave and convex of longitudinal slope forms. The priority order for factors influencing on fill slope failure was ranked by fill slope length, constituent material, road position, and so on. And the rate of correct discrimination by analysis of fill slope failure was estimated at the high prediction of 86.5%.