• Journal of Trauma and Injury
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• 제18권1호
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• pp.47-52
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• 2005

Background: This study was undertaken to evaluate the clinical pattern of the patients with penetrating torso injury. We retrospectively analyzed the clinical symptoms, mechanism of injury, injury type including injured organ, and ultimate outcome of treatment. Our purpose of the study was to establish guideline of management in penetrating torso injury. Methods: This study consists of an analysis of a consecutive series of 94 patients with penetrating injury of trunk treated at one general hospital during 7year period (from January 1995 to April 2003) who was admitted through in our emergency department. All data were collected from the medical records and entered in a database for analysis on the following: age, sex, mechanism of injury, vital sign at admission, clinical outcome including hospital mortality, length of hospital stay, length of intensive care unit stay, requirement of crystalloid fluid and blood product. Results: Among 94 patients, there were 68 men and 26 women, with ages ranging from 19 to 82 years (average 38.2 years). The most frequent mechanism of injury was violence by others including rob (n=54, 57.4%) followed by suicidal attempt (n=24, 25.5%) and accidental injury (n=16, 17.0%). No injury was inflicted from gun. In 37 patients, systolic blood pressure at admission was under 90mmHg. The time interval from injury to admission, and from admission to operation was 57.8minutes and 4hour 12minutes each. Laparotomy was required in 70 patients, thoracotomy in 5 patients, and 3 patients required thoracotomy and laparotomy. Among 94 patients, an average of 1.7 organs were injured. The small bowel and colon were the organs most commonly wounded followed by liver, mesentery, pleura. Of the 94 patients, 6 died for an overall mortality rate of 6.4%, and two of them were not related with hemorrhage. The average length of hospital stay was 18.1 days, and 40 patients required ICU care. Conclusion: Of the 94 patients who were admitted from penetrating torso injury, no patient was injured from firearm. Overall mortality rate was 6.4%. In our hospital, firearm injury was relative rare.

• 환경생물
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• 제36권1호
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• pp.62-72
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• 2018

진주만 해역에서의 식물플랑크톤 시공간적 군집 분포와이를 조절하는 환경요인을 파악하기 위해 물리, 화학적인 환경조사와 더불어 UPLC-CHEMTAX program을 이용한 식물플랑크톤 군집특성분석을 수행하였다. 본 연구해역에서의 Chlorophyll ${\alpha}$ 농도는 평균 $1.84{\mu}gL^{-1}$ ($0.13{\sim}9.03{\mu}gL^{-1}$)로 얕은 수심과 조석의 혼합이 활발한 본 연구해역에서 겨울철 식물플랑크톤 현존량이 높게 나타났다. 또한 본 연구해역에서 나타난 주요 식물플랑크톤 군집 중 규조류가 연구기간 동안 평균 77.1%로 대부분 우점하였으나, 하계 (6월, 7월, 8월) 은편모류 (7.7~18.8%), 담녹조류 (7.8~17.3%), 와편모류 (4.9~13.9%)의 분포비율을 나타내었다. 특히 은편모류와 담녹조류는 현미경으로 검경하기 어려운 군집이며, 동기간 보고된 현미경 관찰결과에도 나타나지 않아 향후 이들 군집에 대한 면밀한 조사가 필요할 것으로 판단되었다. 본 연구를 통해 UPLC 활용하여 진주만 어장 생태계의 기초 생산자이자 먹이원으로 작용하는 식물플랑크톤의 생물량 및 시공간적 변동특성을 확인할 수 있었다. 아울러 현미경 검경으로 확인하기 어려운 은편모류와 담녹조류 군집이 하계에 상대적으로 높은 비율을 나타내는 것을 UPLC로 확인할 수 있었고, 이러한 결과는 향후 1차 생산에 관여하는 식물플랑크톤의 계절 변화의 기초정보로 유용하게 이용될 것이다.

• Journal of Microbiology and Biotechnology
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• 제23권8호
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• pp.1076-1083
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• 2013

Seventeen compounds derived from traditional Chinese medicines (TCMs) were tested for their antiviral activity against porcine reproductive and respiratory syndrome virus (PRRSV) in vitro. Visualization with the cytopathologic effect (CPE) assay and the 3-(4, 5-dimethyithiazol-2-yl)-2,5-diphenyltetrazolium bromide test were used to determine the 50% cytotoxic concentration ($CC_{50}$) and 50% effective concentration ($EC_{50}$) in cultured Marc-145 cells. Among the tested compounds, chlorogenic acid and scutellarin showed potential anti-PRRSV activity. The $EC_{50}$ values were $270.8{\pm}14.6{\mu}g/ml$ and $28.21{\pm}26.0{\mu}g/ml$ and the selectivity indexes were >5.54 and 35.5, respectively. The time-of-addition and virucidal assay indicated that the anti-PRRSV activity of the two compounds could be due to their inhibiting the early stage of virus replication and/or inactivating the virus directly. The inhibition of the virus attachment was not observed in the adsorption inhibition assay. The inhibition ratios of chlorogenic acid and scutellarin were, respectively, 90.8% and 61.1% at the maximum non-cytotoxic concentrations. The results have provided a basis for further exploration of their antiviral properties and mechanisms in vivo. We believe that the chlorogenic acid and scutellarin have a great potential to be developed as new anti-PRRSV drugs for clinical application.

• 한국환경보건학회지
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• 제46권2호
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• pp.136-149
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• 2020

Objectives: The purpose of this study was to perform an aggregate human risk assessment for benzene in an industrial complex using the CalTOX model and to improve the reliability and predictability of the model by analyzing the uncertainty and sensitivity of the predicted assessment results. Methods: The CalTOX^TM 4.0 beta model was used to evaluate a selected region, and @Risk 7.6 software was used to analyze uncertainty and sensitivity. Results: As a result of performing the aggregate risk assessment on the assumption that 6.45E+04 g/d of benzene would be emitted into the atmosphere over two decades, 3% of the daily source term to air remained in the selected region, and 97% (6.26E+04 g/d) moved out of the region. As for exposure by breathing, the predicted LADD_inhalation was 2.14E-04 mg/kg-d, and that was assessed as making a 99.99% contribution to the LADD_total. Regarding human Risk_cancer assessment, the predicted human cancer risk was 5.19E-06 (95% CI; 4.07E-06-6.81E-06) (in the 95th percentile corresponding to the highest exposure level, a confidence interval of 90%). As a result of analyzing sensitivity, 'source term to air' was identified as the most influential variable, followed by 'exposure time, active indoors (h/day)', and 'exposure duration (years)'. Conclusions: As for the results of the human cancer risk assessment for the selected region, the predicted human cancer risk was 5.19E-06 (95% CI; 4.07E-06-6.81E-06) (in the 95th percentile, corresponding to the highest exposure level, a confidence interval of 90%). As a result of analyzing sensitivity, 'source term to air' was found to be most influential.

• 한국응용곤충학회지
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• 제58권4호
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• pp.313-317
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• 2019

우리나라에서 노린재류는 여러 과수에 피해를 주는 해충이다. 우리는 핵과류 4종(매실, 체리, 자두, 복숭아)의 과실에 발생하는 노린재의 종류와 상대적인 풍부도를 2017년부터 2019년까지 3년에 걸쳐 조사하였다. 핵과류 과수원에서 과실에 발생하는 노린재는 가시노린재, 알락수염노린재, 썩덩나무노린재, 갈색날개노린재 등 4종이었다. 조사기간 중에 4종의 상대적인 풍부도는 썩덩나무노린재(65%), 갈색날개노린재(26%), 가시노린재(7%), 알락수염노린재(2%) 순이었다. 썩덩나무노린재는 매실, 체리, 복숭아에서 우점종이었던 반면, 자두에서는 갈색날개노린재가 가장 많이 발견되었다. 핵과류 과실에 발생하는 노린재는 성충이 81%이었고 약충이 19%이었다. 한편 핵과류 과종별 노린재의 발생은 생육초기보다는 생육후기에 더 많았다. 이상의 결과를 종합해 보면, 핵과류 과수원에서는 수확기에 썩덩나무노린재와 갈색날개노린재의 관리방안에 대한 전략이 개발되어야 할 것으로 보인다.

• 콘크리트학회논문집
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• 제19권2호
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• pp.189-197
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• 2007

터널 라이닝은 대형 화재 등과 같은 고온에 노출될 경우, 폭렬이 발생하고 이로 인해 급격한 온도 전달 및 내력 저하로 구조체 붕괴의 원인이 될 수 있다는 것이 여러 사례를 통해 보고되고 있다. 본 연구는 터널라이닝의 내화뿜칠 재료로 매우 적합할 것으로 판단되는 고인성 고내화성 시멘트 복합체(FR-ECC)를 개발하고 이의 역학적 특성 및 내화 성능을 평가하고자 하였다. 이를 위하여 FR-ECC에 있어서의 배합 요인을 실험 변수로 내화 시험을 실시하였으며 비정상 온도 분포 해석 기법(nonlinear transient heat flow analysis)을 이용하여 이를 해석적으로 묘사 검증되었다. 또한, 실험 결과를 통해 검증된 해석 기법을 이용하여 터널라이닝에 대한 열전달 해석을 수행하여 FR-ECC를 내화 2차 라이닝재로 이용하는 경우의 거동 특성을 분석하였다. 실험 결과 내화 성능을 향상시키기 위한 FR-ECC의 최적 배합은 PVA 섬유 또는 PP 섬유 혼입률 $V_f=2.0%$, 다공성 세라믹재 혼입률 $V_C=3.6%$, 공기량 $V_A=15%$로 나타났으며, 검증된 비정상 온도 분포 해석 기법을 이용하여 기존 터널에 40mm FR-ECC를 추가 라이닝 한 경우에 대한 해석 결과, 콘크리트 및 철근의 온도 분포가 모두 $350^{\circ}C$ 이내에서 제어되어 터널 내 콘크리트 및 철근에 대한 화재 피해를 방지할 수 있을 것으로 판단되었다.

• 한국의상디자인학회지
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• 제10권3호
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• pp.27-36
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• 2008

This article aims to identify the current status of outsourced production of Dongdaemun brands and to discover the consumers' perception of those outsourced products, their degree of satisfaction, and preference in purchasing those products. Moreover, the strengths and weaknesses of the outsourced products, as perceived by the consmers, have been identified, and specific methods and directions for efficient overseas outsourcing of Dongdaemun brands are suggested. This study also contains experimental works, in which I have prepared questionnaires, and my advisor have collected data. This survey was conducted on corporation managers, who directly operated clothing stores in Dongdaemun Market in December 2007. The collected data have been analyzed using SPSS 12.0 with various techniques such as t-test, paired t-test, frequency analysis and $X^2$-test. The results are summarized as the following: a) Comparison of the current outsourcing status of Dongdaemun brands showed that only eight out of the total 42 investigated companies have actually been outsourcing the production of their clothes. The biggest advantage of outsourcing was the reduced unit production cost, while low quality of products, delayed production, difficulty of control and management were shown as its disadvantages; b) the reason for purchasing clothes in Dongdaemun Market was to buy various clothing products. Comparing these reasons among different groups showed that there was a significant discrepancy in terms of trend design and copy design, in which wholesale consumers had shown a higher degree than retail consumers; c) and the preference for outsourced products of Dongdaemun brands was negative in both wholesale consumers (71.05%) and retail consumers (83.54%), as they both prefer clothes manufactured in Korea. Both groups selected the expensive price as the biggest disadvantage of Korean products, and picked design as the biggest strength of the outsourced clothes. Furthennore, both wholesale consumers (63.16%) and retail consumers (74.68%) selected Italy as the most preferred country for outsourcing clothing production. in which their reason had been their expectation for good product quality. The least preferred country for both wholesale (47.37%) and retail (50.63%) consumers was China, a country which they expected poor product quality.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권2호
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• pp.143-149
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• 2004

Background: Some clinical trials have reported that a new analgesic combination of tramadol and acetaminophen provides good efficacy in various pain models. For the more clinical uses of this agent, comparisons about the onset of analgesia and analgesic efficacy in the acute state of pain with the other drugs known as strong analgesics were needed. Purpose: The goal of this study was to compare the times to onset of analgesia and the other analgesic efficacy of 75 mg tramadol/650 mg acetaminophen and 20 mg codeine/500 mg acetaminophen/400 mg ibuprofen in the treatment of acute pain after oral surgery. Patients and Methods: Using a randomized, single-dose, parallel-group, single-center, and active-controlled test design, this clinical study compared the times to onset of analgesia using a two-stopwatch technique and the other analgesic efficacy of the single-dose tramadol/acetaminophen and codeine/acetaminophen/ibuprofen. These were assessed in 128 healthy subjects with pain from oral surgical procedures involving extraction of one or more impacted third molars requiring bone removal. From the time of pain development, the times to onset of perceptible and meaningful pain relief, pain intensity, pain relief, an overall assessment, and adverse events of the study medications were recorded for 6 hours. Results: The demographic distribution and baseline pain data in the two groups were statistically similar. The median times to onset of perceptible pain relief were 21.0 and 24.4 minutes in the tramadol/acetaminophen and codeine/acetaminophen/ibuprofen groups respectively and those to onset of meaningful pain relief were 56.4 and 57.3 minutes, which were statistically similar. The other efficacy variables such as mean total pain relief (TOTPAR) and the sum of pain intensity differences (SPID) were also similar in the early period after pain development and drug dosing. The safety of tramadol/acetaminophen was well tolerated and very comparable to that of codeine/acetaminophen/ibuprofen. Conclusions: In this acute dental pain model, the onset of analgesia and analgesic efficacy of tramadol/acetaminophen was comparable to that of codeine/acetaminophen/ibuprofen. These results showed that tramadol/acetaminophen was recommendable for fast and effective treatment in the management of postoperative acute pain.

• 한국산림과학회지
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• 제109권1호
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• pp.72-80
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• 2020

목재수확작업의 경제성을 분석하기 위한 방법은 기계비용법(machine rate method)과 현금흐름법(cash-flow method: CFM)으로 구분할 수 있다. 본 연구에서는 CFM을 이용하여 낙엽송 임분에서 HAM300 전간집재작업의 경제적 타당성 분석을 실시하였다. 즉, 연간 작업일수(50, 100, 150, 200일/년)와 작업 생산성 변화(효율성 40% 개선 효과)에 대하여 집재작업의 경제적 타당성을 평가하고자 하였다. 분석방법으로는 순현재가치법(net present value: NPV)과 자본회수기간법(pay-back period)을 이용하였다. 연간 작업일수가 150일 이상인 조건에서 NPV의 값이 0보다 크기 때문에 경제적 타당성이 충분한 것으로 나타났으며, 이 때 자본회수기간은 3.65년 이하로 분석되었다. 작업생산성(㎥/scheduled machine hour)이 40% 증가하는 시나리오에서는 연간 작업일수가 100일인 조건에서도 현금흐름이 안정적이며, 경제적 효과가 큰 것으로 나타났다. 하지만, 연간 작업일수가 50일 이하인 경우에는 집재작업의 수익성이 악화되어 투자에 대한 의사결정이 어려운 것으로 분석되었다. 결과적으로, HAM300 집재작업은 수익성이 있는 작업조건(연간작업일수: 100일 이상, 연간작업량: 5,000 ㎥)이 지속적으로 확보가 가능하다고 판단되는 작업조건에서 투자에 대한 결정이 이루어져야 한다.

• 생태와환경
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• 제36권3호통권104호
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• pp.257-268
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• 2003

하천형 저수지 (팔당호)에서 탁도의 변동과 탁수에 포함된 입자의 분포를 파악하기 위해 1999${\sim}$2001년동안 일 모니터링 하였다. 수중 탁도와 탁수의 입자 분포는 강우 패턴의 기후학적 요인과 유입${\cdot}$방류량의 수문학적요인 영향이 중요하게 작용하였다. 탁도의 연 평균 농도는 매년 비슷하였고, 연중 10 NTU 이하는 85.0%를 차지하였다. < 5 NTU는 겨울철${\sim}$봄철에, 5${\sim}$10 NTU범위는 가을철에, > 20 NTU이상은 여름철에 우점하는 계절적 특성이 뚜렷하였다. 탁도의 최대값은 7월 하순${\sim}$8월 초순에 발생하였고, 수문 변동과 달리 1999년에서 2001년으로 갈수록 증가하였다. 특히, 2001년에 저수지의 최대탁도는 하류로 갈수록 더욱 증가하는 양상이 현저하였다. 또한, 1999년에는 유량과 탁도가 완만하게 증감되었으나, 2000년과 2001년에는 초기에 급격하게 증가한 후 유량이 커지면서 감소하는 패턴을 보였다. 탁수의 입자는 전 정점에서 clay성분으로 갈수록 분포가 더욱 조밀하였을 뿐만 아니라 차지하는 비율도 높았다. 탁수에서clay는 63.9${\sim}$66.6%, silt는 33.4${\sim}$36.1% 범위로서 총 입자수의 98.9${\sim}$100%범위를 차지하였고, sand는 1.1%이내이었다. 하천형 저수지에서 수중 탁도는 비강우기에 플랑크톤의 생물량에 의한 영향을 많이 받으나 강우기에는 토양 성분을 근간으로 하는 무기입자의 양과 상대적 비율이 매우 우세한 것으로 평가되었다.