• Molecules and Cells
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• v.25 no.4
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• pp.494-503
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• 2008

Many therapeutic glycoproteins have been successfully generated in plants. Plants have advantages regarding practical and economic concerns, and safety of protein production over other existing systems. However, plants are not ideal expression systems for the production of biopharmaceutical proteins, due to the fact that they are incapable of the authentic human N-glycosylation process. The majority of therapeutic proteins are glycoproteins which harbor N-glycans, which are often essential for their stability, folding, and biological activity. Thus, several glyco-engineering strategies have emerged for the tailor-making of N-glycosylation in plants, including glycoprotein subcellular targeting, the inhibition of plant specific glycosyltranferases, or the addition of human specific glycosyltransferases. This article focuses on plant N-glycosylation structure, glycosylation variation in plant cell, plant expression system of glycoproteins, and impact of glycosylation on immunological function. Furthermore, plant glyco-engineering techniques currently being developed to overcome the limitations of plant expression systems in the production of therapeutic glycoproteins will be discussed in this review.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.34 no.4
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• pp.443-451
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• 2016

Globally, landslides triggered by natural or human activities have resulted in enormous damage to both property and life. Recent climatic changes and anthropogenic activities have increased the number of occurrence of these disasters. Despite many researches, there is no standard method that can produce reliable prediction. This article discusses the process of landslide susceptibility mapping using various methods in current literatures and applies the FR (Frequency Ratio) method to develop a susceptibility map for the 2015 earthquake region of Sindhupalchowk, Nepal. The complete mapping process describes importance of selection of area, and controlling factors, widespread techniques of modelling and accuracy assessment tools. The FR derived for various controlling factors available were calculated using pre- and post- earthquake landslide events in the study area and the ratio was used to develop susceptibility map. Understanding the process could help in better future application process and producing better accuracy results. And the resulting map is valuable for the local general and authorities for prevention and decision making tasks for landslide disasters.

• 대한예방의학회:학술대회논문집
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• 1996.10a
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• pp.3-26
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• 1996

Epidemiology and preventive medicine are changing together with Population and health and with ever expanding medical and non medical technologies. New technologies make epidemiology methodologically more sophisticated, but such advances risk overshadowing epidemiology's most important role: raising questions, providing answers, and helping the medical decision-making at ail levels of prevention. Epidemiology also plays a major role in the evaluation of new and other technologies whose effectiveness is poorly known. Epidemiological approaches, methods, techniques, and interpretations are widely used in new and rapidly expanding fields of medicine: research evaluation and synthesis (meta-analysis), establishment of guidelines for clinical preventive practices, new medical technology assessment, guidelines for national and international health policies, evidence-based medicine, outcomes research and disease management ('population-based' medicine and quality of care improvement). In the nearest future, infectious and noninfectious diseases may cease to be almost the sole subjects of epidemiology and they may share their place with other mass phenomena of the next millennium, such as medical practices and care, or political, social and economic actions and their consequences. Not only will primary, secondary, and tertiary Prevention will remain in the epidemiological mainstream, but health protection and health promotion will require perhaps a redefinition of epidemiology in these domains. Epidemiology and preventive medicine are both subjects of medical ethics and dilemma for right choices.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.40 no.4
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• pp.27-33
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• 2008

Polyethylene terephtahalate has been used in several areas such as fiber, film, bottle, and disposable products. Production of PET has been rapidly increasing these days. Since PET is a semi-permanent material, it has a non-biodegradable character in itself. Wasted PET products can cause serious environmental problems. Many countries around the world impose environmental legal restrictions over their abandonments. Many researches on the enviromental influence factors and treatment techniques of the wasted PET have been carried out. The main objective of this study is to develop a new sizing agent using recycling PET and improve its internal sizing effect. Dried powder of PET was used to make the modified PET. After extracting water-dispersible PET by subcritical hydrolysis, polyester resins have been extracted and triphenyl phosphate(TPP) has been added to obtain optimal internal sizing agent. It was found that the optimum dosage of TPP was 2% (per PET weight) and the hydrolysis temperature was independent on making the modified PET.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.126-132
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• 2006

In this paper, we aim to control the sound and vibration spatially, so that a desired physical variable is enhanced within a zone we select. This is somewhat analogous to have manipulators that can draw wave shape in any place we want. Brightness and contrast control have shown that such a manipulation is possible by controlling multiple sources[J.-W. Choi and Y.-H. Kim, J. Acoust. Soc. Am. 111(4), 2002]. In particular, the acoustic brightness control seeks a way to increase loudness of sound over a chosen area, and the contrast control aims to enhance loudness difference between two neighboring regions. This enables us to manipulate spatial distribution of sound by making two different kinds of zone ? the bright and dark zone- at the same time. The primary focus of this study is to unit the theoretical formulation of the brightness and contrast control and to find a link between these methods, as well as its relation to other conventional techniques. It is also shown that we can generate various shape of wave field by transforming the domain we consider.

• Proceedings of the Korean Society of Crop Science Conference
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• 2005.08a
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• pp.100-113
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• 2005

Leaf color and plant vigor are key indicators of crop health. These visual plant attributes are frequently used by greenhouse managers, producers, and consultants to make water, nutrient, and disease management decisions. Remote sensing techniques can quickly quantify soil and plant attributes, but it requires humans to translate such data into meaningful information. Over time, scientists have used reflectance data from individual wavebands to develop a series of indices that attempt to quantify things like soil organic matter content, leaf chlorophyll concentration, leaf area index, vegetative cover, amount of living biomass, and grain yield. The recent introduction of active sensors that function independent of natural light has greatly expanded the capabilities of scientists and managers to obtain useful information. Characteristics and limitations of active sensors need to be understood to optimize their use for making improved management decisions. Pot experiments involving sand culture were conducted in 2003 and 2004 in a green house to evaluate corn and red pepper biomass. The rNDVI, gNDVI and aNDVI by ground-based remote sensors were used for evaluation of corn and red pepper biomass. The result obtained from the case study was shown that ground remote sensing as a non-destructive real-time assessment of plant nitrogen status was thought to be a useful tool for in season crop nitrogen management providing both spatial and temporal information.

• Applied Microscopy
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• v.38 no.2
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• pp.73-79
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• 2008

In Biology, Studies Using Electron Microscopy for making Cell Structure to 3D reconstruction very fast development. Recently, by using Cryo fixation, we can see cell 3D structure without structural change, instead of using chemical fixation which can change cell structure. Before using this technology, we could understand cell structures only in 2D images. But now, through cryo-ET, 3D reconstruction of cell structure without artificial structure changes can be possible and this technology will give us many advantages in Drug delivery and Nanothechnology.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2004.11a
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• pp.367-372
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• 2004

Highway have to be constructed under thorough investigation about function, economy, safety of the traffic and environment, because they are needing huge budget for construction and management as important facilities of the social overhead capital in the national economics. Initially the construction of roads becomes effective the plan, the design, construction phase. The design is foundation of accomplishment of the roads operation, the results of the design operation come to much effect a nation when using roads. Especially ancient design methods were not expected for visual effects as attaching weight to 2-dimensional drawing from flat. Therefore, it is difficult to recognize troubles happened during the work operation besides, many troubles are solved by modification of drawings as situations. For solving of those of the problems, it is emphasize on visual effect through introduction of 3-dimensional design from the initial phase. In case of national conditions, limited national land has caused increasing weight for construction of the roads through cities as the urban centered development. thereupon, citizens are increasing concern about the right of the light and the environmental effect, road designs and construction of the structures under agreement with local residents cause to make troubles. The analysis of 3-dimensional design is necessary as intermediation for decision making. In this study, Virtual reality techniques in 3-dimensional roads design are expected to visual effect on the publishing Internet Web, find problems in first phase and make decision between users and people having civil appeal.

• The Korean Journal of Health Service Management
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• v.5 no.3
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• pp.123-132
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• 2011

To evaluate the impact of avoidable mortality on the changes in life expectancy at birth in Korea. Standard life table techniques and the Arriaga method were used to calculate and to decompose life expectancy changes by age, effects and groups of causes of avoidable mortality among two periods(1990-2000 and 2000-2009). A list of causes of avoidable mortality reached by consensus and previously published in Spain was used. Mortality in young adults produced a reduction in life expectancy at birth during the 1990-2000, but there was an important increase in life expectancy at birth during the 2000-2009; in both cases, this was the result of factors amenable to health policy interventions. The highest improvement in life expectancy at birth was due to non-avoidable causes, but avoidable mortality through health service interventions showed improvements in life expectancy at birth in those elderly people than 1 year and in those younger. Making a distinction between several groups of causes of avoidable mortality and using decomposition by causes, ages and effects allowed us to better explain the impact of avoidable mortality on the life expectancy at birth of the whole population and gave a new dimension to this indicator that could be very useful in public health.

• Journal of Environmental Impact Assessment
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• v.9 no.3
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• pp.185-202
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• 2000

Uncertainty and variability in Life Cycle Assessment(LCA) have been significant key issues in LCA methodology with techniques in other research area such as social and political science. Variability is understood as stemming from inherent variations in the real world, while uncertainty comes from inaccurate measurements, lack of data, model assumptions, etc. Related articles in this issues were reviewed for classification, distinguish and elaboration of probabilistic/stochastic health risk analysis application in LCA. Concept of focal zone, streamlining technique, scenario modelling and Monte Carlo/Latin Hypercube risk analysis were applied to the uncertainty/variability analysis of health risk in LCA. These results show that this general framework of multi-disciplinary methodology between probabilistic health risk assessment and LCA was of benefit to decision making process by suppling information about input/output data sensitivity, health effect priority and health risk distribution. There should be further research needs for case study using this methodology.