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High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

  • Jung, Sunyoon;Lee, Mak-Soon;Shin, Yoonjin;Kim, Chong-Tai;Kim, In-Hwan;Kim, Yangha
    • Preventive Nutrition and Food Science
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    • v.20 no.4
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    • pp.253-259
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    • 2015
  • Chronic low-grade inflammation is associated with obesity. This study investigated effect of high hydrostatic pressure extract of red ginseng (HRG) on inflammation in rats with high-fat (HF) diet induced obesity. Male, Sprague-Dawley rats (80~110 g) were randomly divided into two groups, and fed a 45% HF diet (HF) and a 45% HF diet containing 1.5% HRG (HF+HRG) for 14 weeks. At the end of the experiment, the serum leptin level was reduced by the HRG supplementation. The mRNA expression of genes related to adipogenesis including peroxisome proliferator-activated receptor-gamma and adipocyte protein 2 was down-regulated in the white adipose tissue (WAT). The mRNA levels of major inflammatory cytokines such as tumor necrosis factor-${\alpha}$, monocyte chemoattractant protein 1, and interleukin-6 were remarkably down-regulated by the HRG in WAT. These results suggest that HRG might be beneficial in ameliorating the inflammation-associated health complications by suppressing adipogenic and pro-inflammatory gene expression.

Comparison of Notation Items for Chemical Occupational Exposure Limits (화학물질에 대한 직업적 노출기준의 표기 항목 비교)

  • Phee, Young Gyu;Kim, Seung Won;Ha, Kwonchul
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.2
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    • pp.226-235
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    • 2020
  • Objectives: This study was to investigate the signs and notations of skin absorption, carcinogenicity, germ cell mutagenicity, and reproductive toxicity in the occupational exposure limits of Korea and of other advanced countries. Methods: Information on occupational exposure limits in Korea, the USA, the UK, Germany, and Japan was investigated through the Internet, and items marked as carcinogenicity and skin absorption were compared by country. Results: Legal occupational exposure limits have been greatly simplified. However, in the case of HSE WEL, skin absorption, carcinogenicity classification, sensitization, and in the case of DFG MAK, skin absorption, carcinogenicity, pregnancy risk group, germ cell mutagenicity, airway and skin sensitization, photo contact sensitization, and vapor pressure were provided. Conclusions: It is desirable to indicate the carcinogenicity and skin absorption within permissible limits, and to include information on critical effects in chemical substance exposure limits to uphold the right to know of industrial hygienists and workers in Korea. It is also necessary to clarify the precautions, limitations and protections for skin absorption.

The first record of Bidens radiates var. radiates in Korea (한국 미기록 식물: 삼잎구와가막사리 (Bidens radiata var. radiata))

  • Hong, Suk-Pyo;Kim, Sun-Yu
    • Korean Journal of Plant Taxonomy
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    • v.38 no.4
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    • pp.503-507
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    • 2008
  • During the systematic study of the genus Bidens L. (Asteraceae) in Korea, we found two specimens collected from Bujeon Plateau, Hamgyungnam-do, which are recognized as a new taxon (B. radiata Thill. var. radiata) for the flora of Korea. The Korean name for this taxon is newly designated as 'Sam-ip-gu-wa-ga-mak-sa-ri'. The close relative of this taxon is B. radiata Thill. var. pinnatifida (Turcz. ex DC.) Kitam., but B. radiata var. radiata can be distinguished from B. radiata var. pinnatifida by having mostly 3-parted and lanceolate lobe of leaf. The key for varieties of B. radiata is given.

Surface-enhanced Raman Spectroscopy of Quinomethionate Adsorbed on Silver Colloids

  • Kim, Mak-Soon;Kang, Jae-Soo;Park, Si-Bum;Lee, Mu-Sang
    • Bulletin of the Korean Chemical Society
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    • v.24 no.5
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    • pp.633-637
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    • 2003
  • We have studied the surface-enhanced Raman spectroscopy (SERS) spectrum of quinomethionate (6-methyl-1,3-dithiolo[4,5-b]quinoxalin-2-one), which is an insecticide or fungicide used on vegetables and wheat. We observed no signals in the ordinary Raman spectra of solid-state quinomethionate, but when it was adsorbed on a colloidal silver surface, strong vibrational signals were obtained at a very low concentration. The SERS spectra were obtained by silver colloids prepared by the Creighton et al. method. The influence of pH and the aggregation inductors ($Cl^-,\;Br^-,\;I^-,\;F^-$) on the adsorption mechanism was investigated. Two different adsorption mechanisms were deduced, depending on the experimental conditions: The one N atom or two N atoms are chemisorbed on an Ag surface. An important contribution of the chemical mechanism was inferred when the one N atom was perpendicularly adsorbed on a surface. It is possible that quinomethionate can be detected to about $10^{-5}$ M.

A Study on Distribution Property of Organic Pollutants in Southwest Coastal Waters (서남해 연안해역의 유기오염물질 분포특성에 관한 연구)

  • Han Sang-Kuk;Park Ji-Young;Lee Moon-Hee
    • Journal of Environmental Science International
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    • v.14 no.6
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    • pp.597-603
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    • 2005
  • In this study, we try to determine the distributive property in southwest coastal waters, such as K wang-yang bay, Ka-mak bay, Yeo-ja bay, Wan-do, Hea-nam, Young-gwang, and Mok-po, using simultaneous analytical method of 310 chemicals. The results were detected tens of the organic pollutants in sampling sites, and the major chemicals detected were CH type chemicals such as aliphatic, polycyclic compounds and were CHN(O) type chemicals such as aromatic amines, nitro compounds, In particular, pesticides were mainly detected in summer, phenols and phthalate esters were not seasonal effect. Also, a number of aromatic chemicals were detected in Kwang-yang bay, From the results of this study, we confirmed that it is mainly contaminated in summer and the pesticide chemicals are the major pollutants in southwest coastal waters.

The Relationships between Job Characteristics and Empowerment, Organizational Commitment of Physical Therapist to Professionalism of Rehabilitation Service (재활의료서비스 전문성을 위한 물리치료의 직무특성과 임파워먼트 및 조직몰입 간의 관계)

  • Lim, Jeong-Do;Jang, Mak-Sook;Lee, Yong-Chul;Jung, Yong-Mo
    • Journal of the Korean Society of Physical Medicine
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    • v.5 no.2
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    • pp.183-192
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    • 2010
  • Purpose : This study purposes to suggest some basic data for the efficiency of a hospital management by drawing out the efficient ways to manage manpower to professionalism of rehabilitation service. Methods : The study used the questionnaire written by respondents themselves, and conducted the regression analysis on the relationships among the job characteristics, the empowerment and organizational commitment. Rusults : Among job characteristics, the wage was the influential factor on the empowerment(psychological, structural), and the specialty physical therapist license was the factor affecting on the psychological empowerment. Among the psychological empowerment factors, the higher meaning of his/her existence, the lower self-decision level, the higher structural empowerment are, the higher organizational commitment was. Conclusion : There were not identified any significant job characteristics influencing on the organizational commitment. Among the structural empowerment factors, the apply of job performance was the largest factor affecting on the organizational commitment.

Preparation and Properties of New Di-N-alkylated 14-Membered Tetraaza Macrocycles and Their Nickel(II) and Copper(II) Complexes

  • Gang, Sin Geol;Song, Jeong Hun;Hwang, Dong Mak;Kim, Gi Mun
    • Bulletin of the Korean Chemical Society
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    • v.21 no.11
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    • pp.1106-1110
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    • 2000
  • New 14-membered tetraaza macrocycles 1,8-diallyl-3,5,7,7,10,12,14,14-octamethyl-1,4,8,11-tetraazacyclotetradecane $(L^2)$ and 1,8-bis(n-propyl)-3,5,7,7,10,12,14,14-octamethyl-1,4,8,11-tetraazacyclotetradecane $(L^3)$ have been prepared by direct react ion of 2,5,5,7,9,12,12,14-octamethyl-1,4,8,11-tetraazacyclotetradecane $(L^1)with$ allyl bromide or n-propyl bromide. The nickel(II) and copper(II) complexes of $L^2andL^3have$ been prepared. The macrocycles show high copper(II) selectivity against nickel(II) ion in methanol solutions containing water. The wavelengths (ca. 505 nm) of the d-d bands for the nickel(II) complexes are extraordinarily longer than those for the complexes of $L^1and$ other related di-N-alkylated 14-membered tetraaza macrocycles. Crystal structure of $[NiL^2](ClO4)_2$ shows that the average Ni-N bond distance $(1.992\AA)$ of the complex is distinctly longer than those of other related nickel(II) complexes. Effects of the N- and C-substituents on the properties of the macrocyclic compounds are discussed.

First Record of Ptereleotris evides (Gobiiformes: Microdesmidae) from the Southern Jejudo Island, Korea (제주도 남부 해역에서 채집된 Ptereleotris evides (망둑어목: 청황문절과) 한국 첫기록)

  • Min-Yeong Im;Hyuck Joon Kwun;Jin-Koo Kim
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.4
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    • pp.569-574
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    • 2023
  • A single specimen (30.35 mm standard length) of Ptereleotris evides was collected from the southern coast of Jejudo Island, Korea, in September 2017 during a skin diving outing. Ptereleotris evides is characterized by having a slightly elongated body, six spines on the 1st dorsal fin, one spine and 25 soft rays on the 2nd dorsal fin, 22 pectoral fin rays, one spine and four soft rays on the pelvic fin, one spine and 25 soft rays on the anal fin, and no disc in pelvic fin. This species differs from the congeneric species, P. hanae and P. heteroptera in having no elongated rays on the caudal fin and a black spot at the ventral margin of the caudal peduncle, respectively. Molecular analysis results based on mitochondrial DNA cytochrome c oxidase subunit I (COI) sequences showed that our specimen almost corresponded to P. evides (99.82%) sequences from registered at the NCBI. As this is the first record of P. evides in Korean waters, we propose a new Korean name for it, "Ga-mak-cheong-hwang-mun-jeol".

A PRELIMINARY STUDY OF EFFECT OF THE GREEN FEATURE - WING WALLS ON NATURAL VENTILATION IN BUILDINGS

  • Cheuk Ming Mak;Jian Lei Niu;Kai Fat Chan
    • International conference on construction engineering and project management
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    • 2005.10a
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    • pp.814-819
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    • 2005
  • There is growing consciousness of the environmental performance of buildings in Hong Kong. The Buildings Department, the Lands Department and the Planning Department of the Hong Kong Government issued the first of a series of joint practice notes [1] to promote the construction of green and innovative buildings. Green features are architectural features used to mitigate migration of noise and various air-borne pollutants and to moderate the transport of heat, air and transmission of daylight from outside to indoor environment in an advantageous way. This joint practice note sets out the incentives to encourage the industry in Hong Kong to incorporate the use of green features in building development. The use of green features in building design not only improves the environmental quality, but also reduces the consumption of non-renewable energy used in active control of indoor environment. Larger window openings in the walls of a building may provide better natural ventilation. However, it also increases the penetration of direct solar radiation into indoor environment. The use of wing wall, one of the green features, is an alternative to create effective natural ventilation. This paper therefore presents a preliminary numerical study of its ventilation performance using Computational Fluid Dynamics (CFD). The numerical results will be compared with the results of the wind tunnel experiments of Givoni.

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An Output Voltage Balance Control of Grid Connected Inverter by Phase Current Control at Critical Load Unbalanced Condition (계통연계 인버터의 주요 부하 불평형 시 상전류 제어를 통한 부하 상전압 평형 제어)

  • Tae-Hyeon Park;Hag-Wone Kim;Kwan-Yuhl Cho;Joon-Ki Min;Won-Il Choi
    • The Transactions of the Korean Institute of Power Electronics
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    • v.28 no.1
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    • pp.22-29
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    • 2023
  • A grid-connected inverter can be used in grid-connected or stand-alone modes. Generally, a grid-connected inverter operates in a grid-connected mode, but the inverter operates in stand-alone mode if grid faults occur. In the stand-alone mode, the grid-connected inverter must supply electric power to a critical load that needs to receive stable power even though grid faults occur. Generally, three-phase loads are used as critical loads, but a single phase is configured in some cases. In these conditions, the critical load is required to unbalance the load power consumption, which makes the three-phase load voltage unbalancd. This unbalanced voltage problem can cause fatal problems to the three-phase critical loads, and thus must be addressed. Hence, this paper proposes an algorithm to solve this unbalanced voltage problem by the individual phase current control. The proposed method is verified using Psim simulation and experiments.