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Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children

  • Akbulut, Ulas Emre;Kartal, Seyfi;Dogan, Ufuk;Akcali, Gulgun Elif;Kalayci, Serap;Kirci, Hulya
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.3
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    • pp.217-224
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    • 2019
  • Purpose: Various publications on the use of sedation and anesthesia for diagnostic procedures in children have demonstrated that no ideal agent is available. Although propofol has been widely used for sedation during esophagogastroduodenoscopy in children, adverse events including hypoxia and hypotension, are concerns in propofol-based sedation. Propofol is used in combination with other sedatives in order to reduce potential complications. We aimed to analyze whether the administration of midazolam would improve the safety and efficacy of propofol-based sedation in diagnostic esophagogastroduodenoscopies in children. Methods: We retrospectively reviewed the hospital records of children who underwent diagnostic esophagogastroduodenoscopies during a 30-month period. Demographic characteristics, vital signs, medication dosages, induction times, sedation times, recovery times, and any complications observed, were examined. Results: Baseline characteristics did not differ between the midazolam-propofol and propofol alone groups. No differences were observed between the two groups in terms of induction times, sedation times, recovery times, or the proportion of satisfactory endoscopist responses. No major procedural complications, such as cardiac arrest, apnea, or laryngospasm, occurred in any case. However, minor complications developed in 22 patients (10.7%), 17 (16.2%) in the midazolam-propofol group and five (5.0%) in the propofol alone group (p=0.010). Conclusion: The sedation protocol with propofol was safe and efficient. The administration of midazolam provided no additional benefit in propofol-based sedation.

Omega-7 producing alkaliphilic diatom Fistulifera sp. (Bacillariophyceae) from Lake Okeechobee, Florida

  • Berthold, David Erwin;Rosa, Nina de la;Engene, Niclas;Jayachandran, Krish;Gantar, Miroslav;Laughinghouse, Haywood Dail IV;Shetty, Kateel G.
    • ALGAE
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    • v.35 no.1
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    • pp.91-106
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    • 2020
  • Incorporating renewable fuel into practice, especially from algae, is a promising approach in reducing fossil fuel dependency. Algae are an exceptional feedstock since they produce abundant biomass and oils in short timeframes. Algae also produce high-valued lipid products suitable for human nutrition and supplement. Achieving goals of producing algae fuels and high-valued lipids at competitive prices involves further improvement of technology, especially better control over cultivation. Manipulating microalgae cultivation conditions to prevent contamination is essential in addition to promoting optimal growth and lipid yields. Contamination of algal cultures is a major impediment to algae cultivation that can however be mitigated by choosing extremophile microalgae. This work describes the isolation of alkali-tolerant / alkaliphilic microalgae native to South Florida with ideal characteristics for cultivation. For that purpose, water samples from Lake Okeechobee were inoculated into Zarrouk's medium (pH 9-12) and incubated for 35 days. Selection resulted in isolation of three strains that were screened for biomass and lipid accumulation. Two alkali-tolerant algae Chloroidium sp. 154-1 and Chlorella sp. 154-2 were poor lipid accumulators. One of the isolates, the diatom Fistulifera sp. 154-3, was identified as a lipid accumulating, alkaliphilic organism capable of producing 0.233 g L-1 d-1 dry biomass and a lipid content of 20-30% dry weight. Lipid analysis indicated the most abundant fatty acid within Fistulifera sp. was palmitoleic acid (52%), or omega-7, followed by palmitic acid (17%), and then eicosapentanoic acid (15%). 18S rRNA phylogenetic analysis formed a well-supported clade with Fistulifera species.

Study on Dietary Habits of College Women according to the Residence Type in Seoul (일부 서울지역 여대생의 거주형태에 따른 식습관 비교 분석)

  • Park, Jung-Hyun;Jung, Ji-Hye;Kim, Hyun-Sook
    • Journal of the Korean Dietetic Association
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    • v.17 no.4
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    • pp.335-348
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    • 2011
  • This study was designed to compare the dietary habits of women's university students according to residence type. The subjects were 140 females divided into four groups. The first group consisted of students residing at home with their parents (home, n=39), the second group consisted of students residing in a dormitory (dormitory, n=34), the third group consisted of students residing in a boarding house (boarding, n=36), and the fourth group consisted of self-boarding students (self-boarding, n=31). The average age was 21.9 years, and the BMI levels of the groups were $20.8kg/m^2$, $19.6kg/m^2$, $20.5kg/m^2$, and $19.7kg/m^2$, respectively. The 'home' group had higher dietary regularity than the other groups (P<0.05). The boarding group and self-boarding group were more likely to eat out and skip breakfast than the home and dormitory groups (P<0.05). All groups indicated that frequency of snacking was higher than 1 time per day, but there was no significant difference between the groups. The dormitory and boarding groups spent less time consuming meals than the other groups. In conclusion, women's university students show different dietary behaviors according to residence type. Especially, the dormitory, boarding, and self-boarding groups need to improve their dietary habits through high quality education and nutritional support at college cafeterias.

A Qualitative Study on Experiences of Parenthood Among Mothers of Early School-Age Children (학령 초기 자녀를 둔 어머니들의 부모됨 경험에 대한 질적 연구)

  • Doh, Hyun-Sim;Song, Seung-Min;Lee, Woon Kyung;Kim, Min-Jung;Shin, Nana;Kim, Tae Woo
    • Korean Journal of Child Studies
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    • v.37 no.3
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    • pp.147-166
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    • 2016
  • Objective: The purpose of this study was to gain an understanding of parenthood of mothers of early school-age children, with emphasis on cognitive, behavioral, and emotional aspects of parenthood. Methods: Nineteen mothers whose children were 1st and 2nd grade elementary school children participated in this study. Data were collected through individual in-depth interviews. During the interview, mothers were asked to speak freely about their experiences as parents of early-school age children, including parenting beliefs, parenting behaviors, and emotional experiences related to parenting. These interviews were transcribed verbatim and analyzed in a thematic way using MAXQDA. Results: Using qualitative methods, five major themes were emerged: (1) Recognizing the role of parents as a supporter of growth; (2) recognizing parenthood of the present generation that imposes expanded roles to mothers; (3) co-parenting of early school-age children and marital relationship; (4) co-existence of different parenting styles based on specific mother-child interaction situations; (5) experiencing a wide spectrum of emotions including anxiety, guilt, and depression, as well as happiness. Conclusion: This study revealed the unique cognitive, behavioral, and emotional aspects of parenthood experienced by mothers with early school-age children. Results of this study can fill a gap in our understanding of parenthood of mothers when their children entered into the new developmental stage of middle childhood. The results could also be used as a basis for developing parent education and family relationship programs.

A Study on Multicultural Competence of University Students in the Fields of Human Services for the Era of Fusion and Convergence (융복합 시대 휴먼서비스분야 전공대학생의 다문화 역량에 관한 연구)

  • Park, So-Jeong;Bae, Yang-Ja;Park, Sun-Hee;Kim, Sun-Ae
    • Journal of Digital Convergence
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    • v.13 no.11
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    • pp.493-507
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    • 2015
  • This study conducted research on the actual condition of multicultural education in universities and multicultural competence among university students. The overall results are discussed by two sections as follows: The average score of multicultural competence is 3.49, above moderate. The students who rate their multicultural competence high are those who have been abroad, lived in aborad, had foreign friends, or had communicative ability in foreign languages. There were significant differences in multicultural competence among students based on gender and major. Based on the overall results of the study, the several suggestions were made by the researcher as follows: Universities should support students' overseas volunteer program and encourage students to participate in domestic volunteer program for multicultural background groups.

A study on the infant daycare center teacher practicing infant's rights respect in care giving daycare center's daily work (어린이집의 하루일과에서 영아반 보육교사가 실행하는 영아권리존중보육에 관한 연구)

  • Youn, Jin-Ju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.407-417
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    • 2017
  • This study examined the extent to which childcare methods of infant classroom childcare teachers who respect infant rights in the everyday teaching curriculum at day-care centers occurs. To achieve these objectives, a questionnaire survey was conducted on 210 infant classroom childcare teachers who were in charge of the day-care center classrooms located in [G] city of [J] province. The results of the research confirmed that first there were no statistically significant differences when verifying the extent to which childcare methods of infant classroom childcare teachers who respect infant rights in the everyday teaching curriculum at day-care centers according to the final education level, professional experience, age, and education major of the infant classroom childcare teacher. On the other hand, the results confirmed that when analyzing for arrival time for infant classroom childcare instruction at the day-care center and for the time spent taking the infant to and from the bathroom, the infant classroom childcare teachers who had graduated from 2 year colleges showed more respect for infant rights compared to that of infant classroom childcare teachers who had graduated from 4 year universities, and for the arrival time for infant classroom childcare instruction at the day-care center and nap times, the infant classroom childcare teachers who were above 50 years of age showed more respect for infant rights compared to that of infant classroom childcare teachers who were in their 30s and 40s. The results of the research confirmed that there were statistically significant differences for both the age and education major of the infant classroom childcare teachers. When examining each of the sub-factor, the age of the infant classroom childcare teachers, respect for the infant's opinion, respect for individuality, and for information provision, infant classroom childcare teachers older than 50 years of age were shown to exercise a higher level of respect for the infant according to the rule of prioritizing the infant compared to infant classroom childcare teachers in their 30s and 40s, and infant classroom childcare teachers who majored in infant education-related majors exercised a higher level of respect for the infant for respecting freedom and autonomy compared to that of infant classroom childcare teachers who majored in welfare and childcare-related fields. The results of the research confirmed a statistically significant static correlation between the two related variables. Therefore, this suggests that the more childcare methods of infant classroom childcare teachers who respect infant rights in the everyday teaching curriculum at day-care centers, the more childcare methods of infant classroom childcare teachers who respect infant rights occurred according to the rule of prioritizing the infant. These results can be used to establish both quantitatively and qualitatively an excellent and balanced respect for infant rights.

A Strategic Approach to Construction of a Course Module for Innovative Product Design and Development (혁신제품개발 교육과정 개발을 위한 전략수립 방법)

  • Jung, Ki-Hyo;Chang, Jun-Ho;Lee, Won-Sup;Chang, Joon-Ho;You, Hee-cheon;Chang, Soo-Y.;Jun, Chi-Hyuck
    • Journal of Engineering Education Research
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    • v.11 no.3
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    • pp.5-11
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    • 2008
  • Far greater than ever before is the present industrial demand for skilled professionals in innovative product design and development. Yet there is an apparent lack of a sufficient curricular provision for training design professionals in almost all engineering schools. The present study is to propose a systematic procedure for developing a strategy for building an innovative product design curriculum and demonstrate its application. The procedure consists of three major steps: strategic element derivation, task formulation, and task execution roadmap construction. The proposed procedure was applied to develop a modular curriculum (a cluster of several related courses) covering various subjects in relation to innovative product design and development. The procedure seems quite effective and useful for developing a curriculum that is strategically well differentiated based on the unique characteristics of a particular educational institute and its applicability seems not limited to a specific domain.

Mental health and nutritional intake according to sleep duration in adolescents - Based on the 2007-2016 Korea National Health and Nutrition Examination Survey - (청소년들의 수면시간에 따른 정신건강 및 영양섭취 상태 - 국민건강영양조사(2007-2016년)자료를 이용하여 -)

  • Ki, Ye Jin;Kim, Yookyung;Shin, Woo-Kyoung
    • Journal of Korean Home Economics Education Association
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    • v.30 no.4
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    • pp.1-14
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    • 2018
  • The purpose of this study was to examine the relevance of mental health and nutritional intake according to the sleep duration of Korean adolescents. This study was based on data from the 2007-2016 Korea National Health and Nutrition Examination Survey(KNHNES), including 5,489 total subjects (2,795 middle school students, 2,694 high school students). The association between sleep duration and mental health was analyzed using a logistic regression analysis, and the link between sleep duration and nutritional intake was analyzed via a generalized linear model. An analysis of sleep duration showed that middle school students had a higher average sleep duration than high school students (P<0.0001). An analysis of the relationship between sleep duration and mental health showed that middle school students had lower rates of stress perception (P<0.0001) and suicidal ideation (P=0.0005) as their sleep duration increased. High school students had 53% less suicidal ideation in the group getting 6-7 hours compared to the group getting less than 6 hours, and 37% less suicidal ideation than the group getting 7-8 hours. The link between sleep duration and stress perception was statistically significant among both middle and high school students (P for interaction=0.02). An analysis of the daily intake of major nutrients according to sleep hours found high intake of vitamin C in groups where high school students slept more than nine hours (P=0.003). The state of nutritional intake according to higher sleep duration showed statistically significant differences between higher intake of phosphorus, riboflavin, niacin, and vitamin C in Nutrient Adequacy Ratio for high school students. In conclusion, adolescents' sleep duration is associated with stress perception, suicidal ideation and nutritional intake. Therefore, this study emphasizes the mental importance of adolescent sleep and can be used as a basis for nutrition education.

Patterns of Reasoning Regarding the Korean Traditional Interpretation of Planet Occultation by the Moon: A Comparative Study among Four Groups ('월엄범오위'의 사례에 나타난 전통적 천문관에 관한 판단 유형: 4개 집단간 비교 연구)

  • Oh, Phil-Seok;Choe, Seung-Urn
    • Journal of the Korean earth science society
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    • v.21 no.4
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    • pp.398-407
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    • 2000
  • We investigated people's patterns of reasoning regarding the Korean traditional interpretation of Planet Occultation by the Moon. A questionnaire survey was administered to the sample which consisted of 632 participants: middle school students(n=164), high school students(n=157), university students(n=172), and the public(n=139). It was revealed that 15.7% of the participants agreed, 38.1% disagreed, and 46.2% were neutral to the traditional interpretation. A comparatively large portion of the university students made a scientifically correct judgement by disagreeing with the traditional interpretation. On the other hand, a relatively small proportion of the middle school students disagreed. Participants' views of nature and views of science were the major reasons for making their judgements. Most participants were fixed with similar views to the Korean traditional view of nature. Most of the participants valued using more extensive evidence and experimental proofs in science. High school and university students considered their metaphysical beliefs, such as view of nature and view of science, more important than other groups did. In contrast to this, middle school students and the public depended more strongly on their personal experiences. Participants' social experiences and their scientific knowledge were also important reasons for making their judgement. However the differences in their scientific knowledge seemed to exert different influences on their reasoning. The results of this study show differences in how an individual thinks as well as differences between communities. Thus, science education and research considering multicultural settings are needed. In addition, science educators and researchers should pay attention to pupils' metaphysical beliefs such as their views of nature and views of science.

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GC-MS Analysis of Volatile Constituents from Acanthopanax sessiliflorus (오갈피나무의 정유성분 GC-MS 분석)

  • Lim, Soon-Sung;Lee, Yeon-Sil;Lee, Sul-Lim;Kim, Jong-Kee;Cho, Seon-Haeng;Shin, Kuk-Hyun;Lee, Sang-Hyun
    • Korean Journal of Pharmacognosy
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    • v.39 no.1
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    • pp.7-18
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    • 2008
  • The chemical composition of the volatile constituents from the leaves, stems, and roots of Acanthopanax sessiliforus growing wild in Mt. Deok-Yu was determined by GC and GC-MS spectrometric analysis with the aid of NBS, Wiley Library and RI indice searches. The major constituents identified were ${\delta}-3-carene$ (7.24%), limonene (8.10%), ${\beta}-thujene$ (17.85%), trans-bicyclic hydrocarbon (13.35%) and ${\delta}-cadinene$ (4.28%) in the leaves from one year-grown plants, tricyclene (7.21%), ${\beta}-myrcene$ (7.62%), limonene (10.23%), ${\beta}-thujene$ (15.61%) and dihydroedulan I (6.12%) in the leaves from three years-grown plants, ${\delta}-3-carene$ (4.96%), limonene (5.93%), ${\beta}-phellandrene$ (17.31%) and naphthalene (7.79%) in the stems from one year-grown plants, ${\alpha}-pinene$ (5.21%), limonene (5.12%) and ${\beta}-phellandrene$ (9.82%) in the stems from three years-grown plants, ${\alpha}-pinene$ (12.73%), ${\beta}-pinene$ (11.16%), ${\delta}-3-carene$ (6.16%) and ${\gamma}-cadinene$ (23.39%) in the roots from one year-grown plants, and ${\alpha}-pinene$ (17.25%), ${\beta}-pinene$ (9.35%), ${\delta}-3-carene$ (7.26%) and ${\gamma}-cadinene$ (17.95%) in the roots from three years-grown plants.