• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6663-6667
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• 2013

Purpose: The current research was conducted to investigate the efficacy and safety of pemetrexed given continuously as a basement agent for first-, second- to third line chemotherapy of patients with metastatic lung adenocarcinoma. Patients and Methods: Patients with metastatic lung adenocarcinoma who were diagnosed in Jiangsu Cancer Hospital and Research Insitute, were enrolled. All received pemetrexed 500 $mg/m^2$ (intravenous; on day 1), and another chemotherapieutic agent every 3 weeks until disease progression, or intolerable toxicity. Then the patients were changed to a second line chemotherapy that was still based on pemetrexed 500 $mg/m^2$ and another chemotherapeutic agent differing from the first line example, until disease progression, or intolerable toxicity. When third line chemotherapy was needed, pemetrexed 500 $mg/m^2$ and another new chemotherapeutic agent were combined until disease progression. Evaluation of efficacy was conducted after two cycles of chemotherapy using the Response Evaluation Criteria for Solid Tumors. Toxicity was recorded according to NCI Criteria for Adverse Events version 3.0. Results: From January 2010 to September 2013, 15 patients were enrolled. Their median age was 56 years (range 43 to 77 years). Eight patients were male and 7 female. Five patients (33.3%) achieved PR, while 6 patients (40.0%) remained stable, no CR on first line; and 1 PR (7.7%), 5 stable (38.5%) were recorded when pemetrexed was ordered in second line; 5 patients (41.7%) were stable after pemetrexed was combined in third line; no complete response was observed. Main side effects were grade 1 to 2 neutrophil suppression and thrombocytopenia. Other toxicities included elevated transaminase and oral mucositis, but no treatment related death occurred. Conclusions: Pemetrexed continuously as a basement agent from first-, second- to third line chemotherapy is mildly effective in treating patients with metastatic lung adenocarcinoma with tolerable toxicity.

• Korean Chemical Engineering Research
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• 제46권2호
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• pp.369-375
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• 2008

생태산업단지의 주요 목표인 무배출(zero-emission)을 달성하기 위해서는, 기업간의 효과적인 용수 재이용망의 구축이 요구된다. 다양한 서브시스템과 의사결정과정을 포함한 복잡한 망 구조를 이루기 때문에 생기는 모델링 부분에서의 문제점을 해결하기 위하여, 본 연구에서는 새로운 모델링 기법인 에이전트기반 모델링(agent based modeling, ABM)을 도입하였다. 에이전트기반 모델링 기법을 이용해 물질교환망 내의 기업을 에이전트화 하고 이를 토대로 전체 시스템을 모사하는 방법론을 제시하였으며, 이를 이용해 실제 산업단지 내 기업에 대한 간단한 용수교환망 설계 모델을 구축하였다. 에이전트기반 모델에 기초한 용수재이용망은 용수공급에서 35% 감소를 보이며 폐수 배출량은 약 50%가 감소하였다. 실제 산업단지 모델링 결과 에이전트기반 모델은 시스템 변동시에도 전체 시스템을 수정할 필요가 없으며, 시스템이 확장하는 경우에도 그 적용이 용이하기 때문에 생태산업단지와 같은 복잡한 시스템의 모델링과 설계시 유용한 기술로 사용될 수 있음을 보였다.

• Elastomers and Composites
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• 제54권2호
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• pp.118-122
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• 2019

Four different polymer compounds were manufactured to make cable sheaths for the shipping industry. Two kinds of ethylene vinyl acetate (EVA) as the main matrix polymers and EVA-grafted maleic anhydride (EVA-g-MAH) as the coupling agent were selected for compounding with fire retardant, crosslinking agent, filler, plasticizer, and other additives. The properties of the four compounded materials were investigated with different contents of the fire retardant, silanecoated magnesium dihydroxide (S-MDH). In the rheology evaluation, the $t_{60}$ and ${\Delta}T$ values increased with increasing S-MDH contents. On the other hand, the tensile strength decreased with increasing S-MDH content due to a relative decrease in binder polymers. With increasing S-MDH content, fire resistance increased, but cold resistance showed no obvious enhancement due to the polar effect of vinyl acetate in EVA.

• 한국콘텐츠학회논문지
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• 제16권8호
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• pp.517-528
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• 2016

이 연구는 이미 실생활에서 사용되고 있으나 이에 대한 실증적 사용자 경험 조사가 부족한 사물인터넷 기반 제품에 대한 새로운 사용자 경험 방법론을 탐색해보고자 진행되었다. 지금까지의 사용자 경험에 대한 연구가 주로 설문이나 관찰 방법 등을 통해 이루어져 온 것과 달리 본 연구에서는 사물인터넷 기반 제품 중 지능형 에이전트인 아마존 에코(Echo)를 대상으로 사용자들의 온라인 리뷰를 분석하는 빅데이터 분석 기법을 활용하여 사용자 경험을 살펴보았다. 토픽 모델링 분석 결과, 에코의 기능, 음성 인터랙션, 지속적인 기능 개선과 관련된 사용 경험 요인들이 도출되었다. 또한 회귀분석결과 지속적인 기능 개선이 만족도에 가장 큰 영향을 미치는 것으로 나타났다. 연구의 의의는 사용자 경험을 제고할 수 있는 지능형 사물인터넷 제품 연구방법으로서 빅데이터 분석방법론 활용 가능성을 제시한 점이다.

• 한국정보시스템학회지:정보시스템연구
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• 제31권2호
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• pp.137-158
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• 2022

Purpose As artificial intelligence voice agents (AIVA) have been widely adopted in services, diverse forms of their voices, which are the main interface with users, have been experimented. The purpose of this study is to examine how users evaluate vocal characteristics (gender, voice pitch, and voice pace) of AIVA, depending on prior research on human voice attractiveness. Design/methodology/approach This study employed an experimental survey which 516 participated in. Each participant was randomly assigned into one of eight situations (e.g., male - higher pitch - faster pace) and listened a AIVA voice sample, which introduce weather information. Next, a participant answered three consequence factors (attractiveness, trust, and anthropomorphism). Findings The results reveal that female voices of AIVA were perceived as more attractive and trustworthy than male voices. As far as voice pitch goes, while lower-pitch voices were preferred in female voices, higher-pitch voices were preferred in male voices. Finally, faster voices of AIVA were more attractive than slower voices.

• 한국군사과학기술학회지
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• 제26권4호
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• pp.361-370
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• 2023

Swarm has recently become a critical component of offensive and defensive systems. Multi-agent reinforcement learning(MARL) empowers swarm systems to handle a wide range of scenarios. However, the main challenge lies in MARL's scalability issue - as the number of agents increases, the performance of the learning decreases. In this study, transfer learning is applied to advanced MARL algorithm to resolve the scalability issue. Validation results show that the training efficiency has significantly improved, reducing computational time by 31 %.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제18권6호
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• pp.1431-1448
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• 2024

Complexity science is a new stage in the development of systems science that is the frontier areas of contemporary scientific development. Complexity science takes complex systems as the research object, which has attracted widespread attention from researchers in the fields of economy, control, management, and society. In recent years, with the rapid development of science and technology and people's deepening understanding for the theory of complex systems, the systems are no longer an object with a single function, but the systems are composed of multiple individuals with autonomous capabilities through cooperative and cooperation, namely multi-agent system (MAS). Currently, MAS is one of the main models for studying such complex systems. The intelligent control is to break the traditional multi-agent fault-tolerant control (FTC) concept and produce a new type of compensation mechanism. In this paper, the applications of fault-tolerant control methods for MASs are presented, and a discussion is given about development and challenges in this field.

• 한국시뮬레이션학회논문지
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• 제17권2호
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• pp.83-90
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• 2008

본 연구에서는 분산인공지능의 한 영역인 블랙보드구조를 통한 침입탐지 에이전트간의 연동 방법에 대해서 소개한다. 연동을 위해서 블랙보드를 사용한 시스템은 쉽게 확장이 가능하여 새로운 에이전트를 추가하기 용이하고, 블랙보드의 레벨을 수정하기 용이하다. 대상시스템에 시뮬레이션을 수행한다. 본 연구에서는 정책기반 네트워크를 사용하여 침입 탐지의 성능을 높이고자 하는데, 이를 적용함으로써 false positive를 줄일 수 있다. 정책기반네트워크를 통해 침입탐지 에이전트들이 서로 연동함으로써 성능의 향상을 이룬다는 것을 기존의 시스템과 비교함으로써 증명한다. 본 연구의 결과는 다양한 보안 정책을 적용하는데 사용될 수 있다.

• 한국산업정보학회:학술대회논문집
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• 한국산업정보학회 1999년도 춘계학술대회 발표논문집
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• pp.154-162
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• 1999

This paper introduces the research and development of automatic generation technology to develop the character agent. The R&D of this technology includes three major elements-body model generation, automatic motion generation and synthetic human generation. Main areas of application would be cyber space- 3D game, animation, virtual shopping, on line chatting, virtual education system, simulation and security system.

• 멤브레인
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• 제28권3호
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• pp.205-213
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• 2018

본 연구에서는 가교막을 poly(2,6-dimethyl-1,4-phenylene oxide)(PPO)에 브롬화반응을 통해 제조한 Br-PPO를 주사슬로 성공적으로 제조하였고, 키토산과 4차암모늄이 포함된 키토산을 가교제로 사용하였다. 제조된 가교막은 트리메틸아민 용액에 함침하여 후처리를 진행하였다. 그리고 가교도는 가교제 비율을 이용하여 조절하였다. 이렇게 제조된 A-PPO + chitosan 가교막과 A-PPO + QA-chitosan 가교막의 이온교환막으로써의 가능성을 여러 특성평가로 확인하였다. Chitosan을 사용한 가교막보다 QA-chitosan을 사용한 가교막이 가교가 더 잘 이루어졌으며, QA-chitosan의 함량이 증가할수록 이온교환용량이 1.18 meq/g에서 1.53 meq/g까지 증가하는 경향, 함수율이 21.6%에서 42.2%까지 증가하는 경향을 나타내었다.