• Title/Summary/Keyword: magnetic alignment

Search Result 111, Processing Time 0.025 seconds

Molecular interaction between SH3 domain of PACSIN2 and proline-rich motifs of Cobll1

  • Yoo, Hee-Seop;Seok, Seung-Hyeon;Kim, Ha-Neul;Kim, Ji-Hun;Seo, Min-Duk
    • Journal of the Korean Magnetic Resonance Society
    • /
    • v.26 no.3
    • /
    • pp.34-39
    • /
    • 2022
  • The SH3 domain found within a variety of proteins is comprised of generally 60 residues, and participated in protein-protein interactions with proline-rich motifs. Cobll1 was identified as a distinct molecular marker associated with CML progression, and PACSIN2 was discovered a novel Cobll1 binding partner through direct interaction between a SH3 domain of PACSIN2 and three proline-rich motifs of Cobll1. To understand the structural basis of interactions between PACSIN2 and Cobll1, backbone assignments of PACSIN2 SH3 domain were performed. Furthermore, three proline-rich peptides of Cobll1 were titrated to 15N-labeled PACSIN2 SH3 domain in various ratios. Our chemical shift changes data and conserved SH3 sequence alignment will be helpful to analyze fundamental molecular basis related to the interaction between PACSIN2 and Cobll1.

The Predictable Factors of the Postoperative Kyphotic Change of Sagittal Alignment of the Cervical Spine after the Laminoplasty

  • Lee, Jun Seok;Son, Dong Wuk;Lee, Su Hun;Kim, Dong Ha;Lee, Sang Weon;Song, Geun Sung
    • Journal of Korean Neurosurgical Society
    • /
    • v.60 no.5
    • /
    • pp.577-583
    • /
    • 2017
  • Objective : Laminoplasty is an effective surgical method for treating cervical degenerative disease. However, postoperative complications such as kyphosis, restriction of neck motion, and instability are often reported. Despite sufficient preoperative lordosis, this procedure often aggravates the lordotic curve of the cervical spine and straightens cervical alignment. Hence, it is important to examine preoperative risk factors associated with postoperative kyphotic alignment changes. Our study aimed to investigate preoperative radiologic parameters associated with kyphotic deformity post laminoplasty. Methods : We retrospectively reviewed the medical records of 49 patients who underwent open door laminoplasty for cervical spondylotic myelopathy (CSM) or ossification of the posterior longitudinal ligament (OPLL) at Pusan National University Yangsan Hospital between January 2011 and December 2015. Inclusion criteria were as follows : 1) preoperative diagnosis of OPLL or CSM, 2) no previous history of cervical spinal surgery, cervical trauma, tumor, or infection, 3) minimum of one-year follow-up post laminoplasty with proper radiologic examinations performed in outpatient clinics, and 4) cases showing C7 and T1 vertebral body in the preoperative cervical sagittal plane. The radiologic parameters examined included C2-C7 Cobb angles, T1 slope, C2-C7 sagittal vertical axis (SVA), range of motion (ROM) from C2-C7, segmental instability, and T2 signal change observed on magnetic resonance imaging (MRI). Clinical factors examined included preoperative modified Japanese Orthopedic Association scores, disease classification, duration of symptoms, and the range of operation levels. Results : Mean preoperative sagittal alignment was $13.01^{\circ}$ lordotic; $6.94^{\circ}$ lordotic postoperatively. Percentage of postoperative kyphosis was 80%. Patients were subdivided into two groups according to postoperative Cobb angle change; a control group (n=22) and kyphotic group (n=27). The kyphotic group consisted of patients with more than $5^{\circ}$ kyphotic angle change postoperatively. There were no differences in age, sex, C2-C7 Cobb angle, T1 slope, C2-C7 SVA, ROM from C2-C7, segmental instability, or T2 signal change. Multiple regression analysis revealed T1 slope had a strong relationship with postoperative cervical kyphosis. Likewise, correlation analysis revealed there was a statistical significance between T1 slope and postoperative Cobb angle change (p=0.035), and that there was a statistically significant relationship between T1 slope and C2-C7 SVA (p=0.001). Patients with higher preoperative T1 slope demonstrated loss of lordotic curvature postoperatively. Conclusion : Laminoplasty has a high probability of aggravating sagittal balance of the cervical spine. T1 slope is a good predictor of postoperative kyphotic changes of the cervical spine. Similarly, T1 slope is strongly correlated with C2-C7 SVA.

Improvement of Magnetic Properties of Nd-Fe-B Type Sintered Magnet (Nd-Fe-B계 소결자석의 자기적특성 향상 연구)

  • Kim, Yoon-B.;Jung, W.S.;Jeung, W.Y.
    • Journal of the Korean Magnetics Society
    • /
    • v.12 no.2
    • /
    • pp.57-63
    • /
    • 2002
  • In order to increase the magnetic properties of a Nd-Fe-B sintered magnet, the general factors including particle size and its distribution, volume fraction of Nd$_2$Fe$_{14}$B phase, degree of alignment of Nd$_2$Fe$_{14}$B grain, oxygen content and grain size etc. should be optimized by controlling the composition of Nd-Fe-B alloy as well as the manufacturing process. In this study, fabrication of the Nd-Fe-B sintered magnet was carried out in a laboratory scale by controlling the composition of Nd-Fe-B alloy and the manufacturing process. The optimum milling condition was found by investigating the milling media, milling time and ball size. The addition of FeGa was effective to increase the coercivity of the Nd-Fe-B sintered magnet. A remanence of 14.4 kG, a coercivity of 9.4 kOe and a maximum energy product of 47 MGOe were obtained from the sintered magnet.

Polyvilylidenefluoride-based Nanocomposite Films Induced-by Exfoliated Boron Nitride Nanosheets with Controlled Orientation

  • Cho, Hong-Baek;Nakayama, Tadachika;Jeong, DaeYong;Tanaka, Satoshi;Suematsu, Hisayuki;Niihara, Koichi;Choa, Yong-Ho
    • Composites Research
    • /
    • v.28 no.5
    • /
    • pp.270-276
    • /
    • 2015
  • Polyvinylidene fluoride (PVDF)-based nanocomposites are fabricated by incorporation of boron nitride (BN) nanosheets with anisotropic orientation for a potential high thermal conducting ferroelectric materials. The PVDF is dissolved in dimethylformamide (DMF) and homogeneously mixed with exfoliated BN nanosheets, which is then cast into a polyimide film under application of high magnetic fields (0.45~10 T), where the direction of the filler alignment was controlled. The BN nanosheets are exfoliated by a mixed way of solvothermal method and ultrasonication prior to incorporation into the PVDF-based polymer suspension. X-ray diffraction, scanning electron microscope and thermal diffusivity are measured for the characterization of the polymer nanocomposites. Analysis shows that BN nanosheets are exfoliated into the fewer layers, whose basal planes are oriented either perpendicular or parallel to the composite surfaces without necessitating the surface modification induced by high magnetic fields. Moreover, the nanocomposites show a dramatic thermal diffusivity enhancement of 1056% by BN nanosheets with perpendicular orientation in comparison with the pristine PVDF at 10 vol % of BN, which relies on the degree of filler orientation. The mechanism for the magnetic field-induced orientation of BN and enhancement of thermal property of PVDF-based composites by the BN assembly are elucidated.

MICROMAGNETISM OF HARD AND SOFT MAGNETIC MATERIALS

  • Kronmuller, Helmut
    • Journal of the Korean Magnetics Society
    • /
    • v.5 no.5
    • /
    • pp.366-371
    • /
    • 1995
  • High performance magnetic materials are characterized by the combination of outstanding magnetic properties and optimized microstructures, e.g., nanocrystalline composites of multilayers and small particle systems. The characteristic parameters of the hysteresis loops of these materials vary over more than a factor of $10^{6}$ with optimum values for the coercive field of several Tesla and permeabilities of $10^{6}$. Within the framework of the computational micromagnetism (nanomagnetism) using the finite element method the upper and lower bounds of the coercive field of different types of grain ensembles and multilayers have been determined. For the case of nanocrystalline composites the role of grain size, exchange and dipolar coupling between grains and the degree of grain alignment will be discusses in detail. It is shown that the largest coercivities are obtained for exchange decoupled grains, whereas remanence enhancing requires exchange coupled grains below 20 nm. For composite permanent magnets based on $Nd_{2}Fe_{14}B$ with an amount of ~ 50% soft $\alpha$-Fe-phase coercivities of ${\mu}_{0}H_{c}=0.75\;T$, a remanence of 1.5 T and an energy product of $400\;kJ/m^{3}$ is expected. In nanocrystalline systems the temperature dependence of the coercivity is well described by the relation ${\mu}_{0}H_{c}=(2\;K_{1}/M_{s}){\alpha}-N_{eff}{\mu}_{0}M_{s}$, where the microstructural parameters $\alpha$ and $N_{eff}$ take care of the short-range perturbations of the anisotropy and $N_{eff}$ is related to the long-range dipolar interactions. $N_{eff}$ is found to follow a logarithmic grain size size dependence ${\mu}_{0}H_{c}=(2\;K_{1}/M_{s}){\alpha}-N_{eff}(\beta1nD){\mu}_{0}M_{s}$. Several trends how to achieve the ideal situation $\alpha$->1 and $N_{eff}$->1->0 will be discussed.

  • PDF

A Linear Motor Using a Magnetostrictive Actuator (자기변형 엑츄에이터를 이용한 선형모터)

  • Park Y.W.;Seok Y.T.
    • Proceedings of the Korean Society of Precision Engineering Conference
    • /
    • 2005.06a
    • /
    • pp.1841-1844
    • /
    • 2005
  • A linear motor makes a long stroke by accumulating short steps, which is based on the quasistatic deformation of a magnetostrictive material in a magnetic field. It's also called as inchworm effect. The application areas of linear motors are an adaptive and active optics, X-Y positioning, precision alignment, etc. It is found that control of the frequency and current inputs are all that is necessary to control the speed handling ability of the linear motor. In inchworm mode, linear speeds of up to $500{\mu}m/s$ are achieved resulting from the accumulation of $25{\mu}m$ steps at 1.4A.

  • PDF

Technology of the End Cap Laser Welding for Irradiation Fuel Rods (조사연료봉 봉단마개의 레이저용접기술)

  • 김수성;이정원;고진현;이영호
    • Journal of Welding and Joining
    • /
    • v.21 no.6
    • /
    • pp.20-25
    • /
    • 2003
  • Various welding methods such as Gas Tungsten Arc Welding(GTAW), magnetic force electrical resistance welding and Laser Beam Welding(LBW) are now available for end cap closure of nuclear fuel rods. Even though the resistance and GTA welding processes are widely used in manufacturing commercial fuel rods, they can not be recommended for the remote seal welding of fuel rods in the hot cell Facility due to the complexity of the electrode alignment, the difficulty in replacing parts in a remote manner and the large heat input for the thin sheath. Therefore, the Nd:YAG laser system using optical fiber transmission was selected for the end cap welding of irradiation fuel rods in the hot cell. The remote laser welding apparatus in the hot cell Facility was developed using a pulsed Nd:YAG laser of 500 watt average power with an optical fiber transmission. The weldment quality such as microstructure and mechanical strength was satisfactory. The optimum conditions of laser welding for encapsulating irradiation fuel rods in the hot cell were obtained.

Formation of biaxial-texture of Ni substrates for deposition of YBCO superconductor by electrodeposition

  • Lee, Kyu-Hwan;Yoo, Jai-Moo;Chung, Hyung-Sik
    • 한국초전도학회:학술대회논문집
    • /
    • v.10
    • /
    • pp.289-292
    • /
    • 2000
  • In order to evade the patent of Oak Ridge National Laboratory (RABiTS process) and search for more economical process, a new process for producing the biaxially textured Ni tape by electrodeposition has been investigated. Electrodeposition was performed in the modified Watts bath. The crystal orientations of electrodeposited Ni were analysed by X-ray pole figure, ${\phi}$-scan and ${\omega}$-scan. The electrodeposited Ni tape showed cube texture with good out-of plane(< 8${\circ}$) and in-plane alignment(< 20${\circ}$).

  • PDF

Dynamic Analysis of the Contact-free Surface Actuator (비접촉식 평면구동기의 동특성해석)

  • 이상헌;백윤수
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.13 no.9
    • /
    • pp.663-670
    • /
    • 2003
  • As the micro-technologies in the high precision manufacturing processes are developed, the demand for micro actuating device is increasing. But, it is difficult to achieve high resolution and wide operating range simultaneously with the conventional actuating systems which are contacting and type of dual servo system. So, the contact-free surface actuators whose movers are suspended or levitated were proposed. These systems can be applied to high precision stages and alignment apparatuses. The suspended mover can be assumed to be rigid body, but the mover is a structure in this study, therefore the vibration caused during the operating process has a serious adverse effect on the performance and it is very important to identify the vibrational characteristics. In this paper, a contact-free surface actuator is modeled in finite element method and updated by using the experimental modal data. Finally, the static and dynamic characteristics of the finite element model are predicted and then discussed.

A Novel Tensile Specimen and Test Machine for Mechanical Properties of MEMS Materials (MEMS 소재의 기계적 특성 평가를 위한 인장형 시편 및 시험기 제작)

  • Park, Jun-Hyub;Kim, Chung-Youb;Lee, Chang-Seun;Choa, Sung-Hoon;Song, Ji-Ho
    • Proceedings of the KSME Conference
    • /
    • 2004.04a
    • /
    • pp.258-263
    • /
    • 2004
  • Mechanical property evaluation of micrometer-sized structures is necessary to help design reliable microelectromechanical systems(MEMS) devices. Most material properties are known to exhibit dependence on specimen size and such properties of microscale structures are not well characterized. This paper describes techniques developed for tensile testing of materials used in MEMS. Epi-polycrystalline silicon is currently the most widely used material, and its tensile strength has been measured as 1.52GPa. We have developed an uniaxial testing machine for testing microscale specimen using electro-magnetic actuator. The field magnet and the moving coil taken from an audio-speaker were utilized as the components of the actuator. Structure of specimen was designed and manufactured for easy handling and alignment. In addition to the static tensile tests, new techniques and procedures for measuring strength are described.

  • PDF