• 제목/요약/키워드: m-family

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Anti-Inflammatory Role of TAM Family of Receptor Tyrosine Kinases Via Modulating Macrophage Function

  • Lee, Chang-Hee;Chun, Taehoon
    • Molecules and Cells
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    • 제42권1호
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    • pp.1-7
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    • 2019
  • Macrophage is an important innate immune cell that not only initiates inflammatory responses, but also functions in tissue repair and anti-inflammatory responses. Regulating macrophage activity is thus critical to maintain immune homeostasis. Tyro3, Axl, and Mer are integral membrane proteins that constitute TAM family of receptor tyrosine kinases (RTKs). Growing evidence indicates that TAM family receptors play an important role in anti-inflammatory responses through modulating the function of macrophages. First, macrophages can recognize apoptotic bodies through interaction between TAM family receptors expressed on macrophages and their ligands attached to apoptotic bodies. Without TAM signaling, macrophages cannot clear up apoptotic cells, leading to broad inflammation due to over-activation of immune cells. Second, TAM signaling can prevent chronic activation of macrophages by attenuating inflammatory pathways through particular pattern recognition receptors and cytokine receptors. Third, TAM signaling can induce autophagy which is an important mechanism to inhibit NLRP3 inflammasome activation in macrophages. Fourth, TAM signaling can inhibit polarization of M1 macrophages. In this review, we will focus on mechanisms involved in how TAM family of RTKs can modulate function of macrophage associated with anti-inflammatory responses described above. We will also discuss several human diseases related to TAM signaling and potential therapeutic strategies of targeting TAM signaling.

노년기 부부의 사회활동 참여수준이 부부관계 만족도에 미치는 영향에 대한 우울감의 매개효과: APIMeM 모형을 활용하여 (The Mediation Effects of Depressive Symptoms on the Association between Social Activity Participation and Marital Satisfaction among Couples in Later Life: Using APIMeM Modeling)

  • 김율리;주수산나;이예슬;김현경
    • Human Ecology Research
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    • 제60권3호
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    • pp.471-481
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    • 2022
  • This study aimed at examining the mediation effects of depressive symptoms on the association between social activity participation and marital satisfaction among couples in later life. The study included 1,196 married couples aged 65 or above who participated in the 7th Korean Longitudinal Study of Aging in 2018. The study variables were husbands' and wives' social activity participation, marital satisfaction, and depressive symptoms. Covariates were individual age, education level, subjective health, couples' household income, and number of children. The Actor-Partner Interdependence Mediation Model (APIMeM) and bootstrapping techniques were used to test the significance of the mediating impacts of depressive symptoms based on the dyadic data structure. The results showed that for both husbands and wives, active participation in social activities had significant effects on increasing marital satisfaction through lowering depressive symptoms. However, only the participation of husbands in social activities was positively associated with their own marital satisfaction by reducing their own and their partner's depressive symptoms. These findings suggest that the active social participation of individuals salient for promoting the quality of marital relationships in later life, particularly for preventing their own and their spouse's depressive symptoms.

두 개의 m-수열에 의해 생성된 새로운 비선형 이진수열군 (A New Family of Nonlinear Binary Sequences Generated by Two m-Sequences)

  • 최언숙;조성진;김한두;권숙희;권민정;김진경
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2012년도 춘계학술대회
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    • pp.228-231
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    • 2012
  • $n=2k$이고, $2s$$k$의 약수이며 홀수인 $i$에 대하여 주기가 $2^n-1$$m$-수열과 새로운 decimation $d=2^{k-1}(2^{s+1}-2^k+2^{k(i+1)}-2^{ki}-1)/(2^s-1)$인에 의해 생성된 수열의 합으로 생성된 새로운 이진수열군에 대하여 그 상관관계를 분석한다. 제안된 수열은 Rosendahl의 수열과 Dobbertin의 수열을 포함하는 확장된 수열이다.

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대형 공동주택 거실 조명환경과 행위별 조명사용에 관한 조사연구 (Investigations on Lighting Environment of Living Room and Lighting Use According to the Behavior in Large Apartment Houses)

  • 김현지;김훈
    • 조명전기설비학회논문지
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    • 제26권3호
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    • pp.1-8
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    • 2012
  • This study investigated current status of lighting environment, residents' awareness of lighting and lighting use according to behavior in the living room of apartment to determine current lighting trends and their related problems. The living rooms of newly-built apartment units(133~165[$m^2$] and larger than 166[$m^2$] within the past five years) were examined. The results are summarized as follows. 1. Resident satisfaction with current living room lighting was the highest in 'illumination' and the lowest was 'energy savings' regardless of the size of living room. 2. This kind of ceiling lighting layout, 133~165[$m^2$] unit used central lighting and larger than 166[$m^2$] units used central lighting and cove lighting. Regarding light sources, 133~165[$m^2$] linear FL, halogen, larger than 166[$m^2$] bulb-type FL are widely used. LED are now being found in the living room corridor and kitchen walls of newly-built apartment houses. 3. Watching TV and reading books were commonly behaved in the living room. Conversations between family, having desserts, resting, housekeeping, and entertaining were usually done weekdays, while having desserts and conversations between family were done weekends. Use of lighting as main behaviors is properly and differently required due to the distinct uses of lighting as residents' behaviors or their life style.

FEED AND FODDER AVAILABILITY IN THE PABNA MILK SHED AREA, BANGLADESH

  • Islam, M.;Sarker, N.R.;Islam, M.M.;Yasmin, L.
    • Asian-Australasian Journal of Animal Sciences
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    • 제8권3호
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    • pp.301-305
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    • 1995
  • The study was conducted at village level in Pabna milkshed areas of Bangladesh to asses the existing feed and fodder sources of cattle. The results showed that the overall number of cattle per farm family was 7.17 and chicken represents highest number (15.57) per farm family in this area. The results also indicated that during monsoon season the bathan is planted with Vigna mungo and Lathyrus sativus and average grazing hours per day varied from 1.1 in October to 5.6 in February. In Summer, they were offered naturally grown Cynodon dactylon with supplementary feeding of rice straw. The study further showed that the highest (65.7%) feed scarcity was found during mid April to mid May followed by mid June. The cultivation of Vigna mungo was highest (76.71%) compared to Lathyrus sativus by the farmers in the bathan areas. The major constraint to cattle production is the scarcity of quality feed during mid October to mid November.

Taxonomy of Black Coral Family Myriopathidae (Anthozoa: Antipatharia) from Korea

  • Moon, Hye-Won;Song, Jun-Im
    • Animal Systematics, Evolution and Diversity
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    • 제24권3호
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    • pp.251-263
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    • 2008
  • Eight species and four genera belonging to two families of antipatharians have been reported in Korea. In the present study, the major specimens were collected from the coastal areas of Jejudo Island from 2005 to 2006, and the other ones which have been deposited in the Natural History Museum and the Department of Life Science, Ewha Womans University during the period from 1965 to 2004 were reexamined. As a result of this work, four species, Myriopathes bifaria, M. stechowi, M. ulex and Plumapathes pennacea are new to Korean antipatharian fauna. In this study, total six species including previously recorded species of the family Myriopathidae were described. And the distribution range of Myriopathes lata was turned out to be expanded from southwestern sea to the eastern sea, up to Ulleungdo Is. of Korea. Especially, the sexuality and the gonadal stage of M. lata which are collected during their reproduction period were also determined by means of histological analysis.

공동주택단지 주거 서비스에 대한 거주자들의 태도에 관한 연구 (A study on the Residents' Needs for the Residential Services of Multi-family Housing)

  • 강혜경;조성희
    • 한국주거학회:학술대회논문집
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    • 한국주거학회 2003년도 정기총회 및 추계학술대회
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    • pp.201-206
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    • 2003
  • The purpose of this study is to find out the residents' needs fer the residential services according to residents' characteristics in multi-family housing. The results of this study are as follows 1) It was found that the 22 elements were selected as the residential services and they were categorized by 5 factors for the analysis 2) The ranked favorable needs of residential-services were the garbage separation(M=3.97), the apartment complex management (M=3.89), the parking management(M=3.88) etc. orderly. 3) As to there results analyzing the needs for the residential services, it was found that there were differences in needs according to the residents' characteristics. Therefore, this study emphasized on the necessity of the planning to classify the residential services according to the residents' characteristics.

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A M-TYPE RISK MODEL WITH MARKOV-MODULATED PREMIUM RATE

  • Yu, Wen-Guang
    • Journal of applied mathematics & informatics
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    • 제27권5_6호
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    • pp.1033-1047
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    • 2009
  • In this paper, we consider a m-type risk model with Markov-modulated premium rate. A integral equation for the conditional ruin probability is obtained. A recursive inequality for the ruin probability with the stationary initial distribution and the upper bound for the ruin probability with no initial reserve are given. A system of Laplace transforms of non-ruin probabilities, given the initial environment state, is established from a system of integro-differential equations. In the two-state model, explicit formulas for non-ruin probabilities are obtained when the initial reserve is zero or when both claim size distributions belong to the $K_n$-family, n $\in$ $N^+$ One example is given with claim sizes that have exponential distributions.

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Fisher Information and the Kullback-Leibler Distance in Concomitants of Generalized Order Statistics Under Iterated FGM family

  • Barakat, Haroon Mohammed;Husseiny, Islam Abdullah
    • Kyungpook Mathematical Journal
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    • 제62권2호
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    • pp.389-405
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    • 2022
  • We study the Fisher Information (FI) of m-generalized order statistics (m-GOSs) and their concomitants about the shape-parameter vector of the Iterated Farlie-Gumbel-Morgenstern (IFGM) bivariate distribution. We carry out a computational study and show how the FI matrix (FIM) helps in finding information contained in singly or multiply censored bivariate samples from the IFGM. We also run numerical computations about the FIM for the sub-models of order statistics (OSs) and sequential order statistics (SOSs). We evaluate FI about the mean and the shape-parameter of exponential and power distributions, respectively. Finally, we investigate the Kullback-Leibler distance in concomitants of m-GOSs.

STRONG CONVERGENCE OF AN IMPLICIT ITERATION PROCESS FOR A FINITE FAMILY OF STRONG SUCCESSIVELY $\Phi$-PSEUDOCONTRACTIVE MAPS

  • Chen, Rudong;Miao, Qian
    • East Asian mathematical journal
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    • 제24권1호
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    • pp.105-110
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    • 2008
  • The aim of this paper is to prove convergence of implicit iteration process to a common fixed point for a finite family of strong successive $\Phi$-pseudocontractive mappings. The results presented in this paper extend and improve the corresponding results of S. S. Chang [On the convergence of implicit iteration process with error for a finite family of asymptotically nonexpansive mappings, J. Math. Anal. Appl. 313(2006), 273-283], M. O. Osilike[Implicit iteration process for common fixed points of a finite finite family of strictly pseudocontractive maps, Appl. Math. Comput. 189(2) (2007), 1058-1065].

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