• Title/Summary/Keyword: m-chloroperbenzoic Acid

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The Oxidative Iodination of Pyrimidine Bases and their Nucleosides using Iodine/Dimethylformamide/m-Chloroperbenzoic Acid

  • Hwang, Chang-Ho;Park, Jung-Sup;Won, Jeong-Hee;Kim, Jae-Nyoung;Ryu, Eung K.
    • Archives of Pharmacal Research
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    • v.15 no.1
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    • pp.69-72
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    • 1992

  • Pyrimidine bases and their mucleosides were oxidatively iodinated at C-5 position by the reaction of iodine in DMF (dimethylformamide) with MCPBA (m-chloroperbenzoic acid) under mild conditions. For uracil derivatives such as uracil 1a. 1, 3-dimethyluracil 1b, uridine 1c, and 2'-deoxyuridine 1d, the corresponding 5-iodo derivatives were obtained in high yields (71-95%). The iodination of cytidine 3a and 2'-deoxycytidine 3b was achieved in moderate yields (41-56%).

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Halogenation of Cannabinoids (Cannabinoid의 할로겐화)

  • Baek Seung-Hwa;Park No-Yeun
    • Journal of the Korean Chemical Society
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    • v.35 no.1
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    • pp.59-63
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    • 1991

  • Several types of cannabinoids have been halogenated in the aromatic ring in good yields with metal halide in the presence of 18-crown-6 on oxidation with m-chloroperbenzoic acid. This reagent system effects the regiospecific halogenation of activated aromatic ring over olefinic double bond.

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A Selective Synthesis of Isoxazolo[2,3-${\alpha}$]quinoxalines and Pyrrolo[1,2-${\alpha}$]quinoxalines by 1,3-Dipolar Cycloaddition Reaction (1,3-쌍극성 고리화 첨가반응에 의한 Isoxazolo[2,3-${\alpha}$]quinoxaline류와 Pyrrolo[1,2-${\alpha}$]quinoxaline류의 선택적인 합성)

  • Kim Ho Sik;Nam Soon Hwa;Kurasawa Yoshihisa
    • Journal of the Korean Chemical Society
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    • v.34 no.5
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    • pp.469-475
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    • 1990

  • The reaction of 2,6-dichloroquinoxaline (13) with m-chloroperbenzoic acid gave 2,6-dichloroquinoxaline 4-oxide (14), whose reaction with pyrrolidine or indoline provided 2-substituted 6-chloroquinoxaline 4-oxides (15). The isoxazolo[2,3-a]quinoxalines (16) and pyrrolo[1,2-a]quinoxalines (17) were selectively synthesized from the 2-substituted 6-chloroquinoxaline 4-oxides (15) and dimethyl acetylenedicarboxylate. Moreover, the pyrrolo[1,2-a]quinoxalines (17) were found to be produced by the ring transformation of the isoxazolo[2,3-a]quinoxalines (16).

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Halogenation of Resorcinol Derivatives

  • Baek Seung-Hwa
    • Bulletin of the Korean Chemical Society
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    • v.9 no.1
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    • pp.13-15
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    • 1988

  • Several types of resocinols have been monobrominated in the ring in good yields with sodium bromide in the presence of 18-crown-6 on oxidation with m-chloroperbenzoic acid. Monoiodination takes place with 2'-(1-methylcyclohexen-3-yl)-5-(1,1-dimethylheptyl )-resocinol when sodium iodide is employed. This new reagent system, MX/18-crown-6/m-CPBA (M =$K^+, Na^+, X = Br^-, I^-X$ ), effects the regiospecific halogenation of activated aromatic ring over olefinic double bond.

  • https://doi.org/10.5012/bkcs.1988.9.1.13 인용 PDF

Epoxidaion of Unsaturated Poly (3-hrdroxyalkanoate)s with m-Chloroperbenzoic Acid

  • Park, Won-Ho;Robert W. Lenz;Steve Goodwin
    • Proceedings of the Korean Fiber Society Conference
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    • 1998.04a
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    • pp.45-49
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    • 1998

  • The production of unsaturated poly(3-hydroxyalkanoate)s, PHAs, by Pseudomonas oleovorans has been studied extensively in this laboratory$\^$1-3/, and recently a procedure has been developed for the quantitative conversion of the unsaturated groups to epoxide groups$^4$.(omitted)

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