• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 춘계학술대회 논문집
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• pp.1395-1396
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• 2010

• Journal of information and communication convergence engineering
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• 제9권5호
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• pp.562-566
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• 2011

As telecommunication technologies in telemedicine services are developed, the expeditious development of wireless and mobile networks has stimulated wide applications of mobile electronic healthcare systems. However, security is an essential system requirement since many patients have privacy concerns when it comes to releasing their personal information over the open wireless channels. Due to the invisible feature of mobile signals, hackers have easier access to hospital networks than wired network systems. This may result in several security incidents unless security protocols are well prepared. In this paper, we analyzed authentication and authorization procedures for healthcare system architecture to apply secure M-health systems in the hospital environment. From the analyses, we estimate optimal requirements as a countermeasure to its vulnerabilities.

• Nuclear Engineering and Technology
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• 제55권2호
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• pp.655-668
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• 2023

In radiography, an antiscatter grid is a well-known device for eliminating unexpected x-ray scatter. We investigate a new stationary grid artifact suppression method based on a nonsubsampled contourlet transform (NSCT) incorporated with Gaussian band-pass filtering. The proposed method has an advantage that extracts the Moiré components while minimizing the loss of image information and apply the prior information of Moiré component positions in multi-decomposition sub-band images. We implemented the proposed algorithm and performed a simulation and an experiment to demonstrate its viability. We did this experiment using an x-ray tube (M-113T, Varian, focal spot size: 0.1 mm), a flat-panel detector (ROSE-M Sensor, Aspenstate, pixel dimension: 3032 × 3800 pixels, pixel size: 0.076 mm), and carbon graphite-interspaced grids (JPI Healthcare, 18 cm × 24 cm, line density: 103 LP/inch and 150 LP/inch, ratio: 5:1, focal distance: 65 cm). Our results indicate that the proposed method successfully suppressed grid artifacts by reducing them without either reducing the spatial resolution or causing negative side effects. Consequently, we anticipate that the proposed method can improve image acquisition in a stationary grid x-ray system as well as in extended x-ray imaging.

• International Journal of Advanced Culture Technology
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• 제8권1호
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• pp.226-235
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• 2020

In this paper, we present to evaluate physiological activity of Robinia pseudo-acacia leaf and its skin penetration using liposome and cell penetrating peptide. After extraction with Robinia pseudo-acacia leaf using the distilled water and supercritical, various physiological activities were examined. In antioxidants experiments, the total concentration of polyphenol compounds was determined to be 56.88 mg/g in hydrothermal extract, 45.07 mg/g in supercritical extract. The DPPH radical scavenging ability at 1,000 ㎍/mL was 33.97% in supercritical extract. The scavenging effect on SOD experiment at 500 ㎍/mL was 76.41% in supercritical extract. In the antimicrobial experiments, the hydrothermal extract had no effect, but supercritical extract represented maximum clear zone of 14.00 mm in Staphylococcus aureus strain. Liposome containing the RSE (Robinia pseudo-acacia leaf supercritical extract) reduced particle size and stabilized zeta potential. In the epidermal permeability experiment, it was confirmed that the permeation of liposome containing the RSE and cell penetrating peptides was remarkable.

• 한국정보통신학회논문지
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• 제14권11호
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• pp.2435-2441
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• 2010

본 논문에서는 M2M 기반의 글로벌 헬스케어 모니터링 시스템을 구축하여 헬스케어 분야에 있어 기존의 센서네트워크의 확장성과 이동성을 보완하여 더욱더 안정적이고 신뢰성 있는 건강상태 정보를 제공하고자 하였다. 센서 노드는 웨어러블 심전도 및 맥파 센서와 결합되어 있으며, 각각의 생체신호를 수집하여 IEEE 802.15.4 표준 프로토콜과 6LoWPAN 프로토콜을 통해 외부 인터넷 망을 거쳐 서버로 전송한다. 또한 서버 프로그램은 측정된 생체신호를 통해 HRV 신호를 검출하였으며, HRV 신호를 이용한 시간 영역 및 주파수 영역 분석을 통해 환자의 스트레스 상태를 판단하도록 하였다. 이로써 제안된 시스템은 기존의 네트워크 인프라를 최대한 활용할 수 있는 장점을 가지고 있으며, 각각의 센서노드에 IP를 부여하여 헬스케어 서비스의 적용범위가 좁은 지역을 벗어나 범국가적으로 확대될 수 있도록 하였다.

• 한국응용과학기술학회지
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• 제37권6호
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• pp.1545-1555
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• 2020

In the present study, we investigated the antioxidant activity of Aucklandia lappa Decne (AL). Cell viability was measured in an MTT assay. Antioxidant effects were evaluated based on total polyphenol/flavonoid contents, ABTS radical scavenging activity, DPPH radical scavenging activity, SOD activity, and ROS content. AL was found not to be toxic at concentrations of 1 ㎍/mL, 10 ㎍/mL, and 100 ㎍/mL, respectively. The phenolic content was higher in AL-D than in AL-E, while the flavonoid content was higher in AL-E than in AL-D. AL-E exhibited higher ABTS radical scavenging activity than AL-D, and the EC50 values for BHA were 217.1 ㎍/mL in AL-D and 180.5 ㎍/mL in AL-E. AL-E also showed the highest DPPH radical scavenging activity. EC50 values for BHA were 114.2 ㎍/mL in AL-D and 95.8 ㎍/mL in AL-E. The SOD-like activity of AL-E was higher than that of AL-D. The EC50 values for ascorbic acid were 48.5 ㎍/mL in AL-D and 72.9 ㎍/mL in AL-E, indicating that both AL extracts have a SOD activity higher than that of ascorbic acid. AL-E reduced relatively more ROS than AL-D. With 100 ㎍/mL AL-E, the reduction level was almost similar to that of dexamethasone. Our results demonstrate that AL have antioxidant effects, and we believe that they could be very valuable as raw materials for anti-aging products, based on their antioxidant activity.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2014년도 추계학술발표대회
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• pp.457-459
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• 2014

최근 Wellness 산업과 스마트 디바이스가 융합되면서 기존의 질병관리 체계보다 앞서 예방하는 건강관리 u-Healthcare 가 개발되고 있다. 하지만 u-Healthcare 에서 취급되는 개인정보 및 의료정보는 메시지 탈취/변조로 인해 공격자에게 악용되어 의료사고를 유발하고 환자의 생명까지 앗아갈 수 있으며 또한 프라이버시 침해로 인해 사용자의 신변을 보장 받을 수 없다. 본 논문에서는 웰니스 서비스의 u-Healthcare 보안의 고려사항과 연구동향에 대해 살펴보고 현재 u-Healthcare 분야에서 보안이 적용된 시스템에 대해 분석하고 취급되는 정보보호의 중요성에 대해 고찰한다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 춘계학술발표대회
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• pp.702-705
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• 2010

요즘 현대인들의 최우선 관심사라고도 할 수 있는 '웰빙(Well-Being)'과 다가올 '고령사회'를 대비하여 유무선 네트워킹 기술을 활용하여 "언제 어디서나" 이용 가능한 건강관리 및 의료서비스가 필요하다. u-Healthcare 시스템을 이용하여 개인의 건강상태를 실시간으로 모니터링하고 치료나 관리가 필요한 적절한 시점에 자동으로 조치를 취하기 때문에 개인은 최상의 건강상태를 유지할 수 있고 편리한 한방 의료서비스를 제공받을 수 있다. 본 논문에서는 심전도(ECG), 혈압, 맥박 등의 생체신호 측정센서를 이용한 센서네트워크 기반 u-Healthcare 시스템을 설계하고 구현하였다. 센서노드에서 게이트웨이를 경유한 생체신호는 healthcare센터로 전송되며, 질환별 건강관리 표준 프로그램을 통하여 생체신호를 분석하고 예측된 병증에 관련된 운동요법, 식이요법, 한방요법 등의 정보를 환자에게 피드백하여 건강관리를 할 수 있게 하였다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제17권1호
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• pp.7-14
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• 2011

This paper is intended to suggest some reference materials for future specialization of university education about healthcare facility design in Korea, by reviewing the degree systems and curriculum of 5 universities where architecture departments have specialized program for healthcare facility design in USA. Research method includes the navigation of related homepages, the e-mail contacts with the professors in charge, and the analysis of collected materials. Some conclusions can be summarized as following : Degrees of the specialized programs under concentration or track system are awarded as the same title as master program in the department of Architecture. Specialized education programs can be largely classified by concentration/track systems( Clemson University, University of Kansas and Arizona State University) which are operated independently in general and certificate system(Texas A&M University and Texas Tech University) which adds some healthcare related courses to general master program in the department of Architecture. As distinctive curriculum from 5 Universities, Clemson University which offers almost courses related to healthcare facility design, University of Kansas which provides internships(6 credits each) for summer term & fall semester of 2nd year, and Texas Tech University where certificate program is co-operated by architecture and nursing department can be mentioned. In order to pursuit the specialization of university education about healthcare facility design in the department of Architecture, it would be desirable to proceed it after setting the direction such as concentration, track or certificate system according to the various circumstances & conditions of the department concerned.

• Clinical and Experimental Reproductive Medicine
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• 제42권4호
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• pp.149-155
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• 2015

Objective: The goal of this study was to investigate the relationship between serum progesterone (P4) levels on the day of human chorionic gonadotropin (hCG) administration and the pregnancy rate among women undergoing controlled ovarian stimulation for in vitro fertilization (IVF) or intracytoplasmic sperm injection-embryo transfer (ICSI-ET) using a flexible antagonist protocol. Methods: This prospective study included 200 IVF and ICSI-ET cycles in which a flexible antagonist protocol was used. The patients were divided into five distinct groups according to their serum P4 levels at the time of hCG administration (0.80, 0.85, 0.90, 0.95, and 1.00 ng/mL). The clinical pregnancy rate (CPR) was calculated for each P4 interval. Statistically significant differences were observed at a serum P4 level of 0.9 ng/mL. These data suggest that a serum P4 concentration of 0.9 ng/mL may represent the optimal threshold level for defining premature luteinization (PL) based on the presence of a significant negative impact on the CPR. Results: The CPR for each round of ET was significantly lower in the PL group defined using this threshold (25.8% vs. 41.8%; p=0.019), and the number of oocytes retrieved was significantly higher than in the non-PL group ($17.3{\pm}7.2$ vs. $11.0{\pm}7.2$; p=0.001). Elevated serum P4 levels on the day of hCG administration were associated with a reduced CPR, despite the retrieval of many oocytes. Conclusion: Measuring serum P4 values at the time of hCG administration is necessary in order to determine the optimal strategy for embryo transfer.