• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제17권3호
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• pp.186-190
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• 2014

Lymphocytic gastritis (LG) is a rare subtype of chronic gastritis. It is defined as dense proliferation of intraepithelial lymphocytes (IELs) more than 25 lymphocytes per 100 epithelial cells. The known major causes of LG are celiac disease and Helicobacter pylori infection. H. pylori associated LG (HpLG) has more enhanced cytotoxic and apoptotic tendencies than chronic H. pylori gastritis. A 12-year-old girl with postprandial epigastric pain was diagnosed HpLG on endoscopic biopsy. After the 1st eradication therapy, H. pylori bacilli were still found, and urea breathing test was positive. Although the endoscopic finding was partially improved, clinical symptoms and histologic finding were persisted. We could achieve the improvement of clinical symptoms and disappearance of IELs after the 2nd eradication. The discordant of histopathologic and endoscopic improvement occurred after the 1st eradication therapy of HpLG. Therefore the clinical and histopathologic evaluation should be considered as well as endoscopic findings.

• 한국임상수의학회지
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• 제31권2호
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• pp.108-111
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• 2014

7세 중성화된 암컷 고양이가 3개월 동안 지속된 간헐적인 구토 증상으로 진료 의뢰되었다. 혈액 검사와 진단영상학적 검사에서 비정상적인 소견은 관찰되지 않았다. 내시경 검사에서 위 동체 점막에 국소적인 미란이 관찰되었고, 해당 병변들에 대한 조직병리학적 검사를 통해 림프구성 위염으로 진단하였다. 프레드니솔론 투약 7일 후에 구토 및 식욕 부진 증상은 소실되었지만, 장기간 투약에 의한 부작용 발생 때문에 프레드니솔론 대신에 싸이클로스포린을 처방하였다. 환자의 상태는 개선되었고, 구토와 식욕부진은 더 이상 관찰되지 않았다. 본보는 만성 구토를 보이는 고양이 림프구성 위염에 있어 싸이클로스포린은 치료 약물로 적용 가능함을 시사한다.

• 대한수의학회지
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• 제49권1호
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• pp.79-83
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• 2009

A 6-year-old, spayed female Miniature Pinscher dog with chronic vomiting lasted for 7 weeks was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Physical examination, complete blood counts, serum chemistry, gastroscopy, upper gastrointestinal series, endoscopic biopsy and histopathological examination were performed for the diagnosis. The complete blood counts and serum biochemistry revealed no remarkable effect to the patient's general condition. Gastroscopy revealed erosion, erythema in mucosal surface of gastric lesions and endoscopic biopsy performed. No significant findings in upper gastrointestinal series were observed, and histopathologic examination revealed infiltration of lymphocyte in the gastric mucosa. Based on these findings, the dog was diagnosed with lymphocytic gastritis. The dog were treated by metronidazole and ranitidine with hypoallergenic diet, and then the patient showed no vomiting or other complications.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 춘계학술대회
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• pp.261-261
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• 2009

• 한국수의병리학회지
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• 제5권1호
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• pp.5-8
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• 2001

Prevalence of Helicobacter infection in pet dogs and positive relations between the presence of Helicobacter app. and gastritis were studied. Twenty-one dogs, which died of various disease, were referred from three animal hospitals and necropsied. Upon histopathological examination, Helicobacter-like organisms (HLO) were observed only in the gastric mucosa of 5 (23.5%) out of the 21 stomachs. The bacteria mainly colonized in the mucus, gastric pits, and the lumen of gastric glands. Regardless of HLO infection, there was mild to moderate lymphocytic infiltration in fundic and pyloric mucosa. Average gastritis scores of the group infected with HLO were 1.250${\pm}$0.214 and 1.833${\pm}$0.167 in the fundic and pyloric mucosa, whereas those of uninfected group were 1.000${\pm}$0.165 and 1.625${\pm}$0.239, respectively. Accordingly, we concluded that no association exists between HLO infection and gastritis.