• Title/Summary/Keyword: low-oxygen

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Selective Phase Transformation of Arsenopyrite by Microwave Heating and their Enhancement Au Recovery by Thiocyanate Solution (마이크로웨이브 가열에 의한 황비철석의 선택적 상변환과 티오시안산염 용액에 의한 Au 회수율 향상)

  • Han, Oh-Hyung;Kim, Bong-Ju;Cho, Kang-Hee;Choi, Nag-Choul;Park, Cheon-Young
    • Journal of the Mineralogical Society of Korea
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    • v.27 no.2
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    • pp.73-83
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    • 2014
  • In order to investigate selective phase transformations and to determine the maximum Au leaching factors from microwave treated Au-bearing complex sulfides, a microscope, SEM-EDS analysis, and thiocyanate leaching tests were performed. When the Au-bearing complex sulfides were exposed to microwave heating, increasing the microwave exposure time increased temperature and decreased weight. Arsenopyrite was first selectively transformed to hematite, which formed a concentric rim structure. In this hematite, oxygen and carbon was detected and always showed high iron content and low arsenic content due to arcing and oxidation from microwave heating. The results of the leaching test using microwave treated sample showed that the maximum Au leaching parameters was reached with 0.5 g concentration thiocyanate, 2.0 M hydrochloric acid, 0.3 M copper sulfate and leaching temperature at$60^{\circ}C$. Under the maximum Au leaching conditions, 59% to 96.69% of Au was leached from the microwave treated samples, whereas only 24.53% to 92% of the Au was leached from the untreated samples.

A New Sterol Regulatory Element Binding Protein, SrbB Is Critical for Hypoxia Adaptation and Virulence in the Human Fungal Pathogen Aspergillus fumigatus

  • Chung, Dawoon;Barker, Bridget M.;Carey, Charles C.;Merriman, Brittney;Werner, Ernst R.;Lechner, Beatrix E.;Dhingra, Sourabh;Cheng, Chao;Xu, Wenjie;Blosser, Sara J.;Morohashi, Kengo;Mazurie, Aurelien;Mitchell, Thomas K.;Haas, Hubertus;Mitchell, Aaron P.;Cramer, Robert A.
    • 한국균학회소식:학술대회논문집
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    • 2015.05a
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    • pp.15-15
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    • 2015
  • Aspergillus fumigatus is a major cause of invasive aspergillosis (IA), a significant health issue worldwide with high mortality rates up to 95%. Our lab is interested in how A. fumigatus adapts to low oxygen conditions 'hypoxia', which is one of the important host microenvironments. A. fumigatus SrbA is a basic helix-loop-helix (bHLH) transcriptional regulator and belongs to sterol regulatory element binding protein (SREBP) family members. Loss of SrbA completely blocks growth in hypoxia and results in avirulence in murine models of IA suggesting an essential role of SrbA in hypoxia adaptation and virulence in A. fumigatus. We conducted chromatin immunoprecipitation sequencing (ChIP-seq) with A. fumigatus wild type using a SrbA specific antibody, and 97 genes were revealed as SrbA direct targets. One of the 'SrbA regulons' (AFUB_099590) was a putative bHLH transcriptional regulator whose sequence contained a characteristic tyrosine substitution in the basic portion of the bHLH domain of SREBPs. Therefore, we designated AFUB_099590 SrbB. Further characterization of SrbB demonstrated that SrbB is important for radial growth, biomass production, and biosynthesis of heme intermediates in hypoxia and virulence in A. fumigatus. A series of quantitative real time PCR showed that transcription of several SrbA regulons is coordinately regulated by two SREBPs, SrbA and SrbB in hypoxia. This suggests that SrbA and SrbB have both dependent and independent functions in regulation of genes responsible for hypoxia adaptation in A. fumigatus. Together, our data provide new insights into complicated roles of SREBPs in adaptation of host environments and virulence in pathogenic fungi.

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Studies on the Geology and Geochemistry in the Beonam Mine, Korea (전북 번암광산의 지질과 지화학적 연구)

  • Chung, Jae-Il;Na, Choon-Ki;Lee, Young-Up;Jeon, Seo-Ryeong;Kim, Seon-Young
    • Economic and Environmental Geology
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    • v.28 no.6
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    • pp.623-633
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    • 1995
  • The Beonam deposits which is located in south-western part of Sobaeksan massif are emplaced along $N20{\sim}30^{\circ}E$ trending fissures in Precambrian Sobaeksan gneiss complex. Surrounding granites are inferred to be differentiated and formed from calc-alkaline magma which was generated from remelting or partial melting of the crustral material having igneous composition. The Sr isotope data of ore minerals showing significantly low initial Sr value relative to those of surrounding granite batholiths suggest that the ore-bearing fluid formed the Beonam Au-Ag mine are isotopically distinct from those of the wall rocks, and it indicates that there is no evidence of genetic relationship between ore-bearing fluids and surrounding granites, although further study should be needed. The results of paragenetic studies suggest three stages of hydrothermal mineralization; stage I: base-metal sulfides stage, stage II: late base-metal sulfides, electrum and silver-bearing sulfosalts stage, stage III: minor silverbearing minerals, barren quartz and carbonates stage. The temperature, salinity and pressure of the Beonam deposits estimated from mineral assemblage, chemical composition, fluid inclusion and sulfur isotope geothermometry are as follows; stage I: $200{\sim}315^{\circ}C$, 3.5~6.5 NaCl eq. wt%, 0.28~0.61 Kbar, stage II: $150{\sim}235^{\circ}C$, 4.5~7.4 NaCl eq. wt%, 0.11~0.15 Kbar. The estimated oxygen and sulfur fugacity during first stage mineralization, based on phase relation of associated minerals, range from $10^{35.1}{\sim}10^{-39.7}$ atm. and $10^{-11.0}{\sim}10^{-13.4}$ atm., respectively. All these evidences suggest that the Beonam deposits are polymetallic meso-epithermal ore deposits.

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Standardization of Underground Shopping Center Address System for the Three-Dimensional GIS-based Emergency Management (3차원 GIS기반의 소방방재를 위한 지하상가 주소체계 표준화)

  • Ha, Byeong Po;Kang, In Joon;Hong, Soon Heon;Park, Dong Hyun
    • Journal of Korean Society for Geospatial Information Science
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    • v.22 no.4
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    • pp.63-69
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    • 2014
  • Due to population growth and urban development in construction technology has expanded living space, underground construction as public transport as has been extended to the ground and underground urban traffic congestion increases. This underpass Stations sphere of influence this development was the center of the living space, space-time became a cultural space. However underpass ground space and time and space are enormous difficulties in contrast visibility due to smoke when light levels are low fire occurs, momentary loss of judgment errors due to a sense of orientation, rapid diffusion and ambient oxygen deficiency due to acquisition limitations, such as the Open resulting in property damage and personal injury. The purpose of this study is to analyze the existing system with respect to the address of the underground shopping center and system for presenting an address to the underground shopping mall in the basement of the straight and circular in connection with the street name address. Also can be known only to evacuate their citizens to address the position in the event of a fire inside the basement through the underground shopping mall address standardization system, the fire department only address exact location is being judged will be identified.

Studies of Refractive Index and Hardness from the structures in Quarternary Li2O-B2O3-Al2O3-SiO2 Glasses (4성분 Li2O-B2O3-Al2O3-SiO2 유리들의 구조로부터 굴절률과 경도 연구)

  • Moon, Seong-Jun
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.27-31
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    • 2002
  • Quarternary $Li_2O-B_2O_3-Al_2O_3-SiO_2$ glasses were fabricated by the function of $R({\equiv}Li_2Omole%/B_2O_3mole%)$ and $K({\equiv}(Al_2O_3mole%+SiO_2mole%/B_2O_3mole%)$. The structures of these glasses were investigated through refractive index and Vicker's hardness. The refractive index increased as the increase of the polarizability in the glass network. In the region of low $Li_2O$ content, the refractive index increased due to the increase of the polarizability in the glass network but, in the region of high $Li_2O$ content, the rate of increase of the refractive index decreased due to the increase of the molar volume caused by the formation of $BO_3{^-}$ units with relatively high molar volume. And, the refractive index decreased as the increase of $Al_2O_3+SiO_2$ content with the molar volume in the glass network. The increase and decrease of vicker's hardness values for those glasses depended on the fraction of tetrahedral $BO_4$ units and it of triangle $BO_3{^-}$ units with non-bridging oxygen, respectively.

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Psychological burden for legal responsibility of 119 emergency personnels (119구급대원의 법적책임에 대한 심리적 부담감)

  • Lim, Jae-Man;Yun, Seok-Jeong;Lim, Gwan-Su;Kang, Shin-Kap;Choi, Eun-Sook;Seo, Kyung-Hee
    • The Korean Journal of Emergency Medical Services
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    • v.13 no.1
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    • pp.87-96
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    • 2009
  • Purpose : To grasp the mental burden for legal responsibility that rescue members have in the performance of job. Method : Questionnaire was presented to rescue members serving in 2 direct control safety centers of fire station located in Seoul, Daejon, Incheon, Kwangju, Busan, Daegu and Ulsan. Results : 1. Questioned whether they have mental burden for legal responsibility while performing job on the site, the rescue members responded : very burdensome in 38.0%, burdensome in 56.0%, moderate in 4.5%, not burdensome in 1.0%, no burden at all in 0.5%. 2. Questioned on the first aid treat for which they have the most mental burden, the rescue members responded : intubation into trachea laryngeal mask airway(LMA) in 40.4%, automatic external defibrillator in 16.3%, securing vein providing sap(medicine) in 10.8%, basic cardiopulmonary resuscitation in 7.2%, eliminating foreign matters inserted into body in 5.4%, stanching external bleeding and treating injury in 5.4%, fixing extremities and spine by using splint in 1.8%, measuring the symptom of vitality in 1.2%, providing oxygen in 0.0%. 3. Questioned whether experiencing legal problem or firm petition(complaint) raised by patient while serving as rescue members, they responded : experiencing a complaint in 41.6%, experiencing no complaint in 58.4%. Asked to indicate the stress level in the scale of which they suffered when lawsuit or firm petition was raised, 0(weak)-10(strong), they answered 8.8 in average. 4. Questioned whether 119 rescue members put the legal responsibility in case that they cause damage to patients intentionally in performing, they responded to the inquiry 3.66 in average(of 5.00). It represented meaningful differences (F=2.874, p=.024) whether they had license or not. 5. In future, legal action will raise against the rescue member by 99% because of people's rights improvement(63.1%), high expectations for the rescue system(29.5%), non-licensed rescue members(5.1%). Conclusion : It was found that the rescue members had severe mental burden for advanced life support which was investigated to have low enforcement rate in the preceding research, for instance, intubation into trachea securing vein management by using automatic external defibrillator. To improve the qualitative level of rescue service in the fire fighting, it may be required to construct the environment that eliminates the mental burden of rescue members for legal responsibility.

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The Analysis of Water and Soil Environment at Farm Pond Depression (농지연못습지의 수질 및 토양환경 분석)

  • Son, Jin-Kwan;Kang, Bang-Hun;Kim, Nam-Choon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.13 no.3
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    • pp.46-62
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    • 2010
  • This study was conducted to understand the water and soil properties to propose the promotion of vegetation environment at farm pond depression. We selected 8 palustrine wetlands from agricultural area after consideration of human interference, surround land use, and size of area. Water quality analysis showed that the average SS, T-N, T-P were over the limit of agricultural water quality standard level at some sites. The cause for deterioration of water quality is supposed by the long-term stagnation of water in palustrine wetland. The recommended measures to improve water quality are as follows; improving water circulation by connecting with nearby natural water, preventing oxygen depletion by dredging deposit, lowering down T-N and T-P by removing autumn plants, preventing inflow of phosphorus in fertilizer ingredients which is the main cause for high T-P. The soil contamination of the surveyed area was about the same level of average heavy metal contents in soils from 2,010 paddy fields in Korea, which was much lower than soil contamination standards. As for soil texture, sand content was 40~90% and clay content was less than 20%. The content of silt and clay in soil from community of floating-leaved:submerged hydrophytes and community of emergent hydrophytes was higher that of soil from community of hygrophytes, and the content of sand in soil from community of hygrophytes was 10% higher than underwater soil. In terms of bulk density, the average was 0.24~0.96g/$cm^3$, which was quite low, because of high content of peat and organic matter in soil of the surveyed area. As for the average content of organic matter, community of floating-leaved:submerged hydrophytes was 18.25g/kg, community of emergent hydrophytes was 16.88g/kg, and community of hydrophytes was 25.63g/kg. The range of content of T-N in soil of community of floating-leaved;submerged hydrophytes was 0.022~0.307%, and that of community of emergent hydrophytes was 0.029~0.681% and that of community of hydrophytes was 0.088~0.325%. Apart from three sites in the surveyed area, most parts were over the standards or below the standard. After this study, we will conduct and discuss the relationship between vegetation characteristics and environments, which will be used of the best practical management and restoration of wetland.

Storage Quality of Ready-to-Eat Campbell Table Grapes as Affected by Active Modified Atmosphere Packaging (기체충진 포장조건에 따른 신선편이 캠벨 포도의 저장 중 품질변화)

  • Lee, Hyun-Hee;Hong, Seok-In;Kim, Dongman
    • Korean Journal of Food Science and Technology
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    • v.44 no.5
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    • pp.559-567
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    • 2012
  • The storage quality of ready-to-eat Campbell table grapes which were packaged under modified atmospheres was investigated in order to examine the effect of high $O_2$ and $CO_2$ on the fruit. Fresh table grapes with 10-15 berries were packed into polypropylene (PP) trays and were top-sealed with polythylene terephthalate/PP film. The initial gas compositions inside the packages were air, 20% $O_2$/10% $CO_2$/70% $N_2$, and 40% $O_2$/60% $N_2$. Sealed packages with low density polyethylene film bags and perforated PP trays were also used as a further treatment and control, respectively. The quality attributes were assessed during storage at $5^{\circ}C$ for 28 days. Fruit packaged in high $CO_2$ concentration showed the lowest viable cell counts of inherent microorganisms among all samples, although they suffered from severe off-flavors. High levels of $O_2$ significantly lowered flesh weight loss and maintained the flavor of grape. In an overall sensory aspect, the high $O_2$ and $CO_2$ packages exhibited greater scores than the air and control at the end of the storage period. Other quality attributes showed no significant differences among treatments. Results suggest that packaging with an appropriate combination of high $O_2$ and $CO_2$ can be used as an effective processing treatment for improvement of the storability of ready-to-eat table grapes.

The survival rate, respiration and heavy metal accumulation of abalone (Haliotis discus hannai) rearing in the different copper alloy composition (동합금 조성에 따른 북방전복 (Haliotis discus hannai)의 생존, 호흡 및 중금속 축적률)

  • Shin, Yun-Kyung;Jun, Je-Cheon;Myeong, Jeong-In;Yang, Sung-Jin
    • The Korean Journal of Malacology
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    • v.30 no.4
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    • pp.353-361
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    • 2014
  • In order to investigate the effects of copper alloy on abalone physiology, we studied survival rate, respiration, excretion rate, and heavy metal accumulation in each organ of adults and spats. The survival rate of spats and adults showed 27-60% and 63-83% respectively, higher survival rate in adults. In particular, 100% of copper panel led to lowest survival rate and there was no sharp distinction according to copper alloy composition. The respiration rate and excretion rate of ammonia nitrogen was $1.81mgO_2/g$ D.W./h and 0.43 mg $NH_4-N/g$ D.W./h respectively at 100% of copper panel. In other words, there was a high significant difference at the level, but no significant difference at other test levels (P < 0.05). The atomic ratio (0: N) hit the lowest at the 100% of copper panel showing 3.79 and no significant differences were seen among other test groups with 6.57-7.18 of a very low range. This means that the species might have undergone nutritional stress. In case of copper accumulation, the 100% copper panel group showed the highest level in hepatopancreas and muscle showing 6.91 mg/kg and 1.60 mg/kg respectively but the rest of groups showed similar levels. Zinc accumulation raised at Cu-Zn alloy panel had high significance showing 18.50 mg/kg and 1.10 mg/kg in hepatopancreas and muscle respectively (P < 0.05). To sum up, a cage net made of 100% pure copper is expected to have a negative effect on abalone in light of survival rate, heavy metal accumulation, and atomic ratio (0: N). Moreover, given that the substratum used for the high adhesive species and nutritious stress that is represented through the atomic ratio need to be considered, the copper alloy net is thought not to be suitable for abalone aquaculture.

Physiochemical Characteristics and Heavy Metal in the Surface Sediments of Marine Shellfish Farming Waters in Anjung Bay, Korea (안정만 패류양식해역의 표층퇴적물의 지화학적특성과 중금속 함량)

  • Jeong, Woo-Geon;Cho, Sang-Man;Lee, Sang-Jun
    • The Korean Journal of Malacology
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    • v.30 no.4
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    • pp.421-428
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    • 2014
  • Total 20 surface sediments were collected in Anjung bay to investigate the physicochemical environment and heavy metal contents. The physicochemical investigation ranged from 6.41% to 11.68% (average $9.52{\pm}1.28%$) for ignition loss (IL), from 17.99 mg/g to 43.84 mg/g (average $27.53{\pm}6.39mg/g$) for chemical oxygen demand (COD), and from 0.05 mg/g to 0.61 mg/g (average $0.17{\pm}0.14mg/g$) for acid volatile sulfide (AVS) with significant correlation between water content (W/C) and COD. A contour of spatial distribution indicated higher organic pollution at the bottom of ascidian, Stylea clava, cultural waters. Most of metals contents was not exceeded the NOAA's effect range-low (ERL). Estimated enrichment factor (EF) ranging 0.96-1.12 indicated that the sediment environment of the studied waters was relatively pristine from heavy metal pollution in spite of increased vessel traffics, so far.