• Title/Summary/Keyword: longterm

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A Study on the Long-Term Variations of Annual Maximum Surge Heights at Sokcho and Mukho Harbors (속초와 묵호항의 연간 최대해일고의 장기간 변동성에 대한 고찰)

  • Kwon, Seok-Jae;Moon, Il-Ju;Lee, Eun-Il
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.20 no.6
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    • pp.564-574
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    • 2008
  • This study investigates a long-term variation of annual maximum surge heights(AMSH) and main characteristics of high surge events, which is influenced by the global warming and intensifying typhoons, using sea level data at Sokcho and Mukho tidal stations over 34 years ($1974{\sim}2007$). It is found that the there is a longterm uptrend of the AMSH at Sokcho (8.3 cm/34yrs) and at Mukho (8.7 cm/34yrs), which is significant within 95% confidence level based on the linear regression. The statistical analysis reveals that 53% of the AMSH occurs during typhoon's event in both tidal stations and the highest surge records are mostly produced by the typhoon. It is concluded that the uptrend in the AMSH is attributed by the increasing typhoon activities globally as well as locally in Korea due to the increased sea surface temperature in tropical oceans. The continuous efforts monitering and predicting the extreme surge events in the future warm environments are required to prevent the growing storm surge damage by the intensified typhoon.

Flow Cytometric Analysis of Endothelial Cell Viability in Arterial Allograft (동종동맥판 혈관내피세포의 생육성 평가에 관한 연구)

  • 임창영;홍은경
    • Journal of Chest Surgery
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    • v.30 no.6
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    • pp.553-558
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    • 1997
  • Arterial allografts have known advantages over prosthetic vascular conduit for treatment of heart valvular disease, congenital heart disease and aortic disease. Cell viability may play a role in determining the longterm outcome of allografts. Endothelial cell is one important part in determining the allograft viability. To evaluate the viability of endothelial cells using current allograft preservation technique, porcine heart valve leaflets and arterial wall were subjected to collagenase digestion. Single endothelial cell suspension was labeled with GSA-PITC(Griffonia simplicifolia agglutininfluorescein isothiocyan te), a vascular, endothelial cell specific marker. The cell suspension was washed and incubated with Pl(Propidium iodide), which does not bind with viable cells, Endothelial cell viability was evaluated by calculating the percentage of GSA-FITC(+) and Pl(-) group using flowcytometric analysis. Allografts were treated with $4^{\circ}C$ antibiotic solo!ion for 24 hours for sterilization. After this, half of allografts were stored in $4^{\circ}C$ RPMI 1640 with HEPES buffer culture medium with 10% fetal bovine serum for 1 to 14 days(Group I). Another half of allografts were cryopreserved with a currently used technique (Group II). During the procurement and sterilization of arterial allografts, 22.8% and 24.4% of endothelial cell viability declined, respectively. In Group I, 11.9% of endothelial cell viability declined further steadily during 14 days of storage. In Group II, 13.7% of endothelial cell viability declined. These results show that largest loss of endothelial cell viability occurs during the nitial process. After 14 days of arterial allograft storage under $4^{\circ}C$ nutrient medium or cryopreservation, about 40% of endothelial cell viability is maintained. There were no differences between the endothelial cell viability from aortic valve leaflet, pulmonic valve leaflets, aortic wall and pulmonic wall.

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Case study of good soil management in plastic film-house cultivation (시설하우스 재배농가의 우수토양관리 사례연구)

  • Hyun, Byung-Keun;Kim, Lee-Yul;Kim, Moo-Sung;Cho, Hyun-Jun
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.2
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    • pp.98-104
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    • 2001
  • Cultivation area of the plastic film-house has been continuously increased with the increase of consumers' income. Intensive land use without fallowing or crop rotation caused severe problem such as salt accumulation in soils and in turn retarded growth and low productivity. This study was carried out to solve them derived from longterm intensive farming practices. Seven farmers who are practicing plastic film-house cultivation were recommended for case study by municipal government and selected for their excellency of cultivation and soil management. The cultivation periods of these systems were in the range of 5 to 40 years in the regions mainly located in alluvial soil cultivated with cucumber, tomato and red pepper. The soils texture of the excellent farmers' fields were silt loam or sandy loam, ranged from 7 to 15 percents of clay contents. Soil bulk density, depth of plowing layer and soil aggregates contents of the farmers' soils were 0.89, 23.1 cm, 61.6% whereas those in neighboring soils were 1.10, 17.8 cm, 54.2 %, respectively. And pH, OM and $NO_3-N$ of the farmers' soils also were better than those of neighboring soils. There was no difference in population densities of nematode between the good farmers' and neighboring soils, but actinomyces and Fusarium densities of recommended farmers' soils were better than neighboring soils. The major farming practices by the good farmers were characterized by deep plowing with flooding, amendment of crude organic matter, and reduction of chemical fertilizer application before transplanting, and also drip irrigation and liquid manure application after planting. They also conducted solar sterilization with or without flooding, removal of plastic films during rainy days and culturing rice or corn as rotation crops to avoid the problems mentioned above.

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The Effect of Refractive and Corneal Recovery after Discontinuation of Orthokeratology Contact Lenses in Children (각막굴절교정렌즈 어린이 착용자에서 착용 중지 후 굴절력과 각막형상 복귀에 관한 연구)

  • Mun, Mi-Young;Lee, Koon-Ja;Lee, Ji-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.14 no.3
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    • pp.7-15
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    • 2009
  • Purpose: To investigate the corneal recovery after discontinuing orthokeratology (OK) lenses wear in children for long-term period. Methods: Among the OK lens wearers who wear over 8 months and showed successful refractive correction, 25 subjects were selected who want to discontinue the OK lenses. Uncorrected visual acuity, refractive correction, corneal curvature (Sim K), central corneal thickness and corneal eccentricity were measured during the OK lens wearing period and after discontinuation for 1 month. Results: Uncorrected visual acuity and corneal shape had remodeled significantly during the OK lens wear and recovered significantly during the first week of discontinuation. Uncorrected visual acuity and refractive correction had achieved full recovery 2 weeks after discontinuation of lens wear and were highly correlated with the changes in corneal thickness. But corneal shape recovered slowly, eccentricity had recovered fully after 1 month and corneal curvature and central thickness had not been achieved full recovery until 1 month after discontinuation. Conclusions: Recovery of after longterm use of OK lens is rapid for refractive change, but slow for corneal curvature and central thickness that to refit the contact lenses, practitioners need patience.

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Evaluation of Growth between Breast-Fed and Formula-Fed Korean Infants from 1 to 3 Postpartum Months -Compared with the Korean Standard and NCHS Reference- (모유영양아와 인공영양아의 1~3개월의 성장발육 상태 평가-한국 표준치와 NCHS Reference간의 비교-)

  • 최경숙;구재옥
    • Korean Journal of Community Nutrition
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    • v.3 no.4
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    • pp.533-541
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    • 1998
  • This study compares the growth performance(weight-for-age Z-score, height-for-age Z-score, weight-for-height Z-score) of one- to three- month-old Korean infants(n=232) with the Korean standard(1994) and NCHS reference(1983). The weight-for-age Z-scores(WAZ) by the Korean standard were -2∼1,5 for males and -3∼1 for females. The NCHS reference, WAZ results were -1∼2.5 and -2.5∼3.5 for males and females, respectively. The WAZ compared Korean standard showed no subjects with overnutrition. But 1.3% of the infants showed signs of malnutrition. Comparison with NCHS reference revealed that 0.4% of the infants were malnourished and 7.0% of the infants were overnourished. The WAZ of formula-fed infants were distributed higher than breast-fed infants, but that was not significant. The height-for-age Z-score(HAZ) by the Korean standard were -4.5%∼1.5% for males and -4∼1.5% for females. According to the NCHS reference, HAZ were -2.5%∼2.5% and -3∼3 for males and females, respectively. When the WAZ was compared with the Korean standard, there was no overnutrition but 16% of the infants showed signs of malnutrition. The NCHS reference, revealed that 6.9% of the infants were malnourished and 1.8% of the infants were ovemourished. The weight-for-height Z-scores(WHZ) by the Korean standard were -2∼5 for males and -2.5∼5 for females. The NCHS reference WAZ scores were -1∼4 and -1.5∼4.5 for males and females, respectively. When the WHZ was compared with the Korean standard, 2.2% of infants were malnourished and 19.5% were overnourished. There were no malnourished subjects according to the NCHS reference and 19.1% of the infants were overnourished. When the three Z-scores are considered together, 92.0% of the infants should a normal growth status, there was no malnutrition, and 8.0% of the infants were overnourished. The growth performance was evaluated differently according to the type of standards. Thus, it is necessary to set proper growth standards for infants, according to which classification of feeding methods is chosen. A longterm and careful assessment of infants's growth performances to develop any group of standards.

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Meningeal Hemangiopericytomas : Clinical Features, Treatment and Long-term Outcome (수막 혈관주위세포종의 임상상, 치료 및 장기 추적 결과)

  • Lee, June-Ho;Hwang, Sung-Kyun;Gwak, Ho-Shin;Paek, Sun Ha;Kim, Dong Gyu;Kim, Hyun Jib;Jung, Hee-Won
    • Journal of Korean Neurosurgical Society
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    • v.30 no.7
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    • pp.876-882
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    • 2001
  • Objectives : Meningeal hemangiopericytoma is a rare tumor. Clinical and radiological features are similar to those of an ordinary meningioma. But its biological behavior is quite different from those of a meningioma as it brings profuse bleeding in the operation field, frequent recurrence and metastasis to other systemic organs even in the case of gross total resection. In order to find out the prognostic factors and to compare longterm outcome after various treatment modalities, the authors reviewed consecutive 20 operated cases of meningeal hemangiopericytoma to characterize their clinical features, surgical outcomes and effectiveness of the radiation therapy. Methods : Twenty patients with a hemangiopericytoma were treated between 1982 and 1999 in our department. They are composed of 13 patients of hemangiopericytoma and 7 patients who were initially diagnosed as angioblastic type meningioma and then confirmed as a hemangiopericytoma after review of their previous histopathology slides. The mean follow-up period was 99 months(1-256 months). The long-term outcomes after various treatment modalities were evaluated according to recurrence-free survival and image follow-up. Recurrence-free survival curves are compared between the patient groups according to the extent of removal and radiation therapy. Results : There were 10 cases of recurrence and 4 cases of distant metastases ; lung, liver and femur(2 cases) respectively. The 5-year recurrence rate was 37%, while the 10-year recurrence rose to 77%. There was also statistically significant difference of median recurrence-free survival between the completely-resected group(Simpson grade 1 or 2) and partially-resected group(Simpson grade 3 or 4 or 5) ; 137 months compared to 47 months, respectively(p=0.009). The median recurrence-free period after subtotal resection of tumor and postoperative radiotherapy was 47 months compared to 117 months of the patients who underwent gross total resection of tumor and did not receive radiotherapy. But radiation therapy alone did not show significant difference in recurrence-free survival. Marked tumor volume reduction and easy removal of tumors without bleeding were found in 2 recurred cases. Conclusion : The extent of tumor resection and presence of metastasis are the most important factors related to long-term outcome of the patients with hemangiopericytoma. Radiation therapy after the first operation did not have a role in extending the recurrence-free survival, but it affected favorably to decrease the size of residual mass and intraoperative bleeding during the second operation.

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Development of a Food Frequency Questionnaire for the Korea National Health and Nutrition Examination Survey: Data from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) (국민건강영양조사 식품섭취빈도조사지 개발: 국민건강영양조사 제4기 (2007-2009) 자료 이용)

  • Yun, Sung Ha;Shim, Jee-Seon;Kweon, Sanghui;Oh, Kyungwon
    • Journal of Nutrition and Health
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    • v.46 no.2
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    • pp.186-196
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    • 2013
  • The objective of this study was to develop a semi-quantitative food frequency questionnaire (FFQ) for an adult population for use in the Korea National Health and Nutrition Examination Survey (KNHANES). The 24-hour recall data for 2,939 subjects aged 19 years and over from the fourth KNHANES first year (2007) were used to extract the items included in the questionnaire. The FFQ items were developed by selection of major dishes based on the cumulative contribution rate, between-person variability based on the cumulative R2 of energy and 14 nutrients (carbohydrate, protein, fat, crude fiber, calcium, phosphorous, iron, sodium, potassium, vitamin A, thiamin, riboflavin, niacin, and vitamin C) and the number of consumers of each dish. In addition, the FFQ items were revised with analysis of 24-hour recall data of the fourth KNHANES second and third year (2008, 2009). Finally, 112 items were included in the FFQ and grouped as follows: rice (5 items), noodles and dumplings (6), breads and rice cakes (8), soups and stews (12), soybeans, eggs, meat and fish (23), vegetables, seaweed and potatoes (27), milk and dairy products (4), fruits (13), beverages (5), snacks (6) and alcoholic beverages (3). The food items of FFQ accounted for an average of 87.0% of energy and 14 nutrient intakes and also accounted for 81.7% of the between-person variability. The frequency range of the FFQ items was classified into nine categories (never or seldom, once per month, 2-3 times per month, once per week, 2-4 times per week, 5-6 times per week, once per day, twice per day and three times per day) and the portion size was divided into three categories (small, medium and large). We expect that this developed dish-based FFQ could be used in assessment of longterm dietary intakes of Korean adults.

A Measurement Way of Operation Risk Evaluation of Korean Seaports Using Negative DEA (Negative DEA를 이용한 국내항만의 운영위험평가 측정방법)

  • Park, Ro-Kyung
    • Journal of Korea Port Economic Association
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    • v.25 no.2
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    • pp.57-72
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    • 2009
  • The purpose of this paper is to show the empirical measurement way of operation risk evaluation in domestic seaports for overcoming the limitations which the traditional DEA method has by using 13 Korean ports in 2003 for 4 inputs(birthing capacity, cargo handling capacity, number of coastal guard vessel, number o f coastal special guard vessel ) and 5 outputs(Export and Import Quantity, Number of Ship Calls, number of coastal accident, number of coastal crime, number of coastal pollution). Because traditional DEA method has produced the limited set of information, negative DEA mixed with tier, stratification and layering methods should be adopted. The goal of negative DEA is to set up DEA models that will place the poor operating ports on or close to the empirical frontier. The core empirical results of this paper are as follows. First, Donghae ports should benchmark the operation way of Yeasu, Busan, Woolsan ports in terms of the middle and longterm base. Second, 5 ports(ports of Taean, Yeasu, Tongyoung, Busan, Sokcho) which were revealed as the poor operating ports in Negative DEA analysis should benchmark Incheon, Woolsan, Pohan, and Donhae ports. The policy implication to the Korean seaports and planners is that Korean seaports should introduce the new methods like Negative DEA of this paper for predicting the poor operating in the ports.

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Synoptic Change Characteristics of the East Asia Climate Appeared in Seoul Rainfall and Climatic Index Data (서울지점 강우자료와 기후지표자료에 나타난 동아시아 기후의 종관적 변화특성)

  • Hwang, Seok Hwan;Kim, Joong Hoon;Yoo, Chulsang;Chung, Gunhui
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.5B
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    • pp.409-417
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    • 2009
  • In this study it was assessed the accuracy of the Chukwooki rainfall data in Seoul by comparing with tree-ring width index data, sunspot numbers, southern oscillation index (SOI) and global temperature anomaly. And it was investigated the correlations of climatic change and change characteristics in past north-east asia by comparisons of tree-ring width index data in near Korea. The results of this study shows that Chukwooki rainfall data has the strong reliance since the trends and depths of change are very well matched with other comparative data. And with the results by compared with tree-ring width index data in six sites of near Korea, climates of north-east asia are changed with strong correlations as being temporal and spatial and longterm periodic possibility of reproducing are exist on those changes. However characteristics of climate change post 1960 A.D. are investigated as represented differently to past although statistical moving characteristics or changing criterion are within the limitations of reproducing phase in the past since they represent the different trends and irregularity and their frequencies are increase. The results of this study are widely used on long-term forecasting for climate change in north-east asia.

Korean Society of Heart Failure Guidelines for the Management of Heart Failure: Management of the Underlying Etiologies and Comorbidities of Heart Failure

  • Sang Min Park;Soo Youn Lee;Mi-Hyang Jung;Jong-Chan Youn;Darae Kim;Jae Yeong Cho;Dong-Hyuk Cho;Junho Hyun;Hyun-Jai Cho;Seong-Mi Park;Jin-Oh Choi;Wook-Jin Chung;Seok-Min Kang;Byung-Su Yoo;Committee of Clinical Practice Guidelines, Korean Society of Heart Failure
    • Korean Circulation Journal
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    • v.53 no.7
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    • pp.425-451
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    • 2023
  • Most patients with heart failure (HF) have multiple comorbidities, which impact their quality of life, aggravate HF, and increase mortality. Cardiovascular comorbidities include systemic and pulmonary hypertension, ischemic and valvular heart diseases, and atrial fibrillation. Non-cardiovascular comorbidities include diabetes mellitus (DM), chronic kidney and pulmonary diseases, iron deficiency and anemia, and sleep apnea. In patients with HF with hypertension and left ventricular hypertrophy, renin-angiotensin system inhibitors combined with calcium channel blockers and/or diuretics is an effective treatment regimen. Measurement of pulmonary vascular resistance via right heart catheterization is recommended for patients with HF considered suitable for implantation of mechanical circulatory support devices or as heart transplantation candidates. Coronary angiography remains the gold standard for the diagnosis and reperfusion in patients with HF and angina pectoris refractory to antianginal medications. In patients with HF and atrial fibrillation, longterm anticoagulants are recommended according to the CHA2DS2-VASc scores. Valvular heart diseases should be treated medically and/or surgically. In patients with HF and DM, metformin is relatively safer; thiazolidinediones cause fluid retention and should be avoided in patients with HF and dyspnea. In renal insufficiency, both volume status and cardiac performance are important for therapy guidance. In patients with HF and pulmonary disease, beta-blockers are underused, which may be related to increased mortality. In patients with HF and anemia, iron supplementation can help improve symptoms. In obstructive sleep apnea, continuous positive airway pressure therapy helps avoid severe nocturnal hypoxia. Appropriate management of comorbidities is important for improving clinical outcomes in patients with HF.