• Title/Summary/Keyword: locating

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Verifying Orthologous Paralogenes using Whole Genome Alignment

  • Chan, P.Y.;Lam, T.W.;Yiu, S.M.
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.109-112
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    • 2005
  • Identifying orthologous paralogenes is a fundamental problem in comparative genomics and can facilitate the study of evolutionary history of the species. Existing approaches for locating paralogs make use of local alignment based algorithms such as BLAST. However, there are cases that genes with high alignment scores are not paralogenes. On the other hand, whole genome alignment tools are designed to locate orthologs. Most of these tools are based on some unique substrings (called anchors) in the corresponding orthologous pair to identify them. Intuitively, these tools may not be useful in identifying orthologous paralogenes as paralogenes are very similar and there may not be enough unique anchors. However, our study shows that this is not true. Paralogenes although are similar, they have undergone different mutations. So, there are enough unique anchors for identifying them. Our contributions include the followings. Based on this counter-intuitive finding, we propose to employ the whole genome alignment tools to help verifying paralogenes. Our experiments on five pairs of human-mouse chromosomes show that our approach is effective and can identify most of the mis-classified paralog groups (more than 80%). We verify our finding that whole genome alignment tools are able to locate orthologous paralogenes through a simulation study. The result from the study confirms our finding.

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Measurements and Data Interpretation for the Detection of Steel Bars and Delamination inside Concrete (콘크리트내의 철근 및 공동탐사를 위한 측정과 분석)

  • Rhim, Hong-Chul;Park, Ki-Joon;Lee, Soong-Jae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.20 no.4
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    • pp.305-313
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    • 2000
  • To determine detection capabilities of locating steel bars and delamination inside concrete, commercially available nondestructive testing (NDT) equipments have been tested. The equipments include two radar systems and two electromagnetic method systems. The inclusions are a 19 mm diameter steel bar and 50 mm thick delamination embedded at different cover depths from the surface of concrete specimens. For the steel bar, attempts were made to determine the size of the bars by changing the diameter of the bars. A sample result of measuring horizontal spacing between doubly reinforced bars is presented in this paper. Experimental results on various measurement cases are discussed. Application of numerical modeling technique for the simulation of radar measurements and improved output display of radar measurements are also presented.

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A Study on Classification and Localization of Structural Damage through Wavelet Analysis

  • Koh, Bong-Hwan;Jung, Uk
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.11a
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    • pp.754-759
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    • 2007
  • This study exploits the data discriminating capability of silhouette statistics, which combines wavelet-based vertical energy threshold technique for the purpose of extracting damage-sensitive features and clustering signals of the same class. This threshold technique allows to first obtain a suitable subset of the extracted or modified features of our data, i.e., good predictor sets should contain features that are strongly correlated to the characteristics of the data without considering the classification method used, although each of these features should be as uncorrelated with each other as possible. The silhouette statistics have been used to assess the quality of clustering by measuring how well an object is assigned to its corresponding cluster. We use this concept for the discriminant power function used in this paper. The simulation results of damage detection in a truss structure show that the approach proposed in this study can be successfully applied for locating both open- and breathing-type damage even in the presence of a considerable amount of process and measurement noise.

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The Critical Success Factors of Six Sigma in China Manufacturing Industry

  • Yi-Zhong, Ma;Gang, Yue;Li-Lin, Wang;Ree, Sang-Bok
    • International Journal of Quality Innovation
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    • v.9 no.2
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    • pp.39-56
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    • 2008
  • Six Sigma has been one of main quality improvement approaches since Motorola first invented Six Sigma in 1987. Many scholars and consult experts have discussed the critical success factors of implementing Six Sigma management, but most of them are based on related theories or qualitative analyses. In the paper, we first review critical success factor of Six Sigma status quo based on literature. Then we design the questionnaire and survey China manufacturing enterprises that have introduced Six Sigma management. And finally, we analyze the critical success factors of China manufacturing industry implementing Six Sigma management by using structural equation model and find that leadership and Six Sigma strategy, focus on market and customer, evaluation and motivation, selecting, managing and implementing Six Sigma projects are four critical success factors of China manufacturing enterprises implementing Six Sigma management. At the same time, the paper also presents the relationships between the critical success factors. The results are of important role in China manufacturing industry locating resources, eliminating waste and improving Six Sigma performance.

V-shaped Pits in Regions of Ancient Baekje Kingdom Paleoparasitologically Confirmed as Likely Human-Waste Reservoirs

  • Shin, Dong Hoon;Shim, Sang-Yuck;Kim, Myeung Ju;Oh, Chang Seok;Lee, Mi-Hyun;Jung, Suk Bae;Lee, Geon Il;Chai, Jong-Yil;Seo, Min
    • Parasites, Hosts and Diseases
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    • v.52 no.5
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    • pp.569-573
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    • 2014
  • In a paleo-parasitological analysis of soil samples obtained from V-shaped pits dating to the ancient Baekje period in Korean history, we discovered Ascaris lumbricoides, Trichuris trichiura, and Clonorchis sinensis eggs. In light of the samples' seriously contaminated state, the V-shaped pits might have served as toilets, cesspits, or dung heaps. For a long period of time, researchers scouring archaeological sites in Korea have had difficulties locating such structures. In this context then, the present report is unique because similar kind of the ancient ruins must become an ideal resource for successful sampling in our forthcoming paleoparasitological studies.

Influence of Dither Motion on the Friction Coefficient of a Capsule-type Endoscope (디더 운동이 캡슐형 내시경의 마찰계수 감소에 미치는 영향)

  • Hong Y.S.;Choi M.J.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1068-1073
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    • 2005
  • Development of a locomotive mechanism for the capsule type endoscopes will largely enhance the ability to diagnose disease of digestive organs. In connection with it, most of the researches have focused on an installable locomotive mechanism in the capsule. In this paper, it is introduced that the movement of a capsule type endoscope in digestive organ can be manipulated by magnetic force produced outside human body. Since the magnetic force is provided by permanent magnets, no additional power supply to the capsule is required. Using a robotic manipulator for locating the external magnet, the capsule motion control system can cover the whole human digestive organs. This study is particularly concentrated on dither motion effect to improve the mobility of capsule type endoscope. It was experimentally found out that the friction coefficient between the capsule and digestive organ can be remarkably reduced by superposing yawing or rolling dither motion on the translatory motion. In this paper, the experimental results obtained while the direction, amplitude and frequency of sinusoidal dither motion were changed are reported.

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An Integration of Searching Area Extraction Scheme and Bi-directional Link Searching Algorithm for the Urban ATIS Application (도시부 ATIS 효율적 적용을 위한 탐색영역기법 및 양방향 링크탐색 알고리즘의 구현)

  • 이승환;최기주;김원길
    • Journal of Korean Society of Transportation
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    • v.14 no.3
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    • pp.45-59
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    • 1996
  • The shortest path algorithm for route guidance is implicitly required not only to support geometrical variations of transportation network such as U-TURN or P-TURN but to efficiency search reasonable routes in searching mechanism. The purpose of this paper is to integrate such two requirements ; that is, to allow U-TURN and P-TURN possibilities and to cut down searching time in locating routes between two points (origin and destination) in networks. We also propose a new type of link searching algorithm which can solve the limitation of vine building algorithm at consecutively left-turn prohibited intersections. The test site is a block of Gangnam road network that has some left-turn prohibited and allowed U-TURN intersections. Four models have been identified to be comparatively analyzed in terms of searching efficiency. The Models are as follows : (i) Model 1 - Link Searching Dijkstra Algorithm without Searching Area Extraction (SAE) ; (ii) Model 2 - Link Searching Dijkstra Algorithm with SAE ; (iii) Model 3 - Link Searching Bidirectional Dijkstra Algorithm without SAE ; and (iv) Model 4 - Link Searching Bidirectional Dijkstra Algorithm with SAE. The results of comparative evaluation show that Model 4 can effectively find optimum path faster than any other models as expected. Some discussions and future research agenda have been presented in the light of dynamic route guidance application of the urban ATIS.

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Ball-Bearing Selection Considering Flexibility of Shaft-Bearing System (축-베어링 시스템의 연성 특성을 고려한 볼 베어링의 선정)

  • 윤기찬;최동훈
    • Tribology and Lubricants
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    • v.16 no.1
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    • pp.39-45
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    • 2000
  • In this paper, the effects of shaft and bearing flexibilities are investigated for the accurate modeling of a shaft-bearing system supported by ball bearings. Generally, rolling bearings are modeled by simple rigid pin-joint in the mechanical design. However, they can no longer be modeled by ideal boundary conditions in the advanced applications because the rigid pin-joint model cannot satisfy the current trends of mechanical design decreasing mass and reducing volume. Consequently the flexible support model of ball bearing is investigated using the static analysis module developed by A .B. Jones and T. A. Harris. A simple two-bearing system, supported by two deep groove ball bearings and radially loaded on the shaft midway between the bearings, is utilized to validate the coupled model of shaft-bearing system. Numerical computations using the model indicate that the shaft span length, locating/floating bearing arrangements and applied bearing size are significant factors in determining the mechanical behaviors. The flexible support model of ball bearing can be escaped to over-estimate in the bearing fatigue life. The proposed simple design formulation obtained by numerical simulations can approximately predict a rate of bearing life reduction as a function of shaft span length/shaft diameter (L/d).

Optimal Location of Best Management Practices for Storm Water Runoff Reduction (우수유출저감 시설의 최적위치 결정)

  • Jang, Su Hyung;Lee, Jiho;Yoo, Chulsang;Han, Suhee;Kim, Sangdan
    • Journal of Korean Society on Water Environment
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    • v.24 no.2
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    • pp.180-184
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    • 2008
  • A distributed hydrologic model of an urban drainage area on Bugok drainage area in Oncheon stream was developed and combined with a optimization method to determine the optimal location and number of best management practices (BMPs) for storm water runoff reduction. This model is based on the SCS-CN method and integrated with a distributed hydrologic network model of the drainage area using system of 4,211 hydrologic response units (HRUs). Optimal location is found by locating HRU combination that leads to a maximum reduction in peak flow at the drainage outlet in this model. The results of this study indicate the optimal locations and numbers of BMPs, however, for more exact application of this model, project cost and SCS-CN reduction rate of structural facilities such infiltration trench and pervious pavement will have to be considered.

Study on the investigating termite damages of wooden structure using detector dog (탐지견을 활용한 목조건축물의 흰개미피해 조사 연구)

  • Jeong, So-Young
    • 보존과학연구
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    • s.31
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    • pp.121-130
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    • 2010
  • Wooden structures in Korea are usually damaged by some insects such as termites, wasps, cigarette beetles, powder-post beetles. Especially, the termites inhabiting in Korea are the subterranean termites, Reticulitermes speratus kyushuensis Morimoto, that make colonies in underground, therefore it is difficult to predict and control substantial infestations in advance. Accordingly, to enable inspectors to locate the termite infestations before the extensive damage occurs, the pest management industry has begun using several elaborate tools and making the various effect to inspect areas hard to access through a visual inspection. Recently detector dogs were adopted as one of those tools. Detector dogs are useful for locating subterranean termites because they use their acute olfaction rather than vision. We also have used detector dogs to locate termites and investigated 270 buildings from 31 sites since 2007. According to the results, while 144 buildings (53.4%) were in good condition with no damage by termites, 80 buildings (29.6%) were found out to be damaged by termites through visual inspection and detector dog. So it is expected to control termites according to the conservation status if detector dogs are well trained to discriminate live termites from fecal pellets by termites.

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