• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2531-2535
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• 2015

Background: Breast cancer diagnosed in young women may be more aggressive, with higher rates of local and distant recurrence compared to the disease in older women. Epidemiologic evidence suggests that Korean women have a lower incidence of breast cancer than women in the United States, but that they present at a younger age than their American counterparts. We sought to compare risk factors and management of young women with breast cancer in Boston, Massachusetts (US) with those in Seoul, South Korea (KR). Materials and Methods: A retrospective review was performed of consecutive patients less than 35 years old with a diagnosis of breast cancer at academic cancer centers in the US and KR from 2000-2005. Patient data were obtained by chart review. Demographic, tumor and treatment characteristics were compared utilizing Pearson's chisquare or Wilcoxon rank-sum tests where appropriate. All differences were assessed as significant at the 0.05 level. Results: 205 patients from the US and 309 from KR were analyzed. Patients in US were more likely to have hormone receptor positive breast cancer, while patients in KR had a higher rate of triple negative lesions. Patients in US had a higher mean body mass index and more often reported use of birth control pills, while those in the KR were less likely to have a sentinel node procedure performed or to receive post mastectomy radiation. Conclusions: Patients under 35 diagnosed with breast cancer in the US and KR differ with respect to demographics, tumor characteristics and management. Although rates of breast conservation and mastectomy were similar, US patients were more likely to receive post mastectomy radiation. The lower use of sentinel node biopsy is explained by the later adoption of the technique in KR. Further evaluation is necessary to evaluate recurrence rates and survival in the setting of differing disease subtypes in these patients.

• The Korean Journal of Pharmacology
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• v.27 no.2
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• pp.197-205
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• 1991

Local extravasation during intravenous administration of adriamycin (doxorubicin HCl) can cause severe skin ulceration and necrosis. To investigate the mechanism of adriamycin-induced skin toxicity, effects of adriamycin on reactive oxygen radical metabolism using cultured skin cells of fetal rat. Adriamycin produced significant release of lactic dehydrogenase from cultured skin cell preparations dose- and time-dependently. The production of superoxide anion in sonicated suspensions of cultured skin cells was significantly increased by adriamycin under the presence of NADPH and NADH. The drug also stimulated malondialdehyde (MDA) production, an index of lipid peroxidation, in NADPH- and NADH-supported cell preparations. The increased production of MDA was significantly inhibited by oxygen radical scavengers (superoxide dismutase, catalase, thiourea) and antioxidants (butylated hydroxytoluene, ${\alpha}-tocopherol$). Treatment of cultured skin cells with 1, 3,-bis (2-chloroethyl)-1-nitrosourea (BCNU), an inhibitor of glutathione reductase, enhanced the lipid peroxidation induced by adriamycin. The present study suggests that lipid peroxidation which is resulted from the stimulated production of reactive oxygen radical causes cellular damage in adriamycin-treated skin cells of rat.

• Journal of Astronomy and Space Sciences
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• v.26 no.4
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• pp.521-528
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• 2009

While it is well known that space environment can produce spacecraft anomaly, defining space environment effects for each anomalies is difficult. This is caused by the fact that spacecraft anomaly shows various symptoms and reproducing it is impossible. In this study, we try to find the conditions of when spacecraft failures happen more frequently and give satellite operators useful information. Especially, our study focuses on the geosynchronous satellites which cost is high and required high reliability. We used satellite anomaly data given by Satellite News Digest which is internet newspaper providing space industry news. In our analysis, 88 anomaly cases occurred from 1997 to 2008 shows bad corelation with Kp index. Satellite malfunctions were likely to happen in spring and fall and in local time from midnight to dawn. In addition, we found the probability of anomaly increase when high energy electron flux is high. This is more clearly appeared in solar minimum than maximum period.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.6
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• pp.349-356
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• 2015

Trace metals concentrations in the tissue of edible marine fish (4 species), olive flounder (Paralichthys olivaceus), Korean rockfish (Sebastes schlegelii), file fish (Stephanolepis cirrhifer) and abbysal searobin (Lepidotrigla abyssalis), collected near the Yongho wharf in Busan were determined to assess the potential human health risk (HRA) of trace metals by fish consumption. Levels of Li, Cr, Ni, Cu, Zn, As, Cd, and Pb in the fish tissue were $0.005{\pm}0.009$, $0.77{\pm}0.30$, $0.29{\pm}0.34$, $0.49{\pm}0.14$, $15.96{\pm}2.52$, $10.62{\pm}4.67$, $0.001{\pm}0.002$, and $0.045{\pm}0.06mg/kgdw$ respectively. The estimated daily intakes of Cu and Zn and the estimated weekly intakes of As, Cd, and Pb from the fish collected near the Yongho wharf were 0.0032, 0.054-0.18% of PMTDI (provisional maximum tolerable daily intake) and 13, 0.0041, 0.020% of PTWI (provisional tolerable weekly intake) which were set to evaluate the food safeties by the JFCFA (The Joint FAO/WHO Expert Committee on Food Additives). Lifetime cancer risk and target hazard for local residents due to those fish consumption were found to be negligible.

• The Journal of the Korea Contents Association
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• v.18 no.3
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• pp.114-123
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• 2018

Korea's Export Support Policy has shifted from conglomerate to SMEs since the 1998 IMF financial crisis. Therefore the SME export result in 2011 has reached the quantitative growth of more than US$ 100 billion for the first time. However, the trend has remained stagnant since 2013. Such a stagnant is judged to exist on the part of the Export Support Policies that fail to significantly enhance export competitiveness. Therefore, in order to expand the base of the export capabilities of SMEs and enhance the export competitiveness, the researcher has analyzed the problems of the Export Support Policy focused from the major prior studies since 2010 and derived the efficiency improvement methods. The results of this study are as follows: First, it is necessary to select or combine the following measures. they are the coordination or combination of the functions of the export support institutions, the operation of the single export support institutions, the utilization of the cooperative support system between the support institutions, the use of the private enterprises. First, it is necessary to review the following measures: they are the functional adjustment and integration among export support agencies, the adjustment of support organizations by export stage, the role coordinating between the Small and Medium Business Administration and the Local Government. Secondly, it is necessary to build a customized support system for enterprises. Thirdly, in order to secure the manpower and expertise of the support organization, it is necessary to review the utilization of the retired manpower the from the trade companies or the youth intern system. Fourthly, it is suggested that the balanced performance index is required for the export support programs with a certain scale and need to increase the portion the external evaluation together with the quantitative and qualitative evaluation.

• Korean Journal of Remote Sensing
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• v.27 no.5
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• pp.601-611
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• 2011

Land cover changes are occurring for a variety of reasons such as urbanization, infrastructure construction, desertification, drought, flood, and so on. Many researchers have studied the cause and effect of land cover changes, and also the methods for change detection. However, most of the detection methods are based on the dichotomy of "change" and "not change" according a threshold value. In this paper, we present a change detection method with the integration of probability, spatial autocorrelation, and hotspot detection. We used the AMOEBA (A Multidirectional Ecotope-Based Algorithm) and developed the AMOEBA-CH (core hotspot) because the original algorithm tends to produce too many clusters. Our method considers the probability of land cover changes and the spatial interactions between each pixel and its neighboring pixels using a local spatial autocorrelation measure. The core hotspots of land cover changes can be delineated by a contiguity-dominance model of our AMOEBA-CH method. We tested our algorithm in a simulation for land cover changes using NDVI (Normalized Difference Vegetation Index) data in South Korea between 2000 and 2008.

• Journal of Korea Water Resources Association
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• v.53 no.4
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• pp.313-322
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• 2020

There is always a risk of water disasters due to sudden storms in mountainous regions in Korea, which is more than 70% of the country's land. In this study, a radar-based risk prediction technique for sudden downpour is applied in the mountainous region and is evaluated for its applicability using Mt. Biseul rain radar. Eight local heavy rain events in mountain regions are selected and the information was calculated such as early detection of cumulonimbus convective cells, automatic detection of convective cells, and risk index of detected convective cells using the three-dimensional radar reflectivity, rainfall intensity, and doppler wind speed. As a result, it was possible to confirm the initial detection timing and location of convective cells that may develop as a localized heavy rain, and the magnitude and location of the risk determined according to whether or not vortices were generated. In particular, it was confirmed that the ground rain gauge network has limitations in detecting heavy rains that develop locally in a narrow area. Besides, it is possible to secure a time of at least 10 minutes to a maximum of 65 minutes until the maximum rainfall intensity occurs at the time of obtaining the risk information. Therefore, it would be useful as information to prevent flash flooding disaster and marooned accidents caused by heavy rain in the mountainous area using this technique.

• Journal of the Korean Dietetic Association
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• v.6 no.2
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• pp.125-135
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• 2000

Hypertension is a well-known degenerative disease whose prevalence rate increases with age. Management of high blood pressure is a critical concern in preventive strategies to reduce the morbidity and mortality for cardiovascular disease. The purpose of this study was to examine the dietary characteristics of hypertensive program participants, and to establish strategies based on their nutritional needs. Hypertensive patients were enrolled in the program in a public health center or in a local elderly center, at Suwon, in 1999-2000. Trained dietitians interviewed 62 enrollees(24-hour recall) and related variables. Mean body mass index of the subjects was 25.0kg/m². 30.7% of the subjects had a family history of hypertension. The majority of them ate regularly and partook of all available side dishes. They consumed grains and vegetables regularly, but seldom ate dairy products or food prepared with oil. Male enrollees frequently consumed more processed food and animal fat than did female enrollees(p<0.05). An analysis of the percentage of RDA(Recommended Dietary Allowances of Korea 1995) showed that but for ascorbic acid, enrollees consumed nutrients below the RDA. The food group intake pattern was not diverse, thus only 8.1% of enrollees consumed all food groups in a day. An analysis of eating attitude showed that 64.5% of enrollees always added salt to beef soup. Male enrollees showed low food-related self-efficacy compared to female enrollees, especially with reference to reduction of instant food intake(p<0.01), increase in vegetable intake(p<0.01), reduction of monosodium glutamate(MSG) intake(p<0.01). and not overeating(p<0.05). Their perceived barriers for participating in hypertension nutrition programs included lack of time, program necessity non-recognition, and program comprehension difficulty. These results suggest that nutrition education program necessity non-recognition, and program comprehension difficulty. These results suggest that nutrition education programs for community hypertensive patients should focus on increasing participant consumption of foods, expecially dairy products, and desirable eating attitudes. It also suggests that the program should consider should consider encouraging self-efficacy in changing eating behavior.

• Journal of the Korean Geographical Society
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• v.50 no.5
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• pp.485-503
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• 2015

This study aims at evaluating geomorphological classification systems to predict the occurrence of landslides in mountainous region in Korea. Geomorphological classification systems used in this study are Catena, TPI, and Geomorphons. Study sites are Gapyeong-gun, Hoengseong-gun, Gimcheon-si, Yeoju-si/Yicheon-si in which landslide occurrence data were collected by local governments from 2001-2014. Catena method has objective classification standard to compare among regions objectively and understand the result intuitively. However, its procedure is complicated and hard to be automated for the general public to use it. Both TPI and Geomorphons have simple procedure and GIS-extension, therefore it has high accessibility. However, the results of both systems are highly dependent on the scale, and have low relevance to geomorphological formation process because focusing on shape of terrain. Three systems have low compatibility, therefore unified concept are required for broad use of landform classification. To assess the effectiveness of prediction on landslide by each geomorphological classification system, 50% of geomorphological classes with higher landslide occurrence are selected and the total landslide occurrence in selected classes are calculated and defined as 'predictive ability'. The ratio of terrain categorized by 'predictive ability' to whole region is defined as 'vulnerable area ratio'. An indicator to compare three systems which is predictive ability divided by vulnerable area ratio was developed to make a comprehensive judgment. As a result, Catena ranked the highest in suitability.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.585-600
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• 2012

The purpose of this study related to the liquidity impact of the housing market variables using vector auto-regressive model(VAR) and empirical analysis is to derive some policy implications. October 2003 until May 2012 using monthly data for liquidity variables mortgage rates, mortgage, financial liquidity, as the composite index and nation, Seoul, Gangnam, Gangbuk, the Apartment sales prices were analyzed. Granger Causality Test Results, mortgage rates and mortgage at a bargain price two regions had a strong causal relationship. Since the impulse response analysis, Geothermal difference there, but housing price housing price itself, the most significant ongoing positive (+) reactions were liquidity-related variables are mortgage loans is large and persistent positive (+), financial liquidity weakly positive (+), mortgage interest rates are negative (-), KOSPI, the negative (-) reacted. Liquidity and housing prices that the rise can be and Gangnam in Gangbuk is greater than the factor that housing investment was confirmed empirically. Government to consider the current economic situation, while maintaining low interest rates and liquidity of the market rather than the real estate industry must ensure that activities can be embedded and local enforcement policies should be differentiated according to the policy will be able to reap significant effect.