• Title/Summary/Keyword: local changes

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The Effect of the Bojungikgi-tang in a Mouse Model of Allergic Rhinitis (포중익기탕(補中益氣湯)이 알레르기 비염(鼻炎) 유발 마우스에 미치는 효과(效果))

  • Kim, Sun-Min;Sim, Sung-Youn;Byun, Hak-Sung;Kim, Kyung-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.18 no.3
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    • pp.26-36
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    • 2005
  • Objectives: Maier symptoms of allergic rhinitis are nasal obstructions, sneezing and watery rhinorrhea. When exposed to certain allergens, the IgE covered mast cells degranulate and release inflammatory mediators and cytokines which result in a local inflammatory reaction. In many recent studies, molecular biological methods have been used to investigate the role of cytokines in pathogenesis and new therapeutic targets of allergic rhinitis. This experimental study was done to reveal the effects of the Bojungikgi-tang on the allergic rhinitis. We have studied effect of mice on OVA-induced production of IL-4, IL-5, $INF-{\gamma}$ by murine splenocytes and effect of OVA-induced Total IgE and OVA-specific IgE Meterial and Metheds: 21 BALB/c rats were divided into three groups: normal group, control group, experimental group. To induce the allergic rhinitis in control group and experimental group, rats were sentitized intraperitioneally with 0.1% ovalbumin solution 3 times at intervals of 2 weeks. Then intranasal sensitization was performed by diffusing 0.1% ovalbumin solution 3 times at intervals of 2 days for a week. After that time, rats in experimental group were oral administration treated by the Bojuogikgi-tang fer 28 days. We observed changes of IL-4, IL-5, $INF-{\gamma}$, Total IgE and OVA-specific IgE. We used independent-test statistically. Results: 1. In IL-4 study, Bojungikgi-tang treated group didn't show significant differences. 2. In IL-5 study, Bojungikgi-tang treated group shows significant differences. 3. In $INF-{\gamma}$ study, Bojungikgi-tang treated group shows significant differences. 4. In Total IgE, Bojungikgi-tang treated group shows significant differences. 5. In OVA-specific IgE, Bojungikgi-tang treated group didn't show significant differences. According to this result, Bojungikgi-tang was concluded to be effective on lowering the total IgE. Through this. Bojungikgi tang seems to reduce the symptoms of allergic rhinitis. More studies are required to know exact mechanism of Bojungikgi tang to show the anti allergenic effect.

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Development of interception capacity equations according to grate inlet types (빗물받이 형상에 따른 차집량 산정식 개발)

  • Choi, Sung Yeul;Eom, Kwangho;Choi, Seungyong;Cho, Jaewoong
    • Journal of Korea Water Resources Association
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    • v.49 no.10
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    • pp.851-861
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    • 2016
  • Recently, natural disasters, which are hard to predict and prevent, are rapidly increasing due to climate change worldwide. Particularly the damage scale of urban areas is increasing because of local torrential rainfall. In urban areas, the rain water cannot flow to pipes well due to the high percentage of impervious areas by the indiscriminate development. As a result, the inundation damage is getting higher in urban areas. So we need to characterize the interception of the grate inlets to ensure good drainage in impervious areas. But Korean installation criteria of grate inlets does not reflect road and drainage sector characteristics so the grate inlets do not function properly in many areas. In this study, we suggest the interception capacity equations about grate inlets through hydraulic experiments in various conditions. Therefore, the interception capacity changes are analyzed according to bearing bar slopes of grate inlets, grate inlet sizes and shapes and connecting pipe numbers. Though this, we developed the interception capacity equations about domestic grate inlets.

A Comparative Study on the Business and Financial Structure of Public Housing Agencies in Asia: Korea, Japan, Singapore and Hong Kong (아시아 공공주택기관의 사업특성 및 재무현황 비교 연구 : 한국, 일본, 싱가포르, 홍콩을 중심으로)

  • Kim, Yong-Tai;Park, Shin-Young;Cho, Seung-Youn
    • Land and Housing Review
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    • v.2 no.4
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    • pp.529-538
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    • 2011
  • Recently, one of the critical issues in Korea is the huge debt and future role of Korea Land and Housing Corporation. In this regards, the purpose of this study is to get implications from other public housing agencies in Asian countries such as UR of Japan, HDB of Singapore and HA of Hongkong. The changes of housing policy since 1960s, business and financial structure of housing agencies in each nation are investigated and compared. As a result, some policy directions can be proposed as follows : review of current mass housing program, relaxing qualifications for public rental housing, promotion of urban renewal projects, reinforcing cooperation with private sector and local governments, more government's support to LH's financing and loss from businesses for public interests and re-evaluation of LH's debt. The contribution of this study is that suggestions to improve housing policy and to alleviate financial problem of LH are based on the actual conditions of public housing agencies in Asian countries where the housing policy implementation system is similar to Korea, not on the theoretical basis.

A study of the elderly housing type development plan considering the Preconsumer Housing Characteristic -focused on Seoul metropolitan area- (예비 수요자 주택선호특성을 고려한 유형별 고령자주택 개발방안에 관한 연구 -수도권을 중심으로-)

  • Kim, Min-Chang;Won, You-Ho;Lee, Joo-Hyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.5
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    • pp.2844-2858
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    • 2014
  • The society experiencing the industrialization and urbanization has got over the socio-demographic change. these changes make the number of the population around the world, and this phenomenon is flowing into the whole country. Korea has became a Aging Society since 2000 and will be turned into the aged society by the 2018. therefore, the importance of preparing elderly living life such as silver town is getting emphasized. the purpose of this study is aimed at analyzing the decision elements of the preliminary demanders' intention who selecting Elderly Housing. Based on this study, it was broken down by the type much more. Binary Logistic Regression Analysis of Factors affecting the Elderly housing choices were subdivided. Through this process, improvement and the implications of this study was derived. this study deducts 3 kinds of implications. First, the preference for the development of elderly housing are different with each type of characteristics. Second, the indicators along with the individual characteristics account for the most part of the surface. so the specific investigation for the demand must be required to check the indicators. Third, when it comes to development of urban elderly housing, it requires to have a part of a local government plans securing the land. Fourth, when it comes to development of suburb elderly housing, it is required to arrange the living environment around the suburbs to let user classes living in Gyeonggi-do flow into elderly housing and live their new-life in the suburbs. Finally, when it comes to development of rural elderly housing, a variety of production, leisure and other programs should be made and put into there.

Optimized Handoff Scheme with Fuzzy logic in Heterogeneous Vehicular Mobile Networks (이종의 차량 모바일 네트워크에서 퍼지 로직을 이용한 최적의 핸드오프 기법)

  • Roh, Youngsam;Jeong, Jongpil
    • KIPS Transactions on Computer and Communication Systems
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    • v.1 no.1
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    • pp.35-46
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    • 2012
  • The development of wireless communication systems has resulted in the availability of several access technologies at any geographic area, such as 3G networks, wireless local area networks (WLANs) and wireless broadband networks. The development of these technologies is provided for users who have experienced mobile network environments which are slow or fast-movement environment and change distance between the AP(Access Point). This paper describes network performance issues in various environmental changes. Also, Fuzzy logic is applied to evaluate the performance in vehicle networks around users' environmental factors to focusing on the minimizing of transfer time and costs. First, WLAN and 3G networks fixed distance between AP, Second, WLAN and 3G networks random distance between APs, finally above two environmental with vehicle Ad hoc networks is analyzed. These V2I and V2V environmental condition are assumed. Results which based on Fuzzy logic suggest an optimal performance in vehicle network environments according to vehicle speed and distance between APs. Proposed algorithm shows 21% and 13% improvement of networks performance in V2I and V2V environment.

Development and Evaluation of the Educational Program for South Korean Middle School Students in Preparation for Reunification on North Korean Family Living Culture (중학생을 위한 통일대비 가정생활문화교육 프로그램 개발과 평가)

  • Lee, Hana;Kim, Yookyung;Song, Jieun;An, Soon-Hee;Lee, Yonsuk;Lee, Yhe-Young;Lee, Yoon-Jung;Lim, JungHa;Jung, Min-Young;Chung, SoonHwa;Han, Youngsun
    • Journal of Korean Home Economics Education Association
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    • v.29 no.3
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    • pp.105-124
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    • 2017
  • This study aimed at developing an educational program for South Korean adolescents on North Korean family living culture so that the students become familiar with the values and everyday lifestyles of North Korea. Understanding of North Korean culture is considered important as a foundation for social integration in prospect of future reunification. The contents of the program were developed based on the analysis of North Korean defectors' interviews and review of the literature and media reports on North Korean family culture. The program consists of 12 units of 40-minute sessions with the following topics: economy and consumption, leisure activities, family relationships, dating and spouse choices, fashion changes, clothing acquisition and care, food choices and local diets, dietary problems, housing, and neighborhood. The program was implemented between December 21 and 30, 2015 in a middle school located in Seoul. This program is expected to be useful in preparing the students as future leaders to create harmonious family living culture in the reunified Korea.

Differential Hrd1 Expression and B-Cell Accumulation in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis With Nasal Polyps

  • Chen, Kun;Han, Miaomiao;Tang, Mengyao;Xie, Yadong;Lai, Yuting;Hu, Xianting;Zhang, Jia;Yang, Jun;Li, Huabin
    • Allergy, Asthma & Immunology Research
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    • v.10 no.6
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    • pp.698-715
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    • 2018
  • Purpose: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unexplored. This study aimed to examine Hrd1 expression and B-cell accumulation and their possible roles in CRSwNP. Methods: Quantitative real-time polymerase chain reaction, immunohistochemistry, enzyme-linked immunosorbent assay and Western blotting were used to assess gene and protein expression in nasal tissue extracts. Cells isolated from nasal tissues and peripheral blood mononuclear cells were characterized by flow cytometry. Local antibody production was measured in tissue extracts with a Bio-Plex assay. Additionally, changes in Hrd1 expression in response to specific inflammatory stimuli were measured in cultured dispersed polyp cells. Results: Nasal polyps (NPs) from patients with eosinophilic CRSwNP (ECRS) had increased levels of Hrd1, B-cells and plasma cells compared with NPs from patients with non-eosinophilic CRSwNP (non-ECRS) or other control subjects (P < 0.05). The average Hrd1 levels in B-cells in NPs from ECRS patients were significantly higher than those from non-ECRS patients and control subjects (P < 0.05). NPs also contained significantly increased levels of several antibody isotypes compared with normal controls (P < 0.05). Interestingly, Hrd1 expression in cultured polyp cells from ECRS patients, but not non-ECRS patients, was significantly increased by interleukin-$1{\beta}$, lipopolysaccharide and Poly(I:C) stimulation, and inhibited by dexamethasone treatment (P < 0.05). Conclusions: Differential Hrd1 expression and B-cell accumulation between the ECRS and non-ECRS subsets suggests that they can exhibit distinct pathogenic mechanisms and play important roles in NP.

Effect of Slurry Composting and Bio-filtration (SCB) by Fertigation on Soil Chemical Properties and Growth of Red Pepper (Capsicum annuum L.)

  • Lee, Jong-Eun;Yun, Yeo-Uk;Lee, Jin-Il;Choi, Moon-Tae;Lee, Dong-Soek;Nam, Yun-Gyu
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.5
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    • pp.404-412
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    • 2015
  • The slurry composting and bio-filtration (SCB) liquid manure has some obvious advantages including a good source of N, P and K, local availability, effective microorganism and the ability to improve soil properties. This study was conducted to evaluate the influence on the changes of soil chemical properties and yield of red pepper by fertigation cultivation with SCB application for 2 years. Red pepper was transplanted in early May in 2013 and 2014. The treatment with three replication was composed of 4 types as control (N 1.0), SCB 0.5N, SCB 1.0N, and SCB 2.0N standards of recommended nitrogen fertilizer ($19kg\;N\;10a^{-1}$). The fertigation cultivation which was installed the surface drip irrigation system was splitted 10 times as $2.5Mg\;10a^{-1}$ nutritional solution included with chemical fertilizer and SCB every 10 days during the cultivation. The height and width of pepper plant were 7.0% and 5.8% higher in SCB 2.0N treatment than that in control. The yield of red pepper increased with the increasing of SCB application rates from SCB 0.5N to 2.0N. The yield of SCB 1.0N was much better 10% in average than that of control, and there was significant differences among all treatments. pH of control soil after final harvest decreased to 6.1, however pH of SCB treated soils increased from 6.7 to 7.1 depending on SCB application rates. The Exch.-K contents of SCB treated soils were increased 13.7 to 56.9% after final harvest compared with control by $0.51cmol_c\;kg^{-1}$. Accordingly, these results showed that SCB 1.0N application rate as a recommended nitrogen level based on soil testing can be used as an alternative nitrogen management as well as plant nutrition for red pepper cultivation.

Changes in the girth of anthropometric variables during menstrual cycle in women university students (여자대학생의 생리주기에 따른 인체계측변인 둘레의 변화)

  • Kim, Young-Sun;Kang, Seol-Hee;Kim, Yun-Jung;Park, Won-Yeop;Jang, Jee-Hun
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.14 no.5
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    • pp.421-429
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    • 2021
  • The purpose of this study was to identify the change in the girth of anthropometric variables during menstrual cycle, and to provide basal data for health promotion program development during pre-menstrual phase and menstrual phase. Participants were 10 healthy women university students without menstrual irregularity, subjective premenstrual syndrome, premenstrual dysphoric disorder, dymenorrhea, obstetrician and gynecologic disease. Chest girth(axillary and papillary), waist girth(half point between iliac crest and 12th rib, and navel), and hip girth were repeatedly measured in menstrual phase, follicular phase, luteal phase during single menstrual cycle. As a result, axillary chest girth in menstrual phase was significantly increased than that in luteal phase. Papillary chest girth and waist girth at half point between iliac crest and 12th rib in menstrual phase were significantly increased than those in follicular phase. No significance was shown in chest and waist girth between follicular and luteal phase. No significance was shown in hip girth during menstrual cycle. In conclusion, signicant difference was shown in chest and waist girth during menstrual cycle. And it is suggested that succeeding research should be carried out with reference to body weight, body fat, blood and local hormone concentration during menstrual cycle.

A Study on the Characteristics and Policy Demand of the Unmanned Vehicle Industry in Gyeonggi-do (경기도 무인이동체 산업 특성과 정책수요)

  • Kim, Myung Jin
    • Journal of the Economic Geographical Society of Korea
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    • v.24 no.3
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    • pp.283-299
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    • 2021
  • As the intelligent revolution triggered by digital technology, unmanned vehicles such as self-driving cars, robots, and drones appeared, which brought about innovative changes in the industry. Gyeonggi Local government has established both an ordinance and a basic plan regarding unmanned vehicles. It is time to prepare a data-based policy by understanding the current state of the unmanned vehicle industry in the province. As a result of the survey, the unmanned vehicle industry in Gyeonggi Province is 25% of the nationwide, and more than 88% is concentrated in the southern part of Gyeonggi Province. The land sector such as the robot and autonomous vehicles are focused on 71.4% and the aviation sector such as drones are 26.7%. However, unmanned vehicle companies in Gyeonggi-do are mostly small-sized businesses with less than 10 years of experience and are in the stage of introduction and growth level. They have a plan to improve technology through continuous R&D by hiring human resources. Therefore, Gyeonggi-do needs to consider policy support for sustainable growth of start-up and small enterprises and for fostering professional manpower and technical skills as well as for establishing an unmanned vehicle industry network to create, share, and spread knowledge.