• International Journal of Oral Biology
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• v.41 no.3
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• pp.113-118
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• 2016

An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator-activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for new applications of TRO, we investigated the cellular effects of TRO on YD15 tongue carcinoma cells. TRO suppressed the growth of YD15 cells in the MTT assay. The inhibition of cell growth was accompanied by the induction of cell cycle arrest at $G_0/G_1$ and apoptosis, which are confirmed by flow cytometry and western blotting. TRO also suppressed the expression of cell cycle proteins such as cyclin D1, cdk2, cdk4, cyclin B1, cdk1(or cdc2), cyclin E1 and cyclin A. The inhibition of cell cycle proteins was coincident with the up-regulation of $p21^{CIP1/WAF1}$ and $p27^{KIP1}$. In addition, TRO induces the activation of caspase-3 and caspase-7, as well as the cleavage of PARP. Further, TRO suppressed the expressions of Bcl-2 without affecting the expressions of Bad and Bax. Overall, our data supports that TRO induces cell cycle arrest and apoptosis on YD15 cells.

• Journal of Families and Better Life
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• v.21 no.2
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• pp.155-173
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• 2003

The purpose of this study was to gain an understanding about urban housewives' stress in family financial management, their coping strategies, and their sense of economic well-being, which will eventually provide some baseline data for policy development. The findings of this study are summarized in the following. First, the mean score of the level of financial management-related stress among urban housewives was 2.61 when the maximum level was set at 5. In order to overcome the stress from financial management, housewives utilized various strategies, such as purchasing management, financial planning, financial information gathering, getting a loan, and delaying payments. The average level of economic well-being among urban housewives was 2.82 when the maximum level was 5. Second, among socio-demographic factors, the family's monthly income and the husband's job satisfaction were the two most significant factors that affected the level of financial management stress among housewives. Third, there was a difference in employing coping strategies according to the level of stress. The group with a higher level of financial stress employed more coping strategies than the group with, a lower level of stress. Fourth, there were differences in the level of economic well-being, depending on the types of coping strategies employed. Fifth, the results from regression analyses, which were conducted to determine the relative explanatory power of different independent variable groups including subjective factors, financial management stress, and coping strategies, showed that socio-demographic and objective economic factors significantly affected economic well-being.

• The Korean Journal of Financial Management
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• v.26 no.2
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• pp.181-201
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• 2009

This study is on the forecasting performance analysis of range volatility estimators(Parkinson, Garman and Klass, and Rogers and Satchell) relative to historical one using two-scale realized volatility estimator as a benchmark. American sub-prime mortgage loan shock to Korean stock markets happened in sample period(January 2, 2006~March 10, 2008), so the structural change somewhere within this period can make a huge influence on the results. Therefore sample was divided into two sub-samples by May 30, 2007 according to Zivot and Andrews unit root test results. As expected, the second sub-sample was much more volatile than the first sub-sample. As a result of forecasting performance analysis, Rogers and Satchell volatility estimator showed the best forecasting performance in the full sample and relatively better forecasting performance than other estimators in sub-samples. Range volatility estimators showed better forecasting performance than historical volatility estimator during the period before the outbreak of structural change(the first sub-sample). On the contrary, the forecasting performance of range volatility estimators couldn't beat that of historical volatility estimator during the period after this event(the second sub-sample). The main culprit of this result seems to be the increment of range volatility caused by that of intraday volatility after structural change.

• Journal of the Korean Institute of Educational Facilities
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• v.27 no.2
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• pp.3-13
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• 2020

The purpose of this study was to analyze the factors negatively affecting college life, to investigate the perception gap between housing types, and to generate preliminary data for increasing residential satisfaction of students who live in temporary housing(e.g., dormitory or one-room). The utilized research methods included a questionnaire survey and an in-depth interview. The college students, especially from other regions, experienced more financial difficulties than others. They managed their tuition and living expense/allowance by parents supports and other sources(e.g., scholarship, arbeit, work in college, loan etc.). The reasons to choose dormitory, as temporary housing, were short distance to college and low costs. In case of one room, independent life was main reason to choose. Gender differences affected to the decision, moving away from present temporary housing. For example, male students preferred an independent life and a short commuting distance, while female students preferred an independent life and a safe life. Thus, considering the origin and gender differences of residents, dormitory planning needed to develop plans allowing independent life and to choose appropriate site for the purpose. In case of planning one room apartment, concerns for safety and landscape were more important than other factors.

• Journal of the Korean Society of Safety
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• v.13 no.3
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• pp.11-23
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• 1998

In this study, collapse test of thin-walled structure is performed under axially quasi-static and impact load in collapse characteristic to develop the optimum structural member for a light-oriented automobile. Furthermore, the energy-absorbing capacity is observed according to the variety of configuration(circular, square), aspect ratio in aluminum specimen to obtain basic data for the improved member of vehicle. In both quasi-static and impact collapse test, Al circular specimens collapse, in general, with axisymmetric mode in case of thin thickness while collapse with non-axisynmetric mode according to the thickness increase. For Al rectangular specimens, they collapse with axisymmetric mode in case of thin thickness, with mixed collapse mode according to the increase of thickness. In terms of initial max. load, Al square specimen turns out the best member among specimens, and then Al square, circular and circular with large scaling ratio, respectively. In case of quasi-static compression test, the absorbed energy per unit volume and mass shows higher in Al circular specimen, and then Al square, circular with large scaling ratio, respectively, according to shape ratio the absorbed energy per unit volume and mass in case of max. impact compression load is higher than that of static load. But the absorbed energy per unit volume and mass shows that Al circular specimen is the best member. Especially, unlike max. compression loan, the absorbed energy per unit volume and mass in impact test turns out the low value.

• Journal of Information Technology Services
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• v.14 no.3
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• pp.217-236
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• 2015

How does social interaction among investors affect decision-making in the online social lending platform? And what is the reason? In this study, in order to obtain the answer, we carried out case study research of Moneyauction and Popfunding, which are domestic online social lending platforms. We conducted interviews with managements of both social lending platforms and investors and analyzed statistical data including investment records, social interaction history between investors and lenders from both platforms. In addition, researchers performed direct participation and observation through the platforms as real investment members. As a result, we revealed that social interaction among investors has a material impact on the investment decision-making. Also we found that investors build trust by socially interacting with each other and this trust building leads to the investment decision making. Our findings confirm that social lending investors's decision-making process comply with the social embeddedness theory and imply that loan applicants must do their best efforts to display sincerity and truthfulness through their posting.

• The Journal of Industrial Distribution & Business
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• v.9 no.1
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• pp.25-38
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• 2018

Purpose - The purpose of this study is to empirically investigate the impact of donor's fiscal status on aid decisions before and after the 2008 global financial crisis. The effects on aid can change depending on the donor country's fiscal status and the period of financial crisis. Research design, data, and methodology - A fixed effect regression and dynamic panel GMM is conducted using a comprehensive dataset combining 31 donor and 167 recipient countries during 1996-2015. The key explanatory variable is central government debt-to-GDP ratio of donor country. Recipient countries' GNI per capita, population, governance indicators, and bilateral trade-to-GDP ratio between donor and recipient countries are included as control variables. Results - We can confirm the relationship between donor country's fiscal status and aid flow. The cyclical component of government debt is found to have a negative impact on grant decisions particularly after the 2008 global financial crisis. This effect becomes larger in the countries with high government debt-to-GDP ratio. ODA decisions from the countries with low financial constraint do not significantly affected by the recipient countries' factors such as GNI, population, and governance indicator. Conclusions - Based on the empirical results of this study, the source of aid should be diversified by incorporating private sector and innovative financing sources.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.9
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• pp.79-89
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• 2021

Green finance plays an important role in environmental protection missions and fighting climate change. The Environment Fund in Vietnam is the main channel of preferential capital offered to firms for environmental protection. Unfortunately, it was previously unknown which criteria influenced these companies' ability to obtain green financing. Using a survey method, we collected data through a structured questionnaire of 203 respondents that represent firms that had received concessional loans from 26 Environment Funds. A Multiple Linear Regression model was used to examine the determinants of access to concessional loans for environmental protection. We found relationships between age, size, ownership type, and industry sector, and access to green finance. Third-party guarantees were a significant factor in financing through Environment Funds. Moreover, we found commercial environmental projects face fewer green financing obstacles. Surprisingly, showing audited financial statements does not mitigate the information asymmetry between firms and these financial institutions. These findings suggest that Environment Funds should classify environmental project types to develop appropriate lending policies. In emerging markets, enterprises need to build a trusted relationship with financial institutions so that they can replace asset-based lending techniques, thereby increasing the firms' accessibility to green finance.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.5
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• pp.61-68
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• 2021

The exchange rate is considered a tool improving the volume of exports and reducing imports. This paper aims to determine the impact of the exchange rate on exports and imports between Vietnam and the United States in the context of the trade war. The research uses Autoregressive Distributed Lag (ARDL) and Nonlinear Autoregressive Distributed Lag (NARDL) Model in the time-series data from 2010:1 to 2020:9. The ARDL's results support that real exchange rate impact on export and import volumes, but less than the trade war. The trade war helps trade balance increase 0.35%, while the exchange rate increases trade balance 0.191% when the Vietnamese currency devalues 1% in the long run. In the short term, the real exchange rate makes the trade balance decrease. Therefore, the J curve exists between Vietnam and the U.S. The NARDL expresses that the exchange rate is asymmetric both in the short term and the long term. The findings of this study point to two important elements. Firstly, the exchange rate plays a minor role in exports and imports. Secondly, trade war plays a vital role in increasing exports and imports volume between two countries, and the J curve exists between the two countries.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.5
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• pp.829-837
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• 2021

The study investigates the impact of the Counter-Cyclical Buffer Policy (CCB) on regional development bank profitability in Sumatra, Indonesia. CCB requires banks to hold capital at times when credit is growing rapidly so that the buffer can be reduced if the financial cycle turns down or the economic and financial environment becomes substantially worse. This study employs time series data of regional development banks (RDBs) in Sumatra Island, Indonesia. The methodology applied in this study is a panel dynamic model with Generalized Methods of Moments (GMM). The results show that increasing capital through the implementation of CCB did not have a significant effect on RDBs' profitability. The findings of this study suggest that the activation and implementation of CCB lead to an increase in the amount and cost of loans to companies but do not affect the profitability of RDBs. The value of a Non-Performing Loan (NPL) proved to have a negative and significant effect on bank profitability. The CCB policy aims to overcome the pro-cyclicality of credit growth and improve bank resilience through increased capital which is expected to reduce excessive credit growth as a source of systemic risk. This causes a lack of lending to the community so that the profits obtained by the bank decrease.