• Journal of Radiation Protection and Research
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• v.32 no.4
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• pp.178-183
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• 2007

Neutrons are high LET (linear energy transfer) radiation and cause more damage to the target cells than x-rays or gamma rays. The damage from neutrons is generally considered fatal to a cell and neutrons have a greater tendency to cause cell death through direct interaction on DNA. We performed experiments to measure growth delay ratio and oxygen enhancement ratio (OER) in mouse model system. We inoculated EMT-6 cells to the right hind leg of BALB-c mouse and X-rays and neutron beams were given when the average volume of tumors reached $200-300mm^3$. We irradiated 0, 11, 15.4 Gy of X-ray and 0, 5, 7 Gy of fast neutron beam at normoxic and hypoxic condition. The volume of tumors was measured 3 times per week. In x-ray experiment, growth delay ratio was 1.34 with 11 Gy and 1.33 with 15.4 Gy in normoxic condition compared to in hypoxic condition, respectively. In neutron experiment, growth delay ratio was 0.94 with 5 Gy and 0.98 with 7 Gy, respectively. The OER of neutron beam was 0.97. The neutron beam was more effective than X-ray in the control of hypoxic tumors.

• Structural Engineering and Mechanics
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• v.11 no.2
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• pp.171-184
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• 2001

A direct discrete formulation suitable for the nonlinear analysis of masonry structures is presented. The numerical approach requires a pair of dual meshes, one for describing displacement fields, one for imposing equilibrium. Forces and displacements are directly used (instead of having to resort to a model derived from a set of differential equations). Associated and nonassociated flow laws are dealt with within a complementarity framework. The main features of the method and of the relevant computer code are discussed. Numerical examples are presented, showing that the numerical approach is able to describe plastic strains, damage effects and crack patterns in masonry structures.

• Computers and Concrete
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• v.7 no.4
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• pp.331-346
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• 2010

We present a quadrilateral finite element with an embedded crack that can be used to model tensile fracture in two-dimensional concrete solids and the crack growth. The element has kinematics that can represent linear jumps in both normal and tangential displacements along the crack line. The cohesive law in the crack is based on rigid-plasticity with softening. The required material data for the concrete failure analysis are the constants of isotropic elasticity and the mode I softening curve. The results of two well known tests are presented in order to illustrate very satisfying performance of the presented approach to simulate failure of concrete solids.

• JSTS:Journal of Semiconductor Technology and Science
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• v.15 no.6
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• pp.671-677
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• 2015

A novel phase interpolator (PI) based linear model of multipath ring oscillator (MPRO) is described in this paper. By modeling each delay cell as an ideal summer followed by a single pole RC filter, the oscillation frequency is derived for a 4-stage differential MPRO. It is analytically proved that the oscillation frequency increases with the growth of the forwarding factor ${\alpha}$, which is also confirmed quantitatively through simulation. Based on the proposed model, it is shown that the power to frequency ratio keeps constant as the speed increases. Running at the same speed, a 4-stage MPRO can outperform the corresponding single-stage ring oscillator (SPRO) with 27% power saving, making MPRO with a large forwarding factor ${\alpha}$ an attractive option for lower power applications.

• Computers and Concrete
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• v.27 no.1
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• pp.55-62
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• 2021

The concrete fatigue analysis can be performed with the use of fracture mechanics. The fracture mechanics defines the fatigue crack propagation as the relationship of crack growth rate and stress intensity factor. In contrast to metal, the application of fracture mechanics to concrete is more complicated and therefore many authors have introduced empirical expressions using Paris law. The topic of this paper is development of a new prediction of fatigue crack propagation for concrete using rheological-dynamical analogy (RDA) and finite element method (FEM) in the frame of linear elastic fracture mechanics (LEFM). The static and cyclic fatigue three-point bending tests on notched beams are considered. Verification of the proposed approach was performed on the test results taken from the literature. The comparison between the theoretical model and experimental results indicates that the model proposed in this paper is valid to predict the crack propagation in flexural fatigue of concrete.

• Magazine of the Korea Concrete Institute
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• v.9 no.3
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• pp.127-135
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• 1997

In this study, the wedge splitting tcst (WST) was carried out for the fatigue wack growth behavior of concrete. Selected test variables were concrete compressive strength of 28, 60 and 118 MI%, and stress ratio with 2 levels (6. 13%). In oder to make the designed stress ratio, the maximum and thr minimum fatigue loading level were 75-85% and 5- 10% of ultimate static load, respectively. Fatigue testing was preceded by crack mout.h opening displacement (CMOI)) compliance calibration tcst, and then the fatigue crack growth was computed by crack lcngth vs. (lMOI) compliance relations acquisited by the CMOD compliance calibration technique. To evaluate thc validity of CMOD compliancc calibration techniquc, the crack length p~mlicted by this method was cornpard with the crack length by linear elastic fracture mechanics(LEFIbl) and dyeing test. On the basis of the experimental results, a LRFhl-based c.mpirica1 model for f'at,igue crack growth rate(da/dN-AKI relationships) was presented. The fat,igut. crack growth ratc increased with the strength of concwtc. It appcars that t.he da/tiN-AKI relationships was influenced by stress ratio, however, the effect is diminished with an increase of strength. The comparisons between CblOl) compliance calibration technique anti the other. methods gave the validity of' ('MOD compliance calibration technique for the LZXT.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.4
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• pp.704-713
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• 1997

This study was conducted to describe qualitatively the protein metabolism of pigs during growth depending on the feed protein quality and to describe quantitatively amino acids requirements, using a simulation model. The used model has a non-linear structure. In the used model, the protein utilization system of a pig, which is in the non-steady-state, is described with 15 flux equations and 11 differential equations and is composed with two compartments. Protein deposition(g/day) of pigs on the 30th, 60th, 90th, and 120th day of feeding duration with three-quality protein, beginning with body weight 20kg, were calculated according to the empirical model, PAF(the product of amino acid functions) of Menke, and was used as object function for the simulation. The mean of relative difference between the simulated protein deposition and PAF calculated values, lied in a range of 8.8%. The simulated protein deposition showed different behavior according to feed protein quality. In the high-quality protein, it showed paraboloidal form with extending growth simulation up to 150eh day. So the maximum of protein deposition was acquired on the 105th day of simulate growth time and then it decreased fast. In the low-quality protein, this form of protein deposition in the course of simulated growth did not appear until 150th day. The simulated protein mass also showed a difference in accordance with feed protein quality. The difference was small on the 30th day of simulated growth, but with duration of the simulated growth it was larger. On the 150th day the simulated protein deposition of high quality protein was 1.5 times higher as compared to the low-quality protein. The simulated protein synthesis and break-down rates(g/day) in the whole body showed a parallel behavior in the course of growth, according to feed protein quality. It was found that the improvement of feed protein quality increased protein deposition in the whole body through a increase of both protein synthesis and breakdown during growth. Also protein deposition efficiency, which was calculated from simulated protein deposition and protein synthesis, showed a difference in dependence on the protein qualify of feed protein. The protein deposition efficiency was higher in pigs fed with high quality protein, especially at the simulation time 30th day. But this phenomena disappeared with growth, so on the 150th day of growth, the protein deposition of the high feed protein quality was lowest among the three different quality of feed protein. The simulated total requirement of the 10 essential amino acids for the growth of pigs was 28.1(g/100g protein), similar to NRC. The requirement of lysine was 4.2(g/100g protein).

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.581-587
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• 2023

The purpose of this study was to analyze the change trajectory and latent class types of self-esteem in first to fourth grade elementary school students. For the purpose, the Korean Children's Panel data were analyzed using potential growth model and the growth mixture model. As the results, the linear change model was selected as the most appropriate model. The change trajectory was found to increase slightly as the grade increased. In addition, four latent class groups were derived through: 'high level-maintenance,' 'low level-increase,' 'high level-decrease,' and 'low level-maintenance.' Most children were in the 'high level-maintenance' group, followed by 'high level-decrease,' 'low level-increase,' and 'low level-maintenance' groups. Therefore, based on the results of the study, we suggest that educational institutions and local communities pay attention to trends in elementary school students' self-esteem and provide appropriate support for students in each class.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.12
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• pp.1703-1709
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• 2008

As genetic markers, single nucleotide polymorphisms (SNP) are very appropriate for the development of genetic tests for economic traits in livestock. Several microsatellite markers have been identified as useful markers for the genetic improvement of Hanwoo. Among those markers, ILSTS035 was recently mapped at a similar position with four SNPs (AH1_11, AH1_9, 31465_446, and 12273_165) in a linkage map of EST-based SNP in BAT6. Among the four SNPs, two SNPs (31465_446 and 12273_165) were analyzed using BLAST at the NCBI web site. The sequences including the 12273_165 SNP were identified at the intron region within the LOC534614 gene on the gene sequence map (Bos taurus NCBI Map view, build 3.1). The LOC534614 gene represents a protein similar to myosin heavy chain, fat skeletal muscle, embryonic isoform 1 in the dog, and myosin_1 (Myosin heavy chain D) in Macaca mulatta. In cattle, the myosin heavy chain was associated with muscle development. The phenotypic data for growth and carcass traits in the 415 animals were analyzed by the mixed ANCOVA (analysis of covariance) linear model using PROC GLM module in SAS v9.1. By the genotyping of Hanwoo individuals (n = 415) to evaluate the association of SNP with growth and carcass traits, it was shown that the 12273_165 SNP region within LOC534614 may be a candidate marker for growth. The results of the statistical analyses suggested that the genotype of the 12273_165 SNP significantly affected birth weight, weight of the cattle at 24 months of age, average daily gain and carcass cold weight (p<0.05). Consequently, the 12273_165 SNP polymorphisms at the LOC534614 gene may be associated with growth in Hanwoo, and functional validation of polymorphisms in LOC534614 should be performed in the future.

• Computers and Concrete
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• v.7 no.4
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• pp.387-402
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• 2010

From typical stress-axial strain curve and stress-volume strain curve of a concrete under uniaxial compression, the initiation and localization of microcracks within the interior of the specimen can be identified. The occurrence of random microcrack indicates the end of the linear elasticity, and the localization of microcrack implies formation of major crack, which triggers the onset of unstable crack propagation. The interval between initiation and localization of microcracks is characterized by a stable microcrack growth. Based on fracture behavior observed from a uniaxial compressive test of a concrete cylinder, a model has been developed to extract fundamental fracture properties of a concrete, i.e. the equivalent fracture toughness and the size of fracture process zone. The introduction of cracking Poisson's ratio accounts for tensile failure characteristics of concrete even under uniaxal compression. To justify the validity of the model proposed, tests on three-point bending have been performed to obtain the fracture toughness in accordance with two parameter fracture model and double-K fracture model. Surprisingly, it yields favorably comparable results and provides an encouraging alternative approach to determine fracture properties for concretes.