• Genomics & Informatics
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• v.10 no.1
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• pp.40-43
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• 2012

Recent genomewide association studies of large samples have identified genes that are associated with blood pressure. The Global Blood Pressure Genetics (Global BPgen) and Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) consortiums identified 14 loci that govern blood pressure on a genomewide significance level, one of which is $CASZ1$ confirmed in both Europeans and Asians. $CASZ1$ is a zinc finger transcription factor that controls apoptosis and cell fate and suppresses neuroblastoma tumor growth by reprogramming gene expression, like a tumor suppressor. To validate the function of $CASZ1$ in blood pressure, we decreased $Casz1$ mRNA levels in mice by siRNA. $Casz1$ siRNA reduced mRNA levels by 59% in a mouse cell line. A polyethylenimine-mixed siRNA complex was injected into mouse tail veins, reducing $Casz1$ mRNA expression to 45% in the kidney. However, blood pressure in the treated mice was unaffected, despite a 55% reduction in $Casz1$ mRNA levels in the kidney on multiple siRNA injections daily. Even though $Casz1$ siRNA-treated mice did not experience any significant change in blood pressure, our study demonstrates the value of $in$ $vivo$ siRNA injection in analyzing the function of candidate genes identified by genomewide association studies.

• Journal of The Korean Astronomical Society
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• v.49 no.6
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• pp.255-259
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• 2016

We estimate the fractal dimension of the ${\rho}$ Ophiuchus Molecular Cloud Complex, associated with star forming regions. We selected a cube (${\upsilon}$, l, b) database, obtained with J = 1-0 transition lines of $^{12}CO$ and $^{13}CO$ at a resolution of 22" using a multibeam receiver system on the 14-m telescope of the Five College Radio Astronomy Observatory. Using a code developed within IRAF, we identified slice-clouds with two threshold temperatures to estimate the fractal dimension. With threshold temperatures of 2.25 K ($3{\sigma}$) and 3.75 K ($5{\sigma}$), the fractal dimension of the target cloud is estimated to be D = 1.52-1.54, where $P{\propto}A^{D/2}$, which is larger than previous results. We suggest that the sampling rate (spatial resolution) of observed data must be an important parameter when estimating the fractal dimension, and that narrower or wider dispersion around an arbitrary fit line and the intercepts at NP = 100 should be checked whether they relate to firms noise level or characteristic structure of the target cloud. This issue could be investigated by analysing several high resolution databases with different quality (low or moderate sensitivity).

• Journal of Korean Society for Atmospheric Environment
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• v.21 no.2
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• pp.215-226
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• 2005

In this study, we investigated the emission concentrations of 31 odorous compounds from various emission sources of 37 individual companies located within the Ban Wal industrial complex of Ansan city, Korea. In the course of our study, we attempted to evaluate emission characteristics of different industrial activities and relative significance of different odorous components . Based on our measurements of odorous compounds, we were able to find a line of evidence to draw a conclusion that a number of odorous compounds can be used as indices to specifically point out the influence of certain industrial activities. It was found that hydrogen sulfide and trimethyl amine record the highest contribution from leather industry. Likewise, acetaldehyde showed its maximum contribution from food-beverage sector, while ammonia for paper-mill, pulp production sector. On the other hand, the results of styrene and most YOC including BTEX were not useful, as their concentrations were not significantly high enough to judge from such respect.

• Ocean and Polar Research
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• v.32 no.2
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• pp.123-135
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• 2010

Around Tongyeong coasts which located in southern coast of Korea composed to the complex coastal line and scattered by small islands. It also has been distributed to a complicated bathymetric structure by several types of channels. This study carried to analyze the spatial characteristics of macrobenthic community and benthic environmental variance on sub-tidal area based on multivariate statistics tools. Sediment composition varied from muddy sand to mud, and along the channels, it composed to a heterogeneous bottoms mixed by shell fragment, cobbles and mud. Organic contents on the surface sediment varied 1.1-3.9%. Total of 272 species, $33,349\;ind./m^2$ of macrobenthos identified in all of sample area. Polychaetes also prevailed among the specimen. L. longifolia, P. pinnata dominated based on density. Considering on the biomass, echinoderm S. lacunosa, A. tricoides listed. Closer to the coastal area, the density and diversity were higher. Community structure based on cluster analysis was discriminated into three groups. Each group was also characterized by geographical state such as depth, sediment composition. In addition, when applied to the bathymetric data, the channel, which composed to the mixed sediment, made a role of limited factor which characterized to benthic community. Because the specimen around the channel have been affected on the diverse sediment mixture. Most of benthic studies in the southern coast of Korea focused to the condition of benthic organic pollution spatially, because along the coast, it also developed a aquaculture ground and industrial complex. But, as results, most of the area, it turn out the less polluted areas nevertheless similar environment situation. It supposed that benthic community affect to the bottom sediment composition by physical characteristics.

• IMMUNE NETWORK
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• v.5 no.3
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• pp.150-156
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• 2005

Background: Dendritic cells (DCs) playa critical role not only in the initiation of immune responses, but also in the induction of immune tolerance. In an effort to regulate immune responses through the modulation of antigen presenting cell (APC) function of DCs, we searched for and characterized APC function modulators from natural products. Methods: DCs were cultured in the presence of propolis components, WP and CP, and then examined for their ability to present exogenous antigen in association with major histocompatibility complexes (MHC). Results: WP and CP inhibited class I MHC-restricted presentation of exogenous antigen (cross-presentation) in a DC cell line, DC2.4 cells, and DCs generated from bone marrow cells with GM-CSF and IL-4. The inhibitory activity of WP and CP appeared to be due not only to inhibition of phagocytic activity of DCs, but also to suppression of expression of MHC molecules on DCs. We also examined the effects of WP and CP on T cells. Interestingly, WP and CP increased IL-2 production from T cells. Conclusion: These results demonstrate that WP and CP inhibit MHC-restricted presentation of exogenous antigen through down-regulation of phagocytic activity and suppression of expression of MHC molecules on DCs.

• Journal of Digital Convergence
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• v.15 no.6
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• pp.377-383
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• 2017

In this thesis, Improvisation of Jazz Vocal that can be characterized as Jazz music, namely practice of Scat suggest that way of applied approach that root position of chord and chord tones. Scat plays a solo using reproduced tunes of meaningless scat syllable that is not use the lyrics and melodies, which are written in a score. For this, Using the root position of chord is a reference point that Jazz vocal constructs a musical melody. Singing person can develop that reference point from simple scat to develop increasingly complex scat and can express that musical expression and communion. It analyzed the music functionally with a standard Jazz music 'All of me' as the center from composition of chord tone that improvise song to bass line, bass scat, analysis of chord tones arpeggio and expression. In this thesis, the improvisation of a Jazz vocal that may seem somewhat abstruse and complex could be relatively easy to construct through a gradual approach.

• Journal of the Korean Home Economics Association
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• v.38 no.1
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• pp.25-38
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• 2000

This study focuses on the Russian Constructivist Textile Design in the post-revolutionary period, of the early 20th century. Russian textile of the time is highly valued in the west in terms of innovative changes in aesthetic directions, which has become one of the most important centers for the development of new textiles, or the origin of industrial design. Most of brilliant mass-production patterns were produced specially by the pioneers of constructivists such as Stepanova and Popova who were influenced by 'Maxism' through the Revolution regarded themselves as productivists for the proletariat. They were inspired by the avant-garde movements, which were involved with traditionalism, futuristic mechanism, stylization of nature, pure geometrical and abstract form. Early textile design was based on the relationship between the graphic methods of design and the technology because they regarded art as physical, intellectual and technical production. They created all the excitement made from the primary simplest forms of precise mathmatical shapes, such as the circle, the triangle, the rectangle and horizontle and vertical lines. These geometric design can be interpreted as the mechanization of the artists'labor, or methods in line with the technology of mass production, however partly roots in the rich tradition of Russian decorative art. On the other hand, stable crystalline construction on the surface reflect urban architectural complex, and the world of industry in graphic form. They were interested in illusion of movement, cinematic movement of vertical linear rhythms, optical formations and vibrations, by composing a multi-leveled constructions by several spatial planes, or color-field, and combining structures of several intersecting matrices, and superimposing parts of the forms on each other. All these characteristics of the Russian textile designs reflect the complex interactions between 'art and society' of Constructivist's idea and represent the traits of the epoch.

• Journal of Environmental Science International
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• v.20 no.12
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• pp.1553-1560
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• 2011

The study analyzes groundwater balance with regard to the water recharge and discharge which contain urbanization components in Suyeong-gu, Busan. It also verifies the reliability and accuracy improvement on the analysis of the balance. The result of the study is viewed as preliminary data which are useful to develop, utilize and manage groundwater. The average quantity of groundwater recharge is 6,014.1 $m^3$/day in the research area during the last ten year period(from 1998 to 2007). The outflow from drainage areas to rivers and coasts is 149.3 $m^3$/day, the inflow from rivers and coasts to drainage area is 439.9 $m^3$/day. The use of the water is 4,243.0 $m^3$/day. The outflow caused by subway in line No.2 and No.3 through Suyeong-gu and the one by building an underground electric complex is 1,500.0 $m^3$/day. The leakage of water works is 6514.9 $m^3$/day. The inflow and outflow of sewerage is 5082.2 $m^3$/day from groundwater to sewer. The amount of groundwater recharge, the inflow from rivers and coasts to drainage area, and the leakage of water works belong to the amount of groundwater inflow and the total amount is 12,968.9 $m^3$/day. The amount of outflow from drainage area to rivers and coasts, the use of groundwater, outflow by subway and underground electric complex tunnel and the amount of inflow of the water to sewerage belong to the amount of outflow of groundwater and the sum amount is 13,031.5 $m^3$/day. The gap between the amount of inflow and outflow of groundwater is 62.6 $m^3$/day, which is considered to reflect the trend that the short term drop in the amount of rainfall results in the amount of groundwater recharge and that the amount of outflow from drainage area to rivers and coasts decreases.

• Journal of Advanced Navigation Technology
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• v.18 no.4
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• pp.359-363
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• 2014

This paper presents the design and performance of an unequal divider with physical separation and electrical isolation. This divider has a series $18{\Omega}$ resistor and 0.7 pF capacitor circuit between two quarter-wave transmission lines at half phase angle from input terminal. This design method was improved a physical isolation between output ports and easy connected other circuit because of unnecessary of extra transmission line. To show the validity of the unequal divider with complex isolation components, a 4:1 ratio unequal divider was designed and measured at center frequency of 2 GHz. The measured divider performances have the return loss of 17 dB, insertion loss of 1.5 dB and 7.7 dB, and isolation of 18 dB. Its performance is in good agreement with the simulated results.

• Journal of the Korean Society of Costume
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• v.27
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• pp.163-171
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• 1996

As the current stage of the fashion begins to follow the styles of the past the study on he past costume is getting more importance and as the methodology of the study the accurately ap-proached study through the rehabilitation of the past costume is more needed than the simple re-arrangement of the historical documents. By this methodology this study can be positioned as a re-creation activity. The results of the study are as follows. 1) Style: The S-line silhouette remains be-cause of the straight silhouette or the blossom style bodice. This dress has various types of sil-houette but generally it forms one silhouette and is one-piece. 2) color and Material: The material varies hile the color is divided as the main color of ivory and the stress color of brown. This shows not only that the material has been varied but also that they tried to reduce the monotony. 3) Pattern and Sewing: The simple external figure and the previous stage typically shows the movement to the simplicity of the contemporary and the num-ber of patterens is plenty and the sewing method is also complex. 4) Detail. To overcome the simplicity of the style and to show the characteristics of the afternoon dress the skunk fur the net the sash, and the bow are used. 5) Structural Characteristics: The front open-ing the back opening and the side opening coexists in one-pieced dress and this forms unique structure and complex fastening device. The ribbon tape and casing not only finish the seam but also fix the shape of the dress. Synthetically the 1913-14 afternoon dress has the characteristics of transitional stage in which the characteristics of the costume of 1910s and the remnants of the characteristics of the pre-vious costume style and shows the character-istics of afternoon dress well in terms of the ma-terial the structure and the detail.