• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2012년도 정기총회 및 춘계학술발표회
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• pp.20-20
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• 2012

Isoprenoids represent the most diverse group of metabolites, which are functionally and structurally identified in plant organism to date. Ginsenosides, glycosylated triterpenes, are considered to be the major pharmaceutically active ingredient of ginseng. Its backbones, categorized as protopanaxadiol (PPD), protopanaxatriol (PPT), and oleanane saponin, are synthesized via the isoprenoid pathway by cyclization of 2,3-oxidosqualene mediated with dammarenediol synthase or beta-amyrin synthase. The rate-limiting 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), which is the first committed step enzyme catalyzes the cytoplasmic mevalonate (MVA) pathway for isoprenoid biosynthesis. DXP reductoisomerese (DXR), yields 2-C-methyl-D-erythritol 4-phosphate (MEP), is partly involved in isoprenoid biosynthesis via plastid. Squalene synthase and squalene epoxidase are involved right before the cyclization step. The triterpene backbone then undergoes various modifications, such as oxidation, substitution, and glycosylation. Here we will discuss general biosynthesis pathway for the production of ginsenoside and its modification based on their subcellular biological functions.

• 한국경영과학회지
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• 제23권3호
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• pp.135-151
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• 1998

The demand of large capacity in coming cellular systems makes inevitable the deployment of small cells, rendering more frequent handoff occurrences of calls than in the conventional system. The key issue is then how effectively to reduce the chance of unsuccessful handoffs, since the handoff failure is less desirable than that of a new call attempt. In this study, we consider the control policies which give priority to handoff calls by limiting channel assignment for the originating new calls, and allow queueing the new calls which are rejected at their first attempts. On this system. we propose the problem of finding an optimal call control strategy which optimizes the objective function value, while satisfying the requirements on the handoff/new call blocking probabilities and the new call delay. The objective function takes the most general form to include such well-known performance measures as the weighted average carried traffic and the handoff call blocking probability. The problem is formulated into two different linear programming (LP) models. One is based on the direct employment of steady state equations, and the other uses the theory of semi-Markov decision process. Two LP formulations are competitive each other, having its own strength in the numbers of variables and constraints. Extensive experiments are also conducted to show which call control strategy is optimal under various system environments having different objective functions and traffic patterns.

• 전력전자학회논문지
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• 제20권4호
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• pp.297-304
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• 2015

A conventional single-phase high-power system typically generates a large AC line input current at universal 90 VAC condition. Sometimes, this phenomenon can block the Earth Leakage Circuit Breaker (ELCB), which causes problems. Replacing power facilities is essential to ensure smooth operations. Thus, this paper proposes a method that can drive higher power than the limit of conventional power facilities. The proposed method can reduce the large AC line input current by limiting the input power of Power Factor Correction (PFC). An additional battery circuit can supplement the power deficiency. Specifically, a bidirectional converter with charging and discharging functions was adopted for the battery circuit. Finally, the validity of the proposed system could be confirmed by modal analysis and simulation, and an experiment in 2 KW condition was implemented with a prototype sample as well.

• BMB Reports
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• 제41권8호
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• pp.581-586
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• 2008

The pre-replication complex (pre-RC), including the core hexameric MCM2-7 complex, ensures that the eukaryotic genome is replicated only once per cell division cycle. In this study, we identified a rice $\underline{m}ini\underline{c}hromosome$ $\underline{m}aintenance$ (MCM) homologue (OsMCM2) that functionally complemented fission yeast MCM2 (CDC19) mutants. We found OsMCM2 transcript expression in roots, leaves, and seeds, although expression levels differed slightly among the organs. Likewise, the OsMCM2 protein was ubiquitously expressed, but it was downregulated when nutritients were limiting, indicating that MCM2 expression (and therefore cell cycle progression) requires adequate nutrition. Yeast two-hybrid and GST pull-down assays demonstrated that OsMCM2 interacted with the COP9 signalosome 5 (CSN5). Taken as a whole, our results indicated that OsMCM2 functions as a subunit of the rice MCM complex and interacts with CSN5 during developmental regulation.

• Wind and Structures
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• 제18권1호
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• pp.1-20
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• 2014

Modern design of long suspension bridges must satisfy at the same time spanning very long distances and limiting their response against several external loads, even if of high intensity. Structural Control, with the solutions it provides, can offer a reliable contribution to limit internal forces and deformations in structural elements when extreme events occur. This positive aspect is very interesting when the dimensions of the structure are large. Herein, an updated numerical model of an existing suspension bridge is developed in a commercial finite element work frame, starting from original data. This model is used to reevaluate an optimization procedure for a passive control strategy, already proven effective with a simplified model of the buffeting wind forces. Such optimization procedure, previously implemented with a quasi-steady model of the buffeting excitation, is here reevaluated adopting a more refined version of the wind-structure interaction forces in which wind actions are applied on the towers and the cables considering drag forces only. For the deck a more refined formulation, based on the use of indicial functions, is adopted to reflect coupling with the bridge orientation and motion. It is shown that there is no variation of the previously identified optimal passive configuration.

• Structural Engineering and Mechanics
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• 제38권2호
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• pp.171-193
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• 2011

One of the possible alternatives of simulation-based time-dependent reliability assessment of pre-stressed biconcave and biconvex cable trusses, the Monte Carlo method, is applied in this paper. The influence of an excessive deflection of cable truss (caused by creep of cables and rheologic changes) on its time-dependent serviceability is investigated. Attention is given to the definition of the basic random variables and their statistical functions (basic, mutually dependent random variables such as the pre-stressing forces of the bottom and top cable, structural geometry, the Young's modulus of elasticity of the cables, and the independent variables, such as permanent load, wind, snow and thermal actions). Then, the determination of the response of the cable truss to the loading effects, and the definition of the limiting values considering serviceability of the structure are performed. The potential of the method, using direct Monte Carlo technique for simulation-based time-dependent reliability assessment as a powerful tool, is emphasized. Results obtained by the First order reliability method (FORM) are compared with those obtained by the Monte Carlo simulation technique.

• 조명전기설비학회논문지
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• 제26권10호
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• pp.81-88
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• 2012

Surge protective devices(SPDs) are widely used as a most effective means protecting the electrical and electronic equipment against overvoltages such as lightning and switching surges. When installing SPDs, it is essential that the voltage protection level provided by SPDs should be lower than the withstand voltage of the equipment being protected. But even the proper selection of SPDs are achieved, the voltage at the equipment terminal may be higher than the residual voltage of SPD due to the reflection and oscillation phenomena. This paper was focused on the investigations of the conditions for which the equipment is protected by an SPD taking into account the influences of the protective distance and type of load. The protective effects of SPD with voltage-limiting component were analyzed as functions of types of load and protective distance between the SPD and load. As a result, in the cases of long protective distances, capacitive loads and loads with high resistance, the voltage at the load terminal was significantly higher than the residual voltage of SPD. It was found that the proper installation of SPDs should be carried out by taking into account the protective distance and type of load to achieve reliable protection of electronic equipments against surges.

• 한국정보통신학회논문지
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• 제8권3호
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• pp.586-597
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• 2004

MAC (Medium Access Control) protocol is necessary for a OLT (Optical Line Termination) to allocate bandwidth to ONUs (Optical Network Units) dynamically in ATM PON (Passive Optical Network) operated in a kind of optical subscriber network having tree topology. The OLT collect information about ONUs and provide all permission with each ONU effectively by means of MAC protocol. Major functions of MAC protocol are composed of the algorism for distributing permission demanded by a ONU dynamically and allocation all permission used in APON properly. Sometimes MAC get to be a element of limiting the whole operation speed and occupy a most frequent operation part of the TC (Transmission Convergence) function module so it have to be designed to guarantee the best quality for each traffic. This paper introduce the way of implementation of a algorism which satisfy all of the upper renditions. This MAC algorism allocate bandwidth according to a number of working ONU and the information of the queue length dynamically and distribute permission for same interval to minimize delay variation of each ONU cell. MAC scheduler for the dynamic bandwidth allocation which is introduced in this paper has look-up table structure that makes programming possible. This structure is very suitable for implementation and operated in high speed because it require very simple and small chip size.

• The Plant Pathology Journal
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• 제17권2호
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• pp.88-93
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• 2001

Oxidative stress is one of the major limiting factor in plant productivity. Reactive oxygens species (ROS) generated during metabolic processes damage cellular functions and consequently lead to disease, senescence and cell death. Plants have evolved an efficient defense system by which the ROS is scavenged by antioxidant enzymes such as superoxide dismutase (SOD) and ascorbate peroxidase (APX). Attempts to reduce oxidative damages under the stress conditions have included the manipulation of 갠 scavenging enzymes by gene transfer technology. Increased SOD activities of transgenic plants lead to increased resistance against oxidative stresses derived from methyl viologen (MV), and from photooxidative damage caused by high light and low temperature. Transgenic tobacco plants overexpressing APX showed reduced damage following either MV treatment of photooxidative treatment. Overexpression of glutathion reductase (GR) leads to increase in pool of ascorbate and GSH, known as small antioxidant molecules. These results indicate through overexpression of enzymes involved in ROS-scavenging could maintain or improve the plant productivities under environment stress condition. In this study, the rational approaches to develop stress-tolerant plants by gene manipulation of antioxidant enzymes will be introduced to provide solutions for the global food and environmental problems in the $21^\textrm{st}$ century.

• 한국소음진동공학회논문집
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• 제18권12호
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• pp.1262-1269
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• 2008

Though multilayered foam-panel structures have been widely used to reduce sound transmission in various fields, most of the previous works to design them were conducted by repeated analyses or experiments based on initially given configurations or sequences. Therefore, it was difficult to obtain an optimal sequence of multilayered foam-panel structure yielding superior sound isolation capability. In this work, we propose a new design method to sequence a multi-panel structure lined with a poroelastic material having maximized sound transmission loss. Being formulated as a one-dimensional topology optimization problem fur a given target frequency, the optimal sequencing of panel-poroelastic layers is systematically carried out in an iterative manner. In this method, a panel layer is expressed as a limiting case of a poroelastic layer to facilitate the optimization process. This means that main material properties of a poroelastic material are treated as interpolated functions of design variable. The designed sequences of panel-poroelastic multilayer were shown to be significantly affected by the target frequencies; more panels were obtained at higher target frequency. The sound transmission loss of the system was calculated by the transfer matrix derived from Biot's theory.