• Tuberculosis and Respiratory Diseases
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• v.82 no.4
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• pp.348-356
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• 2019

Background: Recently, the number of lung transplants in South Korea has increased. However, the long-term outcome data is limited. In this study, we aimed to investigate the long-term outcomes of adult lung transplantation recipients. Methods: Among the patients that underwent lung transplantation at a tertiary referral center in South Korea between 2008 and 2017, adults patient who underwent deceased-donor lung transplantation with available follow-up data were enrolled. Their medical records were retrospectively reviewed. Results: Through eligibility screening, we identified 60 adult patients that underwent lung (n=51) or heart-lung transplantation (n=9) during the observation period. Idiopathic pulmonary fibrosis (46.7%, 28/60) was the most frequent cause of lung transplantation. For all the 60 patients, the median follow-up duration for post-transplantation was 2.6 years (range, 0.01-7.6). During the post-transplantation follow-up period, 19 patients (31.7%) died at a median duration of 194 days. The survival rates were 75.5%, 67.6%, and 61.8% at 1 year, 3 years, and 5 years, respectively. Out of the 60 patients, 8 (13.3%) were diagnosed with chronic lung allograft dysfunction (CLAD), after a mean duration of $3.3{\pm}2.8years$ post-transplantation. The CLAD development rate was 0%, 17.7%, and 25.8% at 1 year, 3 years, and 5 years, respectively. The most common newly developed post-transplantation comorbidity was the chronic kidney disease (CKD; 54.0%), followed by diabetes mellitus (25.9%). Conclusion: Among the adult lung transplantation recipients at a South Korea tertiary referral center, the long-term survival rates were favorable. The proportion of patients who developed CLAD was not substantial. CKD was the most common post-transplantation comorbidity.

• Journal of Korea Water Resources Association
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• v.52 no.5
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• pp.337-347
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• 2019

This study proposes the framework to select the representative general circulation model (GCM) for climate change projection. The grid-based results of GCMs were transformed to all considered meteorological stations using inverse distance weighted (IDW) method and its results were compared to the observed precipitation. Six quantile mapping methods and random forest method were used to correct the bias between GCM's and the observation data. Thus, the empirical quantile which belongs to non-parameteric transformation method was selected as a best bias correction method by comparing the measures of performance indicators. Then, one of the multi-criteria decision techniques, TOPSIS (Technique for Order of Preference by Ideal Solution), was used to find the representative GCM using the performances of four GCMs after the bias correction using empirical quantile method. As a result, GISS-E2-R was the best and followed by MIROC5, CSIRO-Mk3-6-0, and CCSM4. Because these results are limited several GCMs, different results will be expected if more GCM data considered.

• Journal of Korean Classical Literature and Education
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• no.15
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• pp.329-353
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• 2008

Tasan Jeong Yak-yong is great scholar, who makes a synthesis of Sil-hak[實學, Practical Science of Korea], reformer of society, and a poet in the Joseon Dynasty. He expressed contradiction and conflict of those days by intellectual language, and reperceived basic ideology of the Joseon society. Also he theorized dissatisfaction of the people about those days and its system as form of religion. We can divide Tasan's life into two times. The first part is his ages 16~39 in the period of Jeong-jo(1777~1800). The second part is in the period of Sun-jo(1801~1834). In this period, he was exiled into Gang-jin for 17 years. After banishment, he lived a quiet life for the rest of his life in his hometown. His allegoric poetry were written in this second period. The special feature of allegoric poetry is strong satire. An allegory would be that is 'king's ear', which the barber has sight, or the barber's voice, which has divulged king's secret among the bamboos. Otherwise it would be that is the sound 'king's ear is donkey's ear' in the bamboos. This sound is divulging of the true donkey's ear. It doesn't travel to audiences, but travels trough wind in the bamboos. The narration exists just as story that barber can't stand to keep silence about king's secret. There are exposure of true and critical motive as allegoric expression. Tasan's allegoric poetry stand on the basis of his love for the people. Also there reveals his thought deeply with an enormous amount of reading and self-communion. Moreover there are his warm mind with his sharp insight in which captures alive lives as allegoric materials. Most of allegoric poetry satirize actuality of those days to make an excuse for external distinguishing marks of animals and plants. However Tasan's poetry are different from them. After he grasped serious problems from his contemporary actuality, and then choosed allegoric media to express correctly. Because he grasped the special features of lives after minute observation, he could exposure controversial point of the actual. His sharp insight was not limited to allegoric media. He noticed his period and the current of his society sensitively. It made his allegoric poetry as important materials to make us to know the condition of the people in the Joseon Dynasty. Tasan's allegoric poetry is inherited by Baek Seok[白石, 1912~1995] as regular juvenile literature. Baek Seok's juvenile stories are the results of expansion and transition for Tasan's allegoric poetry. Allegoric poetry was the shout of barber to prosecute about social irregularities and contradiction, and the sound of the bamboos to travel moaning of the people in the past. Now allegoric poetry create new emotion to make us to speculate ourselves with our surrounding. This changes are caused by special feature of allegoric poetry as a form to reflect our general lives.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.1
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• pp.9-16
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• 2021

Under the stressed condition, a complex feedback mechanism for stress is activated to maintain homeostasis of the body and secretes several stress hormones. But these stress hormones impair synthesis and secretion of the reproductive hormones, followed by suppression of ovarian function. Cytochrome P450 1A2 (CYP1A2) plays a major role in metabolizing exogenous substances and endogenous hormones, and its expression is recently identified at not only the liver but also several organs with respect to the pancreas, lung and ovary. Although the expression of CYP1A2 can be also affected by several factors, understanding for the changed pattern of the ovarian CYP1A2 expression upon stress induction is still limited. Therefore, CYP1A2 expression in the ovaries from immobilization stress-induced rats were assessed in the present study. The stress-induced rats in the present study exhibited the physiological changes in terms of increased stress hormone level and decreased body weight gains. Under immunohistological observation, the ovarian CYP1A2 expression in both control and the stressed ovary was localized in the antral to pre-ovulatory follicles. However, its expression level was significantly (p < 0.01) higher in the stress-induced group than control group. In addition, stress-induced group presented more abundant CYP1A2-positive follicles (%) than control group. Since expression of the ovarian CYP1A2 was highly related with follicle atresia, increased expression of CYP1A2 in the stressed ovary might be associated with changes of the ovarian follicular dynamics due to stress induction. We hope that these findings have important implications in the fields of the reproductive biology.

• Journal of Wetlands Research
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• v.23 no.2
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• pp.154-162
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• 2021

The naturally opened Han river estuary is a place where the flows of the Han river, Imjin river, Yaesung river meet with West Sea of Korea, so the hydrodynamic mechanism(Impact-Response) structure of Han river estuary is complex. Continuous observation and measurement due to the morphological characteristics at the estuary are required to maintain the estuary environment and river management facilities. However, the Sannam wetland(the study area) is in the military operation area. Therefore, Sannam wetland has the limited access under the control from military office. In 2020, there had a natural disaster due to flooding in August and COVID-19, and it made a survey hard. The noncontact survey technique, the analysis of LANDSAT images at Sannam wetland, was applied to analyze riverbed fluctuation and morphological transformation around Sannam wetland. LANDSAT images obtained from EarthExplorer, USGS and analyzed by QGIS. The analysis was performed based on the area and the distance near Sannam wetland. As a result, an erosion was happened on the downstream of the study area, and the upstream of the study area did not have any serious sediment transport. Considering the resolution of LANDSAT images, this noncontect survey technique is applicable to manage the study area. From the analysis of LANDSAT images, it is assumed that the tidal effect is greater than the inflow from the upstream. The pattern change of tidal response causes the damage of the river facilities near the Hangang river estuary.

• Journal of Korean Elementary Science Education
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• v.41 no.2
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• pp.267-282
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• 2022

This study aims to analyze the continuity and sequence between the intelligent life curriculum for grades 1-2 and the science curriculum for grades 3-4 with a focus on knowledge and inquiry process skills. The results demonstrate that contents related to science in the intelligent life curriculum consisted of only 10 out of 32 elements. Five elements were related to the science curriculum for grades 3-4 and limited to the 'life sciences' area. Particularly, the intelligent life curriculum did not address topics related to 'matter' and 'motion and energy'. Developmental connection was established in the 'life sciences' area and dramatic changes were noted for the topics related to 'earth and space' area. In terms of inquiry process skills, the levels of observation, measurement, inference, and communication naturally increased, whereas a developmental connection was noted between the intelligent life and science curricula. Classification can be viewed as a developmental link; however, viewing the classification as scientific from the epistemic perspectives was insufficient. In the case of expectation, a gap was observed in both curricula due to the absence of expectation activities in the intelligent life curricula. The study discussed the implications for securing the connection between the intelligent life and science curricula on the basis of these results.

• Journal of Space Technology and Applications
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• v.2 no.1
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• pp.41-51
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• 2022

CubeSat is a satellite platform that is widely used not only for earth observation but also for space exploration. CubeSat is also used in magnetic field investigation missions to observe space physics phenomena with various shape configurations of magnetometer instrument unit. In case of magnetic field measurement, the magnetometer instrument should be far away from the satellite body to minimize the magnetic disturbances from satellites. But the accommodation setting of the magnetometer instrument is limited due to the volume constraint of small satellites like a CubeSat. In this paper, we investigated that the magnetic field interference generated by the cube satellite was analyzed how much it can affect the reliability of magnetic field measurement. For this analysis, we used a reaction wheel and Torque rods which have relatively high-power consumption as major noise sources. The magnetic dipole moment of these parts was derived by the data sheet of the manufacturer. We have been confirmed that the effect of the residual moment of the magnetic torque located in the middle of the 3U cube satellite can reach 36,000 nT from the outermost end of the body of the CubeSat in a space without an external magnetic field. In the case of accurate magnetic field measurements of less than 1 nT, we found that the magnetometer should be at least 0.6 m away from the CubeSat body. We expect that this analysis method will be an important role of a magnetic cleanliness analysis when designing a CubeSat to carry out a magnetic field measurement.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.3
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• pp.343-350
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• 2022

High-resolution data are needed to understand water body mixing patterns at river junctions. In particular, in river analysis, hydrological and water quality characteristics are used as basic data for aquatic ecological health, so observation through continuous monitoring is necessary. In addition, since measurement is carried out through a one-dimensional and fixed measurement method in existing monitoring systems, a hydrological and water quality characteristics investigation of an entire river, except for in the immediate vicinity of the measurement point, is not undertaken. In order to obtain high-resolution measurement data, a measurer has to consider multiple factors, and the area or time that can be measured is limited. Although the resolution might be lowered, an appropriate interpolation method must be selected in order to acquire a wide range of data. Therefore, in this study, a high-elevation measurement method at a river junction was introduced, and the interpolation method according to the measurement results was compared. The overall hydraulic and water quality information of the river was indicated through the visualization of the prediction and interpolation method in the low-resolution measurement result. By comparing each interpolation method, Inverse Distance Weighting, Natural Neighbor, and Kriging techniques were applied in river mapping to improve the precision of river mapping through visualized data and quantitative evaluation. It is thought that this study will offer a new method for measuring rivers through spatial interpolation.

• Korean Journal of Ecology and Environment
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• v.55 no.4
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• pp.368-375
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• 2022

Gut contents analysis is essential to predict the impact of organisms on food source changes due to variations of the habitat environment. Previous studies of gut content analysis have been conducted using traditional methods, such as visual observation. However, these studies are limited in analyzing food sources because of the digestive process in gut organ. DNA metabarcoding analysis is a useful method to analyze food sources by supplementing these limitations. We sampled marine fish of Pennahia argentata, Larimichthys polyactis, Crangon affinis, Loligo beka and Sepia officinalis from Gwangyang Bay and Yeosu fisheries market for analyzing gut contents by applying DNA metabarcoding analysis. 18S rRNA v9 primer was used for analyzing food source by DNA metabarcoding. Network and two-way clustering analyses characterized the relationship between organisms and food sources. As a result of comparing metabarcoding of gut contents for P. argentata between sampled from Gwangyang Bay and the fisheries market, fish and Copepoda were analyzed as common food sources. In addition, Decapoda and Copepoda were analyzed as common food sources for L. polyactis and C. affinis, respectively. Copepoda was analyzed as the primary food source for L. beka and S. officinalis. These study results demonstrated that gut contents analysis using DNA metabarcoding reflects diverse and detailed information of biological food sources in the aquatic environment. In addition, it will be possible to provide biological information in the gut to identify key food sources by applying it to the research on the food web in the ecosystem.

• Journal of Space Technology and Applications
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• v.3 no.1
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• pp.26-43
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• 2023

As Korean first lunar probe, Danuri, succeeded in entering lunar orbit, Korean new space exploration plans such as Mars exploration can be expected. Korean space exploration payload is developed only in a limited field, so there is a need to create a new space exploration payload. In foreign countries, there is a mass spectrometer as a basic equipment for space exploration, and it is a very useful payload that encompasses the exploration of life through the analysis of organic matter as well as the observation of the atmosphere and volatile substances of the exploration target. However, Korea has never developed a mass spectrometer payload for space exploration, so it is necessary to secure technology in preparation for future space exploration. Before that, we look at the scientific achievements of foreign mass spectrometer payloads for space exploration and identify trends.