• Journal of the Society of Naval Architects of Korea
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• v.57 no.3
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• pp.175-181
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• 2020

For the success of a structural integrity management, it is essential to acquire structural response data at some critical locations with limited number of sensors. In this study, the structural response of numerical model was estimated by data fusion approach based on the Kalman filter known as stochastic recursive filter. Firstly, transient direct analysis was conducted to calculate the acceleration and strain of the numerical standing beam model, then the noise signals were mixed to generate the numerical measurement signals. The acceleration measurement signal was provided to the Kalman filter as an information on the external load, and the displacement measurement, which was transformed from the strain measurement by using strain-displacement conversion relationship, was provided into the Kalman filter as an observation information. Finally, the Kalman filter estimated the displacement by combining both displacements calculated from each numerically measured signal, then the estimated results were compared with the results of the transient direct analysis.

• Perspectives in Nursing Science
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• v.8 no.2
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• pp.139-147
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• 2011

Purpose: An integrative literature review was done to identify the best interventions for older adults with dyslipidemia in an effort to promote nursing involvement in the prevention of statin-induced symptoms (SIS). Such awareness could increase the capacity of interventions by geriatric nurses using evidence-based practices in the reassessment of statin therapy. Methods: CINAHL, Pubmed, and ProQuest were searched using these terms: dyslipidemia in, elderly, statins, adverse effects, and quality of life. Eleven articles fitting the inclusion criteria were identified and analyzed. Results: The findings indicate no evidence for the benefit of statin therapy for morbidity/mortality in a high-risk primary prevention set-up, specifically in the elderly population. Although SIS prevails among older adults, there are limited data that confidently support this observation along with nursing interventions specifically for the geriatric nursing community. Conclusion: Future research is necessary to shift nursing intervention with statin users (specifically in older adults) from an illness-based intervention to a preventive care plan to provide optimal care based on evidence. It is essential to involve self-reporting, cooperation, and communication with health care professionals, specifically with geriatric nurses. Additional studies are needed to further direct practice interventions in elderly statin users.

• Proceedings of the Korean Geotechical Society Conference
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• 2002.03a
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• pp.63-70
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• 2002

In tunnel construction, the information on the rock quality and the location of fault or fracture are crucial for economical design of support pattern and for safe construction of the tunnel. The grade of rock is commonly estimated through the observation with the naked eye of recovered cores in drilling or from physical parameters obtained by their laboratory test. Since drilling cost is quite expensive and terrains of planned sites for tunnel construction are rough in many cases, however, only limited information could be provided by core drilling Electrical resistivity and EM surveys may be a clue to get over this difficulty. Thus we have investigated electrical resistivity and EM field data providing regional Information of the rock Quality and delineating fault and fracture over a rough terrain. In this paper, we present some case histories using electrical resistivity and EM survey for the site investigation of tunnel construction. Through electrical resistivity and EM survey, the range and depth of coal seam was clearly estimated, cavities were detected in limestone area, and weak zones such as joint, fault and fracture have been delineated.

• Applied Microscopy
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• v.5 no.1
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• pp.1-8
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• 1975

These studies were carried out the observation of polymorphonuclear leukocyte phagocytosis of Candida albicans in vitro and also detected to the cytoplasmic changes of polymorphonuclear leukocyte during phagocytosis by the method of electron microscopy. The results were summarized as follows: 1. In normal polymorphonuclear leukocyte, nuclear lobes showed a preponderance of dense, granular chromatin located peripherally. The cytoplasm of polymorphonuclear leukocyte was not extensive; the cytoplasmic matrix was moderate dense and of a granular appearance. Golgi complex and rough endoplasmic reticulum system was poorly developed. But a various type of granules were seen abundantly. 2. After 30 minutes of incubation, Candida albicans was completely engulfed. These had come to lie in the vacuole which was limited by the membrane. 3. After 90 minutes of incubation, the phagocytic vacuoles were larger, and many granules devoid of membranes were seen within them. Though the granules has lost their membrane after entering the vacuoles. 4. After 2 hours of incubation, the cytoplamsic components of polymorphonuclear leuko cytes were changed their original morphology.

• Toxicological Research
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• v.27 no.4
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• pp.217-224
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• 2011

The object of this study was to evaluate the single oral dose toxicity of platycodin D, a saponin from the root of Platycodon grandiflorum in male and female mice. Platycodin D was administered to female and male mice as an oral dose of 2000, 1000, 500, 250 and 125 mg/kg (body wt.). Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after treatment, upon necropsy, organ weight and histopathology of 14 principle organs were examined. As the results, no platycodin D treatment related mortalities, clinical signs, changes on the body and organ weights, gross and histopathological observations against 14 principle organs were detected up to 2000 mg/kg in both female and male mice. Therefore, $LD_{50}$ (50% lethal dose) and approximate LD of playtcodin D after single oral treatment in female and male mice were considered over 2000 mg/kg - the limited dosages recommended by KFDA Guidelines [2009-116, 2009], respectively.

• Journal of the Korean Applied Science and Technology
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• v.27 no.3
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• pp.282-289
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• 2010

In preparation of silica aerogel-based hybrid coating materials, the combination of hydrophobic aerogel with organic polar binder material is shown to be very limited due to dissimilar surface property between two materials. Accordingly, the surface modification of the aerogel would be required to obtain compatibilized hybrid coating sols with homogeneous dispersion. In this study, the surface of silica aerogel particles was modified by using both surfactant adsorption and heat treatment methods. Four types of surfactants with different molecular weights and HLB values were used to examine the effect of chain length and hydrophilicity. The surface property of the modified aerogel was evaluated in terms of visible observation for aerogel dispersion in water, water contact angle measurement, and FT-IR analysis. In surface modification using surfactants, the effects of surfactant type and content, and mixing time as process parameter on the degree of hydrophilicity for the modified aerogel. In addition, the temperature condition in modification process via heat treatment was revealed to be significant factor to prepare aerogel with highly hydrophilic property.

• Korean Journal of Metals and Materials
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• v.48 no.8
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• pp.717-723
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• 2010

The degradation behavior of fuel cladding is a very import concern in nuclear power generation, because the operation of nuclear plants can be limited by fuel cladding degradation. In order to evaluate the hydride effect on failure of zirconium fuel claddings, a ring tensile test for the circumferential direction was carried out at room temperature for claddings having different hydride characteristics such as density and orientation; microstructural evaluation was also performed for those claddings. The circumferential failure of the claddings was promoted by increasing the hydride concentration in the matrix; however, the failure of the claddings was affected by the hydride orientation rather than by the hydride concentration in the matrix. From fracture surface observation, the cladding failure during the ring tensile test was matched with the hydride orientation.

• Mycobiology
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• v.47 no.3
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• pp.319-328
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• 2019

Cytospora is a genus including important phytopathogens causing severe dieback and canker diseases distributed worldwide with a wide host range. However, identification of Cytospora species is difficult since the currently available DNA sequence data are insufficient. Aside the limited availability of ex-type sequence data, most of the genetic work is only based on the ITS region DNA marker which lacks the resolution to delineate to the species level in Cytospora. In this study, three fresh strains were isolated from the symptomatic branches of Elaeagnus angustifolia in Xinjiang Uygur Autonomous Region, China. Morphological observation and multi-locus phylogenetic analyses (ITS, LSU, ACT and RPB2) support these specimens are best accommodated as a distinct novel species of Cytospora. Cytospora elaeagnicola sp. nov. is introduced, having discoid, nearly flat, pycnidial conidiomata with hyaline, allantoid conidia, and differs from its relatives genetically and by host association.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.1
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• pp.28-40
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• 2014

Objectives: This study was to evaluate the single dose toxicity of Sobokchuko-tang (SBC) in male and female mice. Methods: Aqueous extract of SBC (yield=6.60%) was administered to female and male mice as an oral dose of 2,000, 1,000 and 500 mg/kg (body weight) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines. Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after dosing, upon necropsy; organ weight and histopathology of 14 principle organs were also examined. Results: we could not find any SBC treatment related mortality and clinical signs, changes in the body and organ weights, gross findings and changes in histopathology of principle organs, except for pharmacological immunomodulatory effects related findings including significant increases of submandibular lymph node weights, hypertrophy and hyperplasia of lymphoid cells in the submandibular lymph nodes restrictly detected in 2,000 mg/kg treated female and male mice with some sporadic accidental findings. Conclusions: The results obtained in this study suggest that the 50% lethal dose and approximate lethal dose of SBC aqueous extracts in both female and male mice were considered as over 2,000 mg/kg, the limited highest dosage recommended by KFDA Guidelines, and can be safety used in clinics.

• Nuclear Engineering and Technology
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• v.53 no.3
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• pp.776-792
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• 2021

Conventional integral effect test facilities were constructed to enable the precise observation of thermal-hydraulic phenomena and reactor behaviors under postulated accident conditions to prove reactor safety. Although these facilities improved the understanding of thermal-hydraulic phenomena and reactor safety, applications of new technologies and their performance tests have been limited owing to the cost and large scale of the facilities. Various nuclear technologies converging 4th industrial revolution technologies such as artificial intelligence, drone, and 3D printing, are being developed to improve plant management strategies. Additionally, new conceptual passive safety systems are being developed to enhance reactor safety. A new integral effect test facility having a noticeable scaling ratio, i.e., the (UNIST reactor innovation loop (URI-LO), is designed and constructed to improve the technical quality of these technologies by performance and feasibility tests. In particular, the URI-LO, which is constructed using a transparent material, enables better visualization and provides physical insights on multidimensional phenomena inside the reactor system. The facility design based on three-level approach is qualitatively validated with preliminary analyses, and its functionality as a test facility is confirmed through a series of experiments. The design feature, design validation, functionality test, and future utilization of the URI-LO are introduced.