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Nummular Eczema Treated by Hoeyeok-tang Based on the Shanghanlun Disease Pattern Identification Diagnostic System (『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 회역탕(回逆湯) 투여 후 호전된 화폐상 습진 증례 1례)

  • Lim, Eunkyo
    • 대한상한금궤의학회지
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    • v.13 no.1
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    • pp.155-164
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    • 2021
  • Objective: This study aimed to report the improvement of a patient with nummular eczema treated with Hoeyeok-tang based on Shanghanlun provisions. Methods: According to the disease pattern identification diagnostic system (DPIDS) based on the Shanghanlun provisions, the patient was diagnosed with lesser yin disease according to the 324th provision. The patient was treated with Hoeyeok-tang for 90 days. The severity of pruritus decreased, and changes in symptoms were estimated by a visual analog scale, Scoring Atopic Dermatitis Index and the Validated Investigator Global Assessment for Atopic Dermatitis. Results: The patient's symptoms were improved. The severity of pruritus decreased and they recovered from abrasions. Conclusions: This study suggests that the 324th provision of Shanghanlun refer directly to nummular eczema.

High-Performance Schottky Junction for Self-Powered, Ultrafast, Broadband Alternating Current Photodetector

  • Lim, Jaeseong;Kumar, Mohit;Seo, Hyungtak
    • Korean Journal of Materials Research
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    • v.32 no.8
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    • pp.333-338
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    • 2022
  • In this work, we developed silver nanowires and a silicon based Schottky junction and demonstrated ultrafast broadband photosensing behavior. The current device had a response speed that was ultrafast, with a rising time of 36 ㎲ and a falling time of 382 ㎲, and it had a high level of repeatability across a broad spectrum of wavelengths (λ = 365 to 940 nm). Furthermore, it exhibited excellent responsivity of 60 mA/W and a significant detectivity of 3.5 × 1012 Jones at a λ = 940 nm with an intensity of 0.2 mW cm-2 under zero bias operating voltage, which reflects a boost of 50 %, by using the AC PV effect. This excellent broadband performance was caused by the photon-induced alternative photocurrent effect, which changed the way the optoelectronics work. This innovative approach will open a second door to the potential design of a broadband ultrafast device for use in cutting-edge optoelectronics.

Use of Cell-Penetrating Peptides in Dendritic Cell-Based Vaccination

  • Sangho Lim;Ja-Hyun Koo;Je-Min Choi
    • IMMUNE NETWORK
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    • v.16 no.1
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    • pp.33-43
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    • 2016
  • Cell-penetrating peptides (CPPs) are short amino acids that have been widely used to deliver macromolecules such as proteins, peptides, DNA, or RNA, to control cellular behavior for therapeutic purposes. CPPs have been used to treat immunological diseases through the delivery of immune modulatory molecules in vivo. Their intracellular delivery efficiency is highly synergistic with the cellular characteristics of the dendritic cells (DCs), which actively uptake foreign antigens. DC-based vaccines are primarily generated by pulsing DCs ex vivo with various immunomodulatory antigens. CPP conjugation to antigens would increase DC uptake as well as antigen processing and presentation on both MHC class II and MHC class I molecules, leading to antigen specific CD4+ and CD8+ T cell responses. CPP-antigen based DC vaccination is considered a promising tool for cancer immunotherapy due to the enhanced CTL response. In this review, we discuss the various applications of CPPs in immune modulation and DC vaccination, and highlight the advantages and limitations of the current CPP-based DC vaccination.

Influence of Stocking Density with Different Light System on the Growth Performance and Behavior in Broiler Chickens

  • Lim, Chun Ik;Rana, Md Masud;Choi, Il Bok;Ryu, Kyeong Seon
    • Korean Journal of Poultry Science
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    • v.46 no.4
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    • pp.297-304
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    • 2019
  • This study evaluated the effects of stocking density on performance and behavioral activities of 35-day-old broilers in relation to incandescent white bulb (IB) light and LED yellow and white light. A total of 1,650 day-old chicks were weighed and randomly allocated into six treatment groups in a 2 × 3 factorial arrangement based on stocking density (14 birds m-2 and 22 birds m-2) and color of lights (IB; monochromatic LED yellow and white light) with five replicates for each treatment. The results showed that final body weight, weight gain and feed conversion of broilers were improved at a stocking density of 14 birds m-2 with exposure to LED lights. Similarly, broilers spent more time exhibiting inactive behavior (e.g. standing) and active behaviors (e.g. walking and walking plus pecking) under 14 birds m-2 with exposure to lights as compared that of other treatment groups. Regarding a stocking density of 22 birds m-2, broilers performance traits were negatively affected and also activities were less. The performance of broilers was not significantly altered for the main factor of different lights but broilers were less inactive (e.g less time spent sitting plus standing) and more time spent active behavior in walking under IB light than LED light. Thus, we concluded that a stocking density 14 birds m-2 with exposure to LED light significantly improved broiler performance and behavioral activity and these conditions could therefore improve the overall welfare of farmed chickens.

Electro-Optical Properties of AZO Thin Films with Deposition & Heat treatment Conditions (AZO 박막의 증착 및 열처리 조건에 따른 전기·광학적 특성)

  • Yeon, Eung-Beom;Lee, Taek-Yong;Kim, Seon-Tai;Lim, Sang-Chul
    • Korean Journal of Materials Research
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    • v.30 no.10
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    • pp.558-565
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    • 2020
  • AZO thin films are grown on a p-Si(111) substrate by RF magnetron sputtering. The characteristics of various thicknesses and heat treatment conditions are investigated by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Hall effect and room-temperature photoluminescence (PL) measurements. The substrate temperature and the RF power during growth are kept constant at 400 ℃ and 200 W, respectively. AZO films are grown with a preferred orientation along the c-axis. As the thickness and the heat treatment temperature increases, the length of the c-axis decreases as Al3+ ions of relatively small ion radius are substituted for Zn2+ ions. At room temperature, the PL spectrum is separated into an NBE emission peak around 3.2 eV and a violet regions peak around 2.95 eV with increasing thickness, and the PL emission peak of 300 nm is red-shifted with increasing annealing temperature. In the XPS measurement, the peak intensity of Al2p and Oll increases with increasing annealing temperature. The AZO thin film of 100 nm thickness shows values of 6.5 × 1019 cm-3 of carrier concentration, 8.4 cm-2/V·s of mobility and 1.2 × 10-2 Ω·cm electrical resistivity. As the thickness of the thin film increases, the carrier concentration and the mobility increase, resulting in the decrease of resistivity. With the carrier concentration, mobility decreases when the heat treatment temperature increases more than 500 ℃.

SOME Lq INEQUALITIES FOR POLYNOMIAL

  • Chanam, Barchand;Reingachan, N.;Devi, Khangembam Babina;Devi, Maisnam Triveni;Krishnadas, Kshetrimayum
    • Nonlinear Functional Analysis and Applications
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    • v.26 no.2
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    • pp.331-345
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    • 2021
  • Let p(z)be a polynomial of degree n. Then Bernstein's inequality [12,18] is $${\max\limits_{{\mid}z{\mid}=1}}\;{\mid}p^{\prime}(z){\mid}\;{\leq}\;n\;{\max_{{\mid}z{\mid}=1}{\mid}(z){\mid}}$$. For q > 0, we denote $${\parallel}p{\parallel}_q=\{{\frac{1}{2{\pi}}}{\normalsize\displaystyle\smashmargin{2}{\int\nolimits_{0}}^{2{\pi}}}\;{\mid}p(e^{i{\theta}}){\mid}^qd{\theta}\}^{\frac{1}{q}}$$, and a well-known fact from analysis [17] gives $${{\lim_{q{\rightarrow}{{\infty}}}}\{{\frac{1}{2{\pi}}}{\normalsize\displaystyle\smashmargin{2}{\int\nolimits_{0}}^{2{\pi}}}\;{\mid}p(e^{i{\theta}}){\mid}^qd{\theta}\}^{\frac{1}{q}}={\max\limits_{{\mid}z{\mid}=1}}\;{\mid}p(z){\mid}$$. Above Bernstein's inequality was extended by Zygmund [19] into Lq norm by proving ║p'║q ≤ n║p║q, q ≥ 1. Let p(z) = a0 + ∑n𝜈=𝜇 a𝜈z𝜈, 1 ≤ 𝜇 ≤ n, be a polynomial of degree n having no zero in |z| < k, k ≥ 1. Then for 0 < r ≤ R ≤ k, Aziz and Zargar [4] proved $${\max\limits_{{\mid}z{\mid}=R}}\;{\mid}p^{\prime}(z){\mid}\;{\leq}\;{\frac{nR^{{\mu}-1}(R^{\mu}+k^{\mu})^{{\frac{n}{\mu}}-1}}{(r^{\mu}+k^{\mu})^{\frac{n}{\mu}}}\;{\max\limits_{{\mid}z{\mid}=r}}\;{\mid}p(z){\mid}}$$. In this paper, we obtain the Lq version of the above inequality for q > 0. Further, we extend a result of Aziz and Shah [3] into Lq analogue for q > 0. Our results not only extend some known polynomial inequalities, but also reduce to some interesting results as particular cases.

Estimating excess post-exercise oxygen consumption using multiple linear regression in healthy Korean adults: a pilot study

  • Jung, Won-Sang;Park, Hun-Young;Kim, Sung-Woo;Kim, Jisu;Hwang, Hyejung;Lim, Kiwon
    • Korean Journal of Exercise Nutrition
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    • v.25 no.1
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    • pp.35-41
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    • 2021
  • [Purpose] This pilot study aimed to develop a regression model to estimate the excess post-exercise oxygen consumption (EPOC) of Korean adults using various easy-to-measure dependent variables. [Methods] The EPOC and dependent variables for its estimation (e.g., sex, age, height, weight, body mass index, fat-free mass [FFM], fat mass, % body fat, and heart rate_sum [HR_sum]) were measured in 75 healthy adults (31 males, 44 females). Statistical analysis was performed to develop an EPOC estimation regression model using the stepwise regression method. [Results] We confirmed that FFM and HR_sum were important variables in the EPOC regression models of various exercise types. The explanatory power and standard errors of estimates (SEE) for EPOC of each exercise type were as follows: the continuous exercise (CEx) regression model was 86.3% (R2) and 85.9% (adjusted R2), and the mean SEE was 11.73 kcal, interval exercise (IEx) regression model was 83.1% (R2) and 82.6% (adjusted R2), while the mean SEE was 13.68 kcal, and the accumulation of short-duration exercise (AEx) regression models was 91.3% (R2) and 91.0% (adjusted R2), while the mean SEE was 27.71 kcal. There was no significant difference between the measured EPOC using a metabolic gas analyzer and the predicted EPOC for each exercise type. [Conclusion] This pilot study developed a regression model to estimate EPOC in healthy Korean adults. The regression model was as follows: CEx = -37.128 + 1.003 × (FFM) + 0.016 × (HR_sum), IEx = -49.265 + 1.442 × (FFM) + 0.013 × (HR_sum), and AEx = -100.942 + 2.209 × (FFM) + 0.020 × (HR_sum).

Performance Improvement of RRT* Family Algorithms by Limiting Sampling Range in Circular and Spherical Obstacle Environments (샘플링 범위 제한을 이용한 원 및 구 장애물 환경에서의 RRT* 계열 알고리즘 성능 개량)

  • Lee, Sangil;Park, Jongho;Lim, Jaesung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.50 no.11
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    • pp.809-817
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    • 2022
  • The development of unmanned robots and UAVs has increased the need for path planning methods such as RRT* algorithm. It mostly works well in various environments and is utilized in many fields. A lot of research has been conducted to obtain a better path in terms of efficiency through various modifications to the RRT* algorithm, and the performance of the algorithm is continuously improved thanks to these efforts. In this study, a method using the limitation of sampling range is proposed as an extension of these efforts. Based on the idea that a path passing close to obstacles is similar to the optimal path in obstacle environments, nodes are produced around the obstacle. Also, rewiring algorithm is modified to quickly obtain the path. The performance of the proposed algorithm is validated by comparative analysis of the previous basic algorithm and the generated path is tracked by a UAV's kinematic model for further verification.

A Study of Diagnostic Reference Levels for Coronary Angiography and Percutaneous Coronary Intervention in Gyeongsang Area (관상동맥 조영술 및 경피적 관상동맥 중재술에 대한 진단참고준위에 관한 연구; 경상도지역중심)

  • Si-Wang Lim;Jung-Su Kim;Pyong-Kon Cho
    • Journal of radiological science and technology
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    • v.46 no.2
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    • pp.123-129
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    • 2023
  • Interventional cardiology procedures can involve relatively high radiation doses compared to conventional radiography. During CAG, CAG + PCI and PCI the same area is exposed to radiation for a long period. In this study, radiation exposure data of 421 examinations in Gyeongsang area were collected, and the DRLs and ADs in actual medical practice for three types of interventional cardiology procedures in Korea were established. In CAG 286 case, 75th percentile DRLs and ADs of the total DAP were 55.89 Gy·cm2 and 37.47 Gy·cm2 , respectively. In CAG + PCI 92 case, those values were 222.84 Gy·cm2 and 117.51 Gy·cm2 respectively. In PCI 43 case, those values were 198.73 Gy·cm2 and 120.13 Gy·cm2 respectively. In this study, for the first time, the diagnostic reference level of interventional cardiology procedures in Gyeongsang area were established. Using the diagnostic reference level of interventional cardiology procedures derived from this study, it will help to identify and improve the level of exposure dose in the region and country.