• Title/Summary/Keyword: life-stress model

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Rock cutting behavior of worn specially-shaped PDC cutter in crystalline rock

  • Liu, Weiji;Yang, Feilong;Zhu, Xiaohua;Zhang, Yipeng;Gong, Shuchun
    • Geomechanics and Engineering
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    • v.31 no.3
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    • pp.249-263
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    • 2022
  • The specially-shaped Polycrystalline Diamond Compact (PDC) cutter is widely used in drill bit design due to its advantages of high rock cutting efficiency, strong impact resistance and long service life in hard and abrasive formation drilling. A detailed understanding of rock cutting behavior of worn specially-shaped PDC cutter is essential to improve the drilling efficiency and decrease the drilling costs. In this paper, the theoretical models of two new principles (loading performance (LP) and cutting performance (CP)) are derived for evaluating the cutting process of worn specially-shaped cutter, the theoretical models consider the factors, such as cutter geometry, aggressiveness, stress state, working life, and rock cutting efficiency. Besides, the numerical model of heterogeneous granite is developed using finite element method combined with Voronoi tessellation, the LP and CP of 12 kinds of worn specially-shaped PDC (SPDC) cutters are analyzed. The results found that the mechanical specific energy (MSE) of worn cutters first increase and then decrease with increasing the cutting depth, and the MSE increase with the increase of back rake angle except for Conical cutter and Wedge-shaped cutter. From the perspective of CP, the worn PDC cutters are more suitable for the smaller cutting depths, and the back rake angle has little effect on the CP of the specially-shaped worn PDC cutters. Conical cutter, Saddle-shaped cutter and Ellipse-shaped cutter have the highest CP value, while Rhombus-shaped cutter, Convex cutter and Wedge-shaped cutter have the lowest value in selecting cutters. This research leads to an enhanced understanding of rock-breaking mechanisms of worn SPDC cutters, and provides the basis to select of specially-shaped PDC cutters for the specific target formation.

Health Behavior and Health Related Quality of Life of married Males and Females (기혼남성과 여성의 건강행태 및 건강 관련 삶의 질에 관한 연구)

  • Jeong, Yu-Rim;Han, Sam-Sung
    • Journal of muscle and joint health
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    • v.30 no.3
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    • pp.147-156
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    • 2023
  • Purpose: This study examines the health behavior and health-related quality of life (HRQOL) among married men and women, utilizing data from the Korean National Health and Nutritional Examination Survey, encompassing 4,217 subjects. Methods: A multiple regression model was employed to analyze the data. Results: Married men demonstrated a significantly good relationship between HRQOL and perceived health state (β=.32, p<.001), while married women showed a similar relationship with perceived health state (β=.38, p<.001). Additionally, married men demonstrated significantly neutral relationship between HRQOL and perceived health state (β=.30, p<.001), as did the married women (β=.38, p<.001). Both married men (β=-.11, p<.001) and married women (β=-.08, p<.001) were found to experience depression. oreover, the HRQOL in married men was positively associated with private health insurance (β=.08, p=.001), and the same trend was observed in married women (β=.10, p<.001). Married men with unmet medical needs showed a negative association with HRQOL (β=-.08, p<.001), and married women with unmet medical needs showed a similar negative association (β=-.12, p<.001). Furthermore, outpatient medical use(2 weeks) was negatively associated with HRQOL in both married men (β=-.07, p=.001) and married women (β=-.07, p<.001). Moreover, married women displayed a significant negative association between HRQOL and the prevalence of obesity(β=-.04, p=.048) and stress (β=-.05, p=.009) and a positive association with aerobic exercise (β=.04, p=.027). Conclusions: This study suggests that health behavior significantly influences the HRQOL among married men and women. The findings of this study can guide policymakers in developing strategies to improve health behavior and HRQOL within households.

The Trend of Korean Nursing Research with the LISREL (공변량 구조분석을 이용한 국내 간호연구의 동향)

  • 임난영;강현숙;이성은;서연옥;권영은
    • Journal of Korean Academy of Nursing
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    • v.31 no.2
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    • pp.221-231
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    • 2001
  • This study was conducted by analyzing all 33 articles based on the LISREL, published from January 1991 to March 1999 in Korea. The analyses consisted of the publication date of articles, principal dependent variables, subjects of the research, adequacy of sampling, adequacy of research purposes and results, accordance between theoretical model and hypothetical model, fit measures, theoretical base of model modification, and adequacy of conclusion. The results were as follows : . The thesis of 33 articles in total were outnumbered as 25 (75.8%) to 8 (24.2%) research articles. As for a sex classification of the subjects, 45.5% of the research were conducted around a female group of subjects, while 54.5% were done for both sex, The range of the sample size was 105 to 803, and the average was 259 subjects. . A single theoretical variable was measured for each measurement variable, any difference between variables was hardly found in 8 articles (24.2%), and 19 articles (57.6%) did not consider any measurement error. To analyze if the representative has been articles (21.2%) were seen with a sign of a representative. Questionnaires were used in a majority (31 articles) of the data collecting process. Only 2 articles (6.1%) were measured with a physiologic index simultaneously. . 14 articles (42.2%) were centered on theory development, 10 articles on theory synthesis, and 9 articles on theory test. The research purposes and results were consistent in 25 articles (75.5%) and 8 articles (24.2%) were inconsistent. The quality of life and health promotion behavior were the concepts most frequently studied as a dependent variable, and 7 articles centered on them. In applied theories a health promotion model was used on 4 articles (12.1%), while role theory and stress-coping models were in 3 articles respectively. . The articles were analyzed to see if the hypothetical model was elaborated and tested by the theoretical model. Twenty-five articles proved to be rationale for the inconsistencies. Also, 56.5% proposed hypotheses were supported among the subject articles, and 30 articles (90.0%) suggested a revised model. Path coefficient (17 articles) and theoretical adequacy (17 articles) were the standards mostly used. In conclusion, the principal factors were obtained from the research are to be considered as the principes of LISREL application. First, a model has to be established on a theoretical base rather than empirical results dependent on the data. The results are also required to be globally interpreted. Secondly, at least 200 samples are necessary to satisfy the need. Third, more than 3 measurement variables are to be adjusted to a single theoretical variable; the measurement errors must be suggested as well. Finally, normal distribution characteristics of the data and the estimation method need to be reported. Based on the research result, the follows are suggested; . Systematic criteria on the LISREL application and procedure need to be developed . Agreement form is required to report the results of research using the LISREL

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Application of Primary Rat Corneal Epithelial Cells to Evaluate Toxicity of Particulate Matter 2.5 to the Eyes (눈에 대한 미세먼지의 독성 평가를 위한 쥐 각막 상피 세포의 적용)

  • Kim, Da Hye;Hwangbo, Hyun;Lee, Hyesook;Cheong, Jaehun;Choi, Yung Hyun
    • Journal of Life Science
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    • v.32 no.9
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    • pp.712-720
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    • 2022
  • The purpose of this study was to investigate the efficacy of rat corneal-derived epithelial cells as an in vitro model to evaluate the harmfulness of the cornea caused by particulate matter 2.5 (PM2.5). To establish an experimental model for the effect of PM2.5 on corneal epithelial cells, it was confirmed that primary cultured cells isolated from rat eyes were corneal epithelial cells through pan-cytokeratin staining. Our results showed that PM2.5 treatment reduced cell viability of primary rat corneal epithelial (RCE) cells, which was associated with the induction of apoptosis. PM2.5 treatment also increased the generation of reactive oxygen species due to mitochondrial dysfunction. In addition, the production of nitric oxide and inflammatory cytokines was increased in PM2.5-treated RCE cells. Furthermore, through heatmap analysis showing various expression profiling between PM2.5-exposed and unexposed RCE cells, we proposed five genes, including BLNK, IL-1RA, Itga2b, ABCb1a and Ptgs2, as potential targets for clinical treatment of PM-related ocular diseases. These findings indicate that the primary RCE cell line is a useful in vitro model system for the study of PM2.5-mediated pathological mechanisms and that PM2.5-induced oxidative and inflammatory responses are key factors in PM2.5-induced ocular surface disorders.

A Study on the Fatigue Analysis of Glass Fiber Reinforced Plastics with Linear and Nonlinear Multi-Scale Material Modeling (선형과 비선형 다중 스케일 재료 모델링을 활용한 유리섬유 강화 플라스틱의 피로해석 연구)

  • Kim, Young-Man;Kim, Yong-Hwan
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.33 no.2
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    • pp.81-93
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    • 2020
  • The fatigue characteristics of glass fiber reinforced plastic (GFRP) composites were studied under repeated loads using the finite element method (FEM). To realize the material characteristics of GFRP composites, Digimat, a mean-field homogenization tool, was employed. Additionally, the micro-structures and material models of GFRP composites were defined with it to predict the fatigue behavior of composites more realistically. Specifically, the fatigue characteristics of polybutylene terephthalate with short fiber fractions of 30wt% were investigated with respect to fiber orientation, stress ratio, and thickness. The injection analysis was conducted using Moldflow software to obtain the information on fiber orientations. It was mapped over FEM concerned with fatigue specimens. LS-DYNA, a typical finite element commercial software, was used in the coupled analysis of Digimat to calculate the stress amplitude of composites. FEMFAT software consisting of various numerical material models was used to predict the fatigue life. The results of coupled analysis of linear and nonlinear material models of Digimat were analyzed to identify the fatigue characteristics of GFRP composites using FEMFAT. Neuber's rule was applied to the linear material model to analyze the fatigue behavior in LCF regimen. Additionally, to evaluate the morphological and mechanical structure of GFRP composites, the coupled and fatigue analysis were conducted in terms of thickness.

Factors affecting Non-suicidal self-injury: Ecological Momentary Assessment using a Daily Diary Method study (일상생활에서의 비자살적 자해에 영향을 미치는 요인: 생태순간평가 일기법 연구)

  • Hoin Kwon ;Sunjin Kim
    • Korean Journal of Culture and Social Issue
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    • v.29 no.3
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    • pp.321-340
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    • 2023
  • This study was conducted to understand the emotional and situational context where non-suicidal self-injury occurs in everyday life. Sixty adults(age 19-35) completed daily surveys assessing positive and negative emotions, stressful events, self-injury thoughts, and behaviors for two weeks. Using a total of 663 collected entries, we analyzed specific personal emotions and stressful events related to non-suicidal self-injurious thoughts and behaviors. As a result, high negative emotions, low positive emotions, and total stress event scores were significantly related to self-injury thoughts and behaviors. In the model in which both emotion and stress were inserted as predictors, the low level of positive emotion showed a significant related to non-suicidal self-injurious behavior. These results suggest that negative emotion management and overall positive emotion reinforcement are important in emotion regulation intervention for non-suicidal self-injurious patients. The meaning of this study is that it searched for risk factors of non-suicidal injury in everyday life using a short-term longitudinal method.

The Effect of Major Factors in General Health Promotion Behavior Upon Oral Health Promotion Behavior in Some Area Collegian (일부 지역 대학생들의 전신건강증진행위의 주요 요인들이 구강건강증진행위에 미치는 효과)

  • Kim, Jung-Sool;Lee, Byung-Ho
    • Journal of dental hygiene science
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    • v.11 no.6
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    • pp.563-571
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    • 2011
  • The purpose of this study was to identify the major variables against oral health promotion behaviors for collegian in Ulsan area. The measured variables for the oral promotion behaviors presently are previous oral health experience, stress by study, subjective oral health, perceived benefit, perceived barrier, self-esteem, self-efficacy, social support, oral health LOC(locus of control), life satisfaction, emotion and intension based on the Pender's 3th health model as a theoretical model in general health promotion behavior. Total data 330 were analyzed by SPSS 18.0 and AMOS 18.0 program and path analysis method was used to verify the model's fitness. Results for this study were as follows: Firstly, the fitness degrees of research model was ${\chi}^2=39.06$(P>.05), GFI = .982, AGFI = .948, NFI = .967, NNFI = .982, RMSR = .028, so it was apparent that this model was well fitted. Secondly, 27 out of 39 total paths were turned out correspond with the hypothetical model which accepted as direct effect. And two paths had statistical significance in direct. Thirdly, the most positive influences on the oral health promotion behaviors presently were previous oral health experience, subjective oral health, social support, self-efficacy, intension, oral health LOC. And the most negative influences was perceived barrier. So, results from this model we could contribute to identify theirs oral health behavior patterns for collegian in Ulsan.

Proteomic Assessment of the Relevant Factors Affecting Pork Meat Quality Associated with Longissimus dorsi Muscles in Duroc Pigs

  • Cho, Jin Hyoung;Lee, Ra Ham;Jeon, Young-Joo;Park, Seon-Min;Shin, Jae-Cheon;Kim, Seok-Ho;Jeong, Jin Young;Kang, Hyun-sung;Choi, Nag-Jin;Seo, Kang Seok;Cho, Young Sik;Kim, MinSeok S.;Ko, Sungho;Seo, Jae-Min;Lee, Seung-Youp;Shim, Jung-Hyun;Chae, Jung-Il
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.11
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    • pp.1653-1663
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    • 2016
  • Meat quality is a complex trait influenced by many factors, including genetics, nutrition, feeding environment, animal handling, and their interactions. To elucidate relevant factors affecting pork quality associated with oxidative stress and muscle development, we analyzed protein expression in high quality longissimus dorsi muscles (HQLD) and low quality longissimus dorsi muscles (LQLD) from Duroc pigs by liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomic analysis. Between HQLD (n = 20) and LQLD (n = 20) Duroc pigs, 24 differentially expressed proteins were identified by LC-MS/MS. A total of 10 and 14 proteins were highly expressed in HQLD and LQLD, respectively. The 24 proteins have putative functions in the following seven categories: catalytic activity (31%), ATPase activity (19%), oxidoreductase activity (13%), cytoskeletal protein binding (13%), actin binding (12%), calcium ion binding (6%), and structural constituent of muscle (6%). Silver-stained image analysis revealed significant differential expression of lactate dehydrogenase A (LDHA) between HQLD and LQLD Duroc pigs. LDHA was subjected to in vitro study of myogenesis under oxidative stress conditions and LDH activity assay to verification its role in oxidative stress. No significant difference of mRNA expression level of LDHA was found between normal and oxidative stress condition. However, LDH activity was significantly higher under oxidative stress condition than at normal condition using in vitro model of myogenesis. The highly expressed LDHA was positively correlated with LQLD. Moreover, LDHA activity increased by oxidative stress was reduced by antioxidant resveratrol. This paper emphasizes the importance of differential expression patterns of proteins and their interaction for the development of meat quality traits. Our proteome data provides valuable information on important factors which might aid in the regulation of muscle development and the improvement of meat quality in longissimus dorsi muscles of Duroc pigs under oxidative stress conditions.

Regression Analysis of an Excavator Sound Power Level (굴착기의 음향파워레벨 회귀분석)

  • Gu, Jin-Hoi;Lee, Jae-Won;Seo, Chung-Youl;Jang, Seong-Ki;Choi, Kyung-Hee;Han, Jin-Seok
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.22 no.3
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    • pp.203-207
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    • 2012
  • The noise emitted from an excavator has long been a cause of environmental disputes, while causing displeasure to the nearby residents. So, the ministry of environment adopted the construction machinery noise labeling system to encourage the construction machinery manufacturing companies to develop the low noise construction machinery voluntarily. But, as the quality of life improves, a growing number of people desire the comfortable and quite environment to live in. Under the situation, noise from the construction machinery has been a major cause for stress and complaints. When the noise dispute happened in the construction site, the sound pressure level of the construction machinery like a excavator was measured at the lot boundary of the noise victim's residence to judge how much noise damage occur. But the sound pressure level of the construction machinery is measured differently according to the acoustic environment of construction site and the measuring position, respectively, which makes it difficulty to judge whether the noise damage occur or not. As the sound power level of noise source is not affected by the acoustic environment of construction site and the measuring position, if we use the information of the sound power level, it will be easy to judge whether the noise damage occur and to establish the soundproofing measures. Therefore, we derive the sound power level regression model of the excavator to judge whether the noise emitted from the excavator damages to residents near the construction site. Also, the sound power level regression model of the excavator drawn in this paper will help construction companies to plan the noise reduction program in the construction sites.

In silico characterisation, homology modelling and structure-based functional annotation of blunt snout bream (Megalobrama amblycephala) Hsp70 and Hsc70 proteins

  • Tran, Ngoc Tuan;Jakovlic, Ivan;Wang, Wei-Min
    • Journal of Animal Science and Technology
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    • v.57 no.12
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    • pp.44.1-44.9
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    • 2015
  • Background: Heat shock proteins play an important role in protection from stress stimuli and metabolic insults in almost all organisms. Methods: In this study, computational tools were used to deeply analyse the physicochemical characteristics and, using homology modelling, reliably predict the tertiary structure of the blunt snout bream (Ma-) Hsp70 and Hsc70 proteins. Derived three-dimensional models were then used to predict the function of the proteins. Results: Previously published predictions regarding the protein length, molecular weight, theoretical isoelectric point and total number of positive and negative residues were corroborated. Among the new findings are: the extinction coefficient (33725/33350 and 35090/34840 - Ma-Hsp70/ Ma-Hsc70, respectively), instability index (33.68/35.56 - both stable), aliphatic index (83.44/80.23 - both very stable), half-life estimates (both relatively stable), grand average of hydropathicity (-0.431/-0.473 - both hydrophilic) and amino acid composition (alanine-lysine-glycine/glycine-lysine-aspartic acid were the most abundant, no disulphide bonds, the N-terminal of both proteins was methionine). Homology modelling was performed by SWISS-MODEL program and the proposed model was evaluated as highly reliable based on PROCHECK's Ramachandran plot, ERRAT, PROVE, Verify 3D, ProQ and ProSA analyses. Conclusions: The research revealed a high structural similarity to Hsp70 and Hsc70 proteins from several taxonomically distant animal species, corroborating a remarkably high level of evolutionary conservation among the members of this protein family. Functional annotation based on structural similarity provides a reliable additional indirect evidence for a high level of functional conservation of these two genes/proteins in blunt snout bream, but it is not sensitive enough to functionally distinguish the two isoforms.