• Journal of Microbiology and Biotechnology
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• 제33권6호
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• pp.707-714
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• 2023

Plant-derived insecticide-neonicotinoid insecticides (NIs) played a crucial role in the development of agriculture and food industry in recent years. Nevertheless, synthesis of these nitrogen-containing heterocyclic compounds with an effective and greener routing remains challenging especially to the notion raise of "green chemistry" and "atom economy". While bio-catalyzed methods mediated by nicotinate dehydrogenase (NDHase) then provide an alternative. The current review mainly focuses on the introduction of sources, components, structure, catalytic mechanism and applications of NDHase. Specifically, NDHase is known as nicotinic acid hydroxylase and the sources principally derived from phylum Proteobacteria. In addition, NDHase requires the participation of the electron respiratory chain system on the cell membrane. And the most important components of the electron respiratory chain are hydrogen carrier, which is mainly composed of iron-sulfur proteins (Fe-S), flavin dehydrogenase (FAD), molybdenum binding protein and cytochromes. Heterologous expression studies were hampered by the plasmid and host with high efficiency and currently only Pseudomonas entomophila L48 as well as Comamonas testosterone was successfully utilized for the expression of NDHase. Furthermore, it is speculated that the conjugate and inductive effects of the substituent group at position 3 of the substrate pyridine ring exerts a critical role in the hydroxylation reactions at position 6 concerning about the substrate molecular recognition mechanism. Finally, applications of NDHase are addressed in terms of pesticide industry and wastewater treatment. On conclusion, this critical review would not only deepen our understanding of the theory about NDHase, but also provides the guideline for future investigation of NDHase.

• 대한간호학회지
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• 제42권1호
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• pp.28-35
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• 2012

Purpose: This study was done to evaluate the effects of a short-term life review on spiritual well-being, depression, and anxiety in patients with terminal cancer. Methods: The study used a pre posttest quasi experimental design with a nonequivalent control group. Measurement instruments included the Functional Assessment of Chronic Illness Therapy-Spiritual scale (FACIT-Sp12) and the Hospital Anxiety and Depression Scale (HADS). Participants were 32 patients with terminal cancer who were receiving chemotherapy or palliative care at hospitals or at home. Eighteen patients were assigned to the experimental group and 14 to the control group. A sixty minute short-term life review session was held twice a week as the intervention with the experimental group. Results: There was a statistically significant increase in spiritual well-being in the experimental group compared to the control group. There were also significant decreases in depression and anxiety in the experimental group compared to the control group. Conclusion: The results indicate that a short-term life review can be used as a nursing intervention for enhancing the spiritual well-being of patients with terminal cancer.

• 대한원격탐사학회지
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• 제35권6_2호
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• pp.1067-1082
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• 2019

본 논문은 현재 산림 분야 연구에 적용되고 향후 적용가능한 원격탐사 기술에 대한 국내외 발행된 peer-reviewed 논문의 리뷰를 바탕으로 원격탐사 기술의 국내 산림분야 적용에 대한 가능성과 한계점을 서술하였다. 원격탐사 기술은 정밀한 분석과 정교한 자료 수집을 바탕으로 대단위 산림면적 분석에 있어 필수적이며, 정보통신기술과의 융합으로 향후 임업의 새로운 시대를 열어갈 핵심 기술이다. 본 리뷰 논문에서는 다양한 원격탐사 기술 가운데 레이저 스캐닝 기술, 위성영상을 이용한 산림 측정 기술, 그리고 무인항공기를 이용한 기존 국내·외 연구사례를 분석하여 국내 산림분야 적용 가능성에 대한 기회와 한계점에 대해 서술하였다.

• 대한간호학회지
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• 제31권2호
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• pp.279-291
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• 2001

Rapid progress in modern medical technology has made it possible to sustain life and/or delay death using 'heroic' treatments. The availability of life-sustaining treatment brings several issues in end-of-life care such as 'dying with dignity' and an radical increase in health care costs. The use of Advance Directives(AD) have been widely heralded by health care providers, gerontologists, and advocacy groups as means of protecting patients' right to accept or refuse life-sustaining treatment in end-of-life care. The use of AD can not only improve patients' autonomy and quality of life but also bring efficiency in distributing health care resources. The proportion of older persons in Korean population has been increasing. Those 65 years of age or over were about 7 percent of the population. Death and dying is not limited to older persons, but it is more prevalent among them. In conjunction with an aging population and the increasing prevalence of death, the issues of death and dying will become crucial in near future in terms of 'dying with dignity', 'autonomy', and 'self-control'. This paper attempts to explode and establish the concept of advance directives (AD) based on literature review. Data sources are computer searches with the MEDLINE database. Due to the lack of prior study on AD for a Korean cases, studies abroad are reviewed. This paper suggests the need for future study on the possibility of the use of AD in Korea.

• Reproductive and Developmental Biology
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• 제37권2호
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• pp.85-89
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• 2013

For more than two decades, the intracytoplasmic sperm injection (ICSI) technique has been used as a valuable tool to provide opportunities for studying fertilization, treating human infertility, and producing transgenic animals. Not only in facilitating fertilization but also in propagating mammalian species, ICSI has enhanced the potential of assisted reproductive technologies in human. Polyspermic fertilization has been one of major problems in pig reproduction, but the ICSI helped to solve the problem, and used widely to generate transgenic piglets. Although the ICSI technique is considered to be a very useful tool in assisted reproductive technologies, including generation of transgenic animals, there are some disadvantages using the technique. In this review, we describe the ICSI technique and its application in animal production and human infertility, and discuss advantage and disadvantage of the technique in mammals.

• 한국해양바이오학회지
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• 제5권4호
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• pp.1-7
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• 2011

Bone health is maintained by balance between bone resorption and bone formation, and bone homeostasis requires balanced interactions between osteoblasts and osteoclasts. Most of drugs and functional foods for bone health have been developed as bone resorption inhibitors, which maintain bone mass by inhibiting the function of osteoclasts. The recent studies have shown beneficial effects of marine natural products on bone health. Therefore, this review is aimed to study effects of marine-derived natural substances on osteoarthritis inhibition via attenuation of MMPs and osteoblastic differentiation via activation of alkaline phosphatase (ALP), osteoclacin (OC), bone morphogenic protein-2 (BMP-2) as an important factor for bone formation, and mineralization. The present review can provide new insights in the osteoblastic differentiation of marine natural products and possibility for their application in bone health supplement.

• International journal of advanced smart convergence
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• 제9권4호
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• pp.124-131
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• 2020

As users of internet-based software applications increase, functional and non-functional problems for software applications are quickly exposed to user reviews. These user reviews are an important source of information for software improvement. User review mining has become an important topic of intelligent software engineering. This study proposes a user review mining method for software improvement. User review data collected by crawling on the app review page is analyzed to check user satisfaction. It analyzes the sentiment of positive and negative that users feel with a machine learning method. And it analyzes user requirement issues through topic analysis based on structural topic modeling. The user review mining process proposed in this study conducted a case study with the a non-face-to-face video conferencing app. Software improvement through user review mining contributes to the user lock-in effect and extending the life cycle of the software. The results of this study will contribute to providing insight on improvement not only for developers, but also for service operators and marketing.

• 보험의학회지
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• 제29권1호
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• pp.4-6
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• 2010

The life expectancy of HIV-infected subjects has improved dramatically since the introduction of highly-active antiretroviral therapy (HAART). Considering that patients with HIV infection are living longer, treatment plans should include those for the accompanying co-morbidities such as cardiovascular diseases, metabolic syndrome, malignancy, etc. This review discusses the impact of HAART on the epidemiology of survival and co-morbidities (malignancy and cardiovascular diseases) among HIV-infected subjects.

• 가정과삶의질연구
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• 제18권3호통권47호
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• pp.147-170
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• 2000

The purpose of this study is to review Korean sacrificial rite and reform it to be fit for modern life, the research method is to review literatures such as ancient writings and various references for the sacrificial rite. The new model of Korean sacrificial rite is as follows; 1. New year's and chusok's sacrificial rite should be omitted and only the anniversary rite be left. 2. Time of anniversary rite should be convenient hour that all attendants can meet and the extent of attendants should be limited into the deads sons & daughters. 3. Subject of anniversary rite should be limited into the parents. 4. Foods and liquor offered to the dead should be omitted 5. Supervisor of sacrificial rite should be not only the eldest son but also dead's sons and daughters, so the anniversary rite should be rotated among brothers and sisters.

• 보험의학회지
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• 제26권
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• pp.41-53
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• 2007

In the course of insurance claim administration, medical experts' opinions are called medical claim reviews. They are classified into two main categories: medical verification and counsel for claim staff. Medical verification compare between product coverage and the insured's physical condition. Medical counsel for claim staff is advice for claim staff when they have a question about medical knowledge to make a claim decision. A common example of medical verification is insurance coding of pituitary apoplexy. Some clinicians have insisted that the ICD coding of pituitary apoplexy is l63 of cerebral infarction, but the exclusion criteria of I code show that neoplasm is coded as C00 to D48. Thus, pituitary apoplexy must be coded as D33. An example of medical counsel for claim staff is interpretation of some medical conditions. It is divided into UCR(usual, customary, and reasonable) assessment, assessment of causality, and so on. Disability evaluation is another subject of medical counsel for claim staff. The final claim decision must be made by claim staff because only the claim staff have the authority of claim decision. Medical claims review is only an expert's opinion.