• Title/Summary/Keyword: lgG

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Changes of serum immunoglobulin in the subacute oral administration of bisphenol A

  • Byun, Jung-A;Pyo, Myoung-Yun
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.296.1-296.1
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    • 2002
  • Bisphenol A(BPA). a monomer used in the manufacturing epoxy resins and polycarbonates. has been reported to induce estrogenic activity, it has been considered as an environmental endocrine disruptor. But the immunomodulatory effects of BPA exposure have not been systemically evaluated. We investigated whether BPA effects on the ability of immunoglobulin(lg) production of mice. To initiate investigation of BPA-induced alterations of the immune system. BPA at dose of 100. 500,1000 mg/kg b.w./day with or without OVA-antigen for 30 days were orally administered to female ICR mice. Mice were sacrificed and serum was colleted on day 2 following administration of BPA for 30days. Total lgG1. total lgG2a. total lgE. OVA-specific lgG1. OVA-specific lgG2a. and OVA-specific lgE in serum were detetmined and compared with those of non-treated mice. In the groups of BPA with OVA antigen, total 1gG1, total lgG2a, total lgE. OVA-specific lgG1 and OVA-specific lgG2a were significantly decreased at dose of 500mg/kg/day. However, in mice treated with BPA alone, total lgG1, and lgG2 were not much altered and total lgE was significantly increased at dose of 1000mg/kg/day. These results demonstrated the BPA modulates the production of immunoglobulin.

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Validation of Cloud Robotics System in 5G MEC for Remote Execution of Robot Engines (5G MEC 기반 로봇 엔진 원격 구동을 위한 클라우드 로보틱스 시스템 구성 및 실증)

  • Gu, Sewan;Kang, Sungkyu;Jeong, Wonhong;Moon, Hyungil;Yang, Hyunseok;Kim, Youngjae
    • The Journal of Korea Robotics Society
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    • v.17 no.2
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    • pp.118-123
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    • 2022
  • We implemented a real-time cloud robotics application by offloading robot navigation engine over to 5G Mobile Edge Computing (MEC) sever. We also ran a fleet management system (FMS) in the server and controlled the movements of multiple robots at the same time. The mobile robots under the test were connected to the server through 5G SA network. Public 5G network, which is already commercialized, has been temporarily modified to support this validation by the network operator. Robot engines are containerized based on micro-service architecture and have been deployed using Kubernetes - a container orchestration tool. We successfully demonstrated that mobile robots are able to avoid obstacles in real-time when the engines are remotely running in 5G MEC server. Test results are compared with 5G Public Cloud and 4G (LTE) Public Cloud as well.

Production of 3-Hydroxypropionic Acid from Acrylic Acid by Newly Isolated Rhodococcus erythropolis LG12

  • Lee, Sang-Hyun;Park, Si-Jae;Park, Oh-Jin;Cho, Jun-Hyeong;Rhee, Joo-Won
    • Journal of Microbiology and Biotechnology
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    • v.19 no.5
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    • pp.474-481
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    • 2009
  • A novel microorganism, designated as LG12, was isolated from soil based on its ability to use acrylic acid as the sole carbon source. An electron microscopic analysis of its morphological characteristics and phylogenetic classification by 16S rRNA homology showed that the LG12 strain belongs to Rhodococcus erythropolis. R. erythropolis LG12 was able to metabolize a high concentration of acrylic acid (up to 40 g/l). In addition, R. erythropolis LG12 exhibited the highest acrylic acid-degrading activity among the tested microorganisms, including R. rhodochrous, R. equi, R. rubber, Candida rugosa, and Bacillus cereus. The effect of the culture conditions of R. erythropo/is LG12 on the production of 3-hydroxypropionic acid (3HP) from acrylic acid was also examined. To enhance the production of 3HP, acrylic acid-assimilating activity was induced by adding 1 mM acrylic acid to the culture medium when the cell density reached an $OD_{600}$ of 5. Further cultivation of R. erythropo/is LG 12 with 40 g/l of acrylic acid resulted in the production of 17.5 g/l of 3HP with a molar conversion yield of 44% and productivity of 0.22 g/l/h at $30^{\circ}C$ after 72 h.

LG U+의 5G 이동통신 콘텐츠 서비스 제공 전략 (사례)

  • Baek, Yong-Dae
    • Broadcasting and Media Magazine
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    • v.24 no.3
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    • pp.89-99
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    • 2019
  • LG 유플러스는 5G 서비스를 세계 최초로 상용화함에 따라 5G의 기술적 특징인 초고속, 대용량, 초저지연, 초연결의 특성으로 앞으로 실감 미디어 시대가 대두될 것에 대비, 5G 서비스 이용자들의 일상을 바꾸는 콘텐츠 서비스를 제공 중이다. 특히 이용자들이 직접 체험을 통해 5G 콘텐츠가 개개인의 일상과 밀접한 연관이 있다는 부분을 강조하여 서비스를 제공하고자 최선의 노력을 다하고 있다. 본 고에서는 이처럼 5G 서비스 이용자들이 선호하는 콘텐츠 이용을 '일상로 5G길' 팝업 스토어 운영 사례를 통해 소개하고, LG U+ 주요 서비스, 5G 콘텐츠 확산 방안, 기대 효과, 마지막으로 결론 및 주요 시사점에 대해 서술하였다.

The penetration enhancement and the lipolystic effects of TAT-GKH, in both In vitro, Ex vivo, and In vivo.

  • Lim, J.M.;Chang, M.Y.;Park, S.G.;Kang, N.G.;Song, Y.S.;Lee, Y.H.;Yoo, Y.C.;Cho, W.G.;Han, S.G.;Kang, S.H.
    • Proceedings of the SCSK Conference
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    • 2003.09b
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    • pp.87-107
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    • 2003
  • It was demonstrated that Transactivating transcriptional activator(TAT) protein from HIV-1 shown to enter cells when added to the surrounding media. TAT peptide chemically attached to various proteins was able to deliver these proteins to various cell and even in tissues in mice with high levels in heart and spleen. In this study, the tripeptide GKH(Glycine-Lysine-Histidine) derived from Parathyroid hormone (PTH), which was known as lipolytic peptide, is attached to 9-poly Lysine(TAT) to be used as a cosmetic ingredient for slimming products. When Glycerol release, expressed as extracellular glycerol concentration, is lipolysis index, TAT-GKH at $10^{-5}$mo1/L induces approximately 41.5% maximal lipolytic effects in epididymal adipocytes isolated from rats, compared with basal lipolysis. Epididymal adipose tissues of male rats is assessed ex vivo by microdialysis. Probes are perfused with Ringer solution in which increasing concentrations of TAT-GKH. The perfusion of TAT-GKH induces lipolytic effect. Penetration study showed that TAT-GKH efficiently elevates 36 times higher penetration into the excised hairless mice skin than GKH. in vivo study showed that TAT-GKH had a better effect upon the relative volume of eye bag after 28 days of application on twenty(+2) healthy female volunteers. It was identified that TAT-GKH increases penetration enhancement and lipolytic effects in both in vitro, ex vivo and in vivo.

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Studies on Antioxidant, Anti-inflammation and Moisturizing Activities of Gastrodia elata Flower Extract (천마꽃 추출물의 항산화, 항염, 보습 활성에 대한 연구)

  • Lee, Hong Gu;Kim, Gil Nam;Park, Dong Jun;Lee, So Young;Jin, Mu Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.3
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    • pp.219-226
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    • 2021
  • Gastrodia elata has a very low pollination rate in natural state, and even in artificial cultivation, there are very few individuals that bloom due to the degeneration, so little studies have been conducted. This study confirmed that the potential as a cosmetic ingredient by evaluating the antioxidant activity through the evaluation of DPPH radical scavenging activity, anti-inflammatory activity through the inhibitory effect on nitric oxide production, and the moisturizing activity through the effect on promoting hyaluronic acid production by artificially flowering G. elata flower. It was also confirmed that the appearance rate and flowering rate of G. elata harvested in spring were high, and the content of gastrodin was 0.36%. The IC50 value of G. elata flower extract was 0.045% and it was confirmed that G. elata flower extract had higher radical scavenging activity than G. elata root extract. The NO production inhibitory activity against the flower extract showed a significant inhibitory effect from 1% to 83.2%. Hyaluronic acid production promotion efficacy was not confirmed in the G. elata root extract, but the production rate increased with concentration dependence in the flower extract, and it was the highest at 46.9% when 0.02% treatment was performed. Based on the above research results, it is judged that G. elata flower extract has high potential for use as an antioxidant, anti-inflammatory, and skin moisturizing cosmetic ingredient.

Nutrient Absorption and Endosperm Consumption in Rice Seedling (벼 육모일수에 따른 양분흡수와 배유양분 소모)

  • Kim, Sang Su;Choi, Min Gue;Lee, Seon Yong;Cho, Soo Yeon;Jun, Byung Tae
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.41 no.4
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    • pp.405-410
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    • 1996
  • To elucidate the pattern of nutrient absorption and endosperm consumption as the seedling age of rice, Dongjinbyeo was raised in the seedling box with different nitrogen levels. Absorption of nitrogen and phosphorus were high in the order of artificial seed bed soil, sand with N-1g /box and sand without N from 3 and 5 days after seeding but, potassium wasn't significantly different between sand+N-1g /box and sand. Endosperm consumption rate was high in the order of artificial seed bed soil, sand + N-1g /box and sand but, endosperm dependence rate (endosperm consumption /top dry weight) was vice versa. Seedling height and dry weight were higher in the order of artificial seed bed soil, sand+N-1g /box and sand from 3 days after seeding, number of leaves were more from 5 days after seeding in same order.

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A study of ALP for elevator (엘리베이터용 정전시 비상구출장치에 관한 연구)

  • Jang, C.H.;Lee, G.H.;Hur, H.J.;Lee, J.G.;Kim, H.J.;Choi, C.S.;Jeong, J.T.
    • Proceedings of the KIEE Conference
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    • 1997.07f
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    • pp.2013-2015
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    • 1997
  • Elevator stops emergently when power failures happen during operation. In that case, the passenger should wait with frightened in the car untill they are rescued by repair man or power resumes. This paper describes an automatic landing device for power-failure(ALP) that consists of UPS and battery charge control system. The excellence of the ALP operation is verified by experiments in elevator test tower.

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