• 아동학회지
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• 제35권4호
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• pp.179-198
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• 2014

The main purpose of this study was to examine direct and indirect effects of mothers' depression on preschoolers' externalizing problem behaviors. A total of 155 mothers with preschoolers aged 3 and 4 years (83 boys and 72 girls) living in Seoul participated in this study. Mothers completed questionnaires on mothers' depression, parenting behavior, and preschoolers' externalizing problem behaviors. Direct and indirect pathways from mothers' depression to preschoolers' externalizing problem behaviors were analyzed using Structural Equation Modeling (SEM). First, it was revealed that mothers' depression did not directly affect preschoolers' externalizing problem behaviors. Second, mothers' depression indirectly influenced preschoolers' externalizing problem behaviors through mothers' parenting behavior. Mothers who reported higher levels of depression showed less warmth/acceptance and more rejection/restriction towards their children, which led to higher levels of preschoolers' externalizing problem behaviors. These findings emphasize the importance of positive parenting by mothers in reducing preschoolers' problem behaviors.

• International Journal of Industrial Entomology and Biomaterials
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• 제43권2호
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• pp.45-51
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• 2021

High blood cholesterol levels and oxidized cholesterol are risk factors for cardiovascular disease, which displays high annual incidence. Although studies on sericulture products, including pupae, silk protein, and blood lymph, as hypocholesterolemic substances have been reported, insufficient research in this field has been focused on silkworm larvae. Six larval extracts (Low temperature distilled water, LW; hot temperature distilled water, HW; and 30-100% ethanol, E30-E100) were prepared, and their effects on cholesterol metabolism were examined. LW most potently reduced the risk of cholesterol-related disorders. Polyphenols were highly represented in LW, corresponding with its increased antioxidant potency. The cholesterol biosynthesis enzyme, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) was strongly inhibited by LW. Hepatocytes over-expressed LDL receptor (LDLR) after LW stimulation, promoting cholesterol elimination from plasma. LW also increased ATP binding cassette transporter 1 (ABCA1) gene expression, upregulating HDL biogenesis. In conclusion, LW exhibited strong antioxidant activity, suppressed cholesterol biosynthesis, improved LDL uptake from plasma, and upregulated HDL biosynthesis. In aggregate, these activities could reduce blood cholesterol levels and prevent cardiovascular disease.

• 한국항해항만학회지
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• 제29권8호
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• pp.701-707
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• 2005

본 연구의 목적은 항만전문가들의 의견을 통해서 우리나라의 항만개발 우선순위를 선정하는데 있다. 이를 위해 선행 연구들과 항만관련 전문가들로부터 브레인스토밍(brainstorming)을 수행하여 87개의 세부속성을 도출하였다. 그리고 KJ기법을 통해 6개의 평가기준으로 그룹핑하여 계층분석구조를 구축하고, AHP 기법을 통해 각 계층의 상대적 중요도, 항만 전문가들의 선호 경향 및 대안들의 종합 중요도를 평가하였다. 이 연구를 통해 우리나라의 항만개발 우선순위를 선정하고 이어 따른 우리나라 항만개발에 대한 발전 방향을 제시하고자 한다.

• 농약과학회지
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• 제16권3호
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• pp.236-241
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• 2012

시설재배 풋고추 및 착색단고추의 재배과정 중 살포되는 chlorpyrifos의 잔류특성을 밝히고자 재배시기 및 약제살포 방법별 잔류량을 조사, 평가하였다. 고추의 재배시기별 열매 중 chlorpyrifos 잔류는 하절기(6~7월)에 비해 동절기(2~3월)에 1.5~2.7배 높게 검출되었다. 동절기 재배중인 풋고추와 착색단고추에 7일 간격 3회 약제 살포 후 1~10일 동안의 잔류량을 비교하였다. 고추 중 잔류량은 1일차 2.070에서 10일차 $0.929mg\;kg^{-1}$로 감소하였으며, 착색 단고추는 1일차 0.302에서 10일차 $0.291mg\;kg^{-1}$으로 감소하여 두 농산물간의 농약잔류량은 6.9~3.2배 차이를 보였다. 착색단고추에 약제를 3일과 7일 간격으로 3회 살포 후 1~10일 동안의 농약잔류량은 각각 0.498~0.291, $0.302{\sim}0.267mg\;kg^{-1}$ 범위였다. 착색단고추에 살포농도를 표준량과 배량으로 처리하였을 때 열매 중 농약의 잔류농도는 배량 처리시 2.5배 정도 높았으며, 살포 물량을 달리 했을 때의 영향은 거의 없었다.

• 한국환경과학회지
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• 제14권4호
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• pp.413-425
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• 2005

The 16 priority PAHs (Polycyclic Aromatic Hydrocarbons) designated by US Environmental Protection Agency were analyzed for some digested sludges from wastewater treatment plants in Korea. PAHs are an important group of organic contaminants present in sewage sludge due to their persistence and toxic potential. PAHs were extracted from freeze-dried sludges using a methylene chloride-methanol (2:1) mixture in a soxhlet extractor. The extracts were cleaned-up by silica gel/alumina combination column and subsequently fed into gas chromatograph/mass spectrometer (GC/MS) for determining PAH contents. The sum of the 16 PAHs in the sewage sludge varied from 534.8 to $5754.5 {\cal}ug/{\cal}kg$, dry wt.. In the sewage sludge, phenanthrene appears as the most abundant PAHs, followed by naphthalene, pyrene, fluoranthene. Source of the investigated sewage sludges relatively predominated pyrogenic. PAHs levels of sewage sludges in Korea appeared to be lower than those in other countries.

• Molecules and Cells
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• 제41권6호
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• pp.603-611
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• 2018

Triglyceride homeostasis is a key process of normal development and is essential for the maintenance of energy metabolism. Dysregulation of this process leads to metabolic disorders such as obesity and hyperlipidemia. Here, we report a novel function of the Drosophila flightless-I (fliI) gene in lipid metabolism. Drosophila fliI mutants were resistant to starvation and showed increased levels of triglycerides in the fat body and intestine, whereas fliI overexpression decreased triglyceride levels. These flies suffered from metabolic stress indicated by increased levels of trehalose in hemolymph and enhanced phosphorylation of eukaryotic initiation factor 2 alpha ($eIF2{\alpha}$). Moreover, upregulation of triglycerides via a knockdown of fliI was reversed by a knockdown of desat1 in the fat body of flies. These results indicate that fliI suppresses the expression of desat1, thereby inhibiting the development of obesity; fliI may, thus, serve as a novel therapeutic target in obesity and metabolic diseases.

• Journal of Animal Science and Technology
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• 제55권6호
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• pp.521-530
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• 2013

Direct cell-cell communication via the transfer of small molecules between neighboring cells in tissue is accomplished by gap junctions composed of various connexins (Cxs). Proper postnatal development of the epididymis is important for acquisition of male reproduction. The epididymal epithelium is composed of several cell types, and some of these cells are connected by gap junctions. The present study was conducted to determine the presence of Cx transcripts in the corpus and cauda epididymis. In addition, transcriptional changes of Cxs expressed during different postnatal stages were examined by real-time PCR analysis. In both epididymal regions, the same nine Cx transcripts of thirteen Cxs tested were detected. In the corpus epididymis, the highest levels of Cxs31.1 and 37 transcripts were observed at 45 days of age, and amounts of Cxs26, 30.3, and 32 transcripts increased with age and subsequently decreased in the elderly. Expression of Cx31 was greatly increased in the adult and elder stages, while Cxs40, 43, and 45 were abundant in the early postnatal stages. In the cauda epididymis, expression of Cxs26, 30.3, 31.1, 37, and 40 reached the highest levels at 5 months of age. The levels of Cxs31 and 32 mRNAs fluctuated throughout the postnatal period. The amounts of Cxs43 and 45 transcripts were more abundant during the late neonatal and prepubertal ages than later ages. These findings suggest that regional specification of the epididymis is partly regulated by differential expression of Cx genes during the postnatal developmental period.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2007년도 추계 학술논문 발표대회
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• pp.67-70
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• 2007

In this study, the characteristic of strength development of high volume fly ash concrete(HVFAC) was experimentally investigated. The production of one ton of portland cement releases about 0.87ton of CO2 into the atmosphere. HVFAC is an emerging material technology and is environmentally friendly because of its reduced use of portland cement, reduced CO2 emissions. For this purpose, two levels of W/B were selected. Seven levels of fly ash replacement ratios and two levels of silica fume replacement ratios were adopted. In the concrete mix, the water content of 125kg/m3 was used, which is less than that of usual water content. As a result, it was observed that the slump of concrete was increased with the increasing fly ash replacement ratio and when the silica fume was incorporated into the concrete, the slump was significantly decreased at the same condition. It appeared that the compressive strength gradually decreased with increasing fly ash replacement ratio at the early age, but the difference of strength up to replacement ratio of 50% was little at the age of 91 days because of the pozzolanic reaction of fly ash.

• 아동학회지
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• 제32권4호
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• pp.83-97
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• 2011

The purpose of this study was to examine the relationship between socioeconomic status, maternal involvement in learning, parenting behavior and children's self-determination motivation. The participants of this study consisted of 333 fifth- and sixth-grade elementary school children and their mothers living in Seoul. The results of this study indicated that mothers with a higher educational attainment reported greater autonomy support behavior and involvement in their offspring's learning. Conversely, mothers with low incomes were found to use psychological control and were also found to be involved in learning to a lesser degree. Hierarchical multiple regression analysis indicated that children whose mothers were less involved in learning showed higher levels of self-determination motivation. Additionally, maternal support for autonomy and psychological control had a number of moderating effects on the association between maternal involvement in learning and the child's self-determination motivation. Specifically, children tended to exhibit significantly lower levels of self-determination motivation when mothers were more involved in learning among those who received less support in terms of autonomy. Conversely, children had significantly higher levels of self-determination motivation when mothers were less involved in learning when it came to those children who were under less psychological control.

• Food Science and Biotechnology
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• 제14권6호
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• pp.841-846
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• 2005

Using high-fat-fed C57BL/6 mice, therapeutic effects of oral administration of aqueous extracts of Platycodon grandiflorum and Acanthopanax senticosus on obesity were evaluated by comparing body and liver weights, feed intake, adipose tissue mass, blood lipid profile, and triglyceride and total cholesterol levels in liver and feces. Obesity was successfully induced in high-fat diet group. P. grandiflorum and A. senticosus were effective in reducing food intake, serum lipid levels, adipose tissue accumulation, and weight. P. grandiflorum extract reduced triglyceride and cholesterol levels in liver by excluding them in feces. A. senticosus extract increased triglyceride level in liver but decreased in feces, and decreased total cholesterol in liver and feces, indicating active ingredient of A. senticosus exert antiobesity effect through mechanism different from that of P. grandiflorum extract. These results suggest aqueous extracts of P. grandiflorum and A. senticosus have synergistic effect for prevention of hyperglyceridemia and obesity.