• Journal of architectural history
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• v.2 no.1 s.3
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• pp.54-73
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• 1993

This study focuses on the staffs of the Governmental Organization of Construction who actually led this organization. Two main points of this study are as follows; 1) The composition and appointment of staffs, before and after the Korea-Japan Treaty in 1907, are evaluated, and 2) The working and academic career of each personnel are analyzed in connection with understanding of internal characteristics of this organization. Special attention is given to Korean personel and Japanese engineers who undertook a leading role. Korean engineering staffs were very few in number. It is thought, viewing their records of careers, that almost all of them didn't have any engineering basis, and simply they had some relations to Japan. It is certain that their role in this organization was interpreters using their Japanese language ability, and their roles were only limited to non-technical areas, if any. The early engineers from Japan were selected among the officials with comparatively rich careers of the Temporary Architectural Dept. or the Temporary Engineering Dept. of Custom House in Japan. But, in later days, the quality of Japanese engineers changed to the level of premature without practical experiences who unwillingly came to Korea to have a job under the depression of construction economy of Japan. The academic careers of Japanese engineers were various, from self-taught to regural college education, but the leading engineers were from Tokyo University. The civil engineers became high-level technical officials in the Government-General after the Japanese Annexation of Korea. But, sometimes later, many of the architectural engineers became practicing architect managing design offices on private basis.

• Journal of Korea Port Economic Association
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• v.35 no.3
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• pp.109-124
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• 2019

Corporate social responsibility (CSR) is gaining significance in various industries and academic research. However, shipping companies have a relatively less interest in CSR. Considering the International Maritime Organisation's (IMO) 2020 model and its focus on sustainability, it is time for shipping companies to consider the active use of CSR initiatives. This study aims to examine the leading factors influencing CSR implementation and job satisfaction. The analysis was conducted using partial least squares and statistical package for social sciences 18.0 to achieve the research objectives. The results showed that the internal and external factors of shipping companies play a positive role in CSR implementation, which was found to play a positive role in enhancing job satisfaction. The implications of this study are to identify factors that drive shipping companies to improve their CSR performance.

• Journal of Information Management
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• v.37 no.4
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• pp.105-124
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• 2006

The nuclear knowledge management is now being operated in the KAERI and also actively practiced in other member states of the IAEA. The INIS secretariat leads the knowledge management. As the traditional service areas of librarians are decreasing, the knowledge management is considered as a promising service area replacing the traditional librarian's role. This new area is in Blue Ocean and needs to great concern and understanding. INIS is the world's leading information system on the peaceful uses of nuclear energy. INIS is operated by the IAEA in collaboration with its member states and cooperating international organizations. INIS has more than 2.7 million items and provides users a comprehensive information reference service for literature in nuclear science and technology. The input amount ranks fifth in the world and it operates the INIS 2 host site. INIS in Korea is playing a leading role in the IAEA.

• BMB Reports
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• v.56 no.9
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• pp.482-487
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• 2023

Hematopoiesis is regulated by crosstalk between long-term repopulating hematopoietic stem cells (LT-HSCs) and supporting niche cells in the bone marrow (BM). Here, we describe the role of KAI1, which is mainly expressed on LT-HSCs and rarely on other hematopoietic stem-progenitor cells (HSPCs), in niche-mediated LT-HSC maintenance. KAI1 activates TGF-β1/Smad3 signal in LT-HSCs, leading to the induction of CDK inhibitors and inhibition of the cell cycle. The KAI1-binding partner DARC is expressed on macrophages and stabilizes KAI1 on LT-HSCs, promoting their quiescence. Conversely, when DARC+ BM macrophages were absent, the level of surface KAI1 on LT-HSCs decreases, leading to cell-cycle entry, proliferation, and differentiation. Thus, KAI1 acts as a functional surface marker of LT-HSCs that regulates dormancy through interaction with DARC-expressing macrophages in the BM stem cell niche. Recently, we showed very special and rare macrophages expressing α-SMA+ COX2+ & DARC+ induce not only dormancy of LT-HSC through interaction of KAI1-DARC but also protect HSCs by down-regulating ROS through COX2 signaling. In the near future, the strategy to combine KAI1-positive LT-HSCs and α-SMA/Cox2/DARC triple-positive macrophages will improve the efficacy of stem cell transplantation after the ablative chemo-therapy for hematological disorders including leukemia.

• Annals of Clinical Neurophysiology
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• v.10 no.2
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• pp.98-100
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• 2008

Restless legs syndrome (RLS) is a sensorimotor neurological disorder in which the primary symptom is a compelling urge to move the legs, accompanied by unpleasant and disturbing sensations in the legs. Although pathophysiologic mechanism of RLS is still unclear, several evidences suggest that RLS is related to dysfunction in central nervous system involving brain and spinal cord. L-DOPA, as the precursor of dopamine, as well as dopamine agonists, plays an essential role in the treatment of RLS leading to the assumption of a key role of dopamine function in the pathophysiology of RLS. Patients with RLS have lower levels of dopamine in the substantia nigra and respond to iron administration. Iron, as a cofactor in dopamine production, plays a central role in the etiology of RLS. Functional neuroimaging studies using PET and SPECT support a central striatal D2 receptor abnormality in the pathophysiology of RLS. Functional MRI suggested a central generator of periodic limb movements during sleep (PLMs) in RLS. However, to date, we have no direct evidence of pathogenic mechanisms of RLS.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.125.2-125.2
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• 2016

Semiconductor nanowires are essential building blocks for various nanotechnologies including energy conversion, optoelectronics, and thermoelectric devices. Bottom-up synthetic approach utilizing metal catalyst and vapor phase precursor molecules (i.e., vapor - liquid - solid (VLS) method) is widely employed to grow semiconductor nanowires. Al has received attention as growth catalyst since it is free from contamination issue of Si nanowire leading to the deterioration of electrical properties. Al-catalyzed Si nanowire growth, however, unlike Au-Si system, has relatively narrow window for stable growth, showing highly tapered sidewall structure at high temperature condition. Although surface chemistry is generally known for its role on the crystal growth, it is still unclear how surface adsorbates such as hydrogen atoms and the nanowire sidewall morphology interrelate in VLS growth. Here, we use real-time in situ infrared spectroscopy to confirm the presence of surface hydrogen atoms chemisorbed on Si nanowire sidewalls grown from Al catalyst and demonstrate they are necessary to prevent unwanted tapering of nanowire. We analyze the surface coverage of hydrogen atoms quantitatively via comparison of Si-H vibration modes measured during growth with those obtained from postgrowth measurement. Our findings suggest that the surface adsorbed hydrogen plays a critical role in preventing nanowire sidewall tapering and provide new insights for the role of surface chemistry in VLS growth.

• Proceedings of the Society of Korea Industrial and System Engineering Conference
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• 2002.05a
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• pp.217-226
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• 2002

Under the sudden change of competitive environment, the economic cooperation as a part of survival strategy is being a big issue among countries. There was much discussion based on the geological adjacency as well as cultural homogeneity regarding the economic cooperation of three countries, Korea, China, Japan. It has been also known that major trade countries of the world concluded the treaty of region trade, then extended the number of export, and drew a success in foreign direct investment. Resent automobile industry is being ran by the center of America, Europe and Japan. Korea only has a successful experience of restoration of automobile industry in the half of a century after his beginning. It is true that China is trying to do best to raise his automobile industry. Also Japan is a leading automobile country guiding automobile industry all over the world. It can be considered that Korea will play a major role in the three countries' automobile industry based on Japanese demonstrated technology, Chinese resources, market and experience with their economic cooperation. Therefore it is expected that a big result will be achieved throughout such a role play of each country. This paper has a purpose to light up the distinctive quality and the present condition of each country in automobile Industry, and to promote the foundation of three countries' economic cooperation. It is convinced that the economic cooperation of three countries, Korea, China and Japan in automobile industry, will play a great role in the world automobile market.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.5-7
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• 2003

NADPH is an essential co-factor for fat and cholesterol biosynthesis. However, the role of cytosolic NADP$\^$＋/-dependent isocitrate dehydrogenase (IDPc), a putative NADPH producer, in the control of the fat and cholesterol metabolism has not been assessed. Here we report that increased or decreased IDPc expression in 3T3-Ll fat cells promoted or retarded adipogenesis, respectively. Furthermore, overexpression of IDPc in transgenic mice exhibited fatty liver, hypertriglyceridemia, hypercholesterolemia and obesity by increasing NADPH production leading to subsequent stimulation of acetyl-coenzyme A and malonyl-coenzyme A consumption. In contrast, administrations of a synthetic IDPc inhibitor, DAl1004, to ob/ob mice effectively reduced body weight with lowering cholesterol and triglyceride levels. In addition, a positive relationship (${\gamma}$ = 0.69, $\rho$<0.0l) between plasma IDPc activity and body mass indexes was observed in 98 randomly-selected human volunteers. Our findings strongly indicate that NADPH produced by IDPc plays an important role in controlling body fat and lipid biosynthesis.

• Hwankyungkyoyuk
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• v.19 no.2 s.30
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• pp.159-171
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• 2006

A benefit-oriented socio-economic system causes environmental problems that become obvious and more serious on the earth. Therefore, every country in the world is making various efforts to solve serious environmental issues for making the sustainable society. And it is thought that environmental education should play a key role to make the efforts fruitful. Especially, enterprises should be given an important role on environmental education in the future society. This study inquires present activities done by enterprises on environmental education analyze their achievement and aims to clarify the role and prospects on environmental education in the future that the enterprise should carry out. The major results of this research are as follows; First, The approach form of the enterprise concerning environmental education can be classified into four stages, namely 'beginning stage', 'evolution stage', 'development stage' and 'partnership stage'. Present activities on environmental education have not been reached there though 'partnership stage' will be necessary for the sustainable society. Second, In the execution of environmental education, it independently works on environmental education in the enterprise that strongly recognizes the importance of environmental communication with citizens. In other words, it can be said a leading enterprise concerning environmental education, Third, Recognition of the enterprise concerning the importance of environmental education again and the establishment of the positive posture are important.

• Journal of Korea Game Society
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• v.20 no.2
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• pp.101-112
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• 2020

This study looked into how to carry out sacrifices for intra-game cooperation in becoming a high-level player. The results are as follows. First, the way players behave is dependent on their resources(scores). Second, the higher the player's score, the more praise cards were given to dealers. Third, high-scoring players have taken on a role of "sacrificing the self to serve the many" by voluntarily playing the role of healer, leading the team to set the rules and consequently reducing the risk of a probable role conflict within the team.