• 제목/요약/키워드: lead(II)

검색결과 524건 처리시간 0.023초

복합부위통증증후군 환자에서 척수자극술과 교감신경 고주파열응고술 -증례 보고- (Thoracic Spinal Cord Stimulation and Radiofrequency Thermocoagulation of Lumbar Sympathetic Ganglion in a Patient with Complex Regional Pain Syndrome in the Lower Extremity -A case report-)

  • 김시현;문동언;박종민;유건희;서경수;유시현
    • The Korean Journal of Pain
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    • 제18권2호
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    • pp.240-245
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    • 2005
  • Herein is described the successful treatment of complex regional pain syndrome type II with the combination treatment of spinal cord stimulation and radiofrequency thermocoagulation of the lumbar sympathetic ganglion. A 62 years old male patient, suffering from CRPS type II in his left lower extremity, visited our pain clinic. Medication and nerve blockade produced only slight improvement in his symptoms and signs. Therefore, a linear type spinal cord simulator was inserted into the thoracic epidural space, using a non-surgical percutaneous approach, with the cephalad lead located at the T11 level. Two months later, the repositioning of the electrode to the T12 level for more effective pain control, with radiofrequency thermocoagulation of lumbar sympathetic ganglion also performed at the left L2 and 3 levels for the control of trophic change. These resulted in significant pain relief and decreased trophic change, with no complications, after which the patient was able to resume a normal life.

미량 중금속의 농축 및 정량을 위한 폴리에틸렌이민-폴리메틸렌폴리페닐렌 이소시안에이트에 토대한 킬레이트 수지의 합성에 관한 연구(II) : 루빈산이 결합된 카르복시메틸화된 폴리아민-폴리우레아 수지 (Studies on the Polyethylenimine-Polymethylenepolyphenylene Isocyanate Backbone Chelating Resin Synthesis for the Trace Heavy Metals Enrichment and Analysis(II) : Rubeanic Acid Loaded Carboxymethylated Polyamine-Polyurea Resin)

  • 정용순;이강우;황종연;임광수
    • 분석과학
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    • 제6권5호
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    • pp.435-442
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    • 1993
  • 루빈산이 결합된 카르복시메틸화된 폴리아민-폴리우레아(RCCPPI) 수지가 클로로카르복시메틸화된 폴리아민-폴리우레아(CCPPI) 수지와 루빈산으로부터 1단계 반응에 의하여 합성되었다. 이 수지의 구조는 적외선 분광광도법, 원소분석 및 시차열분석법으로 확인되었다. 이 수지에 대한 중금속 흡착특성은 용액의 pH를 변화시키면서 뱃치법에 의하여 분포계수($K_d$)를 측정하고, 프론탈크로마토그래피법으로 관류점을 측정하여 조사하였다. 중금속 이온용액을 이 수지로 충진된 관에 통과시킴에 의하여 고농도의 나트륨, 칼슘 및 아세트산염 용액 중에 존재하는 미량 중금속 이온을 최적 pH에서 농축 및 회수 정량할 수 있었다. 농축 인자는 25 이상이었고 흡착된 중금속들은 0.025M EDTA 용액(pH 9.0)으로 회수 정량하였다.

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Maternal selenium-supplementation at various stages of periconception period: influence on murine blastocyst morphology and implantation status

  • Mamon, Mark Anthony C.;Ramos, Gliceria B.
    • Journal of Animal Science and Technology
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    • 제59권4호
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    • pp.7.1-7.13
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    • 2017
  • Background: Selenium is one of the trace minerals whose deficiency is known to lead to complications of female reproduction. The identified gaps in researches regarding selenium and pregnancy include optimizing the dosage of selenium supplementation, timing of supplementation, finding the best form and type of selenium, and selenium administration combined with other antioxidants. Hence, this study was conceptualized to address one of the identified gaps, that is, to find out the best timing of selenium administration around the time of pregnancy. Specifically, this study aimed to assess the effects of maternal Selenium-supplementation, administered at various stages of periconception period, on murine blastocyst morphology, percent occurrence of good quality blastocysts, and implantation status. Methods: ICR female mice were randomly assigned into the unsupplemented group (Group I) receiving basal diet without selenium, and treatment groups given with $3.0{\mu}g$ selenium-supplement per day during pregestation only (Group II), pregestation-throughout-gestation (Group III) and gestation only (Group IV). Both blastocyst morphology and implantation status were assessed. Results: The morphometric measurements of blastocysts appeared to be unaffected by selenium-supplementation at different stages of periconception. Selenium-supplementation at pregestation only (Group II) and gestation only (Group IV) produced higher percent occurrence of good quality blastocysts and lower percent pre-implantation loss than Group III. Among all the treatment groups, Group III (Selenium-supplementation during pregestation-to-gestation) yielded the lowest quality blastocysts and highest percent pre-implantation loss. Conclusion: Maternal selenium-supplementation during pregestation and gestation stages of the periconception period yielded a high percent occurrence of good quality blastocysts and pre-implantation success.

강릉시 연안 문어어업에 관한 연구- II - 문어흘림낚시어업 - (Octopus fisheries in the coastal waters of Gangneung- II - Octopus drift-line fishery -)

  • 안영일;박진영
    • 수산해양기술연구
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    • 제42권2호
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    • pp.78-85
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    • 2006
  • A survey on the fishing gear for octopus drift-line fishing was done in Gangwon-do, Sacheon, Gyeongnam and Hokkaido, Japan, while a survey on the environments of fishing grounds used data from January to August from the Korea east coast farming forecast system of Donghae Fisheries Research and Development Institute. The present situation of fishing was examined with boats engaging in drift-line fishing from March to August in the coastal waters along Gangneung. The fishing tackle for octopus drift-line fishing was made manually, and the size, shape, and weight of the hook and number of shooting used vary according to the fishing time and region. Lead is used as the material for sinkers. As bait, pork fat with skin is mostly used in Gangwon-do. The temperature of the bottom water layer in the coastal fishing ground of Gangneung from April to June ranges from $3.2-12.4^{\circ}C$, which is the optimal temperature for octopuses. During July and August, the temperature ranges from $5.0-20.6^{\circ}C$. The maximum difference between day and night temperatures reached up to $9.2^{\circ}C$. Salinity is generally stable at $33.2-35.324.6%_{\circ}$, which does not affect the inhabitation of octopuses. The octopus catch reached its peak from May to July, while most octopuses weighed less than 1 kg (76.7%). The results show that it is effective to carry out octopus drift-line fishing up to a depth of 40 meters; and that the maximum number of octopuses per line is obtained with an operation time of six hours.

AMGA GUI Client 툴킷 구현 : AMGA Manager (Implementation of AMGA GUI Client Toolkit : AMGA Manager)

  • 허태상;황순욱;박근철
    • 한국콘텐츠학회논문지
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    • 제12권3호
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    • pp.421-433
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    • 2012
  • EMI gLite 미들웨어 컴포넌트인 AMGA 서비스는 과학기술 연구자들에 의해 메타데이터 저장소로 분산환경의 대규모 실험 데이터 분석에 넓게 활용되고 있고 그 사용은 메타데이터 카탈로그를 필요로 하는 일반산업에까지 확대되고 있는 추세이다. 하지만, 리눅스와 그리드 사용자 인터페이스 기반의 AMGA는 다른 상용 데이터베이스 시스템과 비교해서 범용성 사용자 인터페이스의 부재라는 단점이 있으며, 기능의 우수함에도 불구하고 활용 및 확산하는데 어려움이 있다. 본 논문에서는, AMGA 사용의 제약을 최소화하고 사용자 친화적 인터페이스를 제공하기 위해 객체지향적 모델링 언어(UML)를 이용하여 AMGA GUI 툴킷을 개발하였다. 현재 Belle II, WISDOM, MDM 등과 같이 많은 사용자 커뮤니티에서 AMGA는 주요 컴포넌트로 사용되고 있지만 본 개발을 통해 AMGA 신규 사용자의 진입장벽을 낮춰줄 수 있을 뿐만 아니라 보다 많은 커뮤니티로 확대가 기대된다.

Expression of CYP1A1 and GSTP1 in Human Brain Tumor Tissues in Pakistan

  • Wahid, Mussarat;Mahjabeen, Ishrat;Baig, Ruqia Mehmood;Kayani, Mahmood Akhtar
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7187-7191
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    • 2013
  • Most of the exogenous and endogenous chemical compounds are metabolized by enzymes of xenobiotic processing pathways, including the phase I cytochrome p450 species. Carcinogens and their metabolites are generally detoxified by phase II enzymes like glutathione-S-transferases (GST). The balance of enzymes determines whether metabolic activation of pro-carcinogens or inactivation of carcinogens occurs. Under certain conditions, deregulated expression of xenobiotic enzymes may also convert endogenous substrates to metabolites that can facilitate DNA adduct formation and ultimately lead to cancer development. In this study, we aimed to test the association between deregulation of metabolizing genes and brain tumorigenesis. The expression profile of metabolizing genes CYP1A1 and GSTP1 was therefore studied in a cohort of 36 brain tumor patients and controls using Western blotting. In a second part of the study we analyzed protein expression of GSTs in the same study cohort by ELISA. CYP1A1 expression was found to be significantly high (p<0.001) in brain tumor as compared to the normal tissues, with ~4 fold (OR=4, 95%CI=0.43-37) increase in some cases. In contrast, the expression of GSTP1 was found to be significantly low in brain tumor tissues as compared to the controls (p<0.02). This down regulation was significantly higher (OR=0.05, 95%CI=0.006-0.51; p<0.007) in certain grades of lesions. Furthermore, GSTs levels were significantly down-regulated (p<0.014) in brain tumor patients compared to controls. Statistically significant decrease in GST levels was observed in the more advanced lesions (III-IV, p<0.005) as compared to the early tissue grades (I-II). Thus, altered expression of these xenobiotic metabolizing genes may be involved in brain tumor development in Pakistani population. Investigation of expression of these genes may provide information not only for the prediction of individual cancer risk but also for the prevention of cancer.

Randomized controlled clinical trial of 2 types of hydroxyapatite-coated implants on moderate periodontitis patients

  • Kim, Hyun-Suk;Yun, Pil-Young;Kim, Young-Kyun
    • Journal of Periodontal and Implant Science
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    • 제46권5호
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    • pp.337-349
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    • 2016
  • Purpose: The aim of this study was to compare and analyze the peri-implant tissue conditions and prospective clinical outcomes associated with 2 types of hydroxyapatite (HA)-coated implants: (1) fully HA-coated implants and (2) partially HA-coated implants with resorbable blast medium on the coronal portion of the threads. Methods: Forty-four partially edentulous patients were randomly assigned to undergo the placement of 62 HA-coated implants, and were classified as the control group (partially HA-coated, n=30) and the test group (fully HA-coated, n=32). All patients had chronic periodontitis with moderate crestal bone loss around the edentulous area. The stability and clinical outcomes of the implants were evaluated using the primary and secondary implant stability quotient (ISQ), as well as radiographic, mobility, and peri-implant soft tissue assessments around the implants. The Wilcoxon signed-rank test and the Mann-Whitney test were used to evaluate differences between and within the 2 groups, with P values <0.05 considered to indicate statistical significance. Results: The fully HA-coated implants displayed good retention of crestal bone, and insignificant differences were found in annual marginal bone loss between the 2 types of HA-coated implants (P>0.05). No significant differences were found in the survival rate (group I, 100%; group II, 100%) or the success rate (group I, 93.3%; group II, 93.8%). The fully HA-coated implants also did not significantly increase the risk of peri-implantitis (P>0.05). Conclusions: The fully HA-coated implants did not lead to an increased risk of peri-implantitis and showed good retention of the crestal bone, as well as good survival and success rates. Our study suggests that fully HA-coated implants could become a reliable treatment alternative for edentulous posterior sites and are capable of providing good retention of the crestal bone.

생식생장기 냉수온이 벼의 Source와 Sink관련형질 및 양분흡수에 미치는 연구 II. 냉수관계가 벼의 엽신, 지경, 영각의 무기성분 조성에 미치는 영향 (Studies on the Growth Characters and Nutrient Uptake Related to Source and Sink by Cool Water Temperature at Reproductive Growth Stage II. Influence of Cool Water Irrigation on the Inorganic Element Content of Leaf Blades, Rachis Branches and Chaff of Rice)

  • 최수일;황창주;이중호
    • 한국작물학회지
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    • 제31권1호
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    • pp.1-8
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    • 1986
  • 냉수관계일수가 엽신, 지경, 영곡의 무기성분조성에 미치는 영향을 조사분석하였던바 다음과 같은 결과를 얻었다. 1. 엽신, 지경, 영각의 무기성분조성은 냉수관계일수가 길어질수록 전질소함량은 증가하나 인산, 가리, 규산함량조은 낮았으며 숙기별로는 전질소와 인산은 출수기 가리는 엽신과 지경에서는 출수기, 영각은 성숙기, 규산은 성숙기에 많았고 지경의 무기성분함량은 엽신보다는 영각과 유사한 양식을 나타냈다. 2. 냉수에 의해 도체가 저질소흡수과정장해를 받으면 인산, 가리, 규산도 흡수장해를 받으며 그 경향은 지경보다는 엽신과 영각의 영양장해가 현저하였으며 도체에 전질소함량이 높고 규산함량이 낮으면 지경과 영화의 퇴화 및 불임이 증가되고 지경의 영양장해가 엽신과 영각보다 퇴화 및 불임에 밀접하게 관여하였다.

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TMA-물계 포접화합물의 과냉각 억제에 대한 연구 II (A Study on Supercooling Repression of TMA-Water Clathrate Compound II)

  • 김창오;김진흥;정낙규
    • 한국에너지공학회:학술대회논문집
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    • 한국에너지공학회 2006년도 에너지.가스.기후변화학회 연합춘계학술대회 및 특별심포지움
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    • pp.317-324
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    • 2006
  • This study aims to find out cooling characteristics of TMA(Tri-Methyl-Amine, ($CH_{3})_{3}N$) 25wt%-clathrate compound with ethanol($CH_{3}CH_{2}OH$) such as supercooling, phase change temperature and specific heat. For this purpose, ethanol is added as per weight concentration and cooling experiment is performed at $-6{\sim}-8^{\circ}C$, cooling heat source temperature, and it leads the following result. (1) Phase change temperature is decreased due to freezing point depression phenomenon. Especially, it is minimized as $3.8^{\circ}C$ according to cooling source temperature in case that 0.5w% of ethanol is added. (2) If 0.5wt% of ethanol is added, average supercooling degree is $0.9^{\circ}C $ and minimum supercooling is $0.8,\;0.7^{\circ}C$ according to cooling heat source temperature. The restraint effect of supercooling is shown. (3) Specific heat shows tendency to decrease if ethanol is added. It is $3.013{\sim}3.048\;kJ/kgK$ according to cooling heat source temperature if 0.5wt% of ethanol is added. Phase change temperature higher than that of water and inhibitory effect against supercooling can be confirmed through experimental study on cooling characteristics of TMA 25wt%-water clathrate compound by adding additive, ethanol. This can lead to shorten refrigerator operation time of low temperature thermal storage system and improve COP of refrigerator and efficiency of overall system. Therefore energy can be saved and efficiency can be improved much more.

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수평축 풍력터빈의 공력 하중 비교 (II): 수직 전단흐름 효과의 유·무 (Comparison of Aerodynamic Loads for Horizontal Axis Wind Turbine (II): with and without Vertical Wind Shear Effect)

  • 김진;강승희;유기완
    • 한국항공우주학회지
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    • 제44권5호
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    • pp.399-406
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    • 2016
  • 대형 풍력터빈은 지상 전단 흐름 내에서 회전하면서 주기적인 유입속도의 변동 조건 하에 운용된다. 수직 전단흐름에 의해서 경계층 내의 유입 속도는 최고점에서 속도가 최대가 되고 최저점에서 속도가 최소가 된다. 이러한 공간적인 풍속 분포는 풍력터빈 로터의 허브와 저속회전축에서 6분력 하중에 대한 주기적인 진동을 야기한다. 본 연구에서는 수직 전단 흐름 효과를 무시한 균일 흐름장과 지상 전단 흐름효과를 고려한 두 가지 경우에 대한 공력 하중을 비교분석하였다. 계산 결과로부터 허브에서의 추력과 굽힘모멘트, LSS의 굽힘모멘트가 크게 변동하는 결과를 보여주었다. 따라서 지상 전단흐름 효과를 반영한 공력 해석이 피로 해석을 위해서 반드시 필요함을 확인하였다.