• Journal of the Korean Society of Hazard Mitigation
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• v.4 no.4 s.15
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• pp.43-54
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• 2004

The broadband receiver functions are developed from teleseismic P waveforms recorded at Wonju(KSRS), Inchon(IRIS), and Pohang(PHN), and are analyzed to examine the crustal structure beneath these stations. The teleseismic receiver functions are inverted in the time domain of the vertical P wave velocity structures beneath the stations. Clear P-to-S converted phases from the Moho interface are observed in teleseismic seismograms recorded at these stations. The crustal velocity structures beneath the stations are estimated by using the receiver function inversion method(Ammon et al., 1990). The general features of inversion results are as follows: (1) For the Inchon station, the Conrad discontinuity exists at 17.5 Km(SW) deep and the Moho discontinuity exists at 29.5 Km(NW) and 30.5 Km(SE, SW) deep. (2) The shallow crustal structure beneath Wonju station may be covered with a sedimentary rock of a 3 Km thickness. The average Moho depth is assumed about 33.0 Km, and the Conrad discontinuity may exist at 17.0 Km(NE) and 21.0 Km(NW) deep. (3) For Pohang station, the thickness of shallow sedimentary layer is a 3.0 Km in the direction of NE and NW. The Moho depth is 28.0 Km in the direction of the NE and NW. The Conrad discontinuity can be estimated to be existed at 21.0 Km deep for the NE and NW directions.

• The Journal of Engineering Geology
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• v.25 no.2
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• pp.189-199
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• 2015

Our country's leading granite weathered soil of the ground slope failures that occur in cutting slope most cases, it does not require in-depth to the shear strength most of the surface layer is affected by weathering (1~2 m) at a shallow depth close to the ground, it is important to identify the reliability. Based on the result obtained in actual field investigation, the field slope type was classified by each type of wedge slope, Infinite slope, finite slope -I and finite slope -II, and the slope stability was examined respectively. In addition, using the numerical analysis results, the relationship between the slope inclination angle and safety factor was analyzed and it tried to offer basic data to which the stability in the field slope was able to be estimated by analyzing the safety factor change of the slope according to the slope type. In this study, classified into four types of natural slope, safety factor estimation method by slope types is proposed through the numerical analysis. However, some limit exists in generalizing in this research because it does not test various case studies. Therefore, the case study of a wide range of various sypes to assess the safety of various types slope can be made, accommodate a wide range of field conditions reasonable risk evaluation criteria may be derived.

• The Journal of Engineering Geology
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• v.20 no.2
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• pp.191-202
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• 2010

In this study, the relationship between the settlements and the horizontal displacements according to embankment was analyzed at the marine sedimentary grounds for preparation of a site, and then the empirical equations of both the settlement and the horizontal displacement considering the embankment load and the thickness were proposed. To do this, the field and laboratory tests were performed at the improvement section where the pre-loading method was applied, and the field monitoring was performed using various sensors. Based on the results of the tests and monitoring, the ground deposits, soil characteristics and engineering properties were analyzed and the settlements and lateral movements were estimated by the Regression analysis. The ground deposits from the ground surface were composed of reclaimed soils, sedimentary soils and based rocks. The thickness of clay in the sedimentary soils layer was ranged from 3.9 m to 44.5 m. The embankment heights to improve the ground during pre-loading were constructed from 4.7 m to 7.8 m in each section. The settlements during embankment were ranged from 0.959 m to 2.217 m and the lateral movements were ranged from 0.048 m to 0.313 m. As the result of regression analysis, the equations of settlements and horizontal displacements according to embankments may be proposed as $s=0.02h^2+0.11h$ and ${\delta}=0.01e^{0.37h}$, respectively. The proposed empirical equations of the settlements and the horizontal displacements according to embankment on the marine sedimentary ground may be applied to the site where has a similar condition of study area.

• The Journal of Korean Society for Radiation Therapy
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• v.11 no.1
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• pp.16-21
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• 1999

Purpose : The aim of this study is to conform the possibility of the liquid type EPID as a QC tools to clinical indication and of replacement of the film dosimetry. Aditional aim is to describe a procedure for the use of a EPID as a physics calibration tool in the measurements of radiation beam parameters which are typically carried out with film. Method & Materials : In this study we used the Clinac 2100c/d with EPID. This system contains 65536 liquid-filled ion chambers arranged in a $256{\times}256$ matrix and the imaging area is $32.5{\times}32.5cm$ with liquid layer thickness of 1mm. The EPID was tested for different field sizes under typical clinical conditions and pixel values were calibrated against dose by producing images using various thickness of lead attenuators(lead step wedge) using 6 & 10MV x-ray. We placed various thickness of lead on the table of linear accelerator and set the portal vision an SDD of 100cm. To acquire portal image we change the field size and energy, and we recorded the average pixel value in a $3{\times}3$ pixel region of interest(ROI) at field center was recorded. The pixel values were also measured for different field sizes in order to evaluate the dependence of pixel value on x-ray energy spectrum and various scatter components. Result : The EPID, as a whole, was useful as a QA tool and dosimetry device. In mechanical check, cross-hair centering was well matched and the error was less than ?2mm and light/radiation field coincidence was less than 1mm also. In portal dosimetry the wider the field size the the higher the pixel value and as the lead thickness increase, the pixel value was exponentially decreased. Conclusions : The EPID was very suitable for QA tools and it can be used to measure exit dose during patients treatment with reasonable accuracy. But when indicate the EPID to clincal study deep consideration required

• Atmosphere
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• v.20 no.1
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• pp.37-47
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• 2010

The methods measuring the precipitation drop size distribution(hereafter referred to as DSD) at Cloud Physics Observation System (CPOS) in Daegwallyeong are to use PARSIVEL (PARticle SIze and VELocity) disdrometer (hereafter referred to as PARSIVEL) and Micro Rain Radar (hereafter referred to as MRR). First of all, PARSIVEL and MRR give good correlation coefficients between their rain rates and those of rain gage: $R^2=0.93$ and 0.91, respectively. For the DSD, the rain rates are classified in 3 categories (Category 1: rr (Rain Rate) ${\leq}0.5\;mm\;h^{-1}$, Category 2: $0.5\;mm\;h^-1$ < rr < $4.0\;mm\;h^{-1}$, Category 3: rr ${\geq}4\;mm\;h^{-1}$). The shapes of PARSIVEL and MRR DSD are relatively most similar in category 2. In addition, we retrieve the vertical rain rate and liquid water content from MRR under melting layer, calculated by Cha et al's method, in Daegwallyeong ($37^{\circ}41{\prime}N$, $128^{\circ}45^{\prime}E$, 843 m ASL, mountain area) and Haenam ($34^{\circ}33^{\prime}N$, $126^{\circ}34^{\prime}E$, 4.6 m ASL, coast area). The vertical variations of rain rate and liquid water content in Daegwallyeong are smaller than those in Haenam. We think that this different vertical rain rate characteristic for both sites is due to the vertical different cloud type (convective and stratiform cloud seem dominant at Haenam and Daegwallyeong, respectively). This suggests that the statistical precipitation DSD model, for the application of weather radar and numerical simulation of precipitation processes, be considered differently for the region, which will be performed in near future.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.3
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• pp.551-565
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• 2017

A spray-applied waterproofing membrane which consists of polymers has a relatively higher constructability and adhesion than the conventional sheet-type waterproofing materials. Additionally, the spray-applied waterproofing membrane generally shows a waterproofing ability as a composite structure with shotcrete or concrete lining. Because its purpose is waterproofing at the structure, structural effects were not well reported than waterproofing abilities. In this study, structural effects of the membrane-attached concrete lining were evaluated using 3-point bending test by the numerical method. From the analysis, a load-displacement behavior of the concrete lining and fracturing energy after yielding were compared with various conditions. Consequently, concrete lining with spray-applied waterproofing membrane shows higher flexural strength and fracturing energy than the single-layer concrete lining.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.8
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• pp.993-999
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• 2010

Serum lysozyme gene is one of the important genes influencing the immune system as its product can cause lysis of bacterial cell wall by cleaving the peptidoglycan layer. The present investigation on the serum lysozyme gene of Indian riverine buffalo was undertaken with the objectives to identify and characterize single nucleotide polymorphic patterns by PCR-SSCP method as well as to study the effect of different genotypes on serum lysozyme activity and somatic cell count. A total of 280 animals comprising four different famous bubaline breeds (Murrah, Mehsana, Surti and Bhadawari), spread over six different farms across the country were used for this study. A 276 bp (partial intron 2, complete exon 3 and partial intron 3) fragment of lysozyme gene was screened for polymorphism using the SSCP technique. Four genotypes namely AA, AB, BC and AC were observed, out of which BC genotype was found to be the most frequent. Among these three alleles, C allele (0.38) was most prevalent in these populations. Various SSCP allelic variants were cloned for sequencing and sequences were submitted to NCBI Genbank. From the alignment of the nucleotide sequences of various allelic variants, it was found that there were differences in 12 positions among the alleles, out of which maximum variation (at 8 places) was found in the intronic region. The allele A was closer to allele-C than allele-B. Allele B was phylogenetically equidistant from both of the other alleles. Mean lysozyme activity determined in serum samples of different animals of Murrah buffalo was $27.35{\pm}2.42\;{\mu}g$ per ml of serum, whereas the mean somatic cell count was $1.25{\pm}0.13{\times}10^5$ cells per ml of milk. The SSCP pattern-wise effects of various genotypes on lysozyme activity and SCC were analyzed. Although the mean values were apparently different in various genotypes, these differences were statistically non-significant. It can be concluded that the riverine buffaloes are sufficiently polymorphic with respect to serum lysozyme gene. The absence of AA genotype in Bhadawari breed of buffalo can be considered as a marker for breed characterization. The difference of four nucleotides in exon-3 indicates high selection pressure on the gene.

• Microbiology and Biotechnology Letters
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• v.10 no.4
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• pp.267-273
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• 1982

Among 12 kinds of ginsenosides in ginseng saponin, ginsenoside-Rb$_1$was contained the most abundantly. But ginsenoside-Rd which is similar to ginsenoside-Rb$_1$in structure, was known to be superior to ginsenoside-Rb$_1$pharmaceutically. In order to convert ginsenoside-Rb$_1$into ginsenoside-Rd by microbial enzyme treatment, a Rhizopus sp. was selected among various strais of molds found in rotten ginseng roots. Enzyme was prepared from the extract of wheat bran koji culture by ammonium sulfate precipitation (1.0 sat'd) and succeeding ammonium sulfate fractionation method (0.6-0.9 sat'd). For the purpose of use as substrate, saponins were purified by the several purification steps from alcohol extract of red ginseng roots. We obtained the total saponin which was composed of 36.5% of ginsenoside Rb$_1$, 12.2% of ginsenoside-Rd and other ginsenosides. For increase of ginsenoside-Rb$_1$ component ratio, we also obtained further purified ginsenoside-Rb group saponin containing 54.5% of ginsenoside-Rb$_1$, 1.1% of ginsenoside- Rd and other ginsenosides from purified the total saponin. In the enzymatic reaction system including the total saponin or the ginsenoside-Rb group saponin, we confirmed the specific conversion of ginsenoside-Rb$_1$to ginsenoside-Rd proportionally and no change of any other ginsenoside patterns by thin layer chromatography and high performance liquid chromatography.

• Journal of Powder Materials
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• v.24 no.3
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• pp.195-201
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• 2017

In this study, H13 tool steel sculptures are built by a metal 3D printing process at various laser scan speeds. The properties of commercial H13 tool steel powders are confirmed for the metal 3D printing process used: powder bed fusion (PBF), which is a selective laser melting (SLM) process. Commercial H13 powder has an excellent flowability of 16.68 s/50 g with a Hausner ratio of 1.25 and a density of $7.68g/cm^3$. The sculptures are built with dimensions of $10{\times}10{\times}10mm^3$ in size using commercial H13 tool steel powder. The density measured by the Archimedes method is $7.64g/cm^3$, similar to the powder density of $7.68g/cm^3$. The hardness is measured by Rockwell hardness equipment 5 times to obtain a mean value of 54.28 HRC. The optimum process conditions in order to build the sculptures are a laser power of 90 W, a layer thickness of $25{\mu}m$, an overlap of 30%, and a laser scan speed of 200 mm/s.

• Journal of Pharmaceutical Investigation
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• v.35 no.6
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• pp.417-422
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• 2005

This study was aimed to design and formulate the moisture-activated patches containing ofloxacin and lidocaine for antibacterial and local anesthetic action. The solubility of lidocaine at $32^{\circ}C$ in various vehicles decreased in the rank order of PG $759.5{\pm}44.5\;mg/mL$ > PGL > IPM > PEG 300 > PEG 400 > Ethanol > PGMC > DGME > PGML > OA > $Captex^{\circledR}\;300$ > $Captex^{\circledR}\;200$ > water $(4.0{\pm}0.1\;mg/mL)$. Ofloxacin revealed very low solubility, which the highest solubility was obtained from PEG 400 $(18.7{\pm}6.3\;mg/mL)$ among the vehicles used. The addition of lactic acid increased the solubility of ofloxacin dramatically; the solubility at 5% lactic acid was $133.7{\pm}9.7\;mg/mL$. As $2-hydroxypropyl-{\beta}-cyclodextrin$ was added at the concentrations of 40, 80, 120, 160 and 200 mM, the solubilities of lidocaine and ofloxacin were enhanced up to three and two times, respectively, with concentration-dependent pattern. Gel intermediates for filmtype patches were prepared with mucoadhesive polymer, viscosity builders, lidocaine or ofloxacin at pH values from 5 to 7. Gels were cast onto a release liner and dried at room temperature. Dried patch was attached onto an adhesive backing layer, thus forming a patch system. Patches containing a single drug component were characterized by in vitro measurement of drug release rates through a cellulose barrier membrane. The release study was carried out at $37^{\circ}C$ using a Franz-type cell. Receptor solutions were isotonic phosphate buffers (pH 7.4). Samples $(100\;{\mu}L)$ were taken over 24 hours and quantitated by a verified HPLC method. The releases from all tested were proportional to the square root of time. The release rates were 0.9, 157.3 and $281.7\;{\mu}g/cm^{2}/min^{1/2}$ for the lidocaine patches and 19.8,37.2 and $50.7\;{\mu}g/cm^{2}/min^{1/2}$ for the ofloxacin patches at the concentrations of 0.3, 0.5 and 1 %, respectively. The release rates were dose dependent in both drug patches $(R^{2}\;=\;0.9077\;for\;lidocaine;\;R^{2}\;=\;0.9949\;for\;ofloxacin)$ and those were also thickness-dependent $(R^{2}\;=\;0.9246\;for\;lidocaine;\;R^{2}\;=\;0.9512\;for\;ofloxacin)$.