• 약학회지
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• 제51권6호
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• pp.490-494
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• 2007

TRH (thyrotropin-releasing hormone) was chemically synthesized utilizing solution phase peptide chemistry for the process development of large scaled synthesis. All the synthetic steps performed in relatively mild conditions, higher yields, easier preparations, minimum racemizations, and separation and purification by recrystallizations.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 1996년도 추계학술대회논문집; 한국과학기술회관, 8 Nov. 1996
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• pp.224-230
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• 1996

In the mechanical systems with large damping, the conventional SDM method developed for no damping systems will lead to an error solution. Here, we introduce a SDM method based on the experimental modal model for large damping systems. The sensitivities of natural frequencies and mode shapes with respect to mass, damping, and stiffness coefficients of structures are used to calculate the position and quantity of modification, and predict the new dynamic characteristics. Through numerical simulation and experiment, the effectiveness of the proposed method is tested.

• 반도체디스플레이기술학회지
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• 제21권3호
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• pp.125-129
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• 2022

The current display technology tends to be highly integrated with high resolution, the element size is gradually downsized, and the structure becomes complicated. Inductively coupled plasma (ICP) dry etcher of various types of etching equipment is a structure that places a large multi-divisional antenna source on the top lid, passes current to the Antenna, and generates plasma using the induced magnetic field generated at this time. However, in the case of a device of a large area size, a support that can withstand a load structurally is necessary, and when these support portions are applied, arrangement of antenna becomes difficult, which causes reduction in uniformity. As described above, the development of antenna source of a large area having a uniform plasma density on the whole surface is difficult to restrict hardware (H/W). As a solution to this problem, we confirmed the change in uniformity of plasma by applying two kinds of specific shape faraday shield(FICP) to the lower part of the large area upper lid antenna of 6 and 8th more than that generation size. In this thesis, we verify the faraday shield effect which can improve plasma uniformity control of ICP dry etcher equipment applied to medium and large displays.

• International Journal of Precision Engineering and Manufacturing
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• 제8권1호
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• pp.3-10
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• 2007

A new approach based on implicit surface interpolation combined with domain decomposition is proposed for filling complex-shaped holes in a large polygon model, A surface was constructed by creating a smooth implicit surface from an incomplete polygon model through which the actual surface would pass. The implicit surface was defined by a radial basis function, which is a continuous scalar-value function over the domain $R^{3}$. The generated surface consisted of the set of all points at which this scalar function is zero. It was created by placing zero-valued constraints at the vertices of the polygon model. The well-known domain decomposition method was used to treat the large polygon model. The global domain of interest was divided into smaller domains in which the problem could be solved locally. The LU decomposition method was used to solve the set of small local problems; the local solutions were then combined using weighting coefficients to obtain a global solution. The validity of this new approach was demonstrated by using it to fill various holes in large and complex polygon models with arbitrary topologies.

• 한국정밀공학회지
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• 제17권2호
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• pp.201-210
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• 2000

The large deflection of plate is analyzed by co-rotational formulations using small local displacements and rotating unit vectors on the nodal points. The rotational degrees of the freedom are represent ed by the unit vectors1 In the nodal points, and the equilibrium equations are formulated by using small deflection theories of the plates by assuming that the directions of the unit vectors of the nodal points are known apriori. The translational degrees of freedom are independently solved from the rotational degrees of freedom in the equilibrium equations, and the correct directions of the unit vectors are computed by the iterative scheme by imposing the moment equilibrium constraint. The equilibrium equations and the associated solution procedure are explained, and the verification problems are solved.

• 한국경영과학회지
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• 제38권4호
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• pp.65-78
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• 2013

Circular shareholding is established when at least three member firms in a business group hold stock in other member firms and form a series of ownership in a circular way. Although there have been many studies which investigated a negative effect of circular shareholding on firm's value, few studies have discussed how to resolve the problem given complicated ownership structures of large business groups. This paper is based on a mixed integer programming model, which was proposed in the author's previous research and can identify the ownership share divested in order to resolve circular shareholding. Since the optimization model becomes too complicated for large business groups and requires a sophisticated software to solve it, we propose a simple heuristic method that can find a good approximate solution to the model. Its applications to twelve Korean large business groups show that the heuristic method is not just computationally attractive but also provides near-optimal solutions in most cases.

• 한국경영과학회지
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• 제21권1호
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• pp.1-17
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• 1996

There have been considerable researches for solving large-scale separable convex optimization ptoblems. In this paper we present a method for large-scale nonseparable smooth convex optimization problems with block-angular linear constraints. One of them is occurred in reconfiguration of the virtual path network which finds the routing path and assigns the bandwidth of the path for each traffic class in ATM (Asynchronous Transfer Mode) network [1]. The solution is approximated by solving a sequence of the block-angular structured separable quadratic programming problems. Bundle-based decomposition method [10, 11, 12]is applied to each large-scale separable quadratic programming problem. We implement the method and present some computational experiences.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2006년도 춘계 학술발표회 논문집
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• pp.697-702
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• 2006

A counterplan of slope failure has to investigate about various and engineering safety factors. Especially, it is important that large cut-slope must examine rational and economic solution. In this case study, cut-slope failure caused by inflow of rainwater into alternate layers. Hereafter it is suggested that large cut-slope should consider analysis the cause for a decline of safety factor and the engineering character of corestone ground mass.

• Journal of applied mathematics & informatics
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• 제9권1호
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• pp.61-76
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• 2002

The robust non-fragile guaranteed cost control problem is studied in this paper for class of uncertain linear large-scale systems with time-varying delays in subsystem interconnections and given quadratic cost functions. The uncertainty in the system is assumed to be norm-hounded arid time-varying. Also, the state-feedback gains for subsystems of the large-scale system are assumed to have norm-bounded controller gain variations. The problem is to design state feedback control laws such that the closed-loop system is asymptotically stable and the closed-loop cost function value is not more than a specified upper bound far all admissible uncertainties. Sufficient conditions for the existence of such controllers are derived based on the linear matrix inequality (LMI) approach combined with the Lyapunov method. A parameterized characterization of the robust non-fragile guaranteed cost contrellers is 7iven in terms of the feasible solution to a certain LMI. Finally, in order to show the application of the proposed method, a numerical example is included.

• Journal of information and communication convergence engineering
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• 제19권3호
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• pp.155-160
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• 2021

Differential evolution is an efficient algorithm for solving continuous optimization problems. However, its performance deteriorates rapidly, and the runtime increases exponentially when differential evolution is applied for solving large-scale optimization problems. Hence, a novel cooperative coevolution differential evolution based on Spark (known as SparkDECC) is proposed. The divide-and-conquer strategy is used in SparkDECC. First, the large-scale problem is decomposed into several low-dimensional subproblems using the random grouping strategy. Subsequently, each subproblem can be addressed in a parallel manner by exploiting the parallel computation capability of the resilient distributed datasets model in Spark. Finally, the optimal solution of the entire problem is obtained using the cooperation mechanism. The experimental results on 13 high-benchmark functions show that the new algorithm performs well in terms of speedup and scalability. The effectiveness and applicability of the proposed algorithm are verified.