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Two adolescent patients with coexistent Graves' disease and Moyamoya disease in Korea

  • Cheon, Chong Kun;Kim, Su Yung;Yoo, Jae-Ho
    • Clinical and Experimental Pediatrics
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    • v.57 no.6
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    • pp.287-291
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    • 2014
  • Moyamoya disease is a cerebrovascular condition that results in the narrowing of the vessels of the circle of Willis and collateral vessel formation at the base of the brain. Although relationships between Graves' disease and cerebrovascular accidents in Moyamoya disease are obscure, the coexistence of the two diseases is noteworthy. Moyamoya disease has been rarely reported in adolescent patients with thyrotoxicosis. Recently, we encountered two adolescent Korean patients with Moyamoya disease associated with Graves' disease who presented with episodic right-sided hemiparesis and syncope. These two girls who had Graves' disease had no history of other diseases or head trauma. A thyroid function test revealed a euthyroid state and a high thyroid-stimulating hormone (TSH) receptor antibody titer at that time. The patients were diagnosed with Moyamoya disease based on brain magnetic resonance angiography and cerebral four-vessel angiography. The patients underwent cranial revascularization by encephalo-duroarterio-synangiosis as soon as a diagnosis was made, which resulted in successful symptom resolution. They fared well and had no additional neurological symptoms as of their last follow-up visits. Here, we report these two cases of confirmed Moyamoya disease complicated by Graves' disease with a review of the literature, and discuss the possible association between the two diseases. To our knowledge, this is the first report in South Korea on Moyamoya disease associated with Graves' disease in adolescents with a euthyroid.

A Case on Risperidone-Induced Tardive Dyskinesia (Risperidone 유발 지연성 운동장애 1례(一例))

  • Kim, Hun-Soo;Kim, Hyun-Sil;Min, Byung-Kun
    • Korean Journal of Biological Psychiatry
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    • v.5 no.1
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    • pp.129-133
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    • 1998
  • Objective : Base on clinical practice, the authors report a case of tardive dyskinesia arising during the course of treatment with resperidal. Methods : This article was review and analysis of a case on risperidone-induced tardive dyskinea. Results : Mrs K, a 51-year-old woman with a 1-year history of schizophrenic disorder, gradually developed tardive dyskinetic movement of the mouth, lip, and tongue over a 4 month period(From July, 1996 to June, 1997) while taking risperidone. Initially she was treated with haloperidol and alprazolam. However, the haloperidol was subsequently discontinued because of EPS developed. From 11th March, 1997, she was observed to have a severe form of tardive dyskinesia involving her tongue, lip, and mouth. After risperidone was withdrawn at 9th May 1997, her tardive dyskinetic movement was disappeared. Conclusions : This is, to our knowledge, the first report of the onset of tardive dyskinesia in a patient taking risperidone. However, additional controlled studies of specific questions are needed ; e.g., the dose-response curves for produce tardive dyskinesia and the mechanism of producing risperidone-induced tardive dyskinea and so on.

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Development of a Reverse Engineering System for Stamping Die Manufacturing (자동차 금형 Reverse Engineering 을 위한 측정 및 분석 시스템 개발)

  • 김덕영;노상도;한형상;주영관;박진수
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.11a
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    • pp.277-280
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    • 2000
  • Reverse Engineering is a procedure where the results of engineering decisions in manufacturing is feedback to the design phase and the knowledge-base is generated from the process know-how to reduce the errors. Since it used to take lots of time and efforts to finalize the machining of dies out of the original CAD design especially for die spotting and try-outs, reverse engineering is important to improve the productivity and quality of the die manufacturing process. In this regard, we developed system to support reverse engineering in machining of stamping dies for auto-body production. They automatically generate the relevant MC programs for a CMM simply with the input of measuring points in CAD environments, and show the CAD model and the results of inspection simultaneously for the ease of comparison. They also help reduce the overall clearance between the lower and upper dies. Applying these systems to the machining process of stamping dies, we could improve the reliability of measuring and get the optimal compensation distance between the two dies. We also analyzed the expected benefits of the system in terms of savings in time and costs.

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A Stochastic Control for Nonlinear Systems under Random Disturbance Based on a Fluid Motion (유체운동에 의한 불규칙 가진을 받는 비선형계의 확률제어)

  • Oh, Soo-Young;Kim, Yong-Kwan;Cho, Lae-Kyoung;Choi, Young-Seob;Heo, Hoon
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2001.05a
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    • pp.892-896
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    • 2001
  • Investigation is performed on the stability of nonlinear system under turbulent fluid motion modelled as white noise random process, which is a preliminary result in the course of research on the characteristic and nonlinear control of the stochastic system. Adopted physical model is beam-type structure with tip-mass and main base mass. The governing equation is derived via F-P-K approach in stochastic sense. By means of Gaussian Closure method infinite dynamic moment equations due to system nonlinearity is closed to finite one. At the best of authors' knowledge, it is the first trial to design nonlinear controller by using of sliding mode technique in stochastic domain and control performance and effect in stochastic domain is studied.

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Deformation-based vulnerability functions for RC bridges

  • Elnashai, A.S.;Borzi, B.;Vlachos, S.
    • Structural Engineering and Mechanics
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    • v.17 no.2
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    • pp.215-244
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    • 2004
  • There is an ever-increasing demand for assessment of earthquake effects on transportation structures, emphasised by the crippling consequences of recent earthquakes hitting developed countries reliant on road transportation. In this work, vulnerability functions for RC bridges are derived analytically using advanced material characterisation, high quality earthquake records and adaptive inelastic dynamic analysis techniques. Four limit states are employed, all based on deformational quantities, in line with recent development of deformation-based seismic assessment. The analytically-derived vulnerability functions are then compared to a data set comprising observational damage data from the Northridge (California 1994) and Hyogo-ken Nanbu (Kobe 1995) earthquakes. The good agreement gives some confidence in the derived formulation that is recommended for use in seismic risk assessment. Furthermore, by varying the dimensions of the prototype bridge used in the study, and the span lengths supported by piers, three more bridges are obtained with different overstrength ratios (ratio of design-to-available base shear). The process of derivation of vulnerability functions is repeated and the ensuing relationships compared. The results point towards the feasibility of deriving scaling factors that may be used to obtain the set of vulnerability functions for a bridge with the knowledge of a 'generic' function and the overstrength ratio. It is demonstrated that this simple procedure gives satisfactory results for the case considered and may be used in the future to facilitate the process of deriving analytical vulnerability functions for classes of bridges once a generic relationship is established.

Discriminant Factors of Attitude Pattern toward Sexual Violence of College Women (여대생의 성폭력 태도유형의 판별 요인)

  • Sung, Mi-Hae;Lim, Young-Mi
    • Women's Health Nursing
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    • v.15 no.4
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    • pp.312-319
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    • 2009
  • Purpose: The purpose of this study was to determine the discriminant factors of attitude pattern toward sexual violence of college women. Methods: A cross-sectional research design with non-probability samples was conducted. A total of 292 college women participated. The instruments were Attitude Pattern toward Sexual Violence, Self-Esteem Scale, Gender Role Scale, and Attitude toward Sexuality. Dependent variable is Attitude Pattern toward Sexual Violence, which is composed of two groups; cases either harmer blame or sufferer blame. Independent variables were self-esteem, attitude toward gender role, and attitude toward sexuality. Data were analyzed by SPSS WIN program and descriptive analysis, $x^2$-test, and discriminant analysis. Results: To assess the adequacy of classification, the overall hit ratio was 68.5%, and the significant predictor variable was attitude toward sexuality. Conclusion: Replication of the study needs to be considered to further enrich the specific knowledge base regarding attitude toward sexual violence among college women.

A Study on the Concept about Communicable Disease of Preschool Children (학령전 아동의 전염병 개념에 관한 연구)

  • Kim, Il-Ok;Ahn, Jae-Hyun
    • Korean Parent-Child Health Journal
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    • v.1
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    • pp.115-126
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    • 1998
  • It is the base of the health through life, the health of children is very important. The health education is the most effective measure for disease prevention and health promotion. To educate children for the health, we must consider their concept of the health before. Therefore I attempted this study for investigation for the concept about respiratory communicable disease which is one of the most important health problems. The design of this study was descriptive investigational study. The subjects of this study are 4-6 aged 65 children who are attending district nursery school. The tools of this study constituted 3 parts as an etiological agents, environmental agents and host agents. The data were collected by an individual interview and cartoon cards. The results of this study are as followed: 1. The preschool children tend to think contamination along the physical distance, nearer things more relational. 2. The preschool children tend to have their experience centered thinking. 3. There was a highly significant correlation between the children's age and knowledge scores(r = 0.431, P= 0.0003). 4. There wasn't a significant correaltion between sex group. In conclusion, it wad founded that the preschool have a tendancy to think communicable disease along the physical distance and their daily life experiences. This results support the Piaget's cognitive developmental theory. Therefore, to develop the health education program for preschool students, above results must be referenced.

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An Intelligent Agent System using Multi-View Information Fusion (다각도 정보융합 방법을 이용한 지능형 에이전트 시스템)

  • Rhee, Hyun-Sook
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.12
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    • pp.11-19
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    • 2014
  • In this paper, we design an intelligent agent system with the data mining module and information fusion module as the core components of the system and investigate the possibility for the medical expert system. In the data mining module, fuzzy neural network, OFUN-NET analyzes multi-view data and produces fuzzy cluster knowledge base. In the information fusion module and application module, they serve the diagnosis result with possibility degree and useful information for diagnosis, such as uncertainty decision status or detection of asymmetry. We also present the experiment results on the BI-RADS-based feature data set selected form DDSM benchmark database. They show higher classification accuracy than conventional methods and the feasibility of the system as a computer aided diagnosis system.

Korea's Logistics Education and Certification System to Support Globalization (글로벌 시대의 물류전문인력 육성 과제)

  • 안승범
    • Journal of Korea Port Economic Association
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    • v.17 no.2
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    • pp.89-110
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    • 2001
  • Recent trends in globalization and informatization underscore the importance of logistics. As a result, there is a need for skilled and specialized logisticians. Third Party Logistics (TPL) and Supply Chain Management (SCM) require logisticians with a broad base of knowledge in areas such as multimodal transport, international trade, information technology computers, finance, operations management, etc. This study conducted a survey to find out the opinions of demanders and suppliers. The results of the surrey show that there are more skilled logisticians in the field of management, computer works in manager level and system management. The survey also found that the certificate exam, which the Ministry of Construction and Transportation started in 1997 as the "Certified Logistics Manager" exam, should have more questions in areas such as foreign languages, computers, logistics information, management skills, etc. To produce better logisticians in Korea, the government will have to invest more into their education, especially near the major ports and metropolitan areas. In addition, it is important that universities and companies work together to provide students with internship and other field-experience teaming opportunities. Logistics education centers should be built at the national level. In addition, the existing certification should be divided into two separate certifications: one for ordinary logistics, and one for international logistics. To further improve the certification system, short-answer or essay questions should be added to the second exam, and an additional certification for the highest level logisticians, a so-called "professional logisticians certificate," needs to be introduced.ntroduced.

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A Design of Knowledge Base for the Service of Collaboration Support between Researchers (연구자 간 협업 지원 서비스를 위한 지식 베이스 설계)

  • Jung, Han-Min;Sung, Won-Kyung;Park, Dong-In
    • Annual Conference on Human and Language Technology
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    • 2005.10a
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    • pp.173-178
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    • 2005
  • 지식 베이스는 대량의 인적 물적 자원을 투입하고 철저한 설계에 기반하여 구축하여야 하는 부담이 큰 자원이다. 그렇지만, 지식 베이스 없이 다양한 응용 분야와 서비스를 만족시키는 시스템을 구축할 수 없기 때문에 그 중요성을 인정하지 않을 수 없다. 기존의 지식베이스 구축에 있어서 간과했던 것들의 하나는 응용 분야와 서비스를 명확히 하고, 해당분야에 안는 지식 베이스를 선택해야 한다는 것이다. 어휘의미망을 포함하여 시소러스를 범용 또는 여러 분야에서 구축하고 있으나 이들이 어떤 서비스에 도움이 되는지를 확실히 분석하지 못함으로 인해 응용 시스템에서 제 기능을 다하지 못하고 있으며, 온톨로지 또한 근본적으로 분야와 활용 목적에 의존적이어서 이를 고려하여 설계를 하지만 시소러스나 용어 사전과 같은 기본적인 지식 베이스와의 연계를 통한 효율성 재고라는 측면에서 약점을 보여왔다. 본 연구에서는 사용자 질의와 실 데이터간의 어휘 불일치 해소를 위해 시소러스를 설계 구축하고 온톨로지의 사례화 결과인 인스턴스와 연동시킴으로써 연구자 간 협업 지원 서비스를 제공할 수 있는 기반 자원으로서의 지식 베이스 구축에 초점을 둔다.

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