• Title/Summary/Keyword: key pool

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Analysis and Characterization of Glutathione Peroxidases in an Environmental Microbiome and Isolated Bacterial Microorganisms

  • Yun-Juan Bao;Qi Zhou;Xuejing Yu;Xiaolan Yu;Francis J. Castellino
    • Journal of Microbiology and Biotechnology
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    • v.33 no.3
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    • pp.299-309
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    • 2023
  • Glutathione peroxidases (Gpx) are a group of antioxidant enzymes that protect cells or tissues against damage from reactive oxygen species (ROS). The Gpx proteins identified in mammals exhibit high catalytic activity toward glutathione (GSH). In contrast, a variety of non-mammalian Gpx proteins from diverse organisms, including fungi, plants, insects, and rodent parasites, show specificity for thioredoxin (TRX) rather than GSH and are designated as TRX-dependent peroxiredoxins. However, the study of the properties of Gpx in the environmental microbiome or isolated bacteria is limited. In this study, we analyzed the Gpx sequences, identified the characteristics of sequences and structures, and found that the environmental microbiome Gpx proteins should be classified as TRX-dependent, Gpx-like peroxiredoxins. This classification is based on the following three items of evidence: i) the conservation of the peroxidatic Cys residue; ii) the existence and conservation of the resolving Cys residue that forms the disulfide bond with the peroxidatic cysteine; and iii) the absence of dimeric and tetrameric interface domains. The conservation/divergence pattern of all known bacterial Gpx-like proteins in public databases shows that they share common characteristics with that from the environmental microbiome and are also TRX-dependent. Moreover, phylogenetic analysis shows that the bacterial Gpx-like proteins exhibit a star-like radiating phylogenetic structure forming a highly diverse genetic pool of TRX-dependent, Gpx-like peroxidases.

Analysis of Left Ventricular Diastolic Function in Coronary Artery Disease with Gated Blood Pool Scan (관상동맥질환에서 Gated Blood Pool Scan을 이용한 좌심실 확장기능의 분석)

  • Choi, Chang-Woon;Lim, Sang-Moo;Chung, June-Key;Lee, Myung-Chul;Park, Young-Bae;Seo, Joung-Don;Lee, Young-Woo;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.20 no.2
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    • pp.39-45
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    • 1986
  • Resting gated blood pool scan was used to derive left ventricular functional changes in normals (N=13, mean age=43) and in patients with coronary artery disease (N=50, mean age=53). Peak filling rates, average filling rates, and ejection fractions were significantly depressed in coronary artery disease. (p<0.0005, each other). And in coronary artery disease with normal ejection fraction (N=21), peak filling rates and average filling rates were depressed also, and peak filling rates of coronary artery disease with normal ejection fraction were abnormal in 61.2% and average fillin rates were abnormal in 71.4%. It appears that (1) resting peak filling rates and average filling rates were sensitive and easily obtainable parameters of the diastolic dysfunction assosiated with coronary artery disease, (2) a significant proportion of coronary artery disease patients without any evidence of abnormal systolic function have depressed resting peak filling rates and average filling rates of the left ventricle.

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A Study of Fronthaul Networks in CRANs - Requirements and Recent Advancements

  • Waqar, Muhammad;Kim, Ajung;Cho, Peter K.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.10
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    • pp.4618-4639
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    • 2018
  • One of the most innovative paradigms for the next-generation of wireless cellular networks is the cloud-radio access networks (C-RANs). In C-RANs, base station functions are distributed between the remote radio heads (RHHs) and base band unit (BBU) pool, and a communication link is defined between them which is referred as the fronthaul. This leveraging link is expected to reduce the CAPEX (capital expenditure) and OPEX (operating expense) of envisioned cellular architectures as well as improves the spectral and energy efficiencies, provides the high scalability, and efficient mobility management capabilities. The fronthaul link carries the baseband signals between the RRHs and BBU pool using the digital radio over fiber (RoF) based common public radio interface (CPRI). CPRI based optical links imposed stringent synchronization, latency and throughput requirements on the fronthaul. As a result, fronthaul becomes a hinder in commercial deployments of C-RANs and is seen as one of a major bottleneck for backbone networks. The optimization of fronthaul is still a challenging issue and requires further exploration at industrial and academic levels. This paper comprehensively summarized the current challenges and requirements of fronthaul networks, and discusses the recently proposed system architectures, virtualization techniques, key transport technologies and compression schemes to carry the time-sensitive traffic in fronthaul networks.

Study on the Oxidation Treatment of Nanoparticles for the Critical Heat Flux (임계열유속 향상을 위한 나노물질의 산화처리에 대한 연구)

  • Kim, Woo-Joong;Jeon, Yong-Han;Kim, Nam-Jin
    • Journal of the Korean Solar Energy Society
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    • v.37 no.6
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    • pp.39-49
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    • 2017
  • Pool boiling, one of the key thermal-hydraulics phenomena, has been widely studied for improving heat transfer efficiencies and safety of nuclear power plants, refrigerating systems, solar-collector heat pipes, and other facilities and equipments. In the present study, the critical heat flux (CHF) and heat-transfer coefficients were tested under the pool-boiling state using graphene M-5 and M-15 nanofluids as well as oxidized graphene M-5 nanofluid. The results showed that the highest CHF increase for both graphene M-5 and M-15 was at the 0.01% volume fraction and, moreover, that the CHF-increase ratio for small-diameter graphene M-5 was higher than that for large-diameter graphene M-15. Also at the 0.01% volume fraction, the oxidized graphene M-5 nanofluid showed a 41.82%-higher CHF-increase ratio and a 26.7%-higher heat-transfer coefficient relative to the same nanofluid without oxidation treatment at the excess temperature where the CHF of distilled water occurs.

Microhabitat Characteristics Determine Fish Community Structure in a Small Stream (Yudeung Stream, South Korea)

  • Choi, Jong-Yun;Kim, Seong-Ki;Kim, Jeong-Cheol;Lee, Hyeon-Jeong;Kwon, Hyo-Jeong;Yun, Jong-Hak
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.2 no.1
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    • pp.53-61
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    • 2021
  • Distribution of fish community depends largely on environmental disturbance such as habitat change. In this study, we evaluated the impact of environmental variables and microhabitat patch types on fish distribution in Yudeung Stream at 15 sites between early May and late June 2019. We used non-metric multidimensional scaling to examine the distribution patterns of fish in each site. Gnathopogon strigatus, Squalidus gracilis majimae, Zacco koreanus, and Zacco platypus were associated with riffle and boulder areas, whereas Iksookimia koreensis, Acheilognathus koreensis, Coreoleuciscus splendidus, Sarcocheilichthys nigripinnis morii, and Odontobutis interrupta were associated with large shallow areas. In contrast, Cyprinus carpio, Carassius auratus, Lepomis macrochirus, and Micropterus salmoides were found at downstream sites associated with large pool areas, sandy/clay-bottomed areas, and vegetated areas. On the basis of these results, we suggest that microhabitat patch types are important in determining the diversity and abundance of fish communities, since a mosaic of different microhabitats supports diverse fish species. As such, microhabitat patches are key components of freshwater stream ecosystem heterogeneity, and a suitable patch composition in stream construction or restoration schemes will support ecologically healthy food webs.

Multiuser chirp modulation for underwater acoustic channel based on VTRM

  • Yuan, Fei;Wei, Qian;Cheng, En
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.9 no.3
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    • pp.256-265
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    • 2017
  • In this paper, an ascheme is proposed for multiuser underwater acoustic communication by using the multi-chirp rate signals. It differs from the well known TDMA (Time Division Multiple Access), FDMA (Frequency Division Multiple Access) or CDMA (Code Division Multiple Access), by assigning each users with different chirp-rate carriers instead of the time, frequency or PN code. Multi-chirp rate signals can be separated from each other by FrFT (Fractional Fourier Transform), which can be regarded as the chirp-based decomposing, and superior to the match filter in the underwater acoustic channel. VTRM (Virtual Time Reverse Mirror) is applied into the system to alleviate the ISI caused by the multipatch and make the equalization more simple. Results of computer simulations and pool experiments prove that the proposed multiuser underwater acoustic communication based on the multi-chirp rate exhibit well performance. Outfield experments carrie out in Xiamen Port show that using about 10 kHz bandwidth, four users could communicate at the same time with 425 bps with low BER and can match the UAC application.

Implementation of tractor implement ECU based on ISO11783 using IsoAgLib (IsoAgLib을 이용한 ISO11783 기반 트랙터 작업기 ECU 구현)

  • Roh, Seungku;Kim, Jayu;Tumenjargal, Enkhbaatar;Chong, Kitchong;Ham, Woonchul
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2017.04a
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    • pp.18-18
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    • 2017
  • ISO11783은 농업 산업분야 통신 프로토콜의 국제 표준으로, 농용트랙터 및 작업기 ECU 간의 통신 프로토콜을 표준화한다. 이 표준은 서로 다른 제조사의 제품 간에 호환성을 갖게 하며, 정밀 농업에 대한 핵심 기반을 제공한다. 현재 해외에서는 이미 ISO11783 기반의 AFS(Advanced Farming System)를 통한 정밀농업이 상용화되어 농가에 보급되고 있다. 이에 비해, 국내에서 이러한 표준을 따르는 농기계들은 미비한 실정이며, 향후 농업의 정밀 농업화를 통한 고부가가치 창출 및 선진국의 무역 장벽에 대비와 해외 수출 판로 개척을 위해 ISO11783 표준에 대한 R&D가 필요로 한다. 이에 IsoAgLib를 분석하고 임베디드 보드에 Porting하여 ISO11783 기반 작업기 ECU를 구현하였고, 이를 기반으로 ISO11783 기반 작업기 ECU의 구현 방법을 발표한다. IsoAgLib의 시스템 아키텍처는 계층화 되어 있어, 타겟에 의존적인 계층만 수정하여, IAR 환경에서 Cortex M3 보드에 포팅을 완료하였다. 작업기 ECU들은 자신만의 인터페이스 화면을 갖으며, 이를 Object pool이라 한다. 이것을 Virtual Terminal(VT)에 업로드 하여, VT가 해당 작업기 ECU의 사용자 인터페이스 기능을 제공하도록 한다. 이에 작업기 ECU 구현 1 단계로, 'VT-Designer'를 통하여 Object pool를 설계한다. 2 단계, 'vt2iso'를 통해서 Object pool을 IsoAgLib 상에서 사용할 수 있도록 변환한다. 3 단계, 포팅된 IsoAgLib project에 변환된 파일을 포함 시킨다. 4 단계, 작업기 ECU의 주기적인 작업 및 각 메시지 수신시 수행할 작업을 코딩한다. 5 단계, 빌드 및 타겟 보드에 업로딩 한 후, New Holland 사의 $Intelliview^{TM}$ iv display (VT)과 연결하여 동작을 확인한다. 확인 결과로 VT에 디자인한 Object pool이 표시 되며 soft key 입력 시 작업기 ECU에서 LED가 변한다. 결론적으로, 연구 결과를 바탕으로 ISO11783 기반의 작업기 ECU의 디자인 및 구현이 가능하며, 이를 통해 향후 국내의 ISO11783 기반의 작업기 ECU의 개발에 도움을 줄 수 있다.

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Measurement of the left ventricular regurgitation by gated cardiac blood pool scan: Before and after valvular replacement surgery (대동맥 및 승모판 판막폐쇄부전증에서 방사성동위원소 심혈관촬영술을 이용한 혈역류량 측정에 관한 연구)

  • Shin, Seong-Hae;Chung, June-Key;Lee, Myung-Chul;Cho, Bo-Youn;Seo, Jung-Don;Lee, Young-Woo;Koh, Chang-Soon;Suh, Kyung-Phill;Lee, Yung-Kyoon
    • The Korean Journal of Nuclear Medicine
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    • v.16 no.2
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    • pp.29-36
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    • 1982
  • Quantification of the regurgitation amount is important before and after valvular replacement surgery. Until now cardiac catheterization with cineventriculography, echocardiography have been used to measure the regurgitation amount, but also have many limitations. EKG gated cardiac blood pool scan provides a simple, non-invasive -method for quantify the regurgitation amount. By calculating the ratio of left ventricular to right ventricular stroke counts (stroke volume ratio) in gated bood pool scan, we measured the left ventricular regurgitation amount in 28 cases of valvular regurgitation and 25 cases of normal group. 1. Stroke volume ratio was higher in cases of valvular regurgitation $(2.11{\pm}0.58)$ than in cases of normal control $(1.15{\pm}0.31)$. (p<0.01). 2. Stroke volume ratio was classified by regurgitation grade using X-ray cineventriculography. In grades of mild regurgitation $(Grade\;I{\sim}II)$, stroke volume ratio was $2.02{\pm}0.29$, and in grades of severe regurgitation $(Grade\;III{\sim}IV)$, stroke volume ratio was $2.55{\pm}0.34$, so stroke volume ratio was well correlated with the grade of X-ray cineventriculography. 3. Stroke volume ratio was classfied by functional class made in New York Heart Association. In classes of mild regurgitation $(class\;I{\sim}II)$, stroke volume ratio was $2.08{\pm}0.26$, and in classes of severe regurgitation $(class\;III{\sim}IV)$, stroke volume ratio was $2.55{\pm}0.38$, Stroke volume ratio well represented the functional class. 4. After aortic and mitral valve replacement in 28 patients, the stroke volume ratio, decreased from $2.11{\pm}0.58\;to\;1.06{\pm}0.26$. Gated blood pool scan provides a noninvasive method of qnantifying valvular regurgitation and assessing the result of surgical interventions.

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Design Self-Organization Routing Protocol for supporting Data Security in Healthcare Sensor Network (헬스케어 센서 네트워크에서 데이터 보안을 지원한 자기구성 라우팅 프로토콜 설계)

  • Nam, Jin-Woo;Chung, Yeong-Jee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.517-520
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    • 2008
  • Wireless sensor network supporting healthcare environment should provide customized service in accordance with context information such as continuous location change and status information for people or movable object. In addition, we should consider data transmission guarantees a person's bio information and privacy security provided through sensor network. In this paper analyzes LEACH protocol which guarantees the dynamic self-configuration, energy efficiency through configuration of inter-node hierarchical cluster between nodes and key distribution protocol used for security for data transmission between nodes. Based on this analysis result, we suggested self-configuration routing protocol supporting node mobility which is weakness of the existing LEACH protocol and data transmission method by applying key-pool pre-distribution method whose memory consumption is low, cluster unit public key method to sensor node.

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Safety assessment of Generation III nuclear power plant buildings subjected to commercial aircraft crash Part II: Structural damage and vibrations

  • Qu, Y.G.;Wu, H.;Xu, Z.Y.;Liu, X.;Dong, Z.F.;Fang, Q.
    • Nuclear Engineering and Technology
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    • v.52 no.2
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    • pp.397-416
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    • 2020
  • Investigations of the commercial aircraft impact effect on nuclear island infrastructures have been drawing extensive attention, and this paper aims to perform the safety assessment of Generation III nuclear power plant (NPP) buildings subjected to typical commercial aircrafts crash. At present Part II, based on the verified finite element (FE) models of aircrafts Airbus A320 and A380, as well as the NPP containment and auxiliary buildings in Part I of this paper, the whole collision process is reproduced numerically by adopting the coupled missile-target interaction approach with the finite element code LS-DYNA. The impact induced damage of NPP plant under four impact locations of containment (cylinder, air intake, conical roof and PCS water tank) and two impact locations of auxiliary buildings (exterior wall and roof of spent fuel pool room) are evaluated. Furthermore, by considering the inner structures in the containment and raft foundation of NPP, the structural vibration analyses are conducted under two impact locations (middle height of cylinder, main control room in the auxiliary buildings). It indicates that, within the discussed scenarios, NPP structures can withstand the impact of both two aircrafts, while the functionality of internal equipment on higher floors will be affected to some extent under impact induced vibrations, and A380 aircraft will cause more serious structural damage and vibrations than A320 aircraft. The present work can provide helpful references to assess the safety of the structures and inner equipment of NPP plant under commercial aircraft impact.