• Title/Summary/Keyword: key exposure

Search Result 445, Processing Time 0.028 seconds

Sensitive Period of Auditory Perception and Linguistic Discrimination

  • Cha, Kyung-Whan;Jo, Hannah
    • Phonetics and Speech Sciences
    • /
    • v.6 no.1
    • /
    • pp.59-67
    • /
    • 2014
  • The purpose of this study is to scientifically examine Kuhl's (2011), originally Johnson and Newport's (1989) critical period graph, from a perspective of auditory perception and linguistic discrimination. This study utilizes two types of experiments (auditory perception and linguistic phoneme discrimination) with five different age groups (5 years, 6-8 years, 9-13 years, 15-17 years, and 20-26 years) of Korean English learners. Auditory perception is examined via ultrasonic sounds that are commonly used in the medical field. In addition, each group is measured in terms of their ability to discriminate minimal pairs in Chinese. Since almost all Korean students already have some amount of English exposure, the researchers selected phonemes in Chinese, an unexposed foreign language for all of the subject groups. The results are almost completely in accordance with Kuhl's critical period graph for auditory perception and linguistic discrimination; a sensitive age is found at 8. The results show that the auditory capability of kindergarten children is significantly better than that of other students, measured by their ability to perceive ultrasonic sounds and to distinguish ten minimal pairs in Chinese. This finding strongly implies that human auditory ability is a key factor for the sensitive period of language acquisition.

Preventing the Transmission of Tuberculosis in Health Care Settings: Administrative Control

  • Jo, Kyung-Wook
    • Tuberculosis and Respiratory Diseases
    • /
    • v.80 no.1
    • /
    • pp.21-26
    • /
    • 2017
  • It is well established that health care workers (HCWs) have a considerably higher risk of occupationally acquired tuberculosis (TB). To reduce the transmission of TB to HCWs and patients, TB infection control programs should be implemented in health care settings. The first and most important level of all protection and control programs is administrative control. Its goals are to prevent HCWs, other staff, and patients from being exposed to TB, and to reduce the transmission of infection by ensuring rapid diagnosis and treatment of affected individuals. Administrative control measures recommended by the United States Centers for Disease Control and Prevention and the World Health Organization include prompt identification of people with TB symptoms, isolation of infectious patients, control of the spread of the pathogen, and minimization of time spent in health care facilities. Another key component of measures undertaken is the baseline and serial screening for latent TB infection in HCWs who are at risk of exposure to TB. Although the interferon-gamma release assay has some advantages over the tuberculin skin test, the former has serious limitations, mostly due to its high conversion rate.

Overexpression of Protein Kinase $C{\beta}_1$ Restores Mitogenic Responses of Enterocytic Differentiated Colon Carcinoma Cells to Diacylglycerol and Basic FGF

  • Lee, Han-Soo
    • BMB Reports
    • /
    • v.30 no.3
    • /
    • pp.194-199
    • /
    • 1997
  • Previous studies have shown that the HD3 human enterocytic differentiated colon carcinoma cell lines having low $PKC{\beta}$ activity did not respond to diacylglycerol and basic FGF by growth and by activation of pp57 MAP kinase, but undifferentiated cell lines exhibiting high $PKC{\beta}$ activity did. To confirm a role of $PKC{\beta}$ in colonocyte mitogenesis, derivatives of HD3 cell line that stably overexpress a full-length of cDNA encoding the ${\beta}_1$ isoform of human PKC were generated. The abundance and activity of $PKC{\beta}$ in two of the these cell lines, PKC3 and PKC8 were much higher than those in the C1 control cell line that carries the vector lacking the $PKC{\beta}_1\;cDNA$ insert. Following exposure to diacylglycerol or basic FGF, proliferation of PKC3 and PKC8 cells increased about 50%; but this effect was not seen with the control C1 cells. Also, in contrast to the control cells, the $PKC{\beta}_1-overproducing$ cells displayed activation of pp57 MAP kinase when treated with diacylglycerol and basic FGF as undifferentiated cell lines did. These results provide direct evidence that $PKC{\beta}_1$ which plays a key role in mitogenic responses of colon carcinoma cells to diacylglycerol and basic FGF is down-regulated in enterocytic differentiation of colon cells.

  • PDF

Effects of Light on Spinach Glycolate Oxidase Gene Expression

  • Park, Yang-Seo;Jin, Yun-Hae;Kim, Young-Chang;Choi, Jung-Do;Cho, Nam-Jeong
    • BMB Reports
    • /
    • v.28 no.3
    • /
    • pp.271-274
    • /
    • 1995
  • Glycolate oxidase is one of the key enzymes in the pathway of photorespiration. In this study we investigated the effects of light on the expression of the spinach glycolate oxidase gene. Continuous exposure to white light resulted in a gradual increase in the steady-state level of glycolate oxidase mRNA within a time period of 2~24 h in both etiolated and dark-adapted green seedlings. A short white light pulse also increased the level of glycolate oxidase mRNA in etiolated seedlings. The mRNA level reached a maximum at 6~8 h after the pulse and decreased by 24 h after the pulse. The induction patterns of the glycolate oxidase gene by white light appeared similar to those of the rbcS gene, indicating that a common or coordinating regulatory system may be involved in the expression of the glycolate oxidase and rbcS genes. A red light pulse induced an increase in the amount of glycolate oxidase mRNA and this effect was reversed by a subsequent far-red light pulse, suggesting that the expression of the glycolate oxidase gene is regulated by phytochrome.

  • PDF

The Priority of Internal Control Factors for Information Systems based on Individual Characteristics (개인 특성에 따른 정보시스템 내부통제요소 중요도에 관한 연구)

  • 박종은;이우형;이명호
    • Korean Management Science Review
    • /
    • v.21 no.1
    • /
    • pp.57-76
    • /
    • 2004
  • The development of informational technology has lead to a sharp change in not only the existing way of operations and management, but the way of human life or thinking as well. Those shifts of the paradigm in information technology have also affected Individuals to the organizational structure. A series of unexpected problems was, however, accompanied by the advance in informational technology, which had broaden its own area of application. Those problems include the losses of property or data the malfunction of systems and their wastefulness would result in, continuous increases in computer crimes, reliability and efficiency of the functional process with the development of information systems, such as the processing problems of inaccurate data, economical issues, and subjects related to safety, as interruptions of privacy, which would result from lots of one's exposure to the drains of personal information. Accordingly, Auditors' roles of information systems, for now, is more important than anything else in that they are responsible for the objective assessment of relevance and effectiveness of internal control systems under the environment of information systems. The objective of the study is, so as to obtain safety of information systems: First, to provide data to line-design internal control systems after finding internal control factors to prevent and eliminate the risks of information systems. Second, to evaluate the priorities of internal control factors with their effective management being considered as the key to settle the problems of risks of information systems. Third, to discriminate what factors affect In evaluating the relative degrees of Importance of internal control factors.

Chemical cleaning effects on properties and separation efficiency of an RO membrane

  • Tu, Kha L.;Chivas, Allan R.;Nghiem, Long D.
    • Membrane and Water Treatment
    • /
    • v.6 no.2
    • /
    • pp.141-160
    • /
    • 2015
  • This study aims to investigate the impacts of chemical cleaning on the performance of a reverse osmosis membrane. Chemicals used for simulating membrane cleaning include a surfactant (sodium dodecyl sulfate, SDS), a chelating agent (ethylenediaminetetraacetic acid, EDTA), and two proprietary cleaning formulations namely MC3 and MC11. The impact of sequential exposure to multiple membrane cleaning solutions was also examined. Water permeability and the rejection of boron and sodium were investigated under various water fluxes, temperatures and feedwater pH. Changes in the membrane performance were systematically explained based on the changes in the charge density, hydrophobicity and chemical structure of the membrane surface. The experimental results show that membrane cleaning can significantly alter the hydrophobicity and water permeability of the membrane; however, its impacts on the rejections of boron and sodium are marginal. Although the presence of surfactant or chelating agent may cause decreases in the rejection, solution pH is the key factor responsible for the loss of membrane separation and changes in the surface properties. The impact of solution pH on the water permeability can be reversed by applying a subsequent cleaning with the opposite pH condition. Nevertheless, the impacts of solution pH on boron and sodium rejections are irreversible in most cases.

A study of analysis and improvement of security vulnerability in Bluetooth for data transfer (블루투스 환경에서 데이터 전송 시 보안 취약점 분석 및 개선 방안 관련 연구)

  • Baek, Jong-Kyung;Park, Jae-Pyo
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.12 no.6
    • /
    • pp.2801-2806
    • /
    • 2011
  • During data transmissions via Bluetooth networks, data to be encrypted, or plain text between the application layer and the device layer, can be hacked similar to a key-logger by the major function hooking technique of Windows Kernel Driver. In this paper, we introduce an improved protection module which provides data encryption transmission by modifying the data transmission driver of the Bluetooth device layer, and also suggest a self-protecting scheme which prevents data exposure by various hacking tools. We implement the protection module to verify the confidentiality guarantee. Our protection module which provides data encryption with minimal latency can be expected the widespread utilization in Bluetooth data transmission.

NON-INTERACTIVE IDENTITY-BASED DNF SIGNATURE SCHEME AND ITS EXTENSIONS

  • Lee, Kwang-Su;Hwang, Jung-Yeon;Lee, Dong-Hoon
    • Bulletin of the Korean Mathematical Society
    • /
    • v.46 no.4
    • /
    • pp.743-769
    • /
    • 2009
  • An ID-based DNF signature scheme is an ID-based signature scheme with an access structure which is expressed as a disjunctive normal form (DNF) with literals of signer identities. ID-based DNF signature schemes are useful to achieve not only signer-privacy but also a multi-user access control. In this paper, we formally define a notion of a (non-interactive) ID-based DNF signature and propose the first noninteractive ID-based DNF signature schemes that are secure under the computational Diffie-Hellman and subgroup decision assumptions. Our first scheme uses random oracles, and our second one is designed without random oracles. To construct the second one, we use a novel technique that converts a non-interactive witness indistinguishable proof system of encryption of one bit into a corresponding proof system of encryption of a bit-string. This technique may be of independent interest. The second scheme straightforwardly yields the first ID-based ring signature that achieves anonymity against full key exposure without random oracles. We finally present two extensions of the proposed ID-based DNF signature schemes to support multiple KGCs and different messages.

The Relationship between Workers' Safety Behaviors and Safety Climate in Chemical Industry (화학산업 작업자의 안전행동과 안전분위기의 상관관계)

  • Baek, Jong-bae;Uhm, Minyong;Kim, Ji-sun
    • Journal of the Korean Society of Safety
    • /
    • v.30 no.5
    • /
    • pp.100-107
    • /
    • 2015
  • Korea government has established and enforced countermeasures about the various policy of industrial accident prevention. Recent chemical accidents included hazardous materials. Exposure to these chemicals can cause serious environmental poisoning and various health problems. The key factor causing these major accidents may be associated with the mistake in workers' safety behaviors. Some researchers noted workers' safety behaviors may be related to workers' safety climate. In this research, a survey was conducted to explore workers' safety behaviors and safety climate in a large petrochemical company in Korea. The company processes major petrochemical materials and any spills can be hazardous and cause chemical disasters. In this study, we explored one petrochemical company to investigate three hypotheses. 593 workers were surveyed for this study. We checked association between workers' safety behavior and safety climate. The survey result shows the people who have safety climate do safe behavior.

A Study on Vulnerability Assessment to Climate Change in Regional Fisheries of Korea (국내 수산 부문의 지역별 기후변화 취약성 평가 연구)

  • Lee, Beo-Dul;Kim, Bong-Tae;Cho, Yong-Sung
    • The Journal of Fisheries Business Administration
    • /
    • v.42 no.1
    • /
    • pp.57-70
    • /
    • 2011
  • Fisheries are subject to unexpected weather condition. While some change of it may be positive for some fisheries, the current state suggests that the effects will be undesirable for many fisheries. The aim of this study is to assess the vulnerability to climate change in 11 regional fisheries of Korea using the framework of IPCC. The vulnerability assessment depends upon the interrelation of three key elements; exposure, sensitivity and adaptive capacity, which were derived from Analytical Hierarchy Process method in this study. These elements would contribute to comprehend relative importance at the regional characteristics of fisheries. We compared the vulnerability index of 11 regional fisheries so as to look for strategies and adaptation methods to the impacts of potential climate change. Jeoun-Nam, Kyeong-Nam, and Jeju are identified as the most vulnerable provinces to climate change on their fisheries because they have high level of sensitivity to predicted climate change and relatively low adaptive capacity. The relatively low vulnerability of Ulsan, Gyeonggi reflects high financial independence, well-equipped infrastructure, social capital in these regions. Understanding of vulnerability to climate change suggests future research directions. This paper will provide a guide to local policy makers and fisheries managers about vulnerability and adaptation planning to climate change.