• Title/Summary/Keyword: joint effect

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Effects of red ginseng and Baeknyeoncho complex on the arthritis improvement (홍삼·백년초 복합물이 관절염 개선에 미치는 효과)

  • Lee, Seung-Hyeon;Lee, Chang-Hyun;Kim, Hong-Jun;Kim, Young-Sik;Shin, Min-Ji;Kim, Ji-Hyun;Ma, Sang-Yong;Lee, Se-Youn;Kwon, Jin;Oh, Chan-Ho
    • Herbal Formula Science
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    • v.29 no.2
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    • pp.81-91
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    • 2021
  • Objectives : This study was conducted to evaluate the efficacy of a complex mixture of natural substances of ginseng and baeknyeoncho on the arthritic rats. Methods : In vitro experiments were conducted to ensure the stability of the complex. After setting toxicity and concentration by MTT assay, the antioxidant effect was measured through DPPH and ABTS radical scavenging activity. To confirm the anti-inflammatory effects of the complex, levels of nitric oxide (NO) and pro-inflammatory cytokines (IL-1β, TNF-α) were measured in LPS-treated macrophage cell lines (RAW264.7). We injected monosodium iodoacetate (MIA) 50 μl (60 mg/ml) into knee joints of rats to induce osteoarthritis. The rats were divided into three groups (normal (n=5), control (n=5), and OR (n=5) group). The control group consumed 2 mg/kg of physiological saline once a day for 4 weeks, and the OR group was mixed at a concentration of 416.5 mg/kg of Baengnyeoncho (O) and 208.25 mg/kg of red ginseng (R) and ingested 1 mL each 5 days a week. Results : This complex increased the DPPH and ABTS radical scavenging rate. The complex decreased NO production and pro-inflammatory cytokine production of macrophages. In the OR group, the secretion of cytokine in serum was decreased. In histopathological examination, the joint tissue of the composite showed less damage to the synovial membrane, cartilage, and fibrous tissue than the control group. Conclusions : As a result of this study, natural complexes have antioxidant, anti-inflammatory and cartilage protection effects. Therefore, we expect the complex to be effective in treating osteoarthritis.

A Fundamental Study on Shearing/Bonding Characteristics of Interface Between Rock Mass and Backfills in Mine Openings (폐광산 채움재와 암반 경계부의 전단 및 접합특성에 관한 기초 연구)

  • Kim, Byung-Ryeol;Lee, Hyeon-woo;Kim, Young-Jin;Cho, Kye-Hong;Choi, Sung-Oong
    • Tunnel and Underground Space
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    • v.31 no.6
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    • pp.623-646
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    • 2021
  • As the demand for electric power increases with acceleration of electrification at home and abroad, the needs for coal-fired electrical power plant are accordingly increased. However, these coal-fired electrical power plants induce also many environmental problems such as increase of air pollutants, increase of possibility of land contamination by reclamation of coal ash, even though these power plants have a good economical efficiency. In case of a by-product of coal-fired electrical power plants, only 70% of them are recycled and the remaining 30% of by-product are fully buried in surrounding ground. Consequently, this study deals with coal ash backfilling mechanism in abandoned mine openings for the purposes of increasing the coal ash recycling rate as well as securing the mine area stability. In order to analyze the backfill and ground reinforcement by interaction between rock mass and backfills, the copying samples of discontinuous surface with different roughnesses were produced for bond strength tests and direct shear tests. And statistical analysis was also conducted to decide the characteristics of bond and shear behavior with joint roughness and their curing day. Numerical simulations were also analyzed for examining the effect of interface behavior on ground stability.

A Study on the Improvement of the System to Reduce Damage on Ammonia Chemical Accident (암모니아 화학사고 피해를 줄이기 위한 제도개선 연구)

  • Lee, Joo Chan;Jeon, Byeong Han;Kim, Hyun Sub
    • Journal of the Society of Disaster Information
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    • v.18 no.2
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    • pp.306-313
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    • 2022
  • Purpose: The purpose of this study is suggested to improve upon current existing methods of ammonia chemical accident prevention and damage reduction. Method: Ammonia is one of the most common toxic substances that causes frequent chemical accidents. And it was selected as leakage materials according to statistics on chemical accident. Based on actual cases of chemical accidents, CARIS modeling was used to compare the damage impact range of Ammonia and HCl and Cl. Also, find out problems with the current systems. Result: As a result of find out the range of accident influence that spreads to the surroundings when an ammonia chemical accident, it was longer than the range of influence of hydrochloric acid and shorter than that of chlorine. In addition, it was found that when chemical accident by ammonia, hydrochloric acid, or chlorine, there are apartments and schools, which can have an effect. Conclusion: It is decided that it is necessary to determine whether or not chemical accident prevention management plans and statistical investigations are submitted for workplaces dealing with ammonia, and detailed guidelines and reviews are necessary. In addition, it is judged that it is necessary to establish a DB for ammonia handling plants, and it is considered that information sharing and joint inspection among related organizations should be pursued.

Treatment Methods for Functional Recovery after Total Knee Arthroplasty (슬관절 전치환술 후 기능 회복을 위한 치료법)

  • Kim, Young-mo;Joo, Yong-bum;Park, Il-young
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.2
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    • pp.117-126
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    • 2020
  • Total knee arthroplasty is performed widely in degenerative arthritis of the knee joint, and the frequency of use is increasing. Efforts should be made to achieve functional recovery, such as returning to daily life, and the recovery of strength and range of motion after surgery. The procedure should be approached from a range of perspectives, such as patient factors, surgical technique and rehabilitation. The patient's age, degree of obesity, sex, and strength of the quadriceps muscle can affect the functional recovery after surgery. In addition, the patient's mental state, such as expectation value and satisfaction, can also have an effect. For functional recovery, patient education, pain control, and strengthening of the quadriceps muscle can be performed prior to surgery. Postoperative physiotherapy, such as icing and compression, transcutaneous electrical nerve stimulation therapy, neuromuscular electrical stimulation therapy, low frequency low intensity magnetic field therapy, strengthening of quadriceps muscle, and range of motion exercise can also be applied. In recent years, hydrotherapy, which restores the strength and balance of the leg, is being performed increasingly. These treatments are not only performed shortly after surgery, but are also performed continuously. In addition, the surgeon should apply it appropriately considering the patient's condition, compliance, and social and psychological conditions.

Clinical Study of Chuna Combination Therapy for Patients with Persistent Pain and Dysfunction after Total Knee Arthroplasty (슬관절 전치환술 후 지속 통증 및 기능 장애가 있는 환자에 대한 추나병행치료 임상연구)

  • Lee, Woong-Jin;Lee, Jin-Hyun;Park, Tae-Yong;Park, Jung-Sik;Song, Yun-Kyung
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.2
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    • pp.123-138
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    • 2022
  • Objectives This study was conducted to evaluate the clinical efficacy and safety of the chuna combination treatment for patients who complain of functional impairment and pain even 3 months after total knee arthroplasty. Methods 24 patients who had 3 months of surgery and who had knee joint pain with a score of 4 or higher on the numerical rating scale (NRS) for more than a week were selected as subjects. The test group received usual care and Chuna treatment and the control group received the administration of drugs as usual care. And then the clinical efficacy and safety were compared and evaluated. Follow-up was performed 1 month after the end of treatment. Results As a result of the analysis, it was confirmed that the primary parameter Korean Western Ontario and McMaster Universities (K-WOMAC) showed statistical significance in the amount of change in visit 2-visit 10 (V2-V10) in the pain domain and in the amount of change in visit 2-follow 1 (V2-FU1) in the functional domain and total score domain. The secondary parameter (NRS, risk of fall, and range of motion) showed a tendency to decrease in the degree of discomfort, but statistical significance could not be confirmed. Conclusions Because this study did not have enough study subjects, it is difficult to use the results as confirmatory evidence. However, it was confirmed that the 4-week Chuna treatment had a significant effect and safety in patients who underwent total knee arthroplasty. Therefore, this study is meaningful as a prior research data to prepare confirmatory evidence in the future.

Development of Multi-Reservoir System Operation Rule Curves for Hydropower Maximization in the Nam Ngum River Basin of Lao PDR (라오스 남능강 유역 다중 저수지 시스템의 최적 수력발전 운영규정 곡선 개발)

  • Lee, Hyun-Jae;Jang, Woong-Chul;Lee, Il-Ju;Lee, Jin-Hee
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.6
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    • pp.803-814
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    • 2022
  • The Lao government is continuously developing hydro-power dams in addition to the existing eight power plants in the Nam Ngum River basin and is expanding the power capacity of the existing power plants to meet the expected increase in electricity demand. Accordingly, the Lao government has requested an update on the existing reservoir operating rule curve in order to run the power plants efficiently. To this end, this study reviewed the current independent operating system as well as the joint operating system in order to maximize the annual power generation produced by a power plant by using CSUDP, general-purpose dynamic programming (DP) software. The appropriate operating regulation curve forms (URC/LRC, MRC) were extracted from the DP results, and the annual power generations were simulated by inputting them as the basic operating data of the reservoir operation set of the HEC-ResSim program. By synthesizing the amount of the annual power generation simulated, the existing operation regulation curve, the operational performance, and the opinion of the field operator, the optimal reservoir operation regulation curves that maximize the annual power generation of the target power plant were developed. Results revealed that a system operating in conjunction with the reservoir produces about 2.5 % more power generation than an independent reservoir due to the synergistic effect of the connection.

An Analysis of Trends in Research Papers Related to Picture Books: Focusing on papers in domestic academic journals (그림책 관련 연구의 동향 분석 - 국내 학술지 논문을 중심으로 -)

  • Kim, Jong-Sung
    • Journal of Korean Library and Information Science Society
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    • v.53 no.2
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    • pp.189-214
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    • 2022
  • The purpose of this study is to provide an understanding of the current status of picture book-related research in Korea. For this purpose, 1,660 picture book-related research papers produced in Korea by 2021 were analyzed. The results revealed through the analysis are summarized as follows. First, research papers began to appear in the mid-1990s and began to increase significantly around 2010. Second, the journal with the most research papers was 『Journal of Children's Literature and Education』, accounting for 17.7% of the total. Third, the representative researchers who led the production of the papers are Eun-Ja Hyun and Hea-Sook Jo. Fourth, by research type, individual research papers accounted for 39% and joint research 61%. Fifth, as a result of the analysis of the research topic, the study of the contents (analysis) of picture books (33.4%), the study of the effect of picture books (29.6%), and the study of perception, reaction, and experience of picture books (18.0%) were in order. Sixth, as a result of the research method analysis, experimental studies (35.7%), content analysis (33.7%), literature studies (13.3%), and qualitative studies (9.3%) were in order. Based on the results of the analysis, the researcher suggested diversifying the research production route, expanding the trend of collaboration between universities and the field, diversifying research topics, and enhancing the validity and diversity of research methods.

The Effect on Trunk Forward Flexion Motion of Thoraco-Abdominal Breathing Pattern Correction for Life Care Promotion in Lumbar Instability People (라이프케어증진을 위한 흉·복부 호흡패턴교정이 요추부 불안정성자들의 몸통 전방 굴곡 동작에 미치는 영향)

  • Ki, Chul;Heo, Myoung
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.245-253
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    • 2020
  • This study has conducted to investigate the changes in the mobility of the three thoraco-abdominal lines(TAMs) during breathing and in the thoracic and lumbar spine mobility(TSM, LSM) during trunk forward flexion, after breathing pattern correction. The 30 subjects with lumbar instability(LI) have divided into the breathing pattern correction exercise(BPC) group of 15 subjects and the lumbar stabilization exercise(LSE) group of 15 subjects and performed each exercise for 40 minutes at one session, and a total of 18 sessions were applied for 6 weeks. As a result, The BPC group during breathing showed a significant increase in all TAMs(p<.001) and in the TSM(p<.001) than the LSE group. Besides, had a more decrease in the LSM than the LSE group(p<.001). The BPC showed high positive correlations with TAMs(rest: r=.868, forced: r=.870) and the TSM(r=.672) and had a negative correlation with the LSM(r=-.420). Based on this result of the study, the authors believe that the BPC in LI people could decrease the lumbar flexion mobility when they have motion of trunk forward flexion with promotions in the thoracic spine and rib joint mobility by improvements in relative mobility of thoraco-abdominal lines.

Flow Safety Assessment by CFD Analysis in One-Touch Insertion Type Pipe Joint for Refrigerant (CFD 해석을 이용한 냉매용 원터치 삽입식 파이프 조인트의 유동 안전성 평가)

  • Kim, Eun-young;Park, Dong-sam
    • Journal of the Society of Disaster Information
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    • v.18 no.3
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    • pp.550-559
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    • 2022
  • Purpose: Pipes are widely used as applied devices in many industrial fields such as machinery, electronics, electricity, and plants, and are also widely used in safety-related fields such as firefighting and chemistry. With the diversification of products, the importance of technology in the piping field is also increasing. In particular, when changing the existing copper pipe to stainless steel, it is necessary to evaluate safety and flow characteristics through structural analysis or flow analysis. Method: This study investigated the safety by flow analysis of the 6.35 inch socket model, which are integrated insert type connectors developed by a company, using CFD analysis technique. For CDF analysis, RAN model and LES model are used. Result: As results of the analysis, amplitude of the pressure fluctuation acting on the wall of the piping system is formed at a level of 3,780 Pa or less, which is a very small level of pressure compared with the operating pressure or design stress of the refrigerant piping. Conclusion: These results mean that the effect of vibration caused by turbulence on the structural safety of the pipe is negligible.

A Study on the Effects of Dang Dang Integrated Corrective Therapy (당당통합교정치료의 효과에 대한 연구)

  • Sung, Jin-Wook;Jang, Hong-Gyu;Cho, Won-Nyeong;Seo, Jong-Gil;Kim, Byeong-Jin;Ko, Min-Joo
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.1
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    • pp.13-26
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    • 2022
  • Purpose : The purpose of this study was to investigate the effect of Dang Dang integrated corrective therapy including myofascial release, chuna therapy, and exercise therapy on height, muscle mass, body fat, and body water in patients with body imbalance. The secondary aim was to investigate whether the percent of change in height, muscle mass, body fat, and body water varied by age group. Methods : In total, 279 patients with body imbalance between the ages of 10 and 79 were recruited at hospitals. All participants had Dang Dang integrated corrective therapy including myofascial release, chuna therapy, and exercise therapy. The patients' height, muscle mass, body fat, and body water were measured before and after Dang Dang integrated corrective therapy using InBody. Results : The height, muscle mass, and body water significantly increased after Dang Dang integrated corrective therapy in all age groups except for the 70~79 age group and body fat significantly decreased (p < .05). The age group comparison of the percent change in height, muscle mass, and body water showed significant differences (p < .05). In the post hoc test, the percent change of height in the 10~19 age group was significantly greater than in the other age groups except for the 70~79 age group. The percent change of muscle mass and body water in the 10~19 age group was significantly greater than in the 30~39 age group. Conclusion : These findings suggest that applying Dang Dang integrated corrective therapy to patients with body imbalance, excluding patients aged 70~79, may be a useful method to increase height, muscle mass, and body water and decrease body fat through spinal and joint realignment. The best results were observed in teenagers.