• 한국전문물리치료학회지
• /
• 제21권4호
• /
• pp.1-8
• /
• 2014

Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity direct current to cortical areas, thereby facilitating or inhibiting spontaneous neuronal activity. This study was designed to investigate changes in various sensory functions after tDCS. We conducted a single-center, single-blinded, randomized trial to determine the effect of a single session of tDCS with the current perception threshold (CPT) in 50 healthy volunteers. Nerve conduction studies were performed in relation to the median sensory and motor nerves on the dominant hand to discriminate peripheral nerve lesions. The subjects received anodal tDCS with 1 mA for 15 minutes under two different conditions, with 25 subjects in each groups: the conditions were as follows tDCS on the primary motor cortex (M1) and sham tDCS on M1. We recorded the parameters of the CPT a with Neurometer$^{(R)}$ at frequencies of 2000, 250, and 5 Hz in the dominant index finger to assess the tactile sense, fast pain and slow pain, respectively. In the test to measure CPT values of the M1 in the tDCS group, the values of the distal part of the distal interphalangeal joint of the second finger statistically increased in all of 2000 Hz (p=.000), 250 Hz (p=.002), and 5 Hz (p=.008). However, the values of the sham tDCS group decreased in all of 2000 Hz (p=.285), 250 Hz (p=.552), and 5 Hz (p=.062), and were not statistically significant. These results show that M1 anodal tDCS can modulate sensory perception and pain thresholds in healthy adult volunteers. The study suggests that tDCS may be a useful strategy for treating central neurogenic pain in rehabilitation medicine.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
• /
• pp.21-24
• /
• 2008

더블T 공법(DTS)의 취약점을 개선하기 위하여 개발한 와플 형상을 가지는 PC 슬래브(이하 WAS라 칭함)의 접합성능을 검증하기 위하여 역T형 보(ITB)와 접합된 실험체를 제작하고 실험을 수행하였다. 실험체는 PC 공장에서 ITB에 WAS를 걸친 후 충전재료를 채워 넣어 조립한 후 충전재료를 타설하는 방식으로 총 3개 제작하였고, 변수는 전단키의 폭과 충전재료의 종류(덧침 콘크리트, 무수축 모르타르)로 하여 동일한 조건에서 재하 실험을 수행하였고, 접합성능 실험체의 변위 및 내력을 비교하였다. 본 연구에서의 결론은 다음과 같다. 전단키 폭은 접합성능에 큰 영향을 미치지 않는 것으로 나타났다. 따라서 충전재료의 다짐이 충분한 최소한의 전단키 폭으로 설계하여도 내력에 큰 영향을 미치지 않을 것으로 사료된다. 또한 두 부재간의 접합 부분 충전재료로 덧침 콘크리트와 무수축 모르타르를 사용한 결과, 두 재료 모두 내력을 확보하고 있는 것으로 나타나 덧침 콘크리트를 사용하여 시공의 편리성을 확보하는 것이 유리할 것으로 사료된다.

• 한방재활의학과학회지
• /
• 제26권3호
• /
• pp.17-30
• /
• 2016

Objectives The purpose of this study was to find out the effects of ChondroT on arthralgia of the Collagenase-induced osteoarthritis in rats. Methods Osteoarthritis was induced into rat by injecting Collagenase in its knee joint. Rats are divided into a total of 8 groups (n=6). Normal group was not induced for osteoarthritis whereas control groups were induced for osteoarthritis by Collagenase. Positive-A (Indomethacin) was injected with Collagenase and after 8 days, 2 mg/kg of Indomethacin was medicated. Positive-B (JOINS TAB) was injected with Collagenase and after 8 days, 20 mg/kg of JOINS TAB was medicated. Experimental groups (Chondro T) at three dose levels (50, 100 and 200 mg/kg) were injected with Collagenase and after 8days they were medicated with 10 ml/kg. Indomethacin, JOINS TAB and ChondroT were medicated each substances once a day for 10 days. Thereafter, the changes in plantar withdrawal response of osteoarthritis rats by dynamic plantar aesthesiometer were observed and then RT-PCR analysis was done to investigate the expression of related proteins. Results 1. ChondroT significantly decreased withdrawal response of mechanical allodynia compared with control group in all of the experimental groups (ChondroT-A, ChondroT-B, ChondroT-C). 2. ChondroT significantly reduced Bax/Bcl-2 ratio in all of the experimental groups (ChondroT-A, ChondroT-B, ChondroT-C). 3. ChondroT significantly reduced the expression of INF-${\gamma}$ compared with control group in group ChondroT-B, ChondroT-C. Conclusions This results suggest that ChondroT may be meaningful for suppressing the pain of osteoarthritis. Further study is needed to conduct a rigorous clinical research.

• 한방재활의학과학회지
• /
• 제30권2호
• /
• pp.67-75
• /
• 2020

Objectives SJ004 is a natural herbal medicine that contains Acyranthes japonica Nakai and Eucommia ulmoides Oliver traditionally used for joint and spinal diseases. This study aimed to establish an efficient method of extracting SJ004 to standardize using the yield, high-performance liquid chromatography (HPLC), and antioxidant assay. Methods SJ004 was extracted with distilled water, 70% and 100% of ethyl alcohol (EtOH). The method validation of 20-hydroxyecdysone and pinoresinol diglucoside was determined by HPLC-photo diode array and the content of SJ004 was calculated. The antioxidant activity of each extract was compared and measured using total flavonoids, total phenolic compounds, 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and ferric reducing antioxidant power according to the standard protocol. Results The yield was highest in pure water extract and lowest in 100% EtOH. But, the content of marker compounds indicating 20-hydroxyecdysone and pinoresinol diglucoside was highest in 100% EtOH extract. In the physiological activity measurement using antioxidant activity, 100% ethanol extract was highest. The limit of detection indicating 20-hydroxyecdysone and pinoresinol diglucoside were analyzed 0.33 ㎍/mL, 0.1616 ㎍/mL, and the limit of quantification were analyzed 1.01 ㎍/mL and 0.49 ㎍/mL respectively. Conclusions The experimental results showed that the extraction conditions have a significant effect on content of marker compounds and antioxidant activity. As a result of method validation, SJ004 was standardized by 20-hydroxyecdysone and pinoresinol diglucoside.

• 한국주거학회논문집
• /
• 제18권5호
• /
• pp.113-120
• /
• 2007

The purpose of this study is an analysis about space of housing cultural center with the marketing based on experience. By changing housing market, housing cultural center is a place to give an information, added value, image of housing. Consumers who experience a housing cultural center have an effect on purchase an apartment. The image of enterprise is important to select commodities to consumers. Today, company's brand image and concept include womanish, worthy and, sensual those. Under these views, housing cultural center should have continuous culture spaces that provide various experiential chance for consumers. The methods of this study are an analysis of brand image, analysis and application of experiential elements for housing cultural center. The results of this study have five parts. First, in Sense part, there are presented the sense of sight, smell and touch include material's color, finishing material, sound and etc. Second, in Feel part, consumers feel friendly and comfortable to brand through synesthesia. And they have a liberal mind about brand. Third, in Think part, consumers can experience a brand's image as a subject of event or space. Forth, in Act part, consumer is acted to scale of a space and aim of exhibition. Finally, in Relation part, consumers can have relation each other who visit Housing cultural center. And they can joint for interchange of information, culture enjoyment. In conclusion, this study has a great value of graft marketing view on the planning of Housing cultural center.

• 조명전기설비학회논문지
• /
• 제22권1호
• /
• pp.124-131
• /
• 2008

최근 도심지의 미관을 중요시함에 따라 전력설비의 지중화가 활발히 추진되고 있다. 지중선로의 분기나 접속을 인한 저압 지중함은 주로 사람의 통행이 빈번한 보도나 이면도로에 설치되어 있으며, 지중함 내 누전이 발생할 경우 행인이 감전될 위험이 있다. 더욱이 최근 기상이변으로 인한 폭우로 도로 침수가 자주 발생하고 있으며, 이러한 경우 인체는 물에 젓은 상태이므로 감전에 치명적일 수 있다. 본 논문에서는 저압 지중함에서 발생한 국내 외 감전사고사례의 원인과 점검결과를 분석하였으며, 분석결과 국내 외 감전사고의 사고원인은 통일하나 저압 지중함의 환경조건은 다른 것으로 나타났다. 향후 분석 자료는 저압 지중함에서의 감전사고를 방지하는데 활용필 수 있으며, 저압 지중함의 설치개선을 위한 기초 자료로 이용될 수 있을 것이다.

• 한국전산구조공학회논문집
• /
• 제22권4호
• /
• pp.307-314
• /
• 2009

본 논문은 기하학적 비선형성을 가진 보존적 단일 하중 매개변수의 탄성 상태 공간구조의 탄성 분기 좌굴해석을 위한 공간프레임의 정식화, 분기경로 추적을 위한 pin-pointing 및 분기경로 전환알고리즘을 기술하고 있다. 복잡한 좌굴 후 거동특성을 파악하기 위한 본 연구의 공간프레임요소는 오일러리안 좌표계에 의한 유한회전이론으로 강체변형을 계산하였고, 굽힘효과가 고려된 보-기둥식을 적용하여 적은 개수의 요소의 사용으로도 정해를 얻을 수 있도록 하였으며, 후좌굴해석과 같은 고도의 비선형해석을 수행하기 위해 기하강성행렬의 모멘트에 대한 영향을 고려하였다. 분기좌굴에 의한 좌굴후 평형상태인 주경로와 분기경로의 pin-pointing 알고리즘으로 특이점을 계산하였으며, 고유치 및 고유모드를 이용한 본 연구의 수치알고리즘에 의해 분기경로를 추적하였다. 분기좌굴 해석예제로 평면프레임, 평면아치 및 공간돔에 대한 분기좌굴 해석을 수행하여 본문에서 제시한 수치해석법의 정확성 및 적용성을 검증한다.

• 수산경영론집
• /
• 제33권1호
• /
• pp.69-85
• /
• 2002

Reduction of fishing grounds, which was caused by the recent fisheries agreements between Korea, Japan, and China, Is Increasing the important of coastal fisheries. Korea's coastal fisheries, however, need special management measures owing to the following problems. First, there are too many fishing fleets even though fisheries resources are continuously decreasing. Despite the fact that some of the fishing vessels have been scrapped, there still remain too many vessels and especially approximately 27,000 vessels increased during 1997-1998. Second, as the condition of fisheries resources changed radically, many fishermen are fishing by methods which they were not permitted to. These fishing methods cannot be legally supported and so there is a huge gap between the system and the reality, Third, two or three licenses are given to each coastal fishing vessel because a single license cannot give sufficient income, but some of these are formally acquired. So under such circumstances, efficient management of fisheries is impossible. Fourth, absence of demarcation among regions and industries is causing frequent conflicts and there are concerns about the decreasing fisheries resources due to competitive fishing practices. Therefore, considering the above mentioned problems Korea's coastal fisheries management should be developed as the following: First, new licenses should be limited while expanding the buy-back program. The government is currently planning to limit new licenses by introducing the fixed license number system in coastal fisheries but is somewhat passive about the buy-back program. Second, fisheries management which is based on self-regulation should be established. In order to increase the effect of fisheries management, the fishermen should decide by themselves the fish and fishing methods they would be exploiting and directly regulate them. Third, it is necessary to integrate the licenses of coastal fisheries. Since coastal fisheries management through the license system has distinct limitations, it is preferable to unify risking licenses and let the fishermen decide specific matters on their own. Finally, it is necessary to establish boundaries among the regions and industries. Joint fishing areas among regions(cities and provinces) should be established and fishing in other areas should be permitted on condition of paying the required fees. On the other hand, it is also necessary to permit coastal fishing only within certain distances.

• 대한조선학회논문집
• /
• 제45권6호
• /
• pp.679-687
• /
• 2008

The fatigue life of ship structure under cyclic loading condition is made up of crack initiation and propagation stages. For a welding member in ship structure, the fatigue crack propagation life is more important than the fatigue crack initiation life. To calculate precisely the fatigue crack propagation life at the critical welding location, the knowledge of the residual stress sensitivity on the fatigue strength is necessary. In this study, thermo elastic-plastic analysis was conducted in order to examine the effect of residual stress on the fatigue crack propagation life. Also the fatigue crack propagation lives considering residual stress were calculated using fatigue crack growth code, AFGROW, on the basis of fracture mechanics. AFGROW is widely used for fatigue crack growth predictions under constant and variable amplitude loading. The reliability of AFGROW on the fatigue of ship structure was confirmed by the comparison of the estimated results with the fatigue propagation test results.

• Journal of Acupuncture Research
• /
• 제30권3호
• /
• pp.165-171
• /
• 2013

Objectives : The purpose of this study is to investigate the effect of acupuncture treatment on a patient suffering from CRPS Type 1. Methods : A 30-year-old female patient suffering from CRPS Type 1 with symptoms of intense burning pain, joint stiffness, restricted mobility, rapid hair and nail growth, allodynia, hyperalgesia and coldness of the right leg was treated with acupuncture on six acupuncture points on the leg from 13 July to 18 July of 2011. Improvement of the patient's symptoms was evaluated by Numerical Rating Scale(NRS), Digital Infrared Thermographic Image(DITI). Results : After 6 days of treatment, NRS score decreased significantly and the DITI results showed moderate improvement in temperature. Conclusions : The results suggest that acupuncture may be an effective in reducing the symptoms of CRPS. Further study is needed to evaluate the significancy of this report.