• Title/Summary/Keyword: interventional

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A Study on Radiation Exposure Dose of Operator During Interventional Radiology Procedure (방사선 중재적 시술 중 시술자의 피폭선량에 대한 연구)

  • Jeon, Mi-Eun;Lim, Cheong-Hwan;Jung, Hong-Ryang;You, In-Gyu;Hong, Dong-Hee;Kang, Byung-Sam
    • Journal of radiological science and technology
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    • v.35 no.3
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    • pp.219-226
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    • 2012
  • Interventional radiologists are not aware of the potential injury from procedures. The purpose of this study are to evaluate radiation exposure of interventional radiologist from intervention procedures and to develop guideline of the simple methods for decreasing their radiation exposure from intervention procedure. In this study, Dosimeters were used to monitor operator doses of radiation exposure in a broad range of procedures from 20 interventional radiologist during the periods of 3 months. And, we searched protection methods of each interventional radiologist. During TACE procedure, there was using 0.5 mmPb radiation protector decreased average 89.5 % of radiation exposure. Thicker radiation protector provide decreasing radiation exposure. And radiation exposure dose decreased average 47.7 % by using pulse fluoroscopic mode. Therefore, interventional radiologist should wear protective aprons, use active shielding, monitor their doses, and know how to poisoning themselves during the procedure and operate correct of the machines for minimum dose.

The Characteristic of Radiation Exposure for Radiologist with Applying Condition in Interventional Radiology in Cardiology (심장내과의 중재적 시술시 시술조건에 따른 방사선사의 방사선 노출 특성)

  • Park, Jeong-Kyu;Cho, Euy-Hyun
    • Journal of Digital Contents Society
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    • v.13 no.3
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    • pp.421-429
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    • 2012
  • Lately, the number of interventional radiology is increased by the extension of procedure in medical radiation, and radiation exposure may be appeared differently by interventional radiologists, it is caused increase of radiation dose for radiation worker, patient, and radiologists. This study has done a comparative analysis characteristic of radiation exposure for five radiologists who executed interventional cardiology for 303 patients in S university hospital of Gyeong-Buk from Nov. 1, 2011 to Jan. 31, 2011. The average exposure time of five radiologists was 697.95sec. The average of cumulative DAP(exp) for patients was $52,730mGycm^2$ and the average of total DAP for patients was $104,875.14mGycm^2$. The average of frames for image was 855.52 frames in acquired images, and the average of frames for images was 802.2 frames in exposure images. They were statistically significant differences (p<0.05). Exposure time, cumulative DAP(fluro), cumulative DAP(exp), total DAP, acquired image, and exposure image were high correlation except cumulative DAP(exp), and acquired runs in x-ray exposure characteristics of machine. Exposure time was a great influence on radiologist. It signified that the more exposure time lead to the more radiation dose for radiologist. Radiation dose is related to ability, experience, difficulty, and precision of procedures in interventional procedure. The number of angiography and exposure time is difficult to control by radiologists. Therefore, it is in need of reasonable system which was evaluated the real dose of medical teams in interventional proceedings. We think that self education and training are required to reduce radiation dose for radiologists and radiation workers.

Recent Interventional Procedures for Spinal Discogenic Pain for Life Care : Technical and Ethical Issues (라이프케어를 위한 추간판성 통증 치료의 최신중재기법 기술적 윤리적 문제들에 관하여)

  • Hong, Young-Ki
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.4
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    • pp.311-320
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    • 2019
  • Discogenic pain which develops during the degenerative process of intervertebral disc is an intractable disease of musculoskeletal system. Unlike other diseases in modern medical science, it is not clinically confirmed through objective imaging and clinicopathologic index. Moreover, current technology has been facing difficulties finding fundamental treatment. This study examined through reviewing literature whether the therapeutic rationales of interventional procedures for the discogenic pain, such as nerve block, intradiscal electrothermal therapy and nucleoplasty, are valid and whether safety reviews such as preclinical tests are carried out faithfully during the technology development process. As a result, it is presumed that there is not yet an interventional treatment for discogenic pain, whose therapeutic rationale has been objectively verified. And there are some cases of interventional treatment that have not been adequately equipped with the preclinical test steps necessary to review the safety of the procedure during the technology development process. In conclusion, since there is still no interventional treatment for discogenic pain which has clear therapeutic rationale, it is necessary to recognize that a more careful approach is needed to judge whether the procedure is performed in clinical settings. And medical ethical issues may arise for some interventional treatment that are deemed to have been carried out without a thorough review of safety.

Prohibitin Induces Apoptosis in BGC823 Gastric Cancer Cells Through the Mitochondrial Pathway

  • Zhang, Long;Ji, Qing;Ni, Zhen-Hua;Sun, Jian
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3803-3807
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    • 2012
  • Prohibitin (PHB), an evolutionarily-conserved protein, has been found to be over-expressed in gastric cancer and be closely related with tumor malignancy. In this study, to investigate the relationship between PHB expression and cell apoptosis in the BGC823 gastric cancer cell line, low and high expression PHB in BGC823 cells was accomplished using RNA interference technology and gene transfer techniques. Cell proliferation, cell cycling, apoptosis, Bax, Bcl-2 and Cyt.c protein expression and the activation of Caspase-3,9 were assessed after 48h. Over-expression of PHB gene in BGC823 cells resulted in slow cell growth, cell arrest in G2 phase, and an increased apoptosis ratio while the opposite was found for PHB under-expressing cells. In PHB over-expressing cells, the expression of Bax gene was increased, the expression of Bcl-2 was decreased, the activation level of Caspase-3, 9 was increased, but the activation level of Caspase-8 demonstrated no change. These results indicate that PHB induced apoptosis through the mitochondrial pathway.

Reference Levels for Radiation Dose in Angiography and Interventional Radiology : In the Cerebrum (혈관 조영 검사 및 중재적 방사선 시술시 방사선량에 대한 참고 기준치 : 대뇌 중심으로)

  • Han, Jae-Bok
    • The Journal of the Korea Contents Association
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    • v.11 no.3
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    • pp.302-308
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    • 2011
  • The aim of this study is to compare reference levels for radiation dose in angiography and interventional radiology. Proposed reference levels for various procedures and classification of diseases are provided by fluoroscopy time and kerma area product(KAP) rate normalizing the body habitus focusing the cerebrum. Subarachnoid hemorrhage(SAH) represents the highest KAP-rates and aneurysm represents the lowest KAP-rates. According to these types of procedures, internal carotid artery(ICA), common carotid artery(CCA), and vertebral artery(VA) show the highest KAP-rates and guglielmi detachable coil shows the lowest KAP-rates. Therefore, the present study can suggested reference levels for patient radiation dose and is expected to be further useful in the field of radiation dose education and management of angiography and interventional radiology.

Physicians' Requirement Analysis Based Design of the Master Device Mechanism for Teleoperated Interventional Robotic System (원격 중재시술용 마스터장치에 대한 의료진 요구분석 및 이를 반영한 메커니즘 설계)

  • Woo, Hyun Soo;Cho, Jang Ho;Lee, Hyuk Jin
    • Journal of Institute of Control, Robotics and Systems
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    • v.22 no.8
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    • pp.603-609
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    • 2016
  • This paper presents an optimally designed master device mechanism for teleoperated interventional robotic system. The interventional procedures using the teleoperated robotic system and the physicians' requirements are summarized. The master device should implement 5-DOF motion including 2-DOF translational motion for the entry position control, 2-DOF rotational motion for the orientation control, and 1- DOF translational motion for needle insertion. The handle assembly includes a 1-DOF translational mechanism for needle insertion and buttons for operation mode selection. The mechanisms for the 2-DOF translational motion and the 2-DOF rotational motion are designed using motors and brakes based on the various mechanisms to satisfy all the above requirements, respectively. Absolute position sensors are adopted to implement automatic initial positioning and orientation matching at the first step of needle insertion.

Clinical Role of Interventional Radiology in Abdominal Solid Organ Trauma (복부 고형 장기 외상에 대한 인터벤션의 임상적 역할)

  • Hyun Seok Jung;Chang Ho Jeon;Sang Hyun Seo
    • Journal of the Korean Society of Radiology
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    • v.84 no.4
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    • pp.824-834
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    • 2023
  • Interventional management is commonly used for traumatic injuries to the abdominal solid organs. The American Association for the Surgery of Trauma (AAST) and the World Society of Emergency Surgery (WSES) recently published guidelines for the management and treatment of liver, spleen, and kidney injuries, emphasizing the importance of interventions. Here, we discuss the characteristics of each organ and the procedure method for each organ that interventional radiologists need to know when treating trauma patients.

Comparison of Infection between Internal-External and External Percutaneous Transhepatic Biliary Drainage in Treating Patients with Malignant Obstructive Jaundice

  • Xu, Chuan;Huang, Xin-En;Wang, Shu-Xiang;Lv, Peng-Hua;Sun, Ling;Wang, Fu-An
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2543-2546
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    • 2015
  • Purpose: Percutaneous transhepatic biliary drainage (PTBD) is a form of palliative care for patients with malignant obstructive jaundice. We here compared the infection incidence between internal-external and external drainage for patients with malignant obstructive jaundice. Methods: Patients with malignant obstructive jaundice without infection before surgery receiving internal-external or external drainage from January 2008 to July 2014 were recruited. According to percutaneous transhepatic cholangiography (PTC), if the guide wire could pass through the occlusion and enter the duodenum, we recommended internal-external drainage, and external drainage biliary drainage was set up if the occlusion was not crossed. All patients with infection after procedure received a cultivation of blood and a bile bacteriological test. Results: Among 110 patients with malignant obstructive jaundice, 22 (52.4%) were diagnosed with infection after the procedure in the internal-external drainage group, whereas 19 (27.9%) patients were so affected in the external drainage group, the difference being significant (p<0.05). In 8 patients (36.3%) in the internal-external group infection was controlled, as compared to 12 (63.1%) in the external group (p< 0.05). The mortality rate for patients with infection not controlled in internal-external group in one month was 42.8%, while this rate in external group was 28.6% (p< 0.05). Conclusion: External drainage is a good choice, which could significantly reduce the chance of biliary infection caused by bacteria, and decrease the mortality rate at one month and improve the long-term prognosis.

Radiofrequency Ablation in Treating Colorectal Cancer Patients with Liver Metastases

  • Xu, Chuan;Huang, Xin-En;Lv, Peng-Hua;Wang, Shu-Xiang;Sun, Ling;Wang, Fu-An
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8559-8561
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    • 2016
  • Purpose: To evaluate efficacy of radiofrequency ablation (RFA) in treating colorectal cancer patients with liver metastases. Methods: During January 2010 to April 2012, 56 colorectal cancer patients with liver metastases underwent RFA. CT scans were obtained one month after RFA for all patients to evaluate tumor response. (CR+PR+SD)/n was used to count the disease control rates (DCR). Survival data of 1, 2 and 3 years were obtained from follow up. Results: Patients were followed for 10 to 40 months after RFA (mean time, $25{\pm}10months$). Median survival time was 27 months. The 1, 2, 3 year survival rate were 80.4%, 71.4%, 41%, 1 % respectively. 3-year survival time for patients with CR or PR after RFA was 68.8% and 4.3% respectively, the difference was statistically significant. The number of CR, PR, SD and PD in our study was 13, 23, 11 and 9 respectively. Conclusions: RFA could be an effective method for treating colorectal cancer patients with liver metastases, and prolong survival time, especially for metastatic lesions less than or equal to 3 cm. But this result should be confirmed by randomized controlled studies.