• Korean Journal of Clinical Pharmacy
• /
• v.20 no.2
• /
• pp.159-164
• /
• 2010

Radiofrequency ablation (RA) is being used to manage atrial fibrillation (AF) with patients failed at the $1^{st}$-line anti-arrhythmic medications. Patients undergoing this procedure are at increased risk of thromboembolism after ablation, and anticoagulation management surrounding the ablation remains controversial. Although no conclusive recommendations can be made, published guidelines and data support therapeutic anticoagulation with warfarin. The purpose of this study was to analyze effectiveness of current therapy and to find factors fluctuate International Normalized Ratio (INR) values in patients undergone RA followed by anticoagulation service (ACS). Retrospective review was conducted utilizing database in a hospital. Among 110 patients under warfarin around ablation between January 2006 to September 2007, 54 patients were selected and allocated into 2 groups: Group A included 47 who discontinued warfarin after ablation, while 7 in B continued the medication. Information on demographics, amount and length of warfarin dosing, INR values and measuring frequencies, and the causing factors on INR fluctuation were abstracted. Differences were analyzed using chi-squared test, Fisher's Exact test, and unpaired Student t-test. Mean amount of warfarin before and after surgery was 4.0 mg, 4.1 mg in Group A and was 5.1 mg, 4.6 mg in Group B, respectively. Average duration of warfarin doing before ablation was 73.7 days in Group A, 129.9 days in B with no significant difference (p = 0.312). The duration time of warfarin on groups after ablation lasted several months. The number of checking INRs was 4.1 and 7.6, respectively. Inter-individual variability of INR fluctuations were $2.1{\pm}0.6$ in Group A and $2.2{\pm}0.7$ in B which were not significantly different (p = 0.062). 164 cases of decreased INR were: 'omission in taking medication, stressfulness and headache, 'increased intake of high vitamin K foods', 'lifestyle change of increased physical activities', and 'increase of food-intakes'. To the contrary, 36 cases of increased INR were: 'reduce of food-intake', 'use of non-prescription drugs', 'reduction in physical activities', and 'excessive restriction on food-intake', consecutively. In conclusion, the study validated therapeutic outcomes of RA patients who we treated with standard guideline and demonstrated 9 factors of INR fluctuations in the patient. A well-trained, pharmacist-monitored anticoagulation service could reduce the risk of adverse effects and prevent complications in patients with AF around RA operation.

• Journal of Environmental Health Sciences
• /
• v.39 no.5
• /
• pp.408-417
• /
• 2013

Objectives: Phthalates are used as plasticizers in polyvinyl chloride (PVC) plastics. As phthalate plasticizers are not chemically bound to the PVC, they can leach, migrate or evaporate into indoor air and atmosphere, foodstuffs, other materials, etc. Therefore, humans are exposed through ingestion, inhalation, and dermal exposure over their entire lifetime, including during intrauterine development. In particular, university students have a great number of opportunities to contact products including phthalates during campus life (food packaging, body care products, cosmetic, lotions, aftershave, perfume etc.). The purpose of this study was to examine levels of phthalate exposure as undergraduate students begin to use pharmaceuticals and personal care products including phthalates. Methods: Phthalate metabolites, mono-ethyl phthalate (MEP), mono-n-butyl phthalate (MnBP), mono-isobutyl phthalate (MiBP), mono-2- ethylhexyl phthalate (MEHP), {(mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP}, and mono-(2-ethlyl-5-oxohexyl) phthalate (MEOHP} were examined. 80 urine samples collected from university students were analyzed using LC/MS/MS(API 4000, Applied Bioscience) with on-line enrichment and columnswitching techniques. This study was carried out at Y university located in Gyonggi Province from 2008 to 2011. Results: The detection limit of phthalate metabolites were 0.03 ng/mL for MEP, 0.11 ng/mL for MnBP, 0.08 ng/mL for MiBP, 0.93 ng/mL for MEHP, 0.19 ng/mL for MEOHP and 0.16ng/mL for MEHHP. MnBP showed the highest urinary levels (median: 31.6 ug/L, 24.8 ug/g creatinine (cr)). Concentrations were also high for MEHHP (median: 24.1 ug/L, 19.0 ug/g cr), followed by MEOHP (median: 22.8 ug/L, 17.9 ug/g cr). In individual cases, the maximum level reached up to 348 ug/L, and 291 ug/g cr, respectively. The urinary and creatinine adjusted levels of MEP were lower than those for DBP and DEHP metabolites, but were higher in 95th percentiles. As a result, the mean daily DEP intake value was 2.3 ${\mu}g/kg$ bw/day, 3.5 ${\mu}g/kg$ bw/day for DEHP and 4.9 ${\mu}g/kg$ bw/day for DBP. Conclusion: These students' phthalate exposure levels were below the international safe level set by the EU, but higher than the 2012 KFDA survey of the age group from 3 to 18.

• The Korean Journal of Applied Statistics
• /
• v.22 no.5
• /
• pp.1115-1129
• /
• 2009

Previous research has recently shown that non-cognitive factors such as attitudes toward statistics contribute positively to statistics learning, Hence, helping students develop positive attitudes toward statistics has become one of the essential goals of statistics teaching. A wide variety of instruments assessing attitudes toward statistics were developed and validated in foreign countries, but not many in Korea. The SATS-36(Survey of Attitudes Toward Statistics-36; Schau et al., 1995) has been regarded as one of the most valid measures of attitudes toward statistics. Therefore, this study was designed to validate a Korean version of Survey of Attitudes Toward Statistics(K-SATS). Instead of six factors of the original scale, a five-factor structure including interests, value, cognitive competence, difficulty, and effort was empirically supported by the Korean student sample. The results evidenced high reliability and construct validity of K-SATS. In addition, students' attitudes towards statistics differed across gender, level of statistics courses, degree programs, and major. These findings were discussed in terms of their implications for future research and statistics teaching.

• School Mathematics
• /
• v.15 no.1
• /
• pp.101-120
• /
• 2013

International comparative studies of students' performance in mathematics have shown that Korean students possess very negative attitudes toward mathematics, while they are ranked as one of the highest in the cognitive achievement of mathematics. This has prompted mathematics educators to seek for a way to improve the quality of mathematics education. In this context, this research has been conducted to investigate the learning style of Korean middle school students under the assumption that it is of essence to understand the characteristics of our students as mathematics learners. For the purpose, in-depth interview had been conducted and sixteen middle students participated in the interview. The students were chosen to represent the average group of their age-cohorts based on their performance in mathematics and their SES. The interview was designed as a semi-structured clinical interview. In the interview, the students were given mathematical tasks dealing with central themes in the domain of function. Each student was given about 30 to 50 minutes to solve the tasks. After an interviewee finished the tasks, s/he was asked to explained how s/he solved the tasks. The researchers asked additional questions to clarify the students' understanding of the mathematical themes in the tasks and to identify their strategies for learning mathematics. The analysis of the in-depth interview has primarily identified the characteristics of the students' understanding of the main themes in function and then has been extended to investigate their characteristic styles for learning mathematics. The analysis of the interview identified the learning styles of the students as 'inductive learning based on prototypical cases', 'repeated practice of exemplar mathematics problems', 'disengaged learning', and 'double standards in learning mathematics'. Based on the results of the analysis, this research presents the implications for the improvement of mathematics education.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.6
• /
• pp.2567-2574
• /
• 2011

The purpose of this study was to investigate the effects of Korean traditional dance on acculturative stress and life satisfaction in the married immigrant women. The subjects of this quasi-experimental study were two folds as one experimental group and one control group. The subjects of experimental group were randomly composed of Korean traditional Dance. Contrary to this, the subjects of control group included those who neither participated in Korean traditional dance. All statistical analyses and description methods were computed by SPSS window 14.0. The discriminant analysis was used to find changes of the acculturative stress and life satisfaction, ANCOVA. The results of this study were as followings: Frist, there was founded that Korean traditional dance program group significantly decreased their acculturative stress. Second, there was founded that Korean traditional dance program group significantly improved their life satisfaction. It is concluded that Korean traditional dance program is directly and strongly cause and effect relations with the acculturative stress and life satisfaction in the married immigrant women.

• The Korean Journal of Pain
• /
• v.30 no.3
• /
• pp.176-182
• /
• 2017

Background: Current evidence suggests that intravenous magnesium sulfate might be effective for reducing migraine pain. In a recent pilot study, we showed that intravenous caffeine citrate could reduce the severity of migraine headache. The objective of this study is to investigate the efficacy of intravenous caffeine citrate vs. magnesium sulfate for management of acute migraine headache. Methods: We conducted a prospective quasi-experimental study from January until May 2016 in two educational medical centers of Shahid Beheshti University of Medical Sciences (Shoahadaye Tajrish Hospital and Imam Hossein Hospital), Tehran, Iran. The study included patients who were referred to the emergency department and met the migraine diagnosis criteria of the International Headache Society. Patients were allocated into 2 groups receiving either 60 mg intravenous caffeine or 2 g intravenous magnesium sulfate. The pain scores, based on the visual analog scale, were recorded on admission, as well as one and two hours after receiving the drug. A Chi-Square test and student t-test were used for analysis of baseline characteristics. A Mann-Whitney U test and Wilcoxon singed rank test were used to analyze differences in the visual analogue scale (VAS) score between and within the groups respectively. Results: In total, 70 patients (35 patients in each group) with the mean age of $33.1{\pm}11.3years$ were included (64.3% female). For the Caffeine citrate group, the median pain score decreased from 9.0 (2.0) to 5.0 (4.0) after one hour and to 3.0 (4.0) after two hours. For the magnesium sulfate group, the pain score decreased from 8.0 (2.0) to 2.0 (2.0) after one hour and to 0.0 (1.0) after two hours. Both intravenous caffeine citrate and intravenous magnesium sulfate reduced pain scores significantly but the magnesium sulfate group showed more improvement than the Caffeine citrate group after one hour (P < 0.001) and after two hours (P < 0.001). Conclusions: It is likely that both intravenous caffeine and intravenous magnesium sulfate can reduce the severity of migraine headache. Moreover, intravenous magnesium sulfate at a dose of 2 g might be superior to intravenous caffeine citrate 60 mg for the short term management of migraine headache in emergency departments.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.7
• /
• pp.112-122
• /
• 2016

This study is a descriptive study designed to identify the relationships among self-leadership, positive psychological capital, and learning flow, and the mediation effect of positive psychological capital between self-leadership and learning flow. The participants for this study were 218 nursing students following a four-year curriculum in J city and the data was collected from April 1st to April 15th, 2016, and analyzed using descriptive statistics, the t-test, one way ANOVA, Pearson's correlation and multiple regression with the SPSS 22.0 Program. There were significant correlations among self-leadership, positive psychological capital, and learning flow. In the multiple regression analysis, the main factor affecting learning flow was self-leadership, which explained 44.1% of the variance in learning flow. Moreover, of 4 the components of positive psychological capital, self-efficacy and hope had a partial mediating effect between self-leadership and learning flow. Self-leadership, positive psychological capital, and learning flow relationship were positive relevant. To enhance the learning flow ability of the nursing students, it is necessary to develop a training program to increase their self-leadership and positive psychological capital.

• Journal of Environmental Science International
• /
• v.20 no.12
• /
• pp.1585-1598
• /
• 2011

Emission reduction program for in-use diesel vehicles (ERPDV) has been enacted since 2004 over the Seoul metropolitan area, and diesel emission reduction is forced to fulfill this regulation. This study was performed to evaluate the ERPDV using $PM_{10}$ concentrations of both road-side monitoring and national background network during the period of 2004-2010. In order to assess the pure road emission, we first eliminated the long range transport effect by deducting the trend of annual national background concentrations from the road-side $PM_{10}$ concentrations, and then analyzed the time series of the resultant $PM_{10}$ concentrations over Seoul metropolitan area. The annual rates of variations of road-side $PM_{10}$ with the deduction of trend of background level show -3.2, +0.4, and -2.4 ${\mu}g/m^3$/year, in Seoul, Incheon, and Gyonggi province, respectively. There are steadily decreasing trend in Seoul with all of statistic parameters such as mean, mediam, 5%ile, 10%ile, 25%ile, 75%ile, 90%ile, and 95%ile concentrations. Incheon shows some fluctuations with positive with no significant trend, and Gyonggi province shows overall decreasing but not consistent. Student-t test shows 95% significant level of ERPDV effect in Seoul, but there exists no significant level greater than 90% in both Incheon, and Kyonggi province. Total annual averaged trend over the whole Seoul metropolitan area is estimated to lie in approximately $-2.9{\mu}g/m^3$/year in this study, implying the intimate involvement of ERPDV to a large extent. This is also suggesting that the further research cost-effectiveness of ERPDV with consideration of the long range transport process would be needed over the Seoul metropolitan area.

• The Journal of the Convergence on Culture Technology
• /
• v.6 no.3
• /
• pp.293-300
• /
• 2020

This study aims to investigate the awareness and policy demands of after school care classes of mothers with elementary school children. The participants of study were 25 mothers with elementary school children in Seoul, Gyeonggi, Incheon, Gangwon. Data collection was conducted from June 23, 2017 to July 18, 2017 by focus group interview. Through the data analysis, the results of the study were analyzed as 'the reality of the after school care class that the mother sees' and 'the policy demands of the mother's after school care class'. 'The reality of the after school care class that the mother sees' is 'the overall level of after school care class is low', 'the probability of selecting the same as a lottery', 'the quality of education that varies depending on the level of the teacher', 'for the child attending the care class negative awareness'. 'Mother's policy demands for after school care classes' are presented as 'positioning as a substitute for thinking and caring', 'improvement of separation between parents' expectations', 'expansion of care recipients', 'request for resilient management'. As the conclusion of this study, first, after school care classes need to focus on the care function. Second, it is necessary to operate after school care classes by level. Third, the realistic needs of mothers should be reflected so that after school care classes can be positioned as alternatives to private education.

• The Journal of the Convergence on Culture Technology
• /
• v.6 no.3
• /
• pp.225-231
• /
• 2020

This study aims to examine the efficacy of online lectures conducted by most universities in 2020 in response to the Covid-19 crisis. Furthermore, this study analyzes students' opinions regarding online lectures, thereby assessing the possible direction that future online lectures could take. This study's results indicate that online lectures can have a positive effect on learners' reading comprehension. Also, student satisfaction with online lectures was found to be quite high. Among the reasons students cited for favoring the online format were: (1) the fun presentation of class information; (2) the diversity of subjects covered; and (3) the ease of using the Internet. Among the improvements made for enhancing online lectures were technical enhancements (such as fixing attendance check authentication errors) and stabilizing the playback of lecture videos. By way of concluding, this study claims that professors who are familiar with giving lectures in person should come to recognize that online lectures are not simply another option, but are essential for the future. As such, the academic community must focus on developing online content as a way to further higher education's development in meeting the academic demands of both the present and the future.