• Journal of the Korean GEO-environmental Society
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• v.4 no.2
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• pp.57-64
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• 2003

Marston (1913) and Spangler's (1982) theory was widely used in the analysis of the earth pressure of the narrow and long excavated ditch type backfield ground. Their theory was more clearly explained by expressing the minor principle stress arch connecting the minor principle stress link induced by interaction between the excavated wall surface and the backfilled earth. which was done by R.L. Handy(1985). Later C.G. Kellogg(1993) extended the study from vertical symmetric to incline symmetric in the backfill space type research. In the C.G. Kellogg's study, it is assumed that the resistance of wall friction on the sloping wall could be replaced by the internal friction angle in the sloping section bottom. In the study, the resistance of wall friction in the sloping section bottom, which was applied by C.G. Kellogg, would be different in magnitude with the resistance of wall friction in sloping section. The magnitude is expected to affect in the earth pressure calculation and verified by the soil test box, the C.G. Kellogg's theory, the numerical analysis and the modified C.G. Kellogg's theory considering the friction resistance to influence the incline wall.

• Journal of Korean Academy of Nursing
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• v.46 no.6
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• pp.813-823
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• 2016

Purpose: This study was done to develop and validate a measure to evaluate the Korean version of psychological insulin resistance (K-PIR) in patients with diabetes in Korea. Methods: Items were initially generated from literature reviews and interviews with 19 patients with diabetes. The content validity of the items was evaluated by experts. Participants were 424 patients with diabetes recruited through convenience sampling. A cross-sectional survey was designed for item-analysis, exploratory factor analysis with principal axis factoring, and confirmatory factor analysis. Cronbach's alpha was calculated to measure the internal consistency. Results: For the 24 items of the Korean version of psychological insulin resistance, six items were eliminated because of low correlation with the other items. Exploratory factor analysis with 18-item showed that two factors (psycho-cognitive factor and supportive factor) explained 41.8% of the variance, and the factor structure of K-PIR model had a good fit. Internal consistency of K-PIR with 18 items revealed good reliability. Conclusion: The findings show that the K-PIR is reliable for measuring the psychological resistance to insulin therapy for Korean patients with diabetes. However, further study is needed to evaluate the validation because the proportion of variation of K-PIR was low in this study.

• Journal of Korean Society of Water and Wastewater
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• v.35 no.3
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• pp.197-204
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• 2021

In MBR, extracellular polymeric substance (EPS) is known as an important factor of fouling; soluble EPS (sEPS) affects internal contamination of membrane, and bound EPS (bEPS) affects the formation of the cake layer. The production of EPS changes according to the composition of influent, which affects fouling characteristics. Therefore, in this study, the effects of the F/M ratio on the sEPS concentration, bEPS content, and fouling were evaluated. The effects of F/M ratio on the amount and composition of EPS were confirmed by setting conditions that were very low or higher than the general F/M ratio of MBR, and the fouling occurrence characteristics were evaluated by filtration resistance distribution. As a result, it was found that the sEPS increased significantly with the increase of the F/M ratio. When the substrate was depleted, bEPS content decreased because bEPS was hydrolyzed into BAP and seemed to be used as a substrate. In contrast, when the substrate is sufficient, UAP (utilization-associated products) was rapidly generated in proportion with the consumption of the substrate. UAP has a relatively higher Protein/Carbohydrate ratio (P/C ratio) than BAP, and this means, it has a higher adhesive force to the membrane surface. As a result, UAP seems like causing fouling rather than BAP (biomass-associated products). Therefore, R_f (Resistance of internal contamination) increased rapidly with the increase of UAP, and R_c (Resistance of cake layer) increased with the accumulation of bEPS in proportion, and as a result, the fouling interval was shortened. According to this study, a high F/M ratio leads to an increment in UAP generation and accumulation of bEPS, and by these UAP and bEPS, membrane fouling is promoted.

• Journal of the Korean Geosynthetics Society
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• v.21 no.3
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• pp.61-69
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• 2022

In this study, a large-scale direct shear test was performed to evaluate the shear characteristics of the pile-soil interface according to the fines content and confining pressure conditions as a reasonable evaluation method of the pullout resistance performance of pile considering the soil conditions. It was found that the shear stress was greatly generated under the conditions of high normal stress and low fines content. In addition, the maximum shear stress was found to be rather large under the conditions of the same normal stress and fines content, when pile surface had high roughness. The internal friction angle decreased at the pile-soil interface, when the fines content in the ground increased. On the other hand, the cohesion decreased under the condition of high fines content. And the internal friction angle and cohesion were large regardless of the fines content in the model ground, when the roughness of the pile surface was high.

• Journal of Life Science
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• v.15 no.6 s.73
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• pp.955-960
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• 2005

Resistance to metronidazole, a key component of therapies against Helicobacter pylori, is common in clinical isolates. Resistance generally requires inactivation of rdxA (HP0954), and sometimes also frxA (HP0642), two related nitroreductase genes. Here we studied the effect of resistance to metronidazole on fitness of the gastric pathogen H. pylori. The effect of metronidazole resistance for H. pylori in culture was assessed first by looking at colonies formed by freshly constructed mutant derivatives of H. pylori strain 26695. Mutations resulting in metronidazole resistance caused premature death of H.pylori in stationary phase, but had no significant effect on early exponential growth. The effect of nitroreductase deficiencies on fitness in vivo was tested by infecting C57BL/6 mice with 1:1 mixtures of SS1 wild type and its isogenic metronidazole resistant derivatives. Inactivation of rdxA caused an inability to colonize mice in SS1 H. pylori strain. Derivatives of a metronidazole resistant strain that survived better in stationary phase, although remaining metronidazole resistant, could again colonize mice. In conclusion, metronidazole resistance diminishes H. pylori's fitness, but their costs can be suppressed by additional mutation.

• Journal of the Korean GEO-environmental Society
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• v.22 no.12
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• pp.65-70
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• 2021

River-side Embankment collapse involves various causes. The embankment collapse due to internal erosion around embedded structures reaches up to more than 10% in Korea. Many studies are being attempted to prevent from the collapse of the embankment rooted from overtopping and instability as well as internal erosion. One of them is the study on the application of biopolymers. The application of biopolymers to soils are divided into enhancing strength, vegetation and erosion resistance. This study investigated the effect of biopolymer treated soil on erosion resistance. The main goal of the study is to obtain basic data for real-scale experiments to verify the effectiveness of biopolymer treated soil embankment including a review of the collapse pattern in the model embankment with various test conditions. The optimized experimental conditions were selected by examining the erosion patterns according to each induction path with three compaction degree of the model embankment. As a result of the experiment, the internal erosion rate in the embankment to which the biopolymer treated soil was applied is greatly reduced, and it could be concluded that it might be applied to the actual embankment. However, in this study, the conclusion was drawn only within the scaled-down model embankment. In order to practically apply the biopolymer treated soil to the embankment, the study considering the scale effect would be needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1263-1269
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• 2002

To evaluate the effect of Choakwiyeum(CKY) and Yukmijihwang-tang(YJT) water extract on the renal function and the levels of plasma aldosterone, this experiment was performed in the rabbbits. These result indicate that increase in urine volume(UV) after administration of CKY and YJT water extract is related to increase in glomerular filtration rate(GFR), free water clearance(FWC) and renal plasma f1ow(RPF) and also to decrease in plasma aldosterone concentration(PAC), which seems to be affected by renin-angiotensin-aldosterone system, and that reduced blood pressure seems to be caused by reduced peripheral resistance.

• Journal of the Korean Ceramic Society
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• v.51 no.4
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• pp.289-294
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• 2014

The stability of a solid oxide fuel cell (SOFC) stack is strongly dependent on the magnitude and profile of the internal chemical potential of the solid electrolyte. If the internal partial pressure is too high, the electrolyte can be delaminated from the electrodes. The formation of high internal pressure is attributed to a negative cell voltage, and this phenomenon can occur in a bad cell (with higher resistance) in a stack. This fact implies that the internal chemical potential plays an important role in determining the lifetime of a stack. In the present work, we fabricate planar type anode-supported cells ($25cm^2$) with a bi-layer electrolyte (with locally increased electronic conduction at the anode side) to prevent high internal pressure, and we test the fabricated cells under a negative voltage condition. The results indicate that the addition of electronic conduction in the electrolyte can effectively depress internal pressure and improve the cell stability.

• Tuberculosis and Respiratory Diseases
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• v.86 no.1
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• pp.1-13
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• 2023

Lung cancer ranks first in cancer mortality in Korea and cancer incidence in Korean men. More than half of Korean lung cancer patients undergo chemotherapy, including adjuvant therapy. Cytotoxic agents, targeted therapy, and immune checkpoint inhibitors are used in chemotherapy according to the biopsy and genetic test results. Among chemotherapy, the one that has developed rapidly is targeted therapy. The National Comprehensive Cancer Network (NCCN) guidelines have been updated recently for targeted therapy of multiple gene mutations, and targeted therapy is used not only for chemotherapy but also for adjuvant therapy. While previously targeted therapies have been developed for common genetic mutations, recently targeted therapies have been developed to overcome uncommon mutations or drug resistance that have occurred since previous targeted therapy. Therefore, this study describes recent, rapidly developing targeted therapies.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.4
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• pp.78-85
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• 2006

A person's body resistance in the waterpark, public bath and similar places is much lower than any other places due to effect of water. So low voltage may create a shock hazard for the human body in case of leakage or fault currents from lighting unit etc. We researched the related regulations which are internal standards, NEC, IEC and investigated the actual conditions for the prevention of electric shock due to lighting units in the waterpark, public bath and similar places. As a results internal standard is obscure as compared with NEC, IEC which is the limit of application and distinction of environment condition. And then internal standard's using voltage is higher than NEC, IEC in filed of water. Studies show that internal standard should be revision that raise the installation height of lighting unit, mark IP level surface of lighting unit and limit using voltage to line-to-line voltage