• Title/Summary/Keyword: internal medicine

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인진항암단의 인간 전골수성 백혈병 세포 사멸 효과 (The Effect of Paljinhangahm-dan on Human Promyelocytic Leukemia Cells(HL-60) Death)

  • 이건업;문석재;문구원;원진희;김동웅;김형균;문영호;이종범;윤준철;김흥준
    • 동의생리병리학회지
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    • 제16권3호
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    • pp.514-520
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    • 2002
  • Paljinhangahm-dan is an Oriental herbal formulation for its ability to modulate cancer cell growth and survival. This research was performed to study the anti-cancer effects of Paljinhangahm-dan water extract(PHWE) in human pro myelocytic leukemia(HL-60) cells. After HL-60 cells were routinely cultured, tetrazolium-based colorimetric(MTT) assay was performed for cytotoxicity test. To explore the mechanism of cytotoxicity. I used several measures of apoptosis to determine whether this processes was involved in PHWE-induced cell death in HL-60 cells. In addition, the experiment was practised 1 H-NMR spectroscopy to examine molecular structure of PHWE. This study suggested that PHWE control cancer cell growth through of apoptosis with less cytotoxicity in normal cells.

흉선 유암종 1예 (A Case of Thymic Carcinoid Tumor)

  • 김성민;김정미;김연수;김병철;손장원;양석철;윤호주;신동호;박성수;이정희;김완섭;박문향;최요원
    • Tuberculosis and Respiratory Diseases
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    • 제44권2호
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    • pp.425-429
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    • 1997
  • 저자들은 68세 여자에서 전종격동에 발생한 흉선 유암종 1예를 광학 및 전자현미경소견들로 확진하였기에 문헌고찰과 함께 보고하는 바이다.

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만성 활동성 B형 간염 질환 환자의 요추간판 탈출증 치험례 (Case Report of a Lumbar Disc Herniation (LDH) Patient with Chronic Active Hepatitis B)

  • 정유진;강경래;이민수;최아련;강아현;한동근;송우섭;이형철
    • 대한한방내과학회지
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    • 제37권2호
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    • pp.374-380
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    • 2016
  • Objective: Although the incidence of chronic hepatitis B has decreased around the world due to widespread national preventative control measures, mortality from the same condition can increase if the condition leads to liver cancer or liver cirrhosis. In most cases, herbal medicine does not show any statistically significant effects related to liver damage, but preconceptions do exist that herbal medicine can be toxic and cause such liver damage. To investigate this situation, this study therefore investigated a patient with hepatitis B who had combined traditional Korean medicine therapy and the use of analgesic drugs during a hospitalization period.Method: A patient with hepatitis B was given combined traditional Korean medicine therapy and the use of analgesic drugs during a hospitalization period.Results: Within 26 days, the patient was free from liver damage during the hospitalization period. She was followed up with a liver function test and was discharged after her condition improved; she also reported decreased back pain.

평형침을 포함한 한의치료로 호전된 뇌내출혈 환자의 한의치험 1례에 대한 증례보고- (A Patient with Intracerebral Hemorrhage Improved by Korean Medical Treatment including Pyung-Hyung Acupuncture: A Case Report)

  • 김해융;원서영;김정희;유주영;정은선;유호룡;설인찬;김윤식
    • 대한한방내과학회지
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    • 제42권5호
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    • pp.872-882
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    • 2021
  • Objective: This study examined the effectiveness of Pyung-Hyung acupuncture and herbal medicine for a hemiplegic patient diagnosed with intracerebral hemorrhage. Methods: The patient was treated with Pyung-Hyung acupuncture and herbal medicine for one month. Intracerebral hemorrhage symptoms were evaluated using the Korean version of the Modified Barthel Index (K-MBI), the Manual Muscle Test (MMT), and brain CT images. Results: Following Pyung-Hyung acupuncture and herbal medicine, K-MBI, MMT, and brain CT image results improved. Conclusion: This case showed that Pyung-Hyung acupuncture and herbal medicine effectively treated intracerebral hemorrhage with hemiplegia.

고립성 폐결절로 발현된 비결핵성 마이코박테리움 폐질환 1예 (Non-tuberculous Mycobacterial Lung Disease Presenting as a Solitary Pulmonary Nodule)

  • 김송이;이경종;이상훈;이상국;박병훈;정지예;손지영;윤여운;심효섭;강영애;박무석;김영삼;장준;김세규;문진욱
    • Tuberculosis and Respiratory Diseases
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    • 제69권1호
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    • pp.43-47
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    • 2010
  • We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe which was detected on the chest radiography being examed due to recurrent cough for 1 year. The computed tomography (CT) revealed a spiculated nodule containing air-bronchogram, which was suspicious of malignancy. We performed transbronchial biopsy and the pathology showed granulomatous inflammation with caseous necrosis. Under the presumptive diagnosis of pulmonary tuberculosis, we started anti-tuberculous medication including isoniazid, rifampin, ethambutol, and pyrazinamide. In one month, however, the sputum culture was positive for Mycobacterium intracellulare. The follow-up chest CT showed slight aggravation of the previous lesions. Under the final diagnosis of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule, we changed the regimen to rifampin, ethambutol, and clarithromycin. The follow-up chest CT after the completion of treatment, revealed resolution of the previous lesions.

결핵 환자에서 Rifampin에 의한 Henoch-Shönlein Purpura 1예 (A Case of Henoch-Shönlein Purpura Caused by Rifampin)

  • 김혜련;박병훈;손지영;정지예;안정련;정윤숙;임주은;정주원;문지애;변민광;김영삼;김세규;장준;이광길;박무석
    • Tuberculosis and Respiratory Diseases
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    • 제65권2호
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    • pp.116-120
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    • 2008
  • Henoch-$Sh{\ddot{o}}nlein$ 자반증은 신장, 피부, 관절, 소화기계 등의 전신을 침범하는 혈관염으로 임상적인 증상을 종합하여 진단하는 질환이며 피부나 신장에서의 조직학적 생검이 진단을 뒷받침해 주는 근거가 될 수 있다. 항결핵제 사용 중에 rifampin으로 인하여 신기능 저하, 관절 통증, 양하지 자반, 복통 등의 임상 양상이 발생하였으며 하지 피부 병변의 조직 검사로 백혈구파쇄성혈관염(leukocytoclastic vasculitis) 소견을 보여 임상적으로 Henoch-$Sh{\ddot{o}}nlein$ 자반증으로 진단하였으며 rifampin 복용 중지 후 피부 자반 소실되고, 신장 기능이 회복된 예를 문헌 고찰과 함께 보고하는 바이다.

혈관육종의 낭성 폐전이에 의한 기흉 1예 (A Case of Pneumothorax Caused by Cystic Lung Metastasis of Angiosarcoma)

  • 이찬주;최준정;전한호;정경수;박병훈;박선철;신상윤;정우영;변민광;문지애;김영삼;김세규;장준;김성규;박무석
    • Tuberculosis and Respiratory Diseases
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    • 제64권5호
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    • pp.374-378
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    • 2008
  • 혈관육종은 매우 드문 악성종양으로 고령 남자의 두피나 얼굴에 주로 발생하며, 폐로 전이되는 경우가 있다. 폐전이의 경우 객혈, 기흉 등의 호흡기계 증상을 일으킬 수 있다. 저자들은 혈관육종의 폐전이가 낭성변화를 일으켜 기흉 및 혈흉을 초래한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

침치료가 뇌졸중으로 인한 구음장애에 미치는 음향적 특성에 대한 증례보고 (Clinical Acoustic Study of Acupuncture Therapy Effects on Post-Stroke Dysarthria)

  • 이민구;박세욱;이선우;유현희;이승언;김용정;손지우;임은경;김성남;이인;문병순;윤종민
    • 대한한방내과학회지
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    • 제26권3호
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    • pp.660-669
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    • 2005
  • Objectives : The aim of this study is to find the acoustic characteristics of acupuncture therapy effects on post-stroke dysarthria. Methods : Acupuncture therapy was applied for four to six weeks by inserting needles into eight acupuncture points, CV23, CV24, bilateral 'Sheyu' and ipsilateral ST4, ST6 and contralateral LI4, ST36 on facial palsy side. All the speech samples were collected, pre-treatment and post-treatment, using Computerized Speech Lab. VOT and TD of each speech sample and vowel formant(F1&F2) were analyzed on spectrogram. Result : VOT and TD were decreased after treatment. F1 was decreased, and F2 was increased after treatment. Conclusions : This suggests that acupuncture therapy improves symptoms of post-stroke dysarthria by stimulating articulation organs such as tongue, lips, cheeks, larynx and pharynx.

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투석하지 않는 만성신질환 환자에서 cilostazol 투여 중에 발생한 복벽의 자발성 근육내 혈종 (Spontaneous abdominal intramuscular hematoma in a non-dialysis chronic kidney disease patient under cilostazol therapy)

  • 강성희;유형민;나하영;고영경;권세웅;임채호;김선웅;조영일
    • Journal of Yeungnam Medical Science
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    • 제31권2호
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    • pp.139-143
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    • 2014
  • Spontaneous intramuscular hematoma of the abdominal wall is a rare condition characterized by acute abdominal pain. It is often misdiagnosed as a surgical condition. It used to be associated with risk factors such as coughing, pregnancy, and anticoagulant therapy. Most cases of abdominal wall hematomas were rectus sheath hematomas caused by the rupture of either the superior or inferior epigastric artery, but spontaneous internal oblique hematoma was extremely rare. In this report, we present a case of spontaneous internal oblique hematoma in a 69-year-old man with non-dialysis chronic kidney disease who was taking cilostazol. The patient complained of abrupt abdominal pain with a painful palpable lateral abdominal mass while sleeping. The abdominal computed tomography showed an 8 cm-sized mass in the patient's left internal oblique muscle. The administration of cilostazol was immediately stopped, and the intramuscular hematoma of the lateral oblique muscle disappeared with conservative management.