• 한방비만학회지
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• 제7권2호
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• pp.27-37
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• 2007

Background Clinical practice guidelines (CPG) are systematically developed statements to assist practitioners and patients on healthcare decisions. They provide recommendations for the average patient, which should take into account individual clinical judgment and the patient's values and expectations. Ephedra has sympathomimetic effect and has been used for weight loss worldwide. However, its safety is controversial especially in autonomic and cardiovascular systems. Therefore, the need of appropriate CPG for ephedra prescription in obesity was advocated in Korean Traditional Medicine. Methods The committee comprised of specialists of obesity, oriental herbology, oriental cardiology, constitutional medicine. The committee collected all relevant references about adverse effect and safety of ephedra in the forms of meta-analysis, systematic review, randomized controlled trial, case-control study and observational study from international and domestic databases and paper journals. 11 English- and 5 Korean-language references were gathered and categorized by PICO (Patient, Intervention, Comparison, Outcome) method. We could not complete strength of recommendation which should be clarified according to the evidence grade estimation. Result The first version of CPG for ephedra prescription in obesity was issued by Korean Oriental Association for Study of Obesity. It includes topics of introduction, pharmacokinetics, side effects and adverse events, constitutional aspect and recommendations for dose, indication and contraindication. Conclusion There should be periodic upgrade of this CPG from now on. Although there are some drawbacks in this version of CPG, it has significance as the first CPG in Korean Traditional Medicine.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제40권3호
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• pp.103-110
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• 2014

Objectives: In this study, we assessed soft tissue asymmetry that occurred after open reduction of unilateral zygomaticomaxillary complex (ZMC) fractures. We proposed a simple method to assess soft tissue asymmetry after reduction surgery by evaluating the symmetry between the affected and the unaffected sides. The factors affecting soft tissue contour after surgery were also analyzed. Materials and Methods: Subjects included patients admitted to Wonkwang University Dental Hospital from 2008 to 2013. Cone-beam computed tomography (CBCT) images of asymmetric patients who underwent open reduction at least 3 months prior were compared with healthy patients. Results: The degree of asymmetry was measured in both the open reduction and control groups. Landmarks that showed a statistically significant difference between the two groups were zygion ($1.73{\pm}0.24mm$), bucclae ($1.08{\pm}0.26mm$), point of cheek ($2.05{\pm}0.33mm$) and frontozygomatic point ($1.30{\pm}0.31mm$). Conclusion: When compared with the normal group, asymmetry can occur in the affected side, which usually shows depression of overlying soft tissue and is statistically significantly different. Evaluation of soft tissue asymmetry with CBCT images after open reduction of ZMC fracture is useful.

• 한국도로학회논문집
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• 제7권4호
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• pp.69-77
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• 2005

줄눈 콘크리트포장에서 적정한 줄눈간격은 슬래브의 거동에 의해 발생하는 인장응력 줄눈채움재의 파손과 다웰바의 하중전달율(LTE)의 저하를 방지하여 도로포장의 장기 공용성 증가에 큰 영향을 미친다. 하지만 국내 줄눈간격은 경험적이고 획일적으로 이루어진다. 그러므로 본 연구는 국내 권역별 기후조건을 토대로 합리적인 줄눈간격 산정에 대한 방안을 제시하였다. 합리적인 줄눈간격은 초기거동에서 환경하중의 영향에 따른 건조수축과 수화열에 의해 무작위 균열 발생하지 않도록 산정하였다. 그리고 장기거동에서 줄눈폭의 과도한 움직임에 따른 LTE 저하로 인해 포장파손이 발생하지 않도록 줄눈간격을 산정하였다. 본 연구에서 산정된 줄눈간격 잠정안은 6$\sim$8m이며, 포장파손 예측 모델을 통해 줄눈간격을 8m로 증가시켜도 포장 공용성엔 큰 차이가 없었다.

• 한국통신학회논문지
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• 제34권6A호
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• pp.506-514
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• 2009

센서 네트워크를 위한 MAC 프로토콜들은 전력 소모를 최소화하기 위해 낮은 듀티 사이클(Duty Cycle)을 사용한다. 그 중에서 RMAC [4]의 경우 Pioneer(PION) 프레임을 이용하여 한 주기 내에 여러 홉을 전송한다. 본 논문에서는 HE-MAC(Hop-Extended MAC)이라는 홉 연장 프로토콜을 제안한다. HE-MAC의 데이터 전송은 기존 RMAC과는 달리 한 주기 내에 전달될 수 있는 최대 홉 수 정보가 포함된 Explorer(EXP)를 이용하여 이루어진다. EXP의 정보와 Ready-to-Receive(RTR) 상태를 이용하여 RMAC에 비해 2홉을 늘림으로써 평균 전송 지연 시간을 감소시킨다. 또한, 적응적 슬립을 통하여 불필요한 전력 소모를 최소화할 뿐만 아니라 RMAC에서 나타나는 잦은 트래픽(Traffic)으로 인한 패킷 역전 문제를 해결한다. HE-MAC의 패킷 전송 지연시간을 수학적으로 분석하였으며, ns-2를 이용한 모의실험을 통해 성능평가를 하였다. 300개의 노드가 배치된 랜덤 토폴로지에서 HE-MAC은 RMAC에 비해 전력 소모량과 평균 전승 지연 시간을 14%, 20%만큼 감소시킨다.

• Journal of the Korean Data and Information Science Society
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• 제21권3호
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• pp.407-417
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• 2010

신BIS협약에서는 자본적정성 규제에 있어서 자율성 확대를 위해 내부등급시스템을 허용하였고, 이에 따라 시스템의 적합성 검증의 중요성을 더욱 강조하게 되었다. 적합성검증은 양적 질적 검증으로 나뉘며 이 때 양적 검증은 변별력, 안정성, 등급의 계량화로 구별된다. 본 논문에서는 양적 검증의 등급의 계량화 중 신용등급 변화 검정기법에 대하여 연구하려고 한다. 등급의 계량화 검정은 등급별로 추정된 부도율과 실제 부도율과의 차이를 검정하는 방법으로 한 시점에 대한 검정으로 이항검정과 카이제곱검정, Brier score, 신호등 검정이 있고, 여러 시점의 정확성을 검증하는 방법으로 정규성 검정, 확장된 신호등 검정이 있다. 신용평가시스템의 정확성을 높이고, 현실 상황에 반영이 가능하려면 상관관계를 고려하지 않을 수 없다. 본 논문에서는 부도상관관계를 고려한 확장된 신호등 검정을 제안하고자 한다.

• 한국전문물리치료학회지
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• 제20권3호
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• pp.81-88
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• 2013

Active straight-leg raise (ASLR) is a physical evaluation procedure to test lumbar spine stability. Several previous studies have reported various methods to control the activation of abdominal muscles during ASLR. We investigated the effects of three different hip positions in frontal plane on abdominal muscles to increase or decrease the difficulty level of lumbar spine stability exercise during ASLR in pain free subjects. Eleven young and healthy subjects voluntarily participated in this study (6 men, 5 women; mean age=$24.0{\pm}1.2$ years, height=$160.0{\pm}7.3cm$, weight=$55.0{\pm}10.6kg$, body mass index=$21.5{\pm}2.3kg/m^2$). The subjects had three trials on each ASLR with hip $10^{\circ}$ adduction, neutral hip, and hip $30^{\circ}$ abduction. Separate repeated-measures analysis of variance (ANOVA) and the post hoc Bonferroni tests (with ${\alpha}$=.05/3=.017) were performed for each muscle among the three different hip positions in frontal plane (ASLR with hip $10^{\circ}$ adduction, neutral hip, and hip $30^{\circ}$ abduction). The ipsilateral external oblique (EO), contralateral EO, ipsilateral internal oblique/transverse abdominis (IO/TrA), and contralateral IO/TrA were significantly greater in ASLR with hip $30^{\circ}$ abduction compared with ASLR with hip $10^{\circ}$ adduction. Also, the ipsilateral EO, contralateral EO, and ipsilateral IO/TrA were significantly greater in ASLR with hip $30^{\circ}$ abduction compared with ASLR with neutral hip. These results suggest that ASLR with hip $30^{\circ}$ abduction and neutral would be useful method to strengthen the EO and IO/TrA. And, ASLR with hip $10^{\circ}$ adduction would be effective in early stages of lumbar stabilization program due to low activation of EO and IO/TrA during maintaining of ASLR position with low load.

• 대한의생명과학회지
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• 제10권4호
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• pp.515-521
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• 2004

To measure regional cerebral blood volume (rCBV) with perfusion MR imaging of cerebral fat embolism by neutral fat and free fatty acids in cats. Triolein (group 1, n=15), oleic acid (group 2, n=9) and linoleic acid (group 3, n=11) were infused into unilateral internal carotid artery using microcatheter through the transfemoral approach. PVA particle was used as a non-fat embolic material in a control group (group 4, n=9). Perfusion-weighted MR image was obtained at 30 minutes and 2 hours postembolization, based on T2-and diffusion-weighted images. The data of lesion and contralateral normal area were transferred to personal computer, time-to-signal intensity curve was drawn and trans for used to △R2/sup */ curve in regular order. The process in the personal computer was done by using the author's developmental image processing program and interactive data language (IDL) softwares. Statistical significance was approved by paired t-test and ANOVA. rCBV of the lesion was decreased comparing to the normal area in all groups. The ratios of rCBV were as follows (group No, at 30 minutes, at 2 hours); group 1,32％, 51％; group 2, 30％, 44％; group 3, 39％, 61％; group 4, 21％, 36％. rCBVs of 2 hours was significantly increased compared to those of 30 minutes in all groups (P<0.005). rCBV was decreased at 30 minutes in cerebral fat embolism and recovered a little, but significantly at 2 hours. Perfusion-weighted images was useful method in offering hemodynamic information in cerebral fat embolism.

• 한국식품영양학회지
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• 제32권6호
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• pp.745-752
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• 2019

The purpose of this study was to determine the difference in vitamin B₆ content according to the varieties, regions, and harvest times of vegetables and fruits in Korea using high performance liquid chromatography. We verified the accuracy of the analytical method with standard reference material 1849a and achieved reliability for internal analysis quality control with a mixture of cereal, whole wheat, and flour. As a result of the analysis, vitamin B₆ contents (㎍/100 g) were 6.9~86.5 in peppers, 5.1~17.2 in paprika, 4.4~5.0 in strawberries, 4.0~52.9 in tomatoes, 7.7~7.8 in Chinese cabbage, 17.3~23.3 in radishes, 13.4~37.6 in apples, 2.3~12.7 in peaches, and 3.7~12.7 in grapes. In general, the difference in vitamin B₆ content showed by varieties, harvest times, and regions. Peppers showed the most difference as 79.6 ㎍/100 g among the varieties, and apples showed a difference as 22.8 ㎍/100 g by regions. According to the harvest times in grape 'Mihwang', there was a difference of 7.5 ㎍/100 g. We will collect an amount of nutritional data on various food materials, and continue to build a reliable and integrated nutritional database. And then the database will be used in the 10th revision of the Korean Food Composition Table.

• 한방안이비인후피부과학회지
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• 제29권3호
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• pp.14-26
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• 2016

Objectives : This study was performed to investigate the protective effects and mechanisms of Salvia miltiorrhizae Radix extract (SME) on endotoxin shock.Methods : We used two models; LPS-induced sepsis model for in vivo model, and murine peritoneal macrophages responses for in vitro. SME was administrated orally to mice. After 1 hr, LPS was injected intraperitoneally. Survival rate was checked each time per 12 hr for 5 days. Mice were sacrificed 3 hr after LPS injection, then blood samples and organs were harvested. Cytokines secretion was measured by ELISA. Organs tissues were observed with microscope. Murine peritoneal macrophages were cultured for 1 hr either in a medium alone or in a medium that contained SME, as indicated. Then, the cells were treated with LPS for 24 hr. mRNA levels of cytokines were measured by real-time RT-PCR. Cytokine levels in the supernatants were measured by ELISA. The amount of nitrite was measured by using the Griess method to evaluate NO production. The cell lysates were analysed by Western blotting using antibodies for iNOS and β-actin was used as an internal control to monitor equal protein loading.Results : SME improverd the survival rate of mice model. SME inhibited the secretion of inflammatory cytokines and organs damages on Endotoxin Shock model. SME suppressed cytokine expression, cytokine secretion,NO production, iNOS expression in LPS-induced murine peritoneal macrophages.Conclusions : The results suggest that SME has protective effects on endotoxin shock through suppression of inflammatory cytokines, organ damages, NO production and so on.

• 성인간호학회지
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• 제14권3호
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• pp.348-358
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• 2002

Purpose: The purpose of this study was to identify the factors influencing regular exercise of the elderly in discriminating regular exercise and non - regular exercise groups. Method: The subjects of this study were 167 elderly over the age of 60, living in a rural city in Korea. The data was collected by interview and self report questionnaire in 1999. The Cronbach 's alpha of scales used this study were .66 ~.97. Result: 1. There were significant differences in doing regular exercise between the perceived importance of the health(p=021), the perceived health status(p=.050), the perceived need of the exercise(p=000), the perceived importance of the exercise(p=.000), the intent of participation in the exercise program(p=.000), IADL score(p=.022), the perceived benefits of exercise (p=.000), the emotion of exercise(p=.000), HPLP(p=.000), the self efficacy(p=.001), the perceived benefits of health promoting behaviors(p= .011), the perceived barriers of the health promoting behaviors(p=.002), and the Internal locus of control(p=.021) of the elderly. 2. Variables which showed significance for discriminating regular exercise of the elderly in this study were the perceived need of the exercise(p=.000) and the perceived benefits of the exercise(p=.000). By using the combination of these variables, the possibility of proper prediction for predicting regular exercise group was 84.8 %, non - regular exercise group was 93.9%, and total Hit ratio was 89.4%. Conclusion: To improve exercise behavior in older adults, health care providers should focus of developing interventions to strengthen the perceived benefits, the perceived needs of the exercise.