• 제목/요약/키워드: interface treatment

Search Result 904, Processing Time 0.029 seconds

Adjunctive Therapy of Pimecrolimus for Treatment of Facial Discoid Lupus Erythematosus in a Dog

  • Yeonhoo Jung;Moonseok Jang;Rahye Kang;Wanghui Lee;Seongjun Park
    • Journal of Veterinary Clinics
    • /
    • v.41 no.1
    • /
    • pp.49-53
    • /
    • 2024
  • A two-year-old, spayed female, 22.5 kg Pungsan was referred with chronic crusts and erosion on the nose. A referring veterinarian prescribed an anti-inflammatory dose (0.5-1 mg/kg/day) of oral glucocorticoids for 5 months, but skin lesions showed no meaningful improvement. A dermatological evaluation revealed a crust, depigmentation, erosion, and erythematous lesion over the nasal planum with a loss of the normal cobblestone texture. Also, firm and multifocal plaques over the thigh, groin, axilla, and dorsum were detected. A cytology examination on the nose, thigh, groin, axilla, and dorsum revealed moderate neutrophilic inflammation and bacterial infection. Abdominal radiography and ultrasonography revealed subcutaneous calcified materials along the thigh, groin, axilla, and dorsum. Calcinosis cutis was suspected because of the adverse effect of previous prolonged corticosteroid therapy. A histopathology examination of the nose lesion revealed moderate to severe degenerative or apoptotic changes of the basal layer and lymphoplasmacytic interface dermatitis. Facial discoid lupus erythematosus (FDLE) was diagnosed based on the history and the clinical, cytological, and histopathological results. Minocycline (7 mg/kg PO q 12 h) and niacinamide (500 mg/dog PO q 12 h) were prescribed as initial treatment. Glucocorticoids were not administered due to the presence of calcinosis cutis induced by previous corticosteroid treatment. After 6 weeks of treatment, the clinical signs on the nose were mildly improved. At this time, topical 1% pimecrolimus cream (twice daily) was initiated, while minocycline and niacinamide were continued at the same dose. The nasal planum markedly improved after 6 weeks of additional treatment, hence minocycline and niacinamide were prescribed for an additional 2 weeks and stopped, and the patient was continued solely on topical pimecrolimus. The dog's skin lesion has been maintained in clinical remission with topical 1% pimecrolimus twice daily for more than 5 months.

Assessment of Bond Characteristics between New and Old Concrete in Various Mixtures and Joint Conditions (배합 및 접합면 처리에 따른 신·구 콘크리트의 부착특성 평가)

  • Cho, Byeong-Du;Kim, Sang-Hyun;Jeon, Se-Jin
    • Journal of the Korea Concrete Institute
    • /
    • v.26 no.4
    • /
    • pp.507-515
    • /
    • 2014
  • Although the construction joints of a concrete structure are properly treated with some measures, leakage has frequently occurred. A series of tests on the bond characteristics between new and old concrete were carried out in this study, assuming that the leakage at the construction joints has certain relationship with the bond of concrete. To assess the bond characteristics under various conditions, a number of specimens were made that have an interface between new and old concrete and bond strength, flexural strength and splitting tensile strength were measured. Main test variables are type and amount of mineral admixtures, treatment method of the interface and type of waterstops. In addition, the effects of placing interval between the concrete and of the age of the strength tests were investigated. The test results showed a slightly increased bond strength when applying mineral admixtures, which can be attributed to the interface filled with the calcium silicate hydrate that is formed by pozzolanic reaction. On the other hand, the bond strength was higher when the interface was treated rough and dry, and the roughness of a waterstop affected the bond capacity of the waterstop. Also, an assessment is required that considers the type of strength test because the bond strength varied according to the test methods.

Oxygen Plasma Effect on AlGaN/GaN HEMTs Structure Grown on Si Substrate

  • Seo, Dong Hyeok;Kang, Sung Min;Lee, Dong Wha;Ahn, Du Jin;Park, Hee Bin;Ahn, Youn Jun;Kim, Min Soo;Kim, Yu Kyeong;Lee, Ho Jae;Song, Dong Hun;Kim, Jae Hee;Bae, Jin Su;Cho, Hoon Young
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2013.02a
    • /
    • pp.420-420
    • /
    • 2013
  • We investigated oxygen plasma effect on defect states near the interface of AlGaN/GaN High Electron Mobility Transistor (HEMT) structure grown on a silicon substrate. After the plasma treatment, electrical properties were evaluated using a frequency dependant Capacitance-Voltage (C-V) and a temperature dependant C-V measurements, and a deep level transient spectroscopy (DLTS) method to study the change of defect densities. In the depth profile resulted from the temperature dependant C-V, a sudden decrease in the carrier concentration for two-dimensional electron gas (2DEG) nearby 250 K was observed. In C-V measurement, the interface states were improved in case of the oxygen-plasma treated samples, whereas the interface was degraded in case of the nitrogen-plasma treated sample. In the DLTS measurement, it was observed the two kinds of defects well known in AlGaN/GaN structure grown on sapphire substrate, which have the activation energies of 0.15 eV, 0.25 eV below the conduction band. We speculate that this defect state in AlGaN/GaN on the silicon substrate is caused from the decrease in 2DEG's carrier concentrations. We compared the various DLTS signals with filling pulse times to identify the characteristics of the newly found defect. In the filling pulse time range under the 80 us, the activation energies changed as the potential barrier model. On the other hand, in the filling pulse time range above the 80 us, the activation energies changed as the extended potential model. Therefore, we suggest that the found defect in the AlGaN/GaN/Si structure could be the extended defect related with AlGa/N/GaN interface states.

  • PDF

Effects of sulfur treatments on metal/InP schottky contact and $Si_3$$N_4$/InP interfaces (황처리가 금속/InP Schootky 접촉과 $Si_3$$N_4$/InP 계면들에 미치는 영향)

  • Her, J.;Lim, H.;Kim, C.H.;Han, I.K.;Lee, J.I.;Kang, K.N.
    • Journal of the Korean Institute of Telematics and Electronics A
    • /
    • v.31A no.12
    • /
    • pp.56-63
    • /
    • 1994
  • The effects of sulfur treatments on the barrier heithts of Schottky contacts and the interface-state density of metal-insulator-semiconductor (MIS) capacitors on InP have been investigated. Schottky contacts were formed by the evaporation of Al, Au, and Pt on n-InP substrate before and after (NH$_{4}$)$_{2}$S$_{x}$ treatments, respectively. The barrier height of InP Schottky contacts was measured by their current-voltage (I-V) and capacitance-voltage (C_V) characteristics. We observed that the barrier heights of Schottky contacks on bare InP were 0.35~0.45 eV nearly independent of the metal work function, which is known to be due to the surface Fermi level pinning. In the case of sulfur-treated Au/InP ar Pt/InP Schottky diodes, However, the barrier heights were not only increased above 0.7 eV but also highly dependent on the metal work function. We have also investigated effects of (NH$_{4}$)$_{2}$S$_{x}$ treatments on the distribution of interface states in Si$_{3}$N$_{4}$InP MIS diodes where Si$_{3}$N$_{4}$ was provided by plasma enhanced chemical vapor deposition (PECVD). The typical value of interface-state density extracted feom 1 MHz C-V curve of sulfur-treated SiN$_{x}$/InP MIS diodes was found to be the order of 5${\times}10^{10}cm^{2}eV^{1}$. This value is much lower than that of MiS diodes made on bare InP surface. It is certain, therefore, that the (NH$_{4}$)$_{2}$S$_{x}$ treatment is a very powerful tool to enhance the barrier heights of Au/n-InP and Pt/n-InP Schottky contacts and to reduce the density of interface states in SiN$_{x}$/InP MIS diode.

  • PDF

Evaluation of tissue ingrowth and reaction of a porous polyethylene block as an onlay bone graft in rabbit posterior mandible

  • Sosakul, Teerapan;Tuchpramuk, Pongsatorn;Suvannapruk, Waraporn;Srion, Autcharaporn;Rungroungdouyboon, Bunyong;Suwanprateeb, Jintamai
    • Journal of Periodontal and Implant Science
    • /
    • v.50 no.2
    • /
    • pp.106-120
    • /
    • 2020
  • Purpose: A new form of porous polyethylene, characterized by higher porosity and pore interconnectivity, was developed for use as a tissue-integrated implant. This study evaluated the effectiveness of porous polyethylene blocks used as an onlay bone graft in rabbit mandible in terms of tissue reaction, bone ingrowth, fibrovascularization, and graft-bone interfacial integrity. Methods: Twelve New Zealand white rabbits were randomized into 3 treatment groups according to the study period (4, 12, or 24 weeks). Cylindrical specimens measuring 5 mm in diameter and 4.5 mm in thickness were placed directly on the body of the mandible without bone bed decortication, fixed in place with a titanium screw, and covered with a collagen membrane. Histologic and histomorphometric analyses were done using hematoxylin and eosin-stained bone slices. Interfacial shear strength was tested to quantify graft-bone interfacial integrity. Results: The porous polyethylene graft was observed to integrate with the mandibular bone and exhibited tissue-bridge connections. At all postoperative time points, it was noted that the host tissues had grown deep into the pores of the porous polyethylene in the direction from the interface to the center of the graft. Both fibrovascular tissue and bone were found within the pores, but most bone ingrowth was observed at the graft-mandibular bone interface. Bone ingrowth depth and interfacial shear strength were in the range of 2.76-3.89 mm and 1.11-1.43 MPa, respectively. No significant differences among post-implantation time points were found for tissue ingrowth percentage and interfacial shear strength (P>0.05). Conclusions: Within the limits of the study, the present study revealed that the new porous polyethylene did not provoke any adverse systemic reactions. The material promoted fibrovascularization and displayed osteoconductive and osteogenic properties within and outside the contact interface. Stable interfacial integration between the graft and bone also took place.

Microstructural Characterization of Clad Interface in Welds of Ni-Cr-Mo High Strength Low Alloy Steel (Ni-Cr-Mo계 고강도 저합금강 용접클래드 계면의 미세조직 특성 평가)

  • Kim, Hong-Eun;Lee, Ki-Hyoung;Kim, Min-Chul;Lee, Ho-Jin;Kim, Keong-Ho;Lee, Chang-Hee
    • Korean Journal of Metals and Materials
    • /
    • v.49 no.8
    • /
    • pp.628-634
    • /
    • 2011
  • SA508 Gr.4N Ni-Cr-Mo low alloy steel, in which Ni and Cr contents are higher than in commercial SA508 Gr.3 Mn-Mo-Ni low alloy steels, may be a candidate reactor pressure vessel (RPV) material with higher strength and toughness from its tempered martensitic microstructure. The inner surface of the RPV is weld-cladded with stainless steels to prevent corrosion. The goal of this study is to evaluate the microstructural properties of the clad interface between Ni-Cr-Mo low alloy steel and stainless weldment, and the effects of post weld heat treatment (PWHT) on the properties. The properties of the clad interface were compared with those of commercial Mn-Mo-Ni low alloy steel. Multi-layer welding of model alloys with ER308L and ER309L stainless steel by the SAW method was performed, and then PWHT was conducted at $610^{\circ}C$ for 30 h. The microstructural changes of the clad interface were analyzed using OM, SEM and TEM, and micro-Vickers hardness tests were performed. Before PWHT, the heat affected zone (HAZ) showed higher hardness than base and weld metals due to formation of martensite after welding in both steels. In addition, the hardness of the HAZ in Ni-Cr-Mo low alloy steel was higher than that in Mn-Mo-Ni low alloy steel due to a comparatively high martensite fraction. The hardness of the HAZ decreased after PWHT in both steels, but the dark region was formed near the fusion line in which the hardness was locally high. In the case of Mn-Mo-Ni low alloy steel, formation of fine Cr-carbides in the weld region near the fusion line by diffusion of C from the base metal resulted in locally high hardness in the dark region. However, the precipitates of the region in the Ni-Cr-Mo low alloy steel were similar to that in the base metal, and the hardness in the region was not greatly different from that in the base metal.

Studies on the Stabilization of Rayon Fabrics: 3. Effects of Long-Term Isothermal Stabilization at Low Temperatures and Chemical Pre-treatment (레이온직물의 안정화에 관한 연구: 3. 저온 장시간 등온 안정화 및 화학전처리 영향)

  • Cho, Chae Wook;Cho, Donghwan;Park, Jong Kyoo;Lee, Jae Yeol
    • Journal of Adhesion and Interface
    • /
    • v.11 no.1
    • /
    • pp.15-25
    • /
    • 2010
  • In the present study, isothermal stabilization processes for rayon fabrics were performed at two relatively low temperatures $180^{\circ}C$ and $200^{\circ}C$ for a long period of time. The results of weight loss, dimensional shrinkage, X-ray diffraction and scanning electron microscopic observations studied with the rayon fabrics before and after the isothermal stabilization indicated that the chemical and physical changes of rayon precursor fibers proceeded continuously and slowly at the stabilization temperature below $200^{\circ}C$. And the pre-treatment with four different chemical compounds done prior to stabilization process influenced differently the characteristics of rayon fabrics. As a result, it was noticed that under the given stabilization conditions, $H_3PO_4$ and $Na_3PO_4$ played a role in catalyzing the stabilization reaction of rayon fabric whereas $NH_4Cl$ and $ZnCl_2$ played a role in delaying or retarding the reaction. $H_3PO_4$ showed the lowest percent weight loss of the fabric in the second stabilization conducted at $350^{\circ}C$. It was considered that phosphoric acid, which has a function of flame retardant, contributed to retarding somewhat the subsequent reaction even in the second stabilization step.

Measurements of Lattice Strain in MOCVD-GaN Thin Film Grown on a Sapphire Substrate Treated by Reactive Ion Beam (활성화 이온빔 처리된 Sapphire기판 위에 성장시킨 MOCVD-GaN 박막의 격자변형량 측정)

  • Kim, Hyun-Jung;Kim, Gyeung-Ho
    • Applied Microscopy
    • /
    • v.30 no.4
    • /
    • pp.337-345
    • /
    • 2000
  • Introduction of the buffer layer and the nitridation of a sapphire substrate were one of the most general methods employed for the reduction of lattice defects in GaN thin films Brown on sapphire by MOCVD. In an effort to improve the initial nucleation and growth condition of the GaN, reactive ion beam (RIB) of nitrogen treatment of the sapphire surface has been attempted. The 10 nm thick, amorphous $AlO_xN_y$ layer was formed by RIB and was partially crystallized alter the main growth of GaN at high temperature, leaving isolated amorphous regions at the interface. The beneficial effect of amorphous layer at interface in relieving the thermal stress between substrate and GaN film was examined by measuring the lattice strain value of the GaN film grown with and without the RIB treatment. Higher order Laue zone pattern (HOLZ) of $[\bar{2}201]$ zone axis was compared with simulated patterns and lattice strain was estimated It was confirmed that the great reduction of thermal strain was achieved by RIB process and the amount of thermal stress was 6 times higher in the GaN film grown by conventional method without the RIB treatment.

  • PDF

EFFECT OF CONTAMINANTS ON THE PUTTY-WASH BOND STRENGTH IN TWO-STEP RELINE TECHNIQUE USING VINYL POLYSILOXANE IMPRESSION MATERIALS (Vinyl Polysiloxane 인상재를 이용한 이회 인상법에서 contaminants가 putty-wash 결합력에 미치는 영향)

  • Kim, Mu-Hyon;Jeong, Chang-Mo;Jeon, Young-Chan;Hwang, Hie-Seong
    • The Journal of Korean Academy of Prosthodontics
    • /
    • v.34 no.2
    • /
    • pp.266-276
    • /
    • 1996
  • Numerous factors are known to affect the accuracy of elastomeric impression materials. Factor often overlooked is the quality of the bond between putty and wash during corrective reline impression technique. The putty-wash bond strength must be strong enough to over-come the local stress at putty-wash interface. It is not always possible to avoid saliva contamination in making corrective wash impres-sion. And putty preliminary impression material con be used as a template for provisional restoration. Human saliva and the residual monomer of autopolymerizing acrylic resin are thought to affect the bond strength and the failure type. This study examined the effect of contaminants like human saliva, and residual resin monomer on the putty-wash bond strength and the effectiveness of treatment. 1. Of the tested three brands of Vinyl Polysiloxane impession meterial, Express Exhibited the greatest bond strength followed by Eamix and Perfect showed the lowest putty-wah bond strength. 2. Coating the putty substrates with human saliva did not produce decreased failure load in all the breands of Vinyl Polysiloxane impression meterail. 3. Of the three brands of VPS impression material that were exposed to methhylmethacry-late resin(Jet), only the putty-wash bond strength of the Perfect group diminished signifi-cantly. Moreover, all the specimens from group C of Perfect exhibited adhesive failure. 4. Exposing the substrates to ethylmethacrylate resin(SNAP. diminished the putty-wash bond strength significantly. With Perfect and Examix, failure occurred cohesively through the light-body, whereas with Express, failure occurred adhesive-cohesively. 5. Removing approximately 1mm thickness of the contaminated putty interface was the most effective treatment in countering the undesirable effect caused by residual resin monomer. The putty-wash bond strength of the groups that were treated with 1mm even putty reduction was not significantly different from those of control groups. With Perfect and Examix, cleaning the specimens with gauze soaked in 70% isopropyl alcohol increased the putty-wash bond strength, but was not as effective as 1mm even reduction of contaminated putty substrates. With Express, 70% isoproryl alcohol treatment exhibi0ted comparable putty-wash bond strength to that of control group.

  • PDF

Study on the Development and Property of Epoxy Putty with Excellent Low Shrinkage and Cutting Force Using Mercaptan Type and Diamine Type (Mercaptan계와 Diamine계를 이용한 저수축·절삭력이 우수한 Epoxy Putty의 개발 및 물성에 관한 연구)

  • Oh, Seung-Jun;Wi, Koang-Chul
    • Journal of Adhesion and Interface
    • /
    • v.16 no.4
    • /
    • pp.137-145
    • /
    • 2015
  • This study aimed to develop epoxy putty as a multi-purpose connection and restoration material that can be used for material-specific restoration work such as metal, wood, ceramics, earthenware and stone artifacts by replacing synthetic resins currently being used for preservation treatment of cultural assets. Existing synthetic resins have the issue of cutting force resulting from high strength, deflection resulting from long hardening time, contaminating the surface of artifacts through staining on tools or gloves and need for re-treatment resulting from material discoloration. Accordingly, paste type restoration material most widely being used in the field of cultural assets preservation treatment was selected and examined the property to select it as an object of comparison. Based on such process, epoxy putty was developed according to the kind of agent, hardener and filler. For the purpose of solving the issues of existing material and allowing the epoxy putty developed to have similar property, property experiments were conducted by selecting agents and hardeners with different characteristics and conditions. The study findings showed that both kinds are paste type that improved work convenience and deflection issue as a result of their work time of within 5~10 minutes that are about 3~10 times shorter than that of existing material. In regards to wear rate for increasing cutting force, it improved by about 3 times, thereby allowing easy molding. For the purpose of improving the issue of surface contamination that occurs during work process, talc and micro-ballon were added as filler to reduce the issue of stickiness and staining on hand. Furthermore, a multi-purpose restoration material with low shrinkage, low discoloration and high cutting force was developed with excellent coloring, lightweight and cutting force features.