• Title/Summary/Keyword: interaction studies

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An analytical approach for offshore structures considering soil-structure interaction

  • Ali Sari;Kasim Korkmaz
    • Advances in Computational Design
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    • v.9 no.1
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    • pp.25-38
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    • 2024
  • This paper presents an advanced analytical approach for the design and analysis of fixed offshore structures with soil structure interaction considered. The proposed methodology involves conducting case studies to illustrate and assess the structural response of a structure considering seven different earthquakes, with the primary goal of ensuring there is no global collapse in the structures. The case studies focus on developing a model for structural analysis and its topside, incorporating nonlinear axial and lateral springs to capture soil-pile interaction. Additionally, mass and damping ratios are considered through the use of dashpots in the analyses. Finite Element Software was employed for structural analyses with detailed modeling, with soil spring nodes applied in the entire structure across various depths. After the finite element analysis was carried out, a sensitivity analysis was conducted to quantify and report the effects of different parameters.

An Interferon Resistance Induced by the Interaction between HCV NS5B and Host p48 (C형 간염 바이러스 NS5B 단백질과 숙주의 p48 단백질의 상호작용에 의한 인터페론 저항성의 유도)

  • Park, So-Yeon;Lee, Jong-Ho;Myung, Hee-Joon
    • Microbiology and Biotechnology Letters
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    • v.36 no.4
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    • pp.353-359
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    • 2008
  • Hepatitis C virus (HCV) is known as the causative agent of blood transmitted hepatitis. Two viral proteins, E2 and NS5A, are known to exert interferon resistance of HCV via PKR pathway. Here, we report a third protein, the RNA-dependent RNA polymerase (NS5B) of HCV, induced interferon resistance inhibiting p56 pathway. p56 was shown to interact with p48 subunit of eukaryotic initiation factor 3 (eIF3). This interaction inhibited formation of ternary complex in translation initiation. Using dual reporter assay system, we observed that the translation decreased when interferon alpha was added to the culture. But, in the presence of HCV NS5B, the translation partly recovered. NS5B and p48 subunit of eIF3 were shown to interact. This interaction seems to inhibit the interaction between p48 and p56. This is the first report that a virus exerts interferon resistance via p56 pathway.

A Structural Relationship Among the Related Variables of Children's Internalizing and Externalizing Problems (아동의 내면화·외현화문제행동 관련변인들 간의 인과적 구조분석)

  • Moon, Dae-Geun;Moon, Soo-Back
    • Korean Journal of Child Studies
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    • v.32 no.5
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    • pp.49-65
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    • 2011
  • The purpose of this study was to investigate the structural relationship between the related variables of children's internalization and externalization of problems. A total of 709 elementary school students residing in Daegu City and Kyungpook province completed questionnaires which assessed family interaction functions, emotional regulation, self-control, and internalization and externalization of problems. The sample variance-covariance matrix was analyzed using AMOS 19.0, and a maximum likelihood minimization function. Goodness of fit was evaluated using the SRMS, RMSEA, and its 90% confidence interval, CFI, and TLI. The results were as follows : First, the function of family interaction, and emotional regulation had a significant direct effect on the internalization of problems. Moreover, emotional regulation, self-control and internalization of problems had a statistically substantial direct effect on the externalization of problems. Second, family interaction functions did not have a statistically significant direct on children's externalization of problems, although it may well have an indirect effect on children's externalization of problems through emotional regulation and self-control. Finally, self-control did not enjoy a direct effect on children's internalization of problems.

Recent Progress of Spray-Wall Interaction Research

  • Lee Sang-Yong;Ryu Sung-Uk
    • Journal of Mechanical Science and Technology
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    • v.20 no.8
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    • pp.1101-1117
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    • 2006
  • In the present article, recent progress of spray-wall interaction research has been reviewed. Studies on the spray-wall interaction phenomena can be categorized mainly into three groups: experiments on single drop impact and spray (multiple-drop) impingement, and development of comprehensive models. The criteria of wall-impingement regimes (i.e., stick, rebound, spread, splash, boiling induced breakup, breakup, and rebound with breakup) and the post-impingement characteristics (mostly for splash and rebound) are the main subjects of the single-drop impingement studies. Experimental studies on spray-wall impingement phenomena cover examination of the outline shape and internal structure of a spray after the wall impact. Various prediction models for the spray-wall impingement phenomena have been developed based on the experiments on the single drop impact and the spray impingement. In the present article, details on the wall-impingement criteria and post-impingement characteristics of single drops, external and internal structures of the spray after the wall impact, and their prediction models are reviewed.

A Study on Teacher Education Programs on Teacher-Child Interaction (교사-유아 간 상호작용에 관한 교사교육 프로그램 연구 분석)

  • Kim, Soojung
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.4
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    • pp.647-654
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    • 2018
  • This study examines the literature regarding teacher-child interaction in the classroom, aiming to find ways to support child-care teachers in improving the quality of teacher-child interaction. The study selected studies exploring teacher-education programs that aim to support child-care teachers in interacting with their children in the classroom in a quality manner. The selected studies were analyzed, by focusing on how the study proposes ways to support child-care teachers in interacting with their children in a quality manner. The results of previous studies are as follows: 1) the literature tends to focus on teachers' language interaction with their children in the classroom; 2) the literature tends to apply a variety of observation tools (or coding schemes) to measure teacher-child interaction in child-care settings; 3) the literature prefers individualized approaches such as mentoring or consulting as ways of supporting child-care teachers in interacting with their children in a quality manner; and 4) the literature aims in general to improve teachers' self-reflection skills.