• Genomics & Informatics
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• v.6 no.3
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• pp.126-129
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• 2008

The robust identification and comprehensive profiling of copy number alterations (CNAs) is highly challenging. The amount of data obtained from high-throughput technologies such as array-based comparative genomic hybridization is often too large and it is required to develop a comprehensive and versatile tool for the detection and visualization of CNAs in a genome-wide scale. With this respective, we introduce a software framework, CGHscape that was originally developed to explore the CNAs for the study of copy number variation (CNV) or tumor biology. As a standalone program, CGHscape can be easily installed and run in Microsoft Windows platform. With a user-friendly interface, CGHscape provides a method for data smoothing to cope with the intrinsic noise of array data and CNA detection based on SW-ARRAY algorithm. The analysis results can be demonstrated as log2 plots for individual chromosomes or genomic distribution of identified CNAs. With extended applicability, CGHscape can be used for the initial screening and visualization of CNAs facilitating the cataloguing and characterizing chromosomal alterations of a cohort of samples.

• Asia-Pacific Journal of Business
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• v.10 no.2
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• pp.1-12
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• 2019

Collaborative research and development (R&D) has been encouraged based on the belief that knowledge spill-over is mutually beneficial for partners. Although the benefits are supported by science and technology policy research, the risk of R&D collaboration has not been extensively discussed. Two independent studies suggest that there are risks associated with the overuse of collaborative research frameworks. Two sets of R&D collaboration data were analyzed: between the national bio-technology research program and 1) Data Envelop Analysis (DEA), and 2) between Stochastic Frontier Analysis (SFA). In the case of SFA, output measures were integrated into a single output, with weights extracted from research programme managers' responses to the questionnaire. While the DEA result demonstrated the inefficiency of collaborative research, SFA did not. Unlike previous research highlighting risks associated with disclosing proprietary R&D and potential conflict of interest, our study indicates that the transaction's social cost affects collaborative research efficiency. Therefore, governments promoting R&D collaborations should be carefully managed, and policy makers must reconsider the strict conditions governing compulsory collaborative R&D programs.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.199-202
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• 1997

We are developing computer integrated polysomnography system. This system integrates conventional polysomnography with computer for data management, automatic analysis, scoring, and data transmission. In the first stage, we have developed the signal interface and user interface for the manual scoring and data management. For the automatic scoring of sleep stage, we have developed the protocol and have applied the analytic method in its primitive form. In the second stage we will develope a partially automatic scoring system, and finalize the fully automatic system in the final third stage.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2008.04a
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• pp.294-299
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• 2008

Nowadays there are numerous factors to design the structure even for simple one, but many parts of the work are similar to the existing or repeated simply. In this case, design of the structure is unnecessarily needed lots of effort and time. To solve difficulties of design, an integrated design automation system for retaining wall structures that widely used is developed. The automation system consists of following items, 1) XML data structure between modules, 2) CAD visualization system to provide drawing sheets, 3) excel solution to provide structural design sheets and bills of quantity, 4) design logic to analysis and calculate behaviors of structure, and 5) GUI to represent data and results for the program.

• Health Policy and Management
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• v.13 no.2
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• pp.67-84
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• 2003

Immunization has been one of the most effective measures preventing from infectious diseases. However, children routine vaccination rate of Korea was 68.2% and it was not higher than expected. Korean government revised the School Health Law for every primary school children to submit the vaccination certificate record from 2005. It is quite important national Infectious disease prevention policy to keep the immunizations rate high and monitor the immunizations rate continuously. To do this, National Institute of Health introduced the National Immunization Registry(NIR) Program at 2000. Objective : The aims of this study was to evaluate the Immunization Registry program which has been implementing since 2000 at the Public Health Centers(PHC). Methods : The mail survey was done from November 2001 to January 2002. 169 (69%) Public Health Centers among 244 PHC were responded. Results : The respondents of PHC sud the Immunization Registry(IR) program had reduced the workload (18.5%). 69.2% said they inputted the immunization data into the IR program after the shots were given. 86.5% said they hadn´t checked or retrieved the children lists who had missed the scheduled immunization. Only 17.2% said the speed of internet for the R program was good. It showed that 20% of respondents hadn´t written down documents, records on immunization any more. Even there were a lot of negative results, the respondents of PHC thought that the IR program was effective. They especially agreed that the IR program could make the job accurate (81.5%), convenient (71.3%), and reduced the chances of making mistakes (71.3%), increase the service quality (78.5%). And they were well adapting the job process of the IR (79.63%). Bivariate analysis showed that the software program was the important determinants of IR success. The only Bit Computer software program has been evaluated to be less satisfactory than the Integrated (Posdata operating system + Bit software) program. Other variables, such as age, duration of present job, and location of PHC (metropolitan, small city, rural area) were not significantly related. Conclusion : It seemed that the success of NIR might depend on the software program. Because Integrated program, which has been developed from 1994, include not only the general operating and management program for PHC but also IR program. It was natural to prefer Integrated program to Bit software program. So we can suggest that it is essential for the NIR to be successful that not only the immunization software program but also hardware equipments and public health information system should be further improved.

• Journal of Korean Society of Rural Planning
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• v.3 no.2
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• pp.90-101
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• 1997

The objectives of the study are to identify the issues and problems encountered in Korea's current integrated rural regional development(IRRD) program and to suggest policy remedies to cope with them. Secondary data and materials ate mainly used for the study. Since the mid-1980s, rural settlement planning has been carried out in the Republic of Korea, In the planning process,'scale of economy'perspectives and settlement policy have been emphasized for increasing the efficiency of investment. During the 1990s, rural settlement and major village development projects have been implemented under the rural structure transformation programs. Agricultural structure adjustment projects for land consolidation and sizable farming have been separated from the rural settlement and mojor village development projects. Based on the evaluative analysis for the rural structure transformation policy and program, some problematic issues were raised as follows: (a) lack of integrative control function in the program'(b) weak linkage between living environment improvement and agricultural development projects: and (c) lack of comprehensive village development planning and implementation system. The policy issues to solve the problems were suggested as follows: (a) adoption of bottom-up approach in new IRRD planning and project system : (b) projection of comprehensive development planning and project at the village level; and (c) introduction of new regional agriculture development projects such as direct payment system for farming in less favorable areas and organic farming.

• Journal of Korean Public Health Nursing
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• v.36 no.3
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• pp.389-401
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• 2022

Purpose: This study was conducted to understand the actual condition and influencing factors of being underweight among older adults in the community based on a survey of national older Korean's data in 2020. Methods: The data from 9,555 older adults in the community were used for analysis. Composite sample analysis was performed with integrated weights applied to the raw data. A Rao Scott-test and logistic regression were performed using SPSS 24.0 for Windows. Results: Underweight older adults in the community were found to have significant differences in age, subjective health status, depression, chronic disease, drinking, exercise, nutrition, chewing, and activities of daily living (ADL). The factors affecting the underweight older adults were age, subjective health status, depression, chronic disease, drinking, exercise, nutrition, chewing, and activities of daily living. Conclusion: A customized program is needed for underweight older adults in the community. In addition, attempts should be made to motivate older adults in the community to continue to participate in the program.

• Journal of Korean Academy of Nursing
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• v.34 no.1
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• pp.81-92
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• 2004

Purpose: The purpose of this study was to identify a path diagram for the influence of family, personality, sexual abuse, drug abuse, coping strategies, and aggressive impulsiveness on aggression, and to develop a sublimation program for Korean adolescent's aggression. Method: Data was collected by self-report questionnaires. Subjects consisted of 2,111 adolescents. A proportional stratified random sampling method was used. The major instrument was the Mental Health Questionnaire for Korean Adolescents, and the Cronbach's Alpha ranged from .54 to .95 for each subscale. Statistical methods were Chi-square, correlation analysis, and path analysis. Results: The strongest contributing variables on aggression were person-related aggressive impulsiveness, antisocial personality, self-injured aggressive impulsiveness, gender, sexual abuse, psychosomatic symptoms II, drug abuse, age, parent-child relationship, alcohol abuse and cognitive avoidance coping strategies in the order named. Also the author developed a multi-systemic sublimation program for Korean adolescents's aggression. The multi-systemic sublimation program involves four domains including adolescents, parents, peers and community, and has several therapeutic sub-programs for each domain. Conclusion: The ecology of human development is composed of multiple, integrated levels of organization, including biological, individual-psychological, social-interpersonal, cultural, and historical levels. Therefore, this multi-systemic sublimation program will prevent and decrease the rate of aggressive behavior among Korean adolescents.

• Journal of Korean Clinical Health Science
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• v.4 no.1
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• pp.504-509
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• 2016

Purpose. This study aims to present basic data to develop programs suitable to the characteristics of elderly people through a meta-analysis of effectiveness of variables related to psychological effects of programs of elderly people conducted in past 15 years. Methods. The analysis subjects are total 229 articles related to the psychological effects of programs for elderly people and submitted for master or doctor degrees or published in academic journals. CMA2 is used for the analysis. Results. The results of this study shows lower variables of the psychological effect promoting factor group that are highly effective for Life Satisfaction, Self-Efficacy, Self-Respect and Self-Integration and lower variables of suppressing factor group that are highly effective for Loneliness, Tension, Weakness, Anger and Depression. For the effect scale of psychological effect promoting factors, Arts is shown to be the highest followed by Exercise, Consultation, Recollection, Others and Recreation in order. For the effect scale of suppressing factors, Consultation is shown to be the highest followed by Recollection, Arts, Exercise, Others and Recreation) in order. Conclusions. This study has its own meaning for establishing integrated factors of psychological effects of programs for elderly people and presenting realistic data for planing programs suitable for various desires of elderly people.

• Computational Structural Engineering
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• v.8 no.1
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• pp.161-172
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• 1995

An Integrated processing system for finite element structural analysis has been studied. It is designed to control integratedly the preprocessing, the execution and the postprocessing of a finite element structural analysis program on Windows. It becomes a better graphic user interface(GUI) for the concurrent representation of various inputs and outputs through the dialog-type on multi-windows by the multi-tasking and the object linking and embedding(OLE). Data input can be done easily through menus, dialog boxes and automatic stepwise inputs on the multiple windows, and then output results can be seen with input data on the same screen. Efficiency and validity of the system were examined by solving several numerical examples.