• Asian-Australasian Journal of Animal Sciences
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• 제25권10호
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• pp.1411-1418
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• 2012

The objective of the present study was to investigate the relationships between terpenes… intake and their presence in animal tissues (blood and milk) as well as in the final product (cheese). Eight dairy goats were divided in two balanced groups, representing control (C) and treatment (T) group. In T group oral administration of a mixture of terpenes (${\alpha}$-pinene, limonene and ${\beta}$-caryophyllene) was applied over a period of 18 d. Cheese was produced, from C and T groups separately, on three time points, twice during the period of terpenes… oral administration and once after the end of experiment. Terpenes were identified in blood by extraction using petroleum ether and in milk and cheese by the use of solid phase micro-extraction (SPME) method, followed by GC-MS analysis. Chemical properties of the milk and the produced cheeses were analyzed and found not differing between the two groups. Limonene and ${\alpha}$-pinene were found in all blood and milk samples of the T group after a lag-phase of 3 d, while ${\beta}$-caryophyllene was determined only in few milk samples. Moreover, none of the terpenes were traced in blood and milk of C animals. In cheese, terpenes' concentrations presented a more complicated pattern implying that terpenes may not be reliable feed tracers. We concluded that monoterpenes can be regarded as potential feed tracers for authentification of goat milk, but further research is required on factors affecting their transfer.

• 한국환경보건학회지
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• 제46권4호
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• pp.368-375
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• 2020

Objectives: Some animal studies have reported that methyl mercury causes developmental toxicities such as placental and fetal weight loss, but the mechanism is still unclear. This study aimed to investigate the developmental toxicities of methyl mercury, focusing on placental endocrine function and fetal growth retardation in rats. Methods: Positively same-time-mated female Sprague-Dawley rats were purchased on gestational day (GD) eight and treated with 0, 5, 10 and 20 ppm of methyl mercury (n=5) dissolved in tap water from GD eight through 19. During treatment, the drinking water (methyl mercury) intake and body weight of each pregnant rat was measured daily. On day 19, caesarean sections were performed and blood samples were collected. Developmental data such as placental and fetal weights, fetus numbers, and placental efficiency (fetal weight/placental weight) were also collected. Placental prolactin-growth hormone (PRL-GH) family, such as placental lactogen (PL) -Iv, II, and prolactin-like protein (PLP) -B, levels in serum were analyzed by ELISA. Also, placental tissues were assigned to histochemistry. Results: The mean cumulative methyl mercury exposure for the 5, 10, and 20 ppm groups were 2.37, 4.63, and 9.66 mg, respectively. The mean daily exposure of the 5, 10, and 20 ppm groups were 0.24, 0.47, and 0.97 mg, respectively. Maternal body weight increased in accordance with GD. There was no significant difference in weight gain among the experimental groups. Histopathologic changes were not observed in placental tissues among the experimental groups. However, mean placental and fetal weights were lower in the 10 and 20 ppm exposed groups compared to the control. Placental efficiency was also lower in the 10 and 20 ppm exposed groups compared to the control. Serum PL-Iv and II levels were lower in the 10 and 20 ppm exposed groups than the control, in accordance with the changing pattern of placental and fetal weights and placental efficiency. Conclusion: The inhibitory effects of methyl mercury on the serum levels of placental PRL-GH family such as PL-Iv and II may be secondary leads to the reduction of placental efficiency and fetal growth retardation in rats.

• 대한지역사회영양학회지
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• 제7권5호
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• pp.654-663
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• 2002

The purpose of this study is to investigate how the lifestyles of food habits of college students relate to constipation. The results were as follows 1) All the total respondents were 541 college students.220 (40.8%) respondents were male and 321 (59.2%) respondents were female. Based on their BMIs, 55.5% of the female respondents were under-weight (BMI < 20), 16.8% of the male respondents were under-weight, as well. These results point out the fact that a high percentage of female college students are under-weight, compared to male of students. 2) Of the respondents, 59.0% reported having 1 or 2 meals per day, but their eating patterns were irregular. Of the respondents, 71.2% preferred white rice with their meals. Of the respondents,51.2% reported that they skipped breakfast. The main reasons why these respondents skipped breakfast were either that they were in a busy (44.7%), or it was their habit (38.4%). The response that their meals were nutritionally balanced was 34.6%, and the student who thought that their own meal pattern was healthful was 8.0%. 3) This research also focused on body image among female college students, and the results indicate that the majority of female respondents (62.5%) felt that they were overweight (very fatty or fatty) and 90.1% of the female respondents indicated they were interested in dieting (interest or very interest). Most of the students were involved in light or medium activity (94.2%) or no exercise (75.6%). The ratio of those who exercised was everyday only 33.6%.4) Of the respondents,48.7% reported that they had difficulty evacuating (every time very difficult, every time difficult and sometimes difficult) and 50.3% of the students reported that their bowel movements were irregular. 5) Of the females,8.2% and Of the males,0.5% were regarded as constipated.6) The life habit factors that influenced constipation were skipping breakfast, the amount of water intake and exercise.

• 한국발생생물학회지:발생과생식
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• 제6권2호
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• pp.83-88
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• 2002

월동기 90일 동안 transgenic coho salmon의 사료섭식량, 성장도 및 혈중 호르몬 수준을 파악하였다. 실험 종료시 실험구별 사료섭식량은 비교해 볼 때 tGH구가 Wild구보다 약4배 정도 높게 나타났지만, 사료효율의 경우 오히려 tGH구가 Wild구보다 1.1 배 낮은 것을 알 수 있었다. 한편 생존률은 tGH구가 Wild구보다 높게 나타났고, 성장은 tGH구가 길이에 있어 1.4배, 무게의 경우 약 3배 빠르게 나타났으며, 비만도 역시 tGH구가 Wild구보다 높게 나타났다. 실험구별 성장에 따른 호르몬 분석 결과, GH와 thyroid hormone의 농도는 tGH구가 Wild구에 비해 약 2배 정도 높은 값을 나타냈었다. 실험구별 형태적 특징을 관찰해 본 결과, tGH구들은 Wild구와 비교해 머리가 몸에 비해 상대적으로 크면서 꼬리지느러미의 가랑이 부분이 중심선으로 위, 아래가 확연히 분리되어 있지 않았다. 또한 몸통 부분은 길이에 비해 상대적으로 체고가 높게 나타났다.

• 대한지역사회영양학회지
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• 제17권3호
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• pp.280-289
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• 2012

The objective of this research was to explore the influences of 'having a meal with someone' on individuals' eating pattern. Eating is not a simple matter of energy intake but also serves to anchor daily routines being cultivated by people and society. This study was conducted using a cross-sectional eating behavior survey of university students (N = 893, 380 men, 513 women) aged 20 to 24 years. Results were analyzed and presented as frequencies, means and ${\chi}^2$-test with SPSS 14.0. Differences in dietary habits by commensality and solo-eating were observed; Students who ate alone, spent 15 min for a meal and ate convenience food items when they didn't feel hungry. Compared to students who ate alone, those who ate together with someone spent 30 min for a meal and ate more amount of food. Eighty percent of respondents ate more various menus in commensality than solo-eating. They felt lonely when they ate alone and preferred to eat together. In conclusion, university students start to decide and select their own meals by themselves after junior and high school food services which are fixed with regard to menu and the amount. Dietary habits of Koreans rapidly changed concomitant with social changes over the past half century. Governments and health experts recognize that unbalanced meals cause lifestyle-related diseases, in particular obesity. Our research findings will contribute to more comprehensive efficient nutrition education programs in order to prevent obesity and other lifestyle-related diseases in early stages of adulthood.

• Environmental Engineering Research
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• 제21권4호
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• pp.373-383
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• 2016

Cheonsu Bay, one of the most important in Korea as a coastal fishery is a semi-enclosed bay that is surrounded by large farmlands and industrial areas. This coastal environment has been affected by anthropogenic pollutants, such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). The objectives of this study were to investigate the distribution of PCBs and OCPs in sediment, Manila clams, and mussels from Cheonsu Bay; the accumulation pattern of these chemicals in these bivalves in relation to seasonal changes; and the ecological risk from sediments and the risk to the Korean population from the consumption of these bivalves. The levels of ${\Sigma}PCBs$, ${\Sigma}DDT$, and ${\Sigma}HCHs$ were 69.3-109, 40.3-49.3 and 6.25-17.8 ng/g lipid in Manila clams, and 70.6-159, 38.6-102 and 9.00-13.5 ng/g lipid in Mussels. Significant seasonal variations in PCBs and OCPs concentrations were observed in the two bivalves, suggesting that the accumulation of PCBs and OCPs in these species is related to their spawning times. The dietary intake of these two bivalves and the resulting lifetime cancer risk (LCR) and non-cancer risk were calculated for the human population. The consumption of these bivalves seemed to be safe in relation to human health with negligible LCR and non-cancer risk.

• 대한한의학원전학회지
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• 제25권3호
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• pp.127-147
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• 2012

Objective : Methods of Jang Cong-zheng's treatment related to his theories include of promoting the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). He succeeded Liu wan-su(劉完素) as promoter of fire-heat pattern theory(火熱論), thereby emphasizing six qi(六氣), especially fire(火) and dampness(濕), as pathogens. He suggested that physician should treat patients whose diseases occurred due to fire(火) and dampness(濕) with promoting the sweating(汗)-vomiting(吐)-purgation(下) methods, which would remove pathogen qi(邪氣) and help circulation of qi and blood, therefore getting them back healthy qi(正氣). Method : I will try to describe the Jang Cong-zheng's treatment in "Ru-Men-Shi-Qin", and I would like to explain the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). Result : For emotional diseases, he suggested that most should be caused by heart fire(心火) so they should be treated with methods of suppressing heart fire and medication would be using cool and cold herbal drugs which lead to clear heart fire. Conclusion : Theories of Zhang zi-he(張子和) can be applied to nurturing for modern world maintaining and improving health by his care methods. People these days suffer usually from excess intake or unbalanced diet problem, so wastes matter and pathogenic qi can be driven out of the human body by applying the sweating-vomiting-purgation methods. His medical theories could contribute to modernization of traditional medicine this way.

• 대한한의학원전학회지
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• 제33권4호
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• pp.147-165
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• 2020

Objectives : The meaning of the verses '久而增氣' and '氣增而久' from the 『Suwen·Zhizhenyaodalun』 were studied to complement previous annotations. Methods : Based on problems uncovered in previous annotations, the verses "久而增氣, 物化之常也" and "氣增而久, 夭之由也" were examined in detail. Results & Conclusions : Previous annotations on the verse "久而增氣, 物化之常也" have conflicting opinions. Therefore, related contents in the 『Huangdineijing』 were examined to resolve and complement existing interpretations. The meaning of '久' in the phrase "久而增氣, 物化之常也," not only has a temporal meaning but also refers to the Jing process[精化｣. The Jing process is where the Jing Qi is used to produce Jing through a feedback process that results in enlivening materials such as Jing, Qi, and Blood. The phrase "氣增而久, 夭之由也" refers to an early death caused by expansion of rough Qi that has failed to go through the Jing process because of excessive greed and failure to follow the seasonal principle. These phrases from the 『Suwen·Zhizhenyaodalun』 reminds us that the Qi's Jing process is an important factor in determining longevity, shedding new light on themes such as the pattern of food intake, cultivation, longevity, treating before illness, prevention, etc., for today.

• Journal of Nutrition and Health
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• 제39권8호
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• pp.748-755
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• 2006

The purpose of this study was to find out effects of treatment of ginsenoside Re, Rc and EGCG on mRNA expressions of leptin, hormone sensitive lipase (HSL) and resistin in 3T3-L1 adipocytes. The concentrations of EGCG were treated with $0.01{\times}10^{-7},\;0.1{\times}10^{-7},\;1{\times}10^{-7}\;and\;1{\times}10^{-6}\;or\;100{\mu}g/ml$ ginsenoside Re, Rc in culture cell for 13 days. mRNA expression of leptin wasn't expressed in preadipocyte but according to differentiation of adipocyte, the that of mRNA expression was decreased at gensenosids or EGCG treated cells compared with non treated adipocyte. Expression of HSL mRNA was increased in G-Re, G-Rc and EGCG treated cells compared with non treated cells. The resistin level was significantly decreased in adipocytes treated with G-Re, G-Rc and EGCG. These pattern was similar to leptin expression. These results support that treatment of gensenosides or EGCG in 3T3-L1 adipocyte resulted to affect of leptin and resistin as well as HSL mRNA levels, accordingly, levels of leptin and HSL will be acted by signalling body fat stores to the hypothalamus which in turn regulates food intake andenergy expenditure to maintain body weight homeostasis. And also regulation of resistin mRNA will prevent to diabetics attacked with obesity. In conclusion, we suggest that consumption of ginseng saponine or EGCG might prevent human diabetics or/and obesity.

• Nutrition Research and Practice
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• 제5권2호
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• pp.124-131
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• 2011

Because excessive consumption of sugar-sweetened beverages may reduce the quality of nutritional intake, this study examined the consumption patterns of commercial beverages, lifestyle, dietary habits, and perception of sweet taste. Participants were 407 male university students in Kyeooggido, Korea, and information was collected by self-administered questionnaire. Among them, 58 nonsmokers volunteered to participate in the taste test. Participants were divided into three groups according to the frequency of commercial beverage consumptions: 120 rare (< 1 serving/week), 227 moderate (1-3 servings/week) and 133 frequent (> 3 servings/week) consumption groups. More subjects from the rare consumption group chose water, tea, and soy milk, and more from the frequent consumption group chose carbonated soft drinks and coffee (P=0.031) as their favorite drinks. Frequent consumption group consumed fruit juice, coffee, and sports and carbonated soft drinks significantly more often (P=0.002, P=0.000, P=0.000, respectively), but not milk and tea. Frequent consumption group consumed beverages casually without a specific occasion (P=0.000) than rare consumption group. Frequent drinking of commercial beverages was associated with frequent snacking (P=0.002), meal skipping (P=0.006), eating out (P=0.003), eating delivered foods (P=0.000), processed foods (P=0.001), and sweets (P=0.002), and drinking alcoholic beverages (P=0.029). Frequent consumption group tended to have a higher threshold of sweet taste without reaching statistical significance. The results provide information for developing strategies for evidence-based nutrition education program focusing on reducing consumption of unnecessary sugar-sweetened commercial beverages.