• 한국식품과학회지
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• 제27권4호
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• pp.576-581
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• 1995

피부조직에서 추출한 콜라겐의 유동특성을 검토하여 콜라겐을 효율적으로 활용할 수 있는 기초자료를 얻고자 하였다. 콜라겐의 점도는 동물의 나이와 성(sex), 콜라겐 종류에 따라 차이를 보였다. 즉, 주령에 따라서는 콜라겐의 종류에 관계없이 $6{\sim}12$주령의 것이 비교적 높게 나타났으며, 동일 주령에서는 수컷의 점도보다 암컷의 점도가, 그리고 불용성 콜라겐의 점도보다 산가용성 콜라겐의 점도가 높게 나타났다. 콜라겐 용액은 Bingham plastic 및 thixotropic 유체의 특성을 나타냈으며, 온도, pH, 에탄올 농도 및 콜라겐 농도에 따라 점도 변화가 뚜렷하게 나타났다. 즉, 콜라겐 농도를 6%까지 높일 경우 콜라겐 용액의 점조도는 직선적으로 증가하는 경향(산가용성 콜라겐 r=0.972, 불용성 콜라겐 r=0.957)을 나타냈는데, 산가용성 콜라겐의 증가속도가 불용성 콜라겐의 경우보다 높게 나타났다. 온도 증가에 따라 콜라겐 용액의 점조도는 감소하였으며 특히, 산가용성 콜라겐에서는 $30{\sim}40^{\circ}C$ 온도구간에서 점조도가 급격히 감소하였다. pH에 따라 산가용성 콜라겐의 점조도는 pH 6에서 최대치를 보였고, pH 10 부근에서 다시 증가하는 biphasic 현상을 나타냈으나, 불용성 콜라겐의 경우는 pH에 큰 영향을 받지 않았다. 에탄올 농도에 따른 산가용성 콜라겐과 불용성 콜라겐의 점조도는 에탄올 농도 $40{\sim}60%$ 수준에서 높게 나타났다.

• 청정기술
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• 제9권3호
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• pp.133-144
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• 2003

본 연구는 불용성 산화물계 촉매전극을 제조하고 이를 이용하여 난분해성 유기물질을 포함하고 있는 염색폐수를 대상으로 전해처리 실험을 수행하였으며, 이때 전해시스템에 사용된 가용성 전극(Fe, Al)과 불용성 전극 [SUS, R.C.E(Replaced Catalyst Electrode);금속산화물 전극]에 대한 환경오염물질의 처리 효율성과 각 전극에 대한 유용성 여부를 비교 고찰하였고, 또한 전해 처리 효율성을 극대화하기 위한 전해처리 조건들에 관해 조사하였다. 이 결과 오 폐수 처리를 위한 전기분해 공정의 실용화에 있어서 가장 큰 문제점 중의 하나인 전극 안정성은 불용성 산화물계 촉매전극을 제조 사용함으로써 해결될 수 있었으며 이에 따른 실험결과는 다음과 같다. 1. 불용성 전극인 R.C.E 제조시 $RuO_2-SnO_2-IrO_2-TiO_2$의 4성분계 혼합물의 몰 비가 70/20/5/5이 될 때 내구성이 가장 양호함을 확인 할 수 있었다. 2. 불용성 전극인 R.C.E를 이용한 염색폐수 처리 시 전극간 거리 5mm, 전해시간 60분, 인가전압 10 V, 처리 용량 $0.5{\ell}$의 실험 조건에서 90% 이상의 양호한 CODMn 처리효율을 얻을 수 있었으며 또한 T-N 제거에도 양호한 결과를 얻을 수 있었다.

• 한국식품영양학회지
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• 제8권4호
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• pp.280-288
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• 1995

Because yeast is rich in vitamins, nucleotides and essential amino acids, it has been used as a nutrient and dietary supplements. Particularly yeast extract functions as a seasoning, flavor enhancer in meats. In this study, naturally occurring insoluble components during yeast extract process by autolysis were microanalyses by using SEM, XRD, HPLC, GC, FT-lR and DSC. On the basis of useful datas, authors have characterized the analytical points for the purpose of improving products in the preparation of yeast extract.

• 한국산학기술학회논문지
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• 제4권3호
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• pp.260-262
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• 2003

A thermal vapor deposition method for crystallization of insoluble analytes with matrix is established as a new sample preparation method for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). A mixture of mono, bis and tris(p-ethyl benzylidene) sorbitols was incorporated into microcrystals of ferulic acid, which was confirmed by confocal micrographs. Molecular masses of sorbitol derivatives were determined in this way by MALDI-MS without thermal decomposition.

• 품질경영학회지
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• 제16권1호
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• pp.15-22
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• 1988

This paper analysis the process capability by applying experiment design to control alcohol in soluble matter mixing process of laundry soap. The results are summarized as follows: (1) Alcohol insoluble matter shows the tendency of increasing according to the mixing temperature (A) and beating velocity (B). (2) The most suitable working condition of the mixing process is $A_2B_2$, and 95% confidence limit of alcohol insoluble matter is $22.06{\pm}0.77%$. (3) The process capability index ($C_p$) of the mixing process is improved from 0.64 to 1.68.

• 약학회지
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• 제12권3_4호
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• pp.85-88
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• 1968

To select sclerotia to be used for strain isolation, water-soluble and water-insoluble alkaloids contents of the sclerotia of ergot fungus were determined. The sclerotia parasitic on the genus Elymus were found to contain greater amount of the alkaloids, up to 1.44%, than the sclerotia from the genus Agropyron. The major portion of the total alkaloid contents was the water-insoluble alkaloids. No correlation was found between the alkaloid contents and the lipid contents of the sclerotia analyzed.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2003년도 춘계학술발표논문집
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• pp.311-313
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• 2003

A thermal vapor deposition method for crystallization of insoluble analysis with matrix is established as a new sample preparation method for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). A mixture of mono, bis and tris(p-ethyl benzylidene) sorbitols was incorporated into microcrystals of ferulic acid, which was confirmed by confocal micrographs. Molecular masses of sorbitol derivatives were determined in this way by MALDI-MS without thermal decomposition.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.295.1-295.1
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• 2003

A suitable model for the estimation of the drug release from nanoparticles has been varied and problematic, especially for the release from lipid nanoparticles containing water-insoluble drugs, due to the difficult particle collection from the release medium. Dialysis membrane has been widely used for the release test from colloidal carrier systems. The amount of drug from the carriers in normal dialysis diffusion technique was very low typically. (omitted)

• 한국재료학회지
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• 제22권2호
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• pp.86-90
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• 2012

Insoluble catalytic electrodes were fabricated by RF magnetron sputtering of Pt on Ti substrates and the performance of seawater electrolysis was compared in these electrodes to that is DSA electrodes. The Pt-sputtered insoluble catalytic electrodes were nearly 150 nm-thick with a roughness of $0.18{\mu}m$, which is 1/660 and 1/12 of these values for the DSA (dimensionally stable anodes) electrodes. The seawater electrolysis performance levels were determined through measurements of the NaOCl concentration, which was the main reaction product after electrolysis using artificial seawater. The NaOCl concentration after 2 h of electrolysis with artificial seawater, which has 3.5% NaCl normally, at current densities of 50, 80 and 140 mA/$cm^2$ were 0.76%, 1.06%, and 2.03%, respectively. A higher current density applied through the electrodes led to higher electrolysis efficiency. The efficiency reached nearly 58% in the Pt-sputtered samples after 2 h of electrolysis. The reaction efficiency of DSA showed higher values than that of the Pt-sputtered insoluble catalytic electrodes. One plausible reason for this is the higher specific surface area of the DSA electrodes; the surface cracks of the DSAs resulted in a higher specific surface area and higher reaction sites. Upon the electrolysis process, some Mg- and Ca-hydroxides, which were minor components in the artificial seawater, were deposited onto the surface of the electrodes, resulting in an increase in the electrical resistances of the electrodes. However, the extent of the increase ranged from 4% to 7% within an electrolysis time of 720 h.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5785-5790
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• 2012

The use of chemotherapeutics induces cardiotoxicity and affects immune functions, therefore development of combinatorial agents against cardiotoxicity and immunosuppression needs to be explored. Previous studies of the hexane insoluble fraction (HIF) of an ethanolic extract of Ficus septica leaves showed anticancer effects singly and in combination with doxorubicin on T47D breast cancer cells. In this present study, it was evaluated for its immunomodulatory activities in doxorubicin-treated rats. Thirty male Sprague Dawley rats were divided into five groups consisting of six rats each as follows: Group 1, receiving oral saline 10 ml/kg BW (control group); Group 2, receiving HIF dose 750 mg/kg BW orally, once daily; Group 3, receiving HIF dose 1.500 mg/kg BW orally, once daily; Group 4, given oral saline 10 ml/kg BW (normal group); Group 5, receiving HIF dose 1.500 mg/kg BW orally, once daily. The rats of group 1-3 were intramuscularly administered with doxorubicin at a dose of 4.67 mg/kg BW at the days 1 and 4 to suppress immune functions. Concomitantly, the rats were treated with saline or HIF for seven consecutive days (1 to 7). Treatment of HIF succeeded in reducing side effects of doxorubicin based on increasing lymphocyte density and phagocytosis activity and capacity of macrophages, as well as increasing the CD8+ blood level and decreasing spleen IL-10 expression. Hexane insoluble fraction of of ethanolic extract of Ficus septica leaves has potential as a protective agent combined with doxorubicin.