• Korean Journal of Microbiology
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• v.55 no.1
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• pp.17-24
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• 2019

Bacteria in the polar region are under strong light and ultraviolet radiation. In this study, we investigated the effects of light on the growth of a psychrophilic bacterium, Sphingomonas sp. PAMC 26621, isolated from an Arctic lichen Cetraria sp. The growth of the strain in the light was lower than that in the dark. Surprisingly, thiamine increased the growth of Sphingomonas sp. PAMC 26621 in M9 minimal medium under light conditions. Thiamine increased the growth of the strain in a concentration-dependent manner along with ascorbic acid. N-acetylcysteine had no effect on the growth of the strain in the light. Thiamine and ascorbic acid also increased the activities of glucose-6-phosphate dehydrogenase and superoxide dismutase. The results of this study indicate that thiamine provided by the lichen symbiosis system plays an important role in light-induced oxidative stress in this Arctic bacterium as an antioxidant. Our study provide insight into the biochemistry and physiology of Arctic bacteria under strong light and ultraviolet radiation.

• Journal of the Korean society of biological therapies in psychiatry
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• v.24 no.3
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• pp.163-172
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• 2018

Objectives : The aim of this study was to examine associations between quality of life in patients with schizophrenia and their family relationships. Methods : A total of 68 patients with schizophrenia participated in the study. Socio-demographic and clinical data were collected, as well as results from the Subjective Well-being under Neuroleptic Treatment Scale-Short Form(SWN-K), Family Emotional Involvement and Criticism Scale(FEICS), a visual analogue scale for evaluating the degree of perceived criticism(VAS), the Family Adaptability and Cohesion Evaluation Scale(FACES), Beck Cognitive Insight Scale(BCIS), and Rosenberg Self Esteem Scale(R-SES). Psychiatrists administered the Positive and Negative Syndrome Scale and the Calgary Depression Scale for Schizophrenia(CDSS), and collected a history of previous suicide attempts. Results : The SWN-K total scores showed significant negative correlations with scores on the FEICS perceived criticism, CDSS, and VAS measures and significant positive correlations with scores on the R-SES, FACES, and BCIS. Multiple regression analysis revealed that FEICS perceived criticism, FACES, and BCIS scores were significantly associated with SWN-K scores. The FACES total score was significantly lower in patients with a history of previous suicide attempt. Conclusion : The quality of life of patients with schizophrenia was negatively associated with greater perceived familial criticism and positively associated with better family cohesion and higher patient insight. In patients with a history of suicide attempts, family adaptability and cohesion were significantly low.

• Journal of Animal Science and Technology
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• v.62 no.6
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• pp.765-776
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• 2020

The retinal degenerative disease, progressive retinal atrophy (PRA) is a major reason of vision impairment in canine population. Canine PRA signifies an inherently dissimilar category of retinal dystrophies which has solid resemblances to human retinis pigmentosa. Even though much is known about the biology of PRA, the knowledge about the intricate connection among genetic loci, genes and pathways associated to this disease in dogs are still remain unknown. Therefore, we have performed a genome wide association study (GWAS) to identify susceptibility single nucleotide polymorphisms (SNPs) of PRA. The GWAS was performed using a case-control based association analysis method on PRA dataset of 129 dogs and 135,553 markers. Further, the gene-set and pathway analysis were conducted in this study. A total of 1,114 markers associations with PRA trait at p < 0.01 were extracted and mapped to 640 unique genes, and then selected significant (p < 0.05) enriched 35 gene ontology (GO) terms and 5 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways contain these genes. In particular, apoptosis process, homophilic cell adhesion, calcium ion binding, and endoplasmic reticulum GO terms as well as pathways related to focal adhesion, cyclic guanosine monophosphate)-protein kinase G signaling, and axon guidance were more likely associated to the PRA disease in dogs. These data could provide new insight for further research on identification of potential genes and causative pathways for PRA in dogs.

• Journal of Korean Society for Quality Management
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• v.50 no.4
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• pp.863-876
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• 2022

Purpose: The purpose of this study is to propose the product quality satisfaction index based on multiple linear regression using customer reviews. Methods: The proposed framework is composed of four steps. First, we collect online reviews and divide it into insight phrases. The insight phrases are classified using product attribute dictionary and sentiment analysis is conducted. Second, the importance of attributes is calculated in consideration of both regression coefficient and frequency. Third, the positive rate is calculated concerning sentiment analysis result. Therefore, the quality satisfaction index is measured by the weighted sum of importance and positive rate in the last step. Results: We conduct a case study using 2-years(2020, 2021) of Samsung TV reviews to confirm the effectiveness of the proposed methodology. As a result, we found that Picture quality is the most crucial attribute in TV evaluation. The importance of Gaming and content has grown up as the positive rate has also increased. Therefore, the overall satisfaction of TV has increased in 2021 compared to 2020. Conclusion: The result of this study shows that the proposed index reveals the customer's mind efficiently and can be explained by the importance and positive rate of each attribute. By using the proposed index, companies are able to improve and the priority of improvement can be determined.

• Herbal Formula Science
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• v.31 no.1
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• pp.67-79
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• 2023

Objectives : The purpose of this study was to confirm the consumption trends of Korean medicine for health food consumption of consumers by using the Naver DataLab Shopping Insight service. Methods : In this study, the search data for the category of Korean herbal ingredients in the health food field of Naver Datalab shopping insight site was collected and sorted in order of frequency from August 1st, 2017 to June 22nd, 2022. The frequently searched keywords were organized based on the inclusion of Korean Pharmacopoeia (KP), Korean Herbal Pharmacopoeia (KHP), and Food Code. Results : 67,804 keywords were collected, and the most frequent keywords appearing for more than 200 days among the top 500 were 827 (1.184%). Among the frequent keywords, there were 149 keywords related to traditional medicine names included in the KP and KHP, and five prescriptions were included. 60 keywords were not included in the KP and KHP, and the keyword with the highest search frequency was "kujibbongnamu" (Maclura tricuspidata). Conclusions : The findings of this study provide information on the consumer's interest in traditional korean medicine (TKM) and natural products (NP), and can be used as a basis for understanding the demand for TKM and NP in the online shopping market.

• Journal of Service Research and Studies
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• v.11 no.2
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• pp.95-105
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• 2021

The purpose of this study is to improve the accuracy of service satisfaction by utilizing KSC (Kano, Score Model, Concept Position) analysis methods in order to present various fitness center service models for healthy new silver generation centered on P fitness center which runs six branches in Busan. Double Diamond-based methods led to a case study focused on the P fitness center's Yeon-san branch which well leading in a wide variety of leisure infrastructures for the senior citizens. Throughout this study, based on the insights extracted from the customers were culminating in nine service design models from the perspective of administrators and trainers. The final derived nine models have been evaluated by Kano's satisfaction evaluation, Concept score, and Concept position evaluation. All of the nine models results indicated as valid except for models 3 and 6. Finally, an implementation roadmap was proposed by dividing it into investment cost and effectiveness.

• Journal of Service Research and Studies
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• v.11 no.3
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• pp.17-30
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• 2021

In the context of Sharing Accommodation has become a new type of accommodation choice for customers. The purpose of this study is to improve the existing defects of Sharing Accommodation Services through insight into the pain points of customer experience, so as to improve customer satisfaction. In this study, Airbnb and Tujia were selected as the subjects for comparative study. By collecting and sorting out references, the research background of Sharing Accommodation is analyzed in depth. Research methods of Service Design, such as Customer Journey Map and Service Blueprint, are adopted to gain insight into customer needs, identify pain points and propose hypothesis of service optimization. Tools such as Kano Model and Potential Customer Satisfaction are used to test and determine three schemes for optimizing the service. Finally, the results are displayed through Service Scenario. The research results can help operators of Sharing Accommodation to identify and improve the elements of service and provide a higher quality customer experience, thus promoting the healthy development of Sharing Accommodation market.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.305-310
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• 2023

This study is an example of a class of bibliotherapy through Lee Chung-joon's novel Snowy Road. Bibliotherapy proceeds through the process of identification, catharsis, expression, insight, and application through reading. Through research, students objectively examine the situation of the character in the novel and compare it with their own situation. Students evaluate the situation of the character in the novel, experience the various life positions of the character in the novel by answering "What would you do if I were a character in the novel," and express their willingness to live differently from their lives. At the same time, I look into my relationship with my parents and seriously think about whether there is a problem and how to solve it if there is one. Through this process, students specifically suggest ways to think about and solve their emotions and problems. In the end, students' hurt feelings can be partially or sufficiently healed through reading. Through this study, it is expected that the method of bibliotherapy will be more concrete and develop in a positive direction.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.127-131
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• 2015

In spite of the socio-economic benefits of the construction industry, it accounts for many deaths, injuries and illnesses in many countries. In developing countries like Vietnam, the situation is even worse. Health and safety (H&S) management plays a crucial role in the efforts to improve H&S performance as it contributes to mitigating the risks of occupational injuries and illnesses. However, within the wider H&S literature in Vietnam, there is no insight into the current state of affairs of H&S management, particularly in terms of the management practices that need attention in order to improve H&S management across the construction sector. This study therefore presents the findings of an inquiry into the H&S management practices of contractors in Vietnam. The study employed a questionnaire survey which yielded 58 responses from contractors, particularly those operating in Southern Vietnam. Some commonly implemented H&S management practices by the contractors are: provision of personal protective equipment (94%), allocation of H&S supervisor on site (90%), and displaying of company H&S policy on construction sites, company website, and head/branch offices (86%). Some of the less implemented practices are: networking/engaging with other companies/institutions (e.g. government offices) about H&S issues (39%), rewarding workers for safe work behaviour (39%), reviewing and updating H&S plans (48%), and displaying regulatory H&S posters on site (45%). The findings have provided some insight into the current state of affairs of the H&S management practices of contractors in Southern Vietnam and could thus inform efforts by industry stakeholders to improve the aspects of H&S management that are lagging.

• Journal of Pharmacopuncture
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• v.26 no.4
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• pp.307-318
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• 2023

Objectives: Bacterial biofilm is regarded as a significant threat to the production of safe food and the arise of antibiotic-resistant bacteria. The objective of this investigation is to evaluate the quorum sensing inhibitory effect of Nepeta curviflora methanolic extract. Methods: The effectiveness of the leaves at sub-inhibitory concentrations of 2.5, 1.25, and 0.6 mg/mL on the virulence factors and biofilm formation of P. aeruginosa was evaluated. The effect of N. curviflora methanolic extract on the virulence factors of P. aeruginosa, including pyocyanin, rhamnolipid, protease, and chitinase, was evaluated. Other tests including the crystal violet assay, scanning electron microscopy (SEM), swarming motility, aggregation ability, hydrophobicity and exopolysaccharide production were conducted to assess the effect of the extract on the formation of biofilm. Insight into the mode of antiquorum sensing action was evaluated by examining the effect of the extract on the activity of N-Acyl homoserine lactone (AHL) and the expression of pslA and pelA genes. Results: The results showed a significant attenuation in the production of pyocyanin and rhamnolipid and in the activities of protease and chitinase enzymes at 2.5 and 1.25 mg/mL. In addition, N. curviflora methanolic extract significantly inhibited the formation of P. aeruginosa biofilm by decreasing aggregation, hydrophobicity, and swarming motility as well as the production of exopolysaccharide (EPS). A significant reduction in AHL secretion and pslA gene expression was observed, indicating that the extract inhibited quorum sensing by disrupting the quorum-sensing systems. The quorum-sensing inhibitory effect of N. curviflora extract appears to be attributed to the presence of kaempferol, quercetin, salicylic acid, rutin, and rosmarinic acid, as indicated by LCMS analysis. Conclusion: The results of the present study provide insight into the potential of developing anti-quorum sensing agents using the extract and the identified compounds to treat infections resulting from quorum sensing-mediated bacterial pathogenesis.