• Title/Summary/Keyword: innervation

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Effect of Aconitine upon Autonomic Nervous System in Isolated Rabbit Intestine (Aconitine이 가토(家兎)의 장관지배신경(腸管支配神經)에 미치는 영향(影響))

  • Lee, Chang Eop;Rhee, Young So;Chung, Soon Tong
    • Korean Journal of Veterinary Research
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    • v.15 no.2
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    • pp.199-201
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    • 1975
  • In order to investigate the effect of aconitine upon the parasympathetic innervation, the isolated rabbit duodenal preparation pretreated with atropine and tetrodotoxin were observed. The results obtained in this work were summerized as follows: 1. The excitatory response was evoked by the administration of aconitine ($100{\mu}g/ml$). 2. The contraction was blocked by the pretreatment with atropine ($10{\mu}g/ml$). 3. The contraction was completely blocked by the pretreatment with tetrodotoxin($10{\mu}g/ml$). These experimental evidences indicate that the excitatory response by aconitine is due to the parasympathetic nerves.

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The Effect of Ganglion Impar Block for Neoplastic Perineal Pain with Coccygeal Fracture -A case report- (미골골절이 있는 암성 회음부통증 환자에 시행한 외톨이 교감신경절 차단 -증례 보고-)

  • Lee, Sung-Keun;Cha, Young-Deog;Suk, Min-Ho
    • The Korean Journal of Pain
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    • v.10 no.2
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    • pp.250-253
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    • 1997
  • The perineum is comprised of diverse anatomic structures with mixed sympathetic and somatic innervation. The coccyx is innervated by the coccygeal nerves and branches of the fifth sacral root. Recently, ganglion impar block has been introduced as an alternative means of managing intractable pain of sympathetic origin, coccygodynia by trauma, tenesmus and perineal hyperhydrosis. We managed a 59-year-old female patient who had suffered from perineal pain by metastasis of cervical cancer. Approach to impar ganglion through the anococcygeal ligament was impossible because her coccyx was hyperflexed anteriorly by old fracture. But we could perform ganglion impar block successfully by approach through the separation of sacrum and coccyx.

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Three Cases of Horner's syndrome after Neck Mass Removal (경부종물 제거후 발행한 Horner씨 증후군 치험 3례)

  • Kim Young-Min;Moon You-Bo;Kim Ic-Tae;Park Young-Min
    • Korean Journal of Head & Neck Oncology
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    • v.10 no.2
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    • pp.212-217
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    • 1994
  • The Horner's syndrome includes anisocoria as a result of miosis of the involved pupil with ptosis of the upper and lower lids, which results in slight narrowing of the palpebral fissure. Ipsilateral facial hyperemia and anhidrosis over the face and neck are less common features. The findings with Horner's syndrome are a result of the loss of sympathetic innervation to the ipsilateral eye and face. Recently we experienced 3 cases of Horner's syndrome that developed postoperatively and report briefly with literature.

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Mandibular osteonecrosis following herpes zoster infection in the mandibular branch of the trigeminal nerve: a case report and literature review

  • Song, Jae-Min;Seo, Jeong-Seok;Lee, Jae-Yeol
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.6
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    • pp.357-360
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    • 2015
  • Herpes zoster virus (HZV) infections are caused by reactivation of the varicella zoster virus. Reactivation symptoms commonly affect the thoracolumbar trunk, and rarely affect the mandibular branches of the trigeminal nerve. When the mandibular branches are involved, lesions appear proximal to the innervation area. This condition may be associated with exfoliation of the teeth and osteonecrosis of the jawbone. We report a case of mandibular osteomyelitis after herpes zoster infection and we present a review of the literature on mandibular-branch involvement of HZV-related osteonecrosis.

A Case of Treatment of Blepharoptosis (痲痺性 斜視로 因한 上瞼下垂 患者 1例에 對한 臨床的 考察)

  • Yu Mi-koung;Jeong Dong-hwan;park Su-yeon;Choi Jung-hwa;Kim Jong-han
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.2
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    • pp.159-164
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    • 2004
  • Blepharoptosis is the state that upper eyelid sagges, palpebal fissure becomes narrow due to disorder of a levator palpebrae superioris or innervation. It affects not only the physical vision but also mental shrink. In the view of oriental medicine, there are various causes, among them mainly cause is the deficiency of spleen Gi. The other hand, we treated a patient who suffered from blepharoptosis(with headache, exotropia, dizziness) differentiate from stagnation of Gi(energy) and blood stasis with Sungihwalhyeoltang(順氣活血湯) mostly. After about 40days of Sungihwalhyeoltang(順氣活血湯) centered treatment, acupunture, we observed an improvement Based on this experience, it is considered that stagnation of Gi(energy) and blood stasis can bring about blepharoptosis.

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The effect of substance P on the secretion of interleukin-8 and MCP(Monocyte Chemoattractant Protein)-1 from human dental pulp cells

  • Park, Sang-Hyuk;Choi, Gi-Woon;Park, Sang-Jin
    • Proceedings of the KACD Conference
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    • 2003.11a
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    • pp.548-549
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    • 2003
  • Neurogenic inflammation has been recognized to play an important role in initiating and sustaining of pulp inflammation. The pulpal innervation may modulate several aspects of the inflammatory response via secretion of neuropeptides. In this present study, these neuropeptides that may be questioned about roles in recruiting leukocytes by inducing the release of the chemokine IL-8 in the pulp during inflammation were tested. The response of human pulp cells in releasing IL-8 after the stimulation with SP and/or CGRP were investigated.(omitted)

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Bilateral sternocleidomastoid variant with six distinct insertions along the superior nuchal line

  • Dupont, Graham;Iwanaga, Joe;Altafulla, Juan J.;Lachkar, Stefan;Oskouian, Rod J.;Tubbs, R. Shane
    • Anatomy and Cell Biology
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    • v.51 no.4
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    • pp.305-308
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    • 2018
  • Anatomical variations of the sternocleidomastoid muscle (SCM) have been observed to occupy multiple origins and insertion points and have supernumerary heads, sometimes varying in thickness. During routine dissection, a SCM was observed to have six distinct insertions that interface with the course of the superior nuchal line, ending at the midline, bilaterally. This variation was also seen to receive innervation from the accessory nerve as well as the great auricular nerve. To our knowledge, this variant of supernumerary insertions and nerve innervations has not yet been reported. These variants may pose as problematic during surgical approaches to the upper neck and occiput, and should thus be appreciated by the clinician. Herein we discuss the case report, possible embryological origins, and the clinical significance of the observed variant SCM.

Thorax masculinization in a transsexual patient: Inferior pedicle mastectomy without an inverted T scar

  • Cely, Adriana Marcela Gonzalez;Triana, Carlos Enrique;Triana, Lina Maria
    • Archives of Plastic Surgery
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    • v.46 no.3
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    • pp.262-266
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    • 2019
  • Transsexual individuals with gender dysphoria or gender identity disorder are rare, with a prevalence reported to range from 0.002% to 0.014%. Studies have shown that mastectomy yields significant improvements in body image and self-esteem in female-to-male transsexual patients. In patients with grade III breast ptosis, mastectomy with a nipple-areolar complex (NAC) graft is the most commonly used technique, although it has several disadvantages. In the case described herein, a bilateral mastectomy preserving the NAC in an inferior pedicle was performed. Additionally, a thin superior thoracic dermal-fat flap was preserved and eventually sutured at the previous inframammary fold, preventing an inverted T scar. This case shows the advantage of this technique for preserving the blood supply and innervation of the NAC, with a low hypopigmentation risk. Furthermore, in this technique, the patch effect does not impair the results of the NAC graft, and there is no need to use an inverted T scar that may result in thoracic feminization.

Sensory nerve and neuropeptide diversity in adipose tissues

  • Gargi Mishra;Kristy L. Townsend
    • Molecules and Cells
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    • v.47 no.2
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    • pp.100030.1-100030.14
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    • 2024
  • Both brown and white adipose tissues (BAT/WAT) are innervated by the peripheral nervous system, including efferent sympathetic nerves that communicate from the brain/central nervous system out to the tissue, and afferent sensory nerves that communicate from the tissue back to the brain and locally release neuropeptides to the tissue upon stimulation. This bidirectional neural communication is important for energy balance and metabolic control, as well as maintaining adipose tissue health through processes like browning (development of metabolically healthy brown adipocytes in WAT), thermogenesis, lipolysis, and adipogenesis. Decades of sensory nerve denervation studies have demonstrated the particular importance of adipose sensory nerves for brown adipose tissue and WAT functions, but far less is known about the tissue's sensory innervation compared to the better-studied sympathetic nerves and their neurotransmitter norepinephrine. In this review, we cover what is known and not yet known about sensory nerve activities in adipose, focusing on their effector neuropeptide actions in the tissue.

Effect of Baclofen on the Cholinergic Nerve Stimulation in Isolated Rat Detrusor (흰쥐의 적출배뇨근에서 baclofen의 콜린성신경 억제작용)

  • Lee, Kwang-Youn;Lee, Keun-Mi;Choi, Eun-Mee;Choi, Hyoung-Chul;Ha, Jeoung-Hee;Kim, Won-Joon
    • Journal of Yeungnam Medical Science
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    • v.12 no.2
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    • pp.246-259
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    • 1995
  • This study aimed to investigate the mechanism of action of baclofen on the detrusor muscle isolated from rat. Rats (Sprague-Dawley) were sacrificed by decapitation and exsanguination. Horizontal muscle strips of $2mm{\times}15mm$ were prepared for isometric myography in isolated muscle chamber bubbled with 95% / 5%-$O_2$ / $CO_2$ at $37^{\circ}C$, and the pH was maintained at 7.4. Detrusor strips contracted responding to the electrical field stimulation (EFS) by 2 Hz, 20 msec, monophasic square wave of 60 VDC. The initial peak of EFS-Induced contraction was tended to be suppresed by ${\alpha},{\beta}$-methylene-adenosine 5'-triphosphate (mATP), a partial agonist of purinergic receptor, and baclofen, a $GABA_B$ receptor agonist (statistically nonsignificant). The late sustained contraction by EFS was suppressed significantly (p < 0.05) by additions of atropione, a cholinergic muscarinic receptor antagonist and baclofen. The adenosine 5'-triphosphate-induced contraction was completely abolished by mA TP but not by baclofen. In the presence of atropine, the subsequent addition of acetylcholine could not contract the muscle strips: but the addition of acetylcholine in the presence of baclofen evoked a contraction to a remarkable extent. These results suggest that in the condition of present study, the cholinergic innervation may play a more important role than the purinergic one, and baclofen suppresses the contractility of rat detrusor by the stimulation of the $GABA_B$ receptors to inhibit the release of neurotransmitter from the cholinergic nerve ending.

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